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Resolution Enhancement of Optical Surface Plasmon Resonance Sensor Using Metamaterial

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Photonic Sensors 2015年第4期5卷 330-338页

作者： Sarika PAL Y. K. PRAJAPATI J. P. saini V. SINGH Sarika Pal Department of Electronics & Communication Engineering KIET Ghaziabad (U.P.) India yogendra Kumar Prajapati Department of Electronics & Communication Engineering MNNIT Allahabad-211004 (U.P.) India jai Prakash saini Department of Electronics & Communication Engineering BIET Jhansi-284128 (U.P.) India Vivek Singh Department of Physics Faculty of Science Banaras Hindu University Varanasi (U.P.) India

In this paper, we present and discuss a an optical surface plasmon resonance （SPR） path to extend the enhancement of the resolution of sensor. Basically, our approach is to combine bi-metamaterial layers to design the SPR sensor. The calculation shows that the proposed SPR sensor structure has a preference over the conventional SPR sensors and bimetallic SPR sensors since it gives a much sharper reflectance dip and can achieve considerable sensitivity improvement when compared to the recently reported investigations. The effects of the metamaterial permittivity, permeability, and thickness on the reflectance curve are studied. It is also seen that metamaterial layers improve the field of the proposed SPR structure, which may provide a novel tool to significantly enhance the sensitivity and resolution of the sensors.

关键词： Surface plasmon resonance sensor metamaterials Fresnel equations reflectance

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灾害应对措施下的北京道路拥堵时空变化

灾害学 2024年第4期39卷 185-191页

作者：刘晓燕杨赛霓汪伟平周子滢刘欢焦振寰石永国北京师范大学环境演变与自然灾害教育部重点实验室北京100875 教育部巨灾模拟与系统性风险应对国际合作联合实验室广东珠海519087 北京师范大学国家安全与应急管理学院北京100875 京都大学防灾研究所日本京都611-0011 北京市昌平区水文水质监测中心北京102200 浙江省应急管理科学研究院浙江杭州310012 浙江省安全工程与技术研究重点实验室浙江杭州310012

暴雨灾害给城市正常运转带来了巨大挑战,道路交通由于直接暴露在户外、承载多种出行方式和海量刚需活动,需要重点关注与积极应对。该研究以北京五环内为研究区,使用精细的道路拥堵数据,从时空维度评价了2021年北京最大暴雨事件及多种应... 详细信息

暴雨灾害给城市正常运转带来了巨大挑战,道路交通由于直接暴露在户外、承载多种出行方式和海量刚需活动,需要重点关注与积极应对。该研究以北京五环内为研究区,使用精细的道路拥堵数据,从时空维度评价了2021年北京最大暴雨事件及多种应对措施下的交通状况。结果表明:①道路拥堵在常态下具有鲜明的日际、周际规律,而降雨和应对措施会导致极其显著的变化;②拥堵变化的时间序列呈现对勾形态,即暴雨当日拥堵缓解,而前后日拥堵加重,体现了应对措施的阶段性效果;③城市内部的拥堵变化具有空间异质性,暴雨当日北部和东部地区的拥堵大幅缓解,而次日拥堵整体加重且高度聚集;④分时段分区域统计显示,早高峰和环线的拥堵变化最为强烈;⑤相关性分析识别了应对措施的有效作用对象,证实了众多行业部门对于暴雨预警的积极响应以及弹性上下班建议的执行成效。研究发现,暴雨应对措施在局部上有效减轻了交通压力,但伴随的拥堵转移现象需要在实施应对措施前被充分考虑。

关键词：暴雨应对城市道路交通弹性出行多源数据时空分析

Assessment of colistin resistance in Gram negative bacteria from clinical samples in resource-limited settings

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Asian Pacific Journal of Tropical Medicine 2022年第8期15卷 367-373,I0011-I0013页

作者： Shubham Chauhan Narinder Kaur Adesh K.saini Jyoti Chauhan Harit Kumar Department of Microbiology Maharishi Markandeshwar Institute of Medical Sciences and ResearchMaharishi Markandeshwar(Deemed to be)UniversityMullanaAmbalaIndia Department of Biotechnology Maharishi Markandeshwar Engineering CollegeMaharishi Markandeshwar(Deemed to be)UniversityMullanaAmbalaIndia

Objective:To find a proper method to assess colistin resistance in multidrug resistant Gram negative bacteria(MDR-GNB)on a routine basis in resource limited ***:Clinical samples were ***-GNB were identified and were examined for colistin resistance by colistin broth elution method,colistin agar method,and colistin disk elution screening *** microdilution method was used the gold ***:A total of 10235 clinical samples were processed,in which 857(8.4%)MDR-GNB were *** very significant errors,categorical agreement,major errors,positive predictive values,negative predictive values,specificity and sensitivity of all the phenotypic methods were 5.5%,0%,94.4%,100%,99.6%,100%and 94.4%,respectively for the detection of colistin *** colistin elution screening method was cheap and easy to perform with similar results to broth microdilution ***:All the evaluation methods for colistin resistance showed similar *** the laboratories can choose any method for detection of colistin ***,we recommend colistin disk elution screening method because,it is easy and cheap and can be performed in limited resources.

关键词： Multi-drug resistant organism Colisitin resistance mcr gene Broth micro dilution Disk elution method

Ocular surface evaluation in eyes with chronic glaucoma on long term topical antiglaucoma therapy

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International Journal of Ophthalmology(English edition) 2017年第6期10卷 931-938页

作者： Manu saini Murugesan Vanathi Tanuj Dada Tushar Agarwal Rebika Dhiman Sudarshan Khokhar Cornea ＆ Ocular Surface Services Dr R P Centre for Ophthalmic Sciences All India Institute of Medical Sciences New Delhi 110029 India

AIM： To evaluate ocular surface changes and its correlation with the central corneal subbasal nerve fibre layer in chronic glaucoma patients. METHODS： A prospective comparative study of ocular surface evaluation was performed in 50 eyes of 25 patients using two or more antiglaucoma medications for at least 6too and 50 eyes of 25 normal subjects without any ocular problems as controls. The study parameters evaluated included visual acuity, intraocular pressure, ocular surface evaluation parameters [fluorescein break-up time （FTBUT）, Schirmer＇s I test, ocular surface staining scores and ocular surface disease index score （OSDI）], central corneal sensation （Cochet Bonnett aesthesiometer）, central subbasal nerve fiber layer density （SBNFLD） by confocal microscopy. RESULTS： The mean values in the glaucoma cases and control groups respectively were as follows： OSDI score （35.89±16.07/6.02±3.84; P=-0.001）, Schirmer＇s I test score （7.632.64 mm/12.86±1.93 mm; P=-0.001）, FTBUT （9.442.76s/11.8±1.88s; P=0.001）, corneal （5.7±2.33/ 1.1±0.58; P=0.001） and conjunctival staining score （5.061.94/0.84±0.46; P=0.001）, corneal sensitivity （4.68±0.44/5.07±0.37; P=0.076）, mean subbasal nerve fiber number （3.58±0.99/5.40±1.70; P=0.001）, SBNFL length （1101.44±287.56 pm/1963.70±562.56 pro; P=0.001） and density （6883.941798.03 pm/mm/12 273.153516.04 pm/mm2; P=O.O01）. Dry eye severity of level 2 and 3 was seen in 66% of glaucoma group. Corneal （/=0.86） and conjunctival staining （R2=0.71） and OSDI score （R=0.67） showed statistically significant negative correlation with central corneal SBNFLD while FTBUT （R==0.84）, corneal sensitivity （/=0.52） showed positive correlation to central corneal SBNFLD in the long term topical antiglaucoma medication group. CONCLUSION： Ocular surface changes and antiglaucoma therapy induced dry eye is found to be associated with decreased SBNFLD in eyes on long term topical antiglaucoma medications.

关键词： confocal microscopy glaucoma ocularsurface disease subbasal nerve fiber layer therapy

Current trends of antibiotic resistance in clinical isolates of Staphylococcus aureus

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Frontiers in Biology 2014年第4期9卷 287-290页

作者： Kapil Dev SHARMA Rajendra Prasad saini Loganathan KARTHIK Dhanwantri Hospital and Research Centre Jaipur Rajasthan India Department ofBiosciences Shri Jagdishprasad Jhabarmal Tibrewala University Jhunjhunu Rajasthan 333 001 India

Staphyloccus aureus （S. aureus） is a well known human pathogen known to causes a verity of infections in humans. In recent years S. aureus is reported to show drug resistant toward commonly known drugs. Therefore, this study was designed to study the pattern of antibiotic resistance in 50 clinical isolates ofS. aureus isolated at Dhanwantri Hospital and Research Centre, Jaipur, Rajasthan, India. S. aureus cultures were isolated from different clinical samples, pus, throat swabs and urine on Blood agar and MacConkey agar and Chrom agar plats and characterized by an array of microscopic and biochemical tests. Antibiotic sensitivity test was performed by standard disc diffusion method （Kirby bayer＇s method） on Muller Hinton agar plates. During this study, among 50 S. aureus isolates 48 （96%） were found to be resistance toward Aztreonam and Doxicycline followed by Ciprofloxacin （n = 45, 90%）, Cefpodoxime and Ceftazidime （n = 44, 88%）, Cefuroxime （n = 40, 80%）, Pipracillin ＋ Tazobactum （n = 38, 76%）, Cefoparazone （n = 36, 72%）, Amoxicillin ＋ Clavulanic acid and Ceftriaxone （n = 33, 66%）, Levofloxacin （n = 32, 64%）, Moxifloxacin （n = 31, 62%）, Ofloaxacin （n = 25, 50%）, Cloxacillin （n = 22, 44%）, Azithromycin （n = 21, 42%）, Clindamycin （n = 19, 38%）, Meropenem （n = 18, 36%）, Clarithromycin （n = 16, 32%）, Ampicillin ＋ sulbactam （n = 13, 26%）, Amikacin （n = 12, 24%）, Impipenem （n = 8, 16%）, Linezolid and Methicillin （n = 7, 14%） and Teicoplanin （n = 3, 6%）. In conclusion, the isolated S. aureus found to be resistant toward common antibiotics, however all isolates were found to be susceptible to Vancomycin.

关键词： Staphyloccus aureus infections antibiotic resistance

Human Factors While Using Head-Up-Display in Low Visibility Flying Conditions

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Intelligent Automation & Soft Computing 2023年第5期36卷 2411-2423页

作者： Jhulan Kumar Surender Singh saini Divya Agrawal Vinod Karar Aman Kataria Academy of Scientific and Innovative Research(AcSIR) Ghaziabad201002India CSIR-Central Scientific Instruments Organisation 160030India

Flying an aircraft in low visibility is still a challenging task for the *** requires precise and accurate situational awareness(SA)in real-time.A Head-up Display(HUD)is used to project collimated internal and externalﬂight information on a transparent screen in the pilot’s forwardﬁeld of view,which eliminates the change of eye position between Head-Down-Display(HDD)instru-ments and outer view through the *** of HUD increases the SA and reduces the workload for the *** to provide a betterﬂying capability for the pilot,projecting extensive information on HUD causes human factor issues that reduce pilot performance and lead to accidents in low visibility *** literature shows that human error is the leading cause of more than 70%of aviation *** this study,the ability of the pilot able to read background and symbology information of HUD at a different level of back-ground seen complexity,such as symbology brightness,transition time,amount of Symbology,size etc.,in low visibility conditions is *** result shows that increased complexity on the HUD causes more detection errors.

关键词： HUD avionics human factor situational awareness background complexity

Hybrid Whale Optimization Algorithm for Resource Optimization in Cloud E-Healthcare Applications

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Computers, Materials & Continua 2022年第6期71卷 5659-5676页

作者： Punit Gupta Sanjit Bhagat Dinesh Kumar saini Ashish Kumar Mohammad Alahmadi Prakash Chandra Sharma School of Computing&Information Technology Manipal University JaipurJaipur303007India School of Basic Sciences Manipal University JaipurJaipur303007India Department of Software Engineering College of Computer Science and EngineeringUniversity of JeddahJeddah23218Saudi Arabia

In the next generation of computing environment e-health care services depend on cloud *** Cloud computing environment provides a real-time computing environment for e-health care *** these services generate a huge number of computational tasks,real-time computing and comes with a deadline,so conventional cloud optimizationmodels cannot fulfil the task in the least time and within the *** overcome this issue many resource optimization meta-heuristic models are been proposed but these models cannot find a global best solution to complete the task in the least time and manage utilization with the least simulation *** order to overcome existing issues,an artificial neural-inspired whale optimization is proposed to provide a reliable solution for healthcare *** this work,two models are proposed one for reliability estimation and the other is based on whale optimization technique and neural network-based binary *** predictive model enhances the quality of service using performance metrics,makespan,least average task completion time,resource usages cost and utilization of the *** as compared to existing algorithms the proposedANN-WHOalgorithms prove to improve the average start time by 29.3%,average finish time by 29.5%and utilization by 11%.

关键词： Cloud computing whale optimization health care resource optimization

The Gondwana Orogeny in northern North Patagonian Massif:Evidences from the Caita Có granite, La Se?a and Pangaré mylonites,Argentina

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Geoscience Frontiers 2016年第4期7卷 621-638页

作者： Daniel A.Gregori Bernhardt saini-Eidukat Leonardo Benedini Leonardo Strazzere Mercedes Barros José Kostadinoff Cátedra de Geología Argentina Departamento de Geología Universidad Nacional del Sur and INGEOSUR Department of Geosciences North Dakota State University Cátedra de Campos Gravitacionales Departamento de Física Universidad Nacional del Sur

Structural analyses in the northern part of the North Patagonia Massif, in the foliated Caita Co granite and in La Sefia and Pangare mylonites, indicate that the pluton was intruded as a sheet-like body into an opening pull-apart structure during the Gondwana Orogeny. Geochronological studies in the massif indicate a first, lower to middle Permian stage of regional deformation, related to movements during indentation tectonics, with emplacement of foliated granites in the western and central areas of the North Patagonian Massif. Between the upper Permian and lower Triassic, evidence indicates emplacement of undeformed granitic bodies in the central part of the North Patagonian Massif. A second pulse of deformation between the middle and upper Triassic is related to the emplacement of the Caita CO granite, the development of mylonitic belts, and the opening of the Los Menucos Basin. During this pulse of deformation, compression direction was from the eastern quadrant.

关键词： Gondwana Orogeny Northern Patagonia Foliated granite Mylonites Argentina

Tectonics induced switching of provenance during the Late Quaternary aggradation of the Indus River Valley, Ladakh, India

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Geoscience Frontiers 2019年第1期10卷 285-297页

作者： Ravish Lal H.S.saini N.C.Pant S.A.I.Mujtaba Department of Geology University of Delhi Geological Survey of India

The Indus River flows through Ladakh, one of the driest and coldest places on earth, in a tectonically active domain. Fluvial, glaciofluvial, lacustrine and debris dominated sequences represent the Late Quaternary sedimentary record along the river course. Karakoram Fault, a major crustal scaled feature reported to be active during the Quaternary, is associated with the Indus River drainage. Linkages between a major, active fault and deposits formed during the activity period of the fault are explored using heavy mineral deduced provenance and Optically Stimulated Luminescence(OSL) *** deposits in a ~200 km long stretch of the Indus River have been examined for a ~80 ka period to decipher the climate linked aggradation history. Damming of the Indus River at ~79 ka and existence of the Spituk Lake for >30 ka is demonstrated. Using geology of the provenance in relation to the mineralogical attributes of the Quaternary deposits, the major drainage reorganization when the connection of the Tangtse Valley to the Indus was blocked, is inferred at ~73 ka. It is supported by the geologicalgeomorphological evidence. The study demonstrates the application of provenance linked mineralogy in terrestrial aggradation in a tectonically active region.

关键词： Karakoram Fault Indus Drainage reorganization Heavy minerals Aggradation