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Phenolic extract from Ocimum basilicum restores lipid metabolism in Triton WR-1339-induced hyperlipidemic mice and prevents lipoprotein-rich plasma oxidation

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Food Science and Human Wellness 2017年第1期6卷 28-33页

作者： Ilham Touiss saloua Khatib Oussama Bekkouch Souliman Amrani Hicham Harnafi Laboratory of Biochemistry and Biotechnologies Department of BiologyFaculty of Sciences60000 OujdaMorocco

In this study we investigated the hypolipidemic and anti-lipoprotein-oxidation activities of phenolic extract from sweet basil a popular culinary *** hypolipidemic activity was studied in mice model injected intraperitoneally with Triton WR-1339 at a dose of 200 mg/kg body *** animals were grouped as follows:normolipidemic control group(n=8),hyperlipidemic control group(n=8)and phenolic extract-treated group(n=8)at a dose of 200 mg/kg body *** 7 h and 24 h treatment,the oral administration of the phenolic extract exerts a significant reduction of plasma total cholesterol,triglycerides and LDL-cholesterol concentrations(P<0.001).On the other hand,we demonstrated that the phenolic extract prevents plasma lipid oxidation by 16%(P<0.001),20%(P<0.001),32%(P<0.001)and 44%(P<0.001)at a doses of 10,25,50 and 100g/mL,*** results were compared with ascorbic acid used as standard synthetic *** analysis shows that the extract contains 4 major phenolics and is especially rich in rosmarinic *** finding indicates that the phenolic extract might be beneficial in lowering hyperlipidemia and preventing atherosclerosis.

关键词： Sweet basil Phenolic acids Hypocholesterolaemia Hypotriglyceridaemia Lipoprotein-rich plasma oxidation

Complications and its risk factors of percutaneous subclavian vein catheters in pediatric patients:enhancing the outcomes of a university hospital in a low-income and middle-income country

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World Journal of Pediatric Surgery 2023年第1期6卷 36-41页

作者： Anouar Jarraya Manel Kammoun Ameni Chtourou saloua Ammar Kamel Kolsi The Anesthesiology department University of Sfax Faculty of Medicine of SfaxSfaxTunisia Department of Pediatric Surgery Hedi Chaker HospitalSfaxTunisia University of Sfax Faculty of Medicine of Sfax SfaxTunisia

Objective Assessing central venous catheter-related complications with regular feedback and investigating risk factors are mandatory to enhance *** aim of this study is to assess our experience in the management of pediatric subclavian vein catheters(SVCs)and to investigate the main risk factors for *** In this prospective observational study,we included children aged 3 months to 14 years who underwent infraclavicular subclavian vein catheterization consecutively using the anatomic landmark *** were divided into two groups:group 1 included complicated catheters and group 2 included noncomplicated *** management protocol was standardized for all *** comparing the two groups,univariate and multivariate logistic regression were used to investigate the risk factors for *** In this study,we included 134 pediatric *** rate of complications was 32.8%.The main complications were central line-associated bloodstream infection(63.6%),bleeding and/or hematoma(22.7%),mechanical complications(13.6%),and vein thrombosis(13.6%).After adjustment for confounding factors,predictors of catheter-related complications were difficult insertion procedure(adjusted odds ratio(aOR)=9.4;95%confidential interval(CI):2.32 to 38.4),thrombocytopenia(aOR=4.43;95%CI:1.16 to 16.86),comorbidities(aOR=2.93;95%CI:0.58 to 14.7),and neutropenia(aOR=5.45;95%CI:2.29 to 13.0).Conclusions High rates of complications were associated with difficult catheter placement and patients with comorbidities and severe *** reduce catheter-related morbidity,we suggest an ultrasoundguided approach,a multidisciplinary teaching program to improve nursing skills,and the use of less invasive devices for patients with cancer.

关键词： patients catheter pediatric

Predictors of perioperative respiratory adverse events among children with upper respiratory tract infection undergoing pediatric ambulatory ilioinguinal surgery:a prospective observational research

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World Journal of Pediatric Surgery 2023年第2期6卷 97-102页

作者： Anouar Jarraya Manel Kammoun saloua Ammar Wiem Feki Kamel Kolsi The anesthesiology Department Hedi Chaker University HospitalUniversity of SfaxSfaxTunisia Faculty of Medicine of Sfax University of SfaxSfaxTunisiaFaculty of Medicine of SfaxUniversity of SfaxSfaxTunisia Department of Pediatric Surgery Hedi Chaker HospitalSfaxTunisiaFaculty of Medicine of SfaxUniversity of SfaxSfaxTunisia

Objectives Anesthesia for children with an upper respiratory tract infection(URI)has an increased risk of perioperative respiratory adverse events(PRAEs)that may be predicted according to the COLDS *** aims of this study were to evaluate the validity of the COLDS score in children undergoing ilioinguinal ambulatory surgery with mild to moderate URI and to investigate new predictors of *** This was a prospective observational study including children aged 1-5 years with mild to moderate symptoms of URI who were proposed for ambulatory ilioinguinal *** anesthesia protocol was *** were divided into two groups according to the incidence of *** logistic regression was performed to assess predictors for *** In this observational study,216 children were *** incidence of PRAEs was 21%.Predictors of PRAEs were respiratory comorbidities(adjusted OR(aOR)=6.3,95%CI 1.19 to 33.2;p=0.003),patients postponed before 15 days(aOR=4.3,95%CI 0.83 to 22.4;p=0.029),passive smoking(aOR=5.31,95%CI 2.07 to 13.6;p=0.001),and COLDS score of>10(aOR=3.7,95%CI 0.2 to 53.4;p=0.036).Conclusions Even in ambulatory surgery,the COLDS score was effective in predicting the risks of *** smoking and previous comorbidities were the main predictors of PRAEs in our *** seems that children with severe URI should be postponed to receive surgery for more than 15 days.

关键词： surgery ambulatory respiratory

Crystal Structure and Physicochemical Properties of a New Tris (2-Amoniumbenzamide) Sulfate (C7H9N2O)3HSO4SO4

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Open Journal of Inorganic Chemistry 2015年第4期5卷 112-121页

作者： saloua Belghith Sondes Chmengui Latifa Ben Hamada Laboratoire d’Energie et de Matériaux (LabEM) Ecole Supérieure des Sciences et de la Technologie de Hammam Sousse Tunisia

Physicochemical properties of a new hybrid compound (C7H9N2O)3HSO4SO4 are synthesized in aqueous solution and characterized by various physicochemical studies. This compound crystallizes in the monoclinic space group P21/c and a unit cell with a = 10.3028(2)A°, b = 12.4995(2)A°, c = 20.6730(2)A°, V = 2600.61(7)A°3, and Z = 8. The structure has been solved using direct method and refined to a reliability R factor of 4.6%. The atomic arrangement of this compound is built up by (HS2O8)3- anionic pairs interconnected with two types (C7H9N2O)22+ cationic pairs via (N, O)-H...O hydrogen bonds. The characterization of these salts was carried out using X-ray diffraction, IR spectroscopy and thermal analysis.

关键词： Chemical Preparation Crystal Structure Thermal Behaviour Infrared Spectroscopy 2-Aminobenzamide

Synthesis, Crystal Structure and Characterization of a New Dihydrogenomonophosphate: (C7H9N2O)H2PO4

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Open Journal of Inorganic Chemistry 2015年第4期5卷 122-130页

作者： saloua Belghith Yahya Bahrouni Latifa Ben Hamada Laboratoire d’Energie et de Matériaux (LabEM-LR11ES34) Ecole Supérieure des Sciences et de la Technologie de Hammam Sousse Tunisia

Chemical preparation, X-ray single-crystal, thermal behavior, and IR spectroscopy investigations are given for a new organic cation dihydrogenomonophosphate (C7H9N2O)H2PO4 (denoted ABHP) in the solid state. This compound crystallizes in the monoclinic space group P21/n. The unit cell dimensions are: a = 11.011(5) Å, b = 5.861(1) Å, c = 15.944(4) Å and β = 100.81(5) with V = 1010.7(6) Å3 and Z = 4. The structure has been solved using direct method and refined to a reliability R factor of 0.048. The atomic arrangement can be described as inorganic clusters [H4P2O8]2- anions between which are located the organic dimmers (C14H18N4O2)2+ through multiple hydrogen bonds (Figure 1)

关键词： Chemical Synthesis X-Ray Diffraction H-Bonds Differential Thermal Analysis Infrared Spectroscopy

Hyperbaric Oxygen Therapy: Focus

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Open Journal of Emergency Medicine 2018年第1期6卷 15-20页

作者： Ahmed Amine El Oumri Hiba Badi saloua Khaloufi Physical Medicine and Rehabilitation Unit Oujda University Hospital Oujda Morocco Faculty of Medicine Oujda Morocco Physical Medicine and Rehabilitation Unit HMVIM Rabat Morocco

Hyperbaric oxygen therapy is now an integral part of the current therapeutic arsenal, it is a treatment that has a large number of indications and which concerns several specialties. This development aims to summarize... 详细信息

关键词： Hyperbaric Oxygen Therapy

Tyrosinase Biosensor Used for the Determination of Catechin Derivatives in Tea: Correlation with HPLC/DAD Method

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Food and Nutrition Sciences 2013年第1期4卷 108-118页

作者： saloua Nadifiyine Carole Calas-Blanchard Aziz Amine Jean-Louis Marty Institut de Modélisation et d’Analyse en Géo-Environnement et Santé Univ. Perpignan Via Domitia Perpignan France Institut de Modélisation et d’Analyse en Géo-Environnement et Santé Univ. Perpignan Via Domitia Perpignan France&Laboratoire d’Analyses Chimiques et Biocapteurs Faculté des Sciences et Techniques Université Hassan II Mohammedia Morocco. Laboratoire d’Analyses Chimiques et Biocapteurs Faculté des Sciences et Techniques Université Hassan II Mohammedia Morocco.

Tea, one of the most popular consumed worldwide beverages, is known to be rich in polyphenols, more particularly in catechins. An amperometric biosensor based on tyrosinase was developed in order to monitor the phenolic content in black and green teas. The enzyme was immobilised by coreticulation with glutaraldehyde on carbon screen-printed electrodes (CSPE). Initially, the performances of the biosensor were evaluated referring to catechol as a model substrate. This analytical tool exhibits a high sensitivity (217 nA/μM), low limit of detection (LOD) = 0.03 μM, good intra-electrode and inter-electrode reproducibilities with RSD lower than 3% (n = 5 injections) and RSD = 8.14% (n = 12 sensors) respectively. The storage stability was also studied;the biosensor retained successively 85% and 70% of its initial response after 34 and 53 days. Subsequently, several catechin derivatives frequently found in teas were tested and classified relatively to their sensitivities. For tea samples, the results obtained with the biosensors were compared to high performance liquid chromatography (HPLC) analysis. A good correlation between the two methods was obtained. The calculated recovery was between 90% and 96%, proving that the proposed tyrosinase biosensor can be an alternative analytical tool for global determination of catechin derivatives in tea.

关键词： Tea Polyphenol Catechin Tyrosinase Amperometric Biosensor HPLC

Robust Control of Time Delay Systems

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Computer Technology and Application 2012年第1期3卷 69-75页

作者： Farhati Samia Bel Hadj All Naoui saloua Abdelkrim Mohamed Naceur Modeling Analysis and Control of Systems National Engineering School of Gabes Street lbn E1 Khatab Zrig 6029 Gabes Tunisia

This study presents the design of both H∞ Loop Shaping Control （HLSC） and Internal Model Control （IMC） strategies for linear time delay systems. For first order time delay system, a systematic approach for weight selection based on the sensitivity function was proposed, then compared to the internal model control strategy. For both methods, the synthesis was based on the Pade approximation. Two cases are considered for time delay： upper or lower than system time constant. Simulation results for the proposed approaches are acceptable ever in presence of disturbances and model mismatches.

关键词： H∞ loop shaping control internal model control sensitivity function constant delay Pade approximation model mismatches.

Electrosynthesis, Characterization and Electrocatalytic Behaviour of Organic-Metal Thin-Films Based on 2,2’-Bithiophene-5-carboxylic Acid and Metal Ions

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American Journal of Analytical Chemistry 2014年第3期5卷 165-172页

作者： Naima Maouche Belkacem Nessark saloua Chelli Salah Aeiyach Idriss Bakas Département de Génie des Procédés Faculté de Technologie Université de Sétif Sétif Algeria Laboratoire Interfaces Traitements Organisation et Dynamique des Systèmes Université Paris Paris France

2,2’-Bithiophene-5-carboxylic acid (BTA) thin-films on platinum (Pt) electrodes were electrochemically prepared in acetonitrile solution containing 0.1 M tetrabutylammonium perchlorate (TBAP) and 0.05 M BTA. These films were complexes with several metal ions such as Cu2+, Ag+ and Co2+. Their structural characteristics were compared with those of powder complexes chemically prepared from BTA and the corresponding metal ion. IR and XPS techniques reveal that the film complexes with metal ions have the same structures as the corresponding powder complexes. The electrocatalytic activity of BTA film-metal ions has been investigated toward ascorbic acid (AA) oxidation and compared to that obtained on a free BTA film. BTA film-metal ions exhibit good catalytic proprieties and better detection of AA than a free BTA film. This new propriety allows these films to be used as electrochemical sensors. This electronic document is a “live” template. The various components of your paper [title, text, heads, etc.] are already defined on the style sheet, as illustrated by the portions given in this document.

关键词： 2 2’-Bithiophene-5-carboxylic Acid Metal Ions Cyclic Voltammetry IR and XPS Electrocatalytic Activity Ascorbic Acid