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southern East siberia Pliocene-Quaternary faults:Database,analysis and inference

Geoscience Frontiers 2014年第4期5卷 605-619页

作者： Oksana V.Lunina Riccardo Caputo Anton A.gladkov Andrey s.gladkov Institute of the Earth's Crust Siberian Branch of Russian Academy of Sciences University of Ferrara Department of Physics and Earth SciencesVia Saragat 144122 FerraraItaly

This paper presents the first release of an Informational system（Is）devoted to the systematic collection of all available data relating to Pliocene-Quaternary faults in southern East siberia,their critical analysis and their seismotectonic *** final goal of this project is to form a new base for improving the assessment of seismic hazard and other natural processes associated with crustal *** presented Is has been exploited to create a relational database of active and conditionally active faults in southern East siberia（between 100°-114° E and 50°-57° N）whose central sector is characterized by the highly seismic Baikal rift *** information within the database for each fault segment is organized as distinct but intercorrelated sections（tables,texts and pictures,etc.）and can be easily visualized as HTML pages in offline *** preliminary version of the database distributed free on disk already highlights the general fault pattern showing that the Holocene and historical activity is quite uniform and dominated by NE-sW and nearly E-W trending faults;the former with a prevailing dip-slip normal kinematics,while the latter structures are left-lateral strike-slip and oblique-slip（with different proportion of left-lateral and normal fault slip components）.These faults are mainly concentrated along the borders of the rift basins and are the main sources of moderate-to-strong（M≥5.5）earthquakes on the southern sectors of East siberia in recent *** a whole,based on analyzing the diverse fault kinematics and their variable spatial distribution with respect to the overall pattern of the tectonic structures formed and/or activated during the late Pliocene-Quaternary,we conclude they were generated under a regional stress field mainly characterized by a relatively uniform NW-sE tension,but strongly influenced by the irregular hard boundary of the old siberian *** obtained inferences are in an agreement with the existing models

关键词： Pliocene-Quaternary faults Database seismic hazard Tectonics southern East siberia

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Thermodynamic and rate variational formulation of models for inhomogeneous gradient materials with microstructure and application to phase field modeling

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Acta Mechanica sinica 2015年第2期31卷 162-172页

作者： s.yatos.av gladkov Bob svendsen Material Mechanics RWTH Aachen Aachen Germany Microstructure Physics and Alloy Design Max-Planck-Institut fur Eisenforschung DusseldorfGermany

In this work,thermodynamic models for the energetics and kinetics of inhomogeneous gradient materials with microstructure are formulated in the context of continuum thermodynamics and material *** simplicity,attention is restricted to isothermal *** materials of interest here are characterized by（1） first- and secondorder gradients of the deformation field and（2） a kinematic microstructure field and its gradient（e.g.,in the sense of director,micromorphic or Cosserat microstructure）.Material inhomogeneity takes the form of multiple phases and chemical constituents,modeled here with the help of corresponding phase *** requirements together with the dissipation principle result in the reduced model field and constitutive *** cases of these include the wellknown Cahn-Hilliard and Ginzburg-Landau *** the last part of the work,initial boundary value problems for this class of materials are formulated with the help of rate variational methods.

关键词： Continuum thermodynamics Material inhomogeneity Conservative Non-conservative phase fields

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Biobased polyurethanes for biomedical applications

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Bioactive Materials 2021年第4期6卷 1083-1106页

作者： sophie Wendels Luc av´erous BioTeam/ICPEEs-ECPM UMR CNRS 7515Universit´e de Strasbourg25 Rue Becquerel67087Strasbourg Cedex 2France

Polyurethanes(PUs)are a major family of polymers displaying a wide spectrum of physico-chemical,mechanical and structural properties for a large range of *** have shown suitable for biomedical applications and are used in this domain since *** current variety of biomass available has extended the diversity of starting materials for the elaboration of new biobased macromolecular architectures,allowing the development of biobased PUs with advanced properties such as controlled biotic and abiotic *** this frame,new tunable biomedical devices have been successfully *** structures with precise tissue biomimicking can be obtained and are adequate for adhesion,proliferation and differentiation of many cell’s ***,new smart shape-memory PUs with adjustable shape-recovery properties have demonstrated promising results for biomedical applications such as wound *** fossil-based starting materials substitution for biomedical implants is slowly improving,nonetheless better renewable contents need to be achieved for most PUs to obtain biobased *** a presentation of some PU generalities and an understanding of a biomaterial structure-biocompatibility relationship,recent developments of biobased PUs for non-implantable devices as well as short-and long-term implants are described in detail in this review and compared to more conventional PU structures.

关键词： Polyurethanes Biobased Biomedical Bioactive Tissue engineering Biocompatibility scaffold

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Crystallodiagnostics of some animals' helmintosis

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Asian Pacific Journal of Tropical Medicine 2010年第3期3卷 176-179页

作者： Andrew Martusevich Grishina AA Bochkareva av Laboratory of Physical and Chemical Medicine Institute of Traumatology and Orthopedics

Objective:To investigate the teziocrystalloscopic features of urine which were collected from both healthy rodents and those with ***:Physical-chemical characteristics of urine samples that were collected from 15 mice and 20 rats were estimated by their ability to *** test results were interpreted with integrated identity table which includes 5 main classes of the crystalline and amorphous *** quantitative and semiquantitative evaluation indicators were also ***:Presence of Trichinella spiralis in animal organism transformed results of the biofluid free *** main components of rats’ urine facia were single-crystalline rectangles which were made of cholesterol and its *** biofluid microsamples of healthy rats and rats with echinococcosis had both common and ***:Urine teziocrystalloscopic analysis is an informative method for diagnosis of helminthiasis in animals.

关键词： Biocrystallomics Trichinosis Echinococcosis Crystallodiagnostics Urine

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A case report on disseminated tuberculosis in the setting of coronavirus disease 2019:cause or consequence?

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Emergency and Critical Care Medicine 2022年第3期2卷 175-178页

作者： Himsikhar Khataniar Diya sunil Lalitha av st.Johns Medical College and Hospital BengaluruKarnatakaIndia

Tuberculosis(TB)is a deadly infection that can lead to disseminated disease in children<15years of age exhibiting risk factors such as low host immunity,concurrent infection(s),and/or malnutrition.A case involving a 1... 详细信息

Tuberculosis(TB)is a deadly infection that can lead to disseminated disease in childrens of age exhibiting risk factors such as low host immunity,concurrent infection(s),and/or malnutrition.A case involving a 14-year-old boy diagnosed with disseminated tuberculosis is *** investigation,the patient was positive for coronavirus disease 2019(COVID-19)antibodies,GeneXpert(Cepheid,sunnyvale,CA)positive for TB with multisystem involvement,lymphopenia,and highly elevated inflammatory markers,indicating multisystem inflammatory syndrome in children(MIs-C)and disseminated *** patient was started on antitubercular treatment(ATT),steroids,and supportive *** condition improved over the ensuing few days,and he was discharged with ATT and *** a few studies involving adults have established a connection between the progression of TB and COVID-19,this case report establishes a similar clinical picture in a child,which has not yet been reported.

关键词： Case report COVID-19 Disseminated tuberculosis steroids Tuberculosis

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Treatment of children with neurogenic bladder dysfunctions using dynamic nero-electrostimulation(DENs) and M-Cholinolytic therapy

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中国现代医学杂志 2013年第2期23卷 13-16页

作者： Zubarenko av stoeva NV Godlevska TL Department of Pediatrics Odessa National Medical University(rector-academic of NAMS in UkraineProfessor Zaporozhan V.N.)Valikhovsky lane 2Kyiv 65082Ukraine

【Objective】 To investigate effects of combined usage of dynamic neuro-electric stimulation(DNEs) and M-cholynolytic therapy(oxybutynin) upon manifestations of neurogenic bladder dysfunctions(NBD) in children.【Method】 Urodynamics examination included registration of extemporaneous urinary excretion,urofluometry,and retrograde cytometry in horizontal and vertical position by example of urodynamic system(UDs) ACs 180 Plus(MENFIs BioMed.,UsA).In accordance to severity of clinician manifestations,three groups of patients have been defined(27-highest one,49-middle and 51 low levels).Dynamic neuro-electrostimulation(DNEs) procedures were conducted using the"DiaDNEs-PKM"device(Russian Federation).The children were exposed to juxtaspinal stimulation on s1-s3 level-altogether 10 sessions have been ***(driptan) was used in dosage of 2.5 mg per diem.【Result】It was established that combined usage of DNEs and oxybutynin in the group with highest severity caused the reduction of manifestations by 3.1 times while separately given DNEs and basic therapy were followed by 34.1% and 28.0% reduction ***,DNEs and oxybutynin reduced severity in patients with pronounced disturbances by 7.5 *** usage of oxybutynin and DNEs in severely manifested NBD increased the effective volume of bladder by 2.3 *** significant reduction of both intrabladder pressure(by 48.0%) and compliance of the bladder(by 4.8 times) were detected under condition of combined usage of DNEs and *** mentioned indices were modified to less extent in case of separate usage of DNEs or oxybutynin when compared with the one registered after the combined their usage(P sion】Combined usage of DENs and oxybutinin(driptan) is effective in most severe cases in children suffered from neurogenic overactive bladder.

关键词：医学临床诊断疾病

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safety evaluation of Eugenia jambolana seed extract

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Asian Pacific Journal of Tropical Medicine 2010年第12期3卷 982-987页

作者： Jayanta M sankhari Ravirajsinh NJadeja Menaka C Thounaojam Ranjitsinh V Devkar Raniachandran av Division of Phytotherapeutics and Metabolic Endocrinology Department of ZoologyFaculty of ScienceThe MS University of BarodaVadodara-390002GujaratIndia

Objective:To evaluate the safety of ethanolic seed extract of Eugenia jambolana（EJsE） using acute and sub-chronic toxicity assays in swiss albino mice as per Organisation for Economic Co-operation and Development（OECD） ***:Possible behavioral changes and lethality were observed in mice administered a single dose[1 000,2 000,3 000,4 000 or 5 000mg/kg body weight（BW）]of EJsE,Plasma levels of metabolic,hepatic,cardiac and renal function markers, electrolytes,blood count and histopathology of major organs were monitored in mice chronically treated with EJsE（1 000,2 000 or 3 000 mg/kg BW） for 28 ***:since no mortality was recorded in the acute toxicity evaluation up to a dose of 5 000 mg/kg bodyweight of EJsE,50% lethal dose(LDsub>50sub>) was assumed to be >5 000 mg/kg *** the sub-chronic toxicity evaluation, no adverse observations were recorded in mice administered with 2 000 mg/kg BW of EJsE; however at 3 000 mg/kg BW dose,moderately significant increase in the plasma levels of urea and creatinine was ***,the lowest observable adverse effect level（LOAEL） for EJsE was found to be 3 000 mg/kg BW and the no observable adverse effect level（NOAEL） was adjudged as 2 000 mg/kg ***:It can be concluded from this study that,orally administered EJsE is safe up to a10 fold higher dose than its reported therapeutic dose.

关键词： Acute toxicity sub chronic toxicity Eugenia jambolana NOAEL LOAEL

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Traditional uses,phytochemistry and pharmacology of Clerodendron glandulosum Coleb - a review

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Asian Pacific Journal of Tropical Medicine 2012年第1期5卷 1-6页

作者： Ravirajsinh N Jadeja Menaka C Thounaojam Thouchom Brojendro singh Ranjitsinh V Devkar av Ramachandran Division of Phytotherapeutics and Metabolic Endocrinology Department of ZoologyFaculty of ScienceThe MS University of BarodaVadodara-390002GujaratIndia Department of Chemistry Oriental CollegeImphal-795001ManipurIndia

Present review for the first time provides a complete botanical description and information on ethnomcdicinal uses of Clerodendron ***(CG:***).Recent studies conducted from our laborator) provide pharmacological evidence for its anti-hypertensive,antidiabetic and anti-obesity ***,its beneficial potential in preventing in vitro and in vivo non-alcoholic steatohepatitis and atherosclerosis and potent hcpatoprotective and free radical scavenging abilities along with its acute and sub- chronic toxicologiesl evaluations are also reported from our *** keeping with its traditional uses,CG extract was capable of ameliorating experimentally induced hypertension,diabetes and *** beneficial potential against NAsH induced oxidative stress and atherosclerosis can be attributed to its potent free radical scavenging ***—toxic nature of CG leaf extract further provides added merit to its reported pharmacological *** present review summarizes the pioneering scientific evidence for the pharmacological effects of CG against related metabolic disorders like hypertension,diabetes and obesity along with anti oxidant potential and beneficial elicits against non alcoholic steatohepatitis.

关键词： Clerodendron glandulosum.Coleb Hypertension Hyperlipidemia Insulin resistance Obesity Atherosclerosis

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青少年和青年肿瘤患者的化疗：远期副作用的管理

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英国医学杂志中文版 2017年第1期20卷 42-50页

作者： saif s Ahmad Marika av Reinius Helen M Hatcher Thankamma VAjithkumar 黎立喜马飞 Department of Oncology Addenbrooke's Hospital Cambridge University Hospitals NHS Foundation Trust MRC Cancer Unit University of Cambridge Cambridge Biomedical Campus 中国医学科学院肿瘤医院

癌症是西方国家青少年和青年中与疾病相关死亡的主要原因。在英国，癌症分别占青少年和青年中男性和女性死亡人数的9％和15％，并且从20世纪90年代中期以来，癌症发病率上升了19％，从2011年至2013年平均每年新增2300例癌症患者。在日... 详细信息

癌症是西方国家青少年和青年中与疾病相关死亡的主要原因。在英国，癌症分别占青少年和青年中男性和女性死亡人数的9％和15％，并且从20世纪90年代中期以来，癌症发病率上升了19％，从2011年至2013年平均每年新增2300例癌症患者。在日本，从2000年至2006年，因癌症死亡的人数达到近7000人。

关键词：青少年肿瘤患者化疗

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用土层有效贮水量来规范农作物的灌溉

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华中农业大学学报 2000年第3期19卷 249-251页

作者： Zaly.,sV Krav.,av 俄罗斯萨拉托夫州立农业大学林业与土壤改良研究所

用土壤的农业水文学特性。如土壤质地、土壤容量、最低田间含水量和萎蔫下的土壤含水量对作物灌溉的规范化进行了研究。结果发现，如果考虑作物的灌溉制度，同有效贮水量决定的土层中的灌溉前含水量为一常数，即在有效植物生长期之间，... 详细信息

用土壤的农业水文学特性。如土壤质地、土壤容量、最低田间含水量和萎蔫下的土壤含水量对作物灌溉的规范化进行了研究。结果发现，如果考虑作物的灌溉制度，同有效贮水量决定的土层中的灌溉前含水量为一常数，即在有效植物生长期之间，土层中的灌溉前含水量的５０％，而有有效生长期则为７０％。土层有效贮水量为决定不同土壤灌溉前含水量的一个概略性指标。

关键词：灌溉土壤水份土层有效贮水量

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