检索结果-南通市图书馆

Uncovering genetic and metabolite markers associated with resistance against anthracnose fruit rot in northern highbush blueberry

引用

Horticulture Research 2023年第10期10卷 25-36页

作者： MacKenzie jacobs Samantha Thompson Adrian E.Platts Melanie j.A.Body Alexys Kelsey Amanda saad Patrick Abeli Scott j.Teresi Anthony Schilmiller Randolph Beaudry Mitchell j.Feldmann Steven j.Knapp Guo-qing Song Timothy Miles Patrick P.Edger Department of Biochemistry and Molecular Biology Michigan State UniversityEast LansingMI 48824USA Department of Horticulture Michigan State UniversityEast LansingMI 48824USA Molecular Plant Science Program Michigan State UniversityEast LansingMI 48824USA Department of Plant Soil and Microbial SciencesMichigan State UniversityEast LansingMI 48824USA Department of Horticulture and Natural Resources Kansas State UniversityOlatheKS 66061USA Genetics and Genome Sciences Program Michigan State UniversityEast LansingMI 48824USA Mass Spectrometry&Metabolomics Core Michigan State UniversityEast LansingMI 48824USA Department of Plant Sciences University of CaliforniaDavisCA 95616USA

Anthracnose fruit rot(AFR),caused by the fungal pathogen Colletotrichum fioriniae,is among the most destructive and widespread fruit disease of blueberry,impacting both yield and overall fruit *** cultivars have highly variable resistance against *** date,this pathogen is largely controlled by applying various fungicides;thus,a more cost-effective and environmentally conscious solution for AFR is *** we report three quantitative trait loci associated with AFR resistance in northern highbush blueberry(Vaccinium corymbosum).Candidate genes within these genomic regions are associated with the biosynthesis of flavonoids(***)and resistance against ***,we examined gene expression changes in fruits following inoculation with Colletotrichum in a resistant cultivar,which revealed an enrichment of significantly differentially expressed genes associated with certain specialized metabolic pathways(*** biosynthesis)and pathogen *** non-targeted metabolite profiling,we identified a flavonol glycoside with properties consistent with a quercetin rhamnoside as a compound exhibiting significant abundance differences among the most resistant and susceptible individuals from the genetic mapping *** analysis revealed that this compound exhibits significant abundance differences among the most resistant and susceptible individuals when analyzed as two ***,individuals within each group displayed considerable overlapping variation in this compound,suggesting that its abundance may only be partially associated with resistance against *** findings should serve as a powerful resource that will enable breeding programs to more easily develop new cultivars with superior resistance to AFR and as the basis of future research studies.

关键词： applying resistance specialized

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Giant chiro-optical responses in multipolar-resonances-based single-layer dielectric metasurfaces

引用

Photonics Research 2021年第9期9卷 1667-1674页

作者： HAFIZ saad KHALIQ INKI KIM AIMA ZAHID jOOHOON KIM TAEjUN LEE TREVON BADLOE YESEUL KIM MUHAMMAD ZUBAIR KASHIF RIAZ MUHAMMAD QASIM MEHMOOD jUNSUK RHO NanoTech Lab Department of Electrical EngineeringInformation Technology University(ITU)of the PunjabLahore 54600Pakistan Department of Mechanical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea POSCO-POSTECH-RIST Convergence Research Center for Flat Optics and Metaphotonics Pohang 37673Republic of Korea National Institute of Nanomaterials Technology(NINT) Pohang 37673Republic of Korea

Chiro-optical effects offer a wide range of potential applications in nanophotonics,such as advanced imaging and molecular sensing and *** single-layer metasurfaces composed of subwavelength meta-atoms have gained significant attention due to their exceptional characteristics in light–matter *** metasurface-based devices have manipulated electromagnetic waves,the compact on-chip realization of giant chiro-optical effects remains a challenge at optical *** this work,we experimentally and numerically demonstrate an all-dielectric metasurface to realize large chiro-optical effects in the visible ***,the proposed strategy of utilizing achiral nanofins instead of conventional chiral structures provides an extra degree of design *** mutual coupling between carefully engineered nanofins produces constructive and destructive interference,leading to the asymmetric transmission of 70%and average circular dichroism exceeding 60%.We investigate the underlying mechanism behind the chiro-optical effects using the theory of multipolar *** proposed design mechanism maximizes the chiro-optical response through a single-layer metasurface with potential applications in high-efficiency integrated ultrathin polarization rotators and shapers,chiral polarizers for optical displays,chiral beam splitters,and chiral sensors.

关键词： chiral dielectric polar

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Simple Quantitation of Flucytosine in Low Volume Serum Samples and Evaluation of Common Endogenous Interferences by HPLC-UV

引用

American journal of Analytical Chemistry 2022年第9期13卷 289-299页

作者： Abdul Rafiq Khan Ali Alothaim Waleed Tamimi Majid Alshaibani Souad Marwan Al Enazi Syed Muhammad saad Khalid Mohammed Khan Department of Pathology and Laboratory Medicine King Abdulaziz Medical City Riyadh KSA Department of Chemistry University of Karachi Karachi Pakistan H. E. j. Research Institute of Chemistry International Center for Chemical and Biological Sciences University of Karachi Karachi Pakistan

5-Fluorocytosine (5-FC) is used for the treatment of several infections. It is extremely important to monitor blood level concentration for maximum activity to avoid its side effects. A simple, faster, and more accurate analytical method is developed and validated using high-performance liquid chromatography with UV detection in a very low-volume serum sample. Exactly 50 μL of serum was precipitated with 5% trichloroacetic acid. After mixing and centrifugation, 20 μL of supernatant was injected into the HPLC column. Detection was performed at 280 nm. The method is very specific and free from interfering substances due to different drugs and their different circulating metabolites. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.50 μg/L and 1.0 μg/L, respectively. The method was linear in the range of 5 - 150 μg/L in the serum sample. In method comparison, the correlation coefficient r2 was 0.999 and the percentage recovery was 90% - 105% on four levels of the quality control samples. Within run and between run precision was found to be less than 2.2% at four different concentrations (5, 25, 50, and 100 μg/L). A simple, faster, and more accurate HPLC-UV method is developed which is very useful for monitoring 5-FC concentration in low volume serum samples without evaporation step and ion exchange chromatography within minutes.

关键词： 5-Fluorocytosine Serum Sample HPLC-UV Method Quantification Validation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Amifostine reduces LPS-induced lung dysfunction via suppression of redox-sensitive inflammatory signaling:a new role in the treatment of acute lung injury

Amifostine reduces LPS-induced lung dysfunction via suppress...

引用

中国中西医结合学会微循环2008学术大会

作者： Anna A．Birukova saad Sammani Dylan Burdette jeffrey S.Murley joe G．N．Garcia David j．Grdina Konstantin G．Birukov Section of Pulmonary and Critical Care Medicine Department of Medicine University of ChicagoChicagoIllinois 60637 Department of Radiation and Cellular Oncology University of ChicagoChicagoIllinois 60637

Multiple events are involved in the development of acute inflammation and injury in the lungs.A progressive rise of oxidative stress due to altered reduction-oxidation (redox) homeostasis appears to be one of the hallmarks of lung pathologies such as injury, inflammation and ischemia/***,despite the growing evidence that alteration of the redox balance in the lungs,antioxidant therapy may attenuate acute lung

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Effect of Substrates on the Properties of ZnO Thin Films Grown by Pulsed Laser Deposition

引用

Advances in Materials Physics and Chemistry 2013年第4期3卷 209-213页

作者： Adel Taabouche Abderrahmane Bouabellou Fouad Kermiche Faouzi Hanini Sarah Menakh Yacine Bouachiba Tahar Kerdja Chawki Benazzouz Mohamed Bouafia saad Amara Advanced Technology Development Center (CDTA) Baba-Hassen Algiers Algeria Center CRNA 2 Bd Franz Fanon Algiers Algeria Laboratory of Applied Optics Ferhat Abbas University Setif Algeria Thin Films and Interfaces Laboratory University of Constantine Constantine Algeria

Polycrystalline zinc oxide (ZnO) thin films have been deposited at 450°C onto glass and silicon substrates by pulsed laser deposition technique (PLD). The used source was a KrF excimer laser (248 nm, 25 ns, 5 Hz, 2 j/cm2). The effects of glass and silicon substrates on structural and optical properties of ZnO films have been investigated. X-ray diffraction patterns showed that ZnO films are polycrystalline with a hexagonal wurtzite—type structure with a strong (103) orientation and have a good crystallinity on monocrystalline Si(100) substrate. The thickness and compositional depth profile were studied by Rutherford Backscattering spectrometry (RBS). The average transmittance of ZnO films deposited on glass substrate in the visible range is 70%.

关键词： ZnO Thin Films PLD Silicon X-Ray Diffraction Optical Transmittance RBS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Real-world disease activity and sociodemographic,clinical and treatment characteristics of moderate-to-severe inflammatory bowel disease in Brazil

引用

World journal of Gastroenterology 2021年第2期27卷 208-223页

作者： Cyrla Zaltman Rogério Serafim Parra Ligia Yukie Sassaki Genoile Oliveira Santana Maria de Lourdes Abreu Ferrari Sender j Miszputen Heda M B S Amarante Roberto Luiz Kaiser junior Cristina Flores Wilson R Catapani joséMiguel Luz Parente Mauro Bafutto Odery Ramos Carolina D Gonçalves Isabella Miranda Guimaraes jose j R da Rocha Marley R Feitosa Omar Feres Rogerio saad-Hossne Francisco Guilherme Cancela Penna Pedro Ferrari Sales Cunha Tarcia NF Gomes Rodrigo Bremer Nones Mikaell Alexandre Gouvea Faria Mírian Perpétua Palha Dias Parente António S Scotton Rosana Fusaro Caratin juliana Senra júlio Maria Chebli Department of Internal Medicine Federal University of Rio de JaneiroRio de Janeiro 21941-913Brazil Department of Surgery and Anatomy Ribeirão Preto Medical SchoolUniversity of São PauloRibeirao Preto 14049-900São PauloBrazil Department of Internal Medicine São Paulo State University(UNESP)Medical SchoolBotucatu 18618-687São PauloBrazil IBD Unit Federal University of BahiaSalvador 41150-000BahiaBrazil Department of Clinical Medicine Medical SchoolUniversidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Department of Gastroenterology Escola Paulista de MedicinaSão Paulo 04023-900Brazil Hospital de Clinicas Universidade Federal do ParanaCuritiba 80060-900ParanaBrazil Department of Proctology Beneficencia Portuguesa Hospital/Kaiser Day HospitalSao Jose do Rio Preto 15015110São PauloBrazil Department of Gastroenterology and Hepatology Sciences Hospital de ClínicasUniversidade Federal do Rio Grande do SulPorto Alegre 90560002Rio Grande do SulBrazil Department of Gastroenterology Faculdade de Medicina do ABCSanto Andre 09060-870São PauloBrazil Department of General Medicine Gastroenterology UnitUniversity HospitalFederal University of PiauiTeresina 64049-550PiauíBrazil Department of Gastroenterology Faculdade de MedicinaUniversidade Federal de GoiásGoiania 74535-170GoiasBrazil Department of Surgery Botucatu Medical School at São Paulo State University(UNESP)Botucatu 18618687São PauloBrazil Department of Gastroenterology UNIFESPSão Paulo 04040-002Brazil IBD unit Gastroenterology DepartmentHospital Nossa Senhora das GraçasCuritiba 80810-040ParanaBrazil Department of Proctology Kaiser Hospital DiaSao Jose do Rio Preto 15015-110São PauloBrazil Health Sciences Center Epidemiology UnitState University of PiauiTeresina 64001-280PiauíBrazil Department of Gastroenterology CMIP Centro Mineiro de PesquisaJuiz de Fora 36010-570Minas GeraisBrazil Scientific Affairs Takeda Pharmaceuticals BrazilSão Paulo 04709-011Brazil Clinical Research Takeda Pharma

BACKGROUND Understanding the treatment landscape of inflammatory bowel diseases(IBD)is essential for improving disease management and patient *** is the largest Latin American country,and it presents socioeconomic and health care differences across its geographical *** country has the highest increase in IBD incidence and prevalence in Latin America,but information about the clinical and treatment characteristics of IBD is *** To describe the sociodemographic,clinical,and treatment characteristics of IBD outpatients in Brazil overall and in the Southeast,South and Northeast/Midwest *** Multicenter,cross-sectional study with a 3-year retrospective chart review *** with moderate-to-severe Crohn’s disease(CD)or ulcerative colitis(UC)were consecutively enrolled between October 2016 and February *** CD at enrollment was defined as a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or a calprotectin level>200μg/g or an active result based on colonoscopy suggestive of inadequate control during the previous year;active UC was defined as a partial Mayo score≥*** statistics were used to analyze all *** In a total of 407 included patients,CD was more frequent than UC,both overall(264 CD/143 UC patients)and by region(CD:UC ratios of 2.1 in the Southeast,1.6 in the South and 1.2 in the Northeast/Midwest).The majority of patients were female(54.2%of CD;56.6%of UC),and the mean ages were 45.9±13.8 years(CD)and 42.9±13.0 years(UC).The median disease duration was 10.0(range:0.5-45)years for both IBD *** enrollment,44.7%[95%confidence interval(CI):38.7-50.7]of CD patients and 25.2%(95%CI:18.1-32.3)of UC patients presented with active *** than 95%of IBD patients were receiving treatment at enrollment;CD patients were commonly treated with biologics(71.6%)and immunosuppressors(67.4%),and UC patients were commonly treated with mesalazine[5-Aminosalicylic acid(5-ASA)]derivates(69.9%)and

关键词： Inflammatory bowel disease Crohn's disease Ulcerative colitis Disease activity Epidemiology Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Magnetic Resonance Imaging in the Acquired Demyelinating Disorders： A Pediatric Cohort Study

引用

journal of Pharmacy and Pharmacology 2018年第1期6卷 20-31页

作者： Santa Ignez L. j. Silveira de Souza A. Amancio A. P. R. L. Almeida j.V. Gamarano G. M. F. Costa A. A.B.P Tovar-Moll F. saad T. R. D. Fernandes Figueira National Institute of Women Child and Adolescent Health-IFF/FIOCRUZ Rio de Janeiro 22250-020 Brazil D'Or Research and Teach Institute-IDOR Rio de Janeiro 22081-100 Brazil Federal University of Rio de janeiro-UFRj Rio dejaneiro 21941-901 Brazil

Objective： Describing the characteristics of the MRI （magnetic resonance imaging） of patients with ADD （acquired demyelinating disorder） followed in a specialized pediatric clinic. Methods： Descriptive and retrospective study of the MRIs of a pediatric ADD cohort. The included images were acquired in machines with 1.5 or 3T magnets. Low-quality images were excluded. The radiological characteristics of the lesions were described using the 2010 Revised McDonald Diagnostic Criteria regarding localization, contrast enhancement and optic nerve alterations. Results： Twenty-three patients were included （55% female）. The mean age of the first clinical event was 7.7 years. Most common diagnosis was Clinically Isolated Syndrome （35%）, followed by Multiple Sclerosis （30%）, Neuromyelitis Optica （17%） and Acute Disseminated Encephalomyelitis （17%）. Mean time elapsed until diagnosis was 1.8 years. Follow-up MRIs of ADEM patients showed complete or partial resolution of lesions; MS lesions were mostly localized in the brain and four patients had contrast enhancement of lesions in their last available MRI. All NMO （neuromyelitis optica） patients had extensive spinal lesions, and two had optic neuritis. All patients with CIS （clinically isolated syndrome） had focal spinal lesions and evolved with radiologic improvement. Conclusions： ADEM and CIS patients＇ MRIs showed lesion reduction, while MS and NMO patients developed new lesions during follow-up.

关键词： Magnetic resonance imaging multiple sclerosis neuromyelitis optica acute disseminated encephalomyelitis clinically isolated syndrome.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Developing a Low-cost,smart,handheld electromyography biofeedback system for telerehabilitation with Clinical Evaluation

引用

Medicine in Novel Technology and Devices 2021年第2期10卷 17-24页

作者： Mazen M.Yassin Abubakr M.Saber Mohamed N.saad Ashraf M.Said Ayman M.Khalifa Biomedical Engineering Department Minia UniversityMinia61111Egypt Department of Biomedical Engineering Helwan UniversityCairo11731Egypt j.Crayton Pruitt Family Department of Biomedical Engineering University of FloridaGainesvilleFL32611USA

Existing telerehabilitation systems require highly experienced personnel to interpret a patient’s muscle activity in a specialized lab,limiting the biofeedback available at the patient’s *** addition,there is no contact between physiotherapists and patients *** study designed and implemented an interactive teleelectromyography(EMG)biofeedback device for facilitating patients’rehabilitation and giving the physiotherapist the ability to develop and monitor personalized treatment for each patient precisely and *** device comprised a device that acquires EMG signals during muscular activity and two cell phone applications,one for the patient and the other for the physiotherapist;traced muscle activity;and enabled the physiotherapist to monitor and control the patients’sessions through a Google Firebase *** signals were acquired from five subjects,and results were compared to a certified *** evaluation process involved two metrics,correlation coefficient and root mean square value(RMSV).The proposed EMG biofeedback device is an integrated solution with numerous features,such as low cost,handheld size,patient-friendly interface,contributions to rapid healing,and secure *** addition,it provides raw EMG signals for applied research applications.

关键词： Electromyography EMG Biofeedback Physiotherapy Telerehabilitation Home use Rehabilitation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

BOLD-MR成像技术中组织缺氧分数在肾血管疾病中的应用价值

引用

国际医学放射学杂志 2013年第6期 574-574页

作者： A.saad j.Crane j.F.Glockner S.M.S.Herrmann H.Friedman B.Ebrahimi 刘莹莹 Division of Nephrology and Hypertension Mayo Clinic 200 First StRochester MN 55905

摘要目的验证BOLD-MR成像技术中组织缺氧分数、以及肾血流量(RBF)组织灌注和肾小球滤过率(GFR)在评估肾动脉狭窄病人肾组织缺氧方面优于传统局部区域性评估

关键词：组织缺氧 BOLD-MR 应用价值成像技术分数 MR

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Diversity of Botryosphaeriaceae species associated with grapevine and other woody hosts in Italy,Algeria and Tunisia,with descriptions of Lasiodiplodia exigua and Lasiodiplodia mediterranea ***

引用

Fungal Diversity 2015年第2期71卷 201-214页

作者： B.T.Linaldeddu A.Deidda B.Scanu A.Franceschini S.Serra A.Berraf-Tebbal M.Zouaoui Boutiti M.L.Ben jamâa A.j.L.Phillips Dipartimento di Agraria Sezione di Patologia vegetale ed EntomologiaUniversitàdegli Studi di Sassarivia E.De Nicola 107100 SassariItaly Département des Biotechnologies Facultédes Sciences de la Vie et de la TerreUniversitéSaad Dahleb09000 BlidaAlgeria INRGREF Laboratoire de Gestion et de Valorisation des Ressources ForestièresB.P.N 22080 ArianaTunisia Centro de Recursos Microbiológicos Departamento de Ciências da VidaFaculdade de Ciências e TecnologiaUniversidade Nova de Lisboa2829-516 CaparicaPortugal

The diversity of Botryosphaeriaceae species associated with“Botryosphaeria dieback”of grapevine was investigated in 18 vineyards in Sardinia,*** isolates obtained from different woody hosts including holm oak,sweet orange and broom bush in Italy,Algeria and Tunisia were also *** and cultural characteristics as well as ITS and EF1-αsequence data were used to identify the fungal ***-eight botryosphaeriaceous isolates were obtained from 113 symptomatic grapevine samples,from which ten species were *** seriata was the dominant species(25%of isolates),followed by Neofusicoccum parvum(21.7%).Two species,Diplodia olivarum and *** are reported for the first time on *** addition,two new species namely Lasiodiplodia mediterranea *** grapevine,holm oak and sweet orange and Lasiodiplodia exigua *** broom bush are *** artificial inoculation experiments conducted on excised green grapevine shoots and lignified canes as well as holm oak seedlings,*** was shown to be an aggressive pathogen.

关键词： Citrus×sinensis Diplodia Lasiodiplodia Neofusicoccum Quercus ilex Retama raetam

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：