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Contribution of High sensible C-Reactive Protein (hsCRP) in the Assessment of the Risk of Onset of Type 2 Diabetes and Its Cardiovascular Complications

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Journal of Diabetes Mellitus 2024年第2期14卷 95-107页

作者： Maïmouna Touré Léopold Ngor sène Jean Pierre Diagne Demba.Diédhiou souleymane Thiam Abdou Khadir sow Mor Diaw Aïssatou seck salimata Diagne Houndjo Abdoulaye ba.Abdoulaye samb Fatou Diallo-Agne Modou Oumy Kane Laboratoire de Physiologie et d’ Explorations Fonctionnelles Physiologiques Facult&#233 de M&#233decine de Pharmacie et d&#8217OdontoStomatologie (FMPOS) Universit&#233 Cheikh Anta Diop (UCAD) Dakar S&#233n&#233gal IRL3189 &#8220Environnement Sant&#233 Soci&#233t&#233&#8221 CNRS CNRST Bamako-UCAD Facult&#233 de M&#233decine de Pharmacie et d&#8217OdontoStomatologie (FMPOS) Universit&#233 Cheikh Anta Diop (UCAD) Dakar S&#233n&#233gal Laboratoire Privé de Biologie General Kaolack S&#233n&#233gal Centre Hospitalier universitaire (CHu) Aba.se Ndao Universit&#233 Cheikh Anta Diop (UCAD) Dakar S&#233n&#233gal Laboratoire de Biochimie et de Biologie molé culaire Facult&#233 de M&#233decine de Pharmacie et d&#8217OdontoStomatologie (FMPOS) Universit&#233 Cheikh Anta Diop (UCAD) Dakar S&#233n&#233gal Laboratoire de Physiologie Pharmaceutique Facult&#233 de M&#233decine de Pharmacie et d'OdontoStomatologie (FMPOS) Universit&#233 Cheikh Anta Diop (UCAD) Dakar S&#233n&#233gal

ba.kground: Type 2 diabetes is a metabolic disease characterized by chronic hyperglycemia. The latter plays an essential role in inflammation by stimulating the production of pro-inflammatory cytokines or by increasing their secretion by an oxidative mechanism. These cytokines control the hepatic synthesis of an inflammatory protein called C-Reactive Protein (CRP). High or average values of CRP would have a predictive value of cardiovascular diseases and type 2 diabetes. The relationship between low CRP values and the risk of developing type 2 diabetes and its cardiovascular complications is not sufficiently studied. The hsCRP could serve as a predictive biomarker of risk of onset, follow-up and prognosis for type 2 diabetes and its cardiovascular complications. To answer this problem, we conducted this study, the aim of which was to study the predictive role of hsCRP in the risk of occurrence of type 2 diabetes and its cardiovascular complications. Materials and Methods: This is a prospective and cross-sectional case-control study involving 200 participants including 100 control women and 100 women with type 2 diabetes (mean age was respectively 49.89 years ± 8.26 & 51.92 years ± 7.18;p = 0.066). The interviews were conducted on the ba.is of a questionnaire. Physical examination collected biometric data and cardiovascular constants. The biochemical parameters such as hsCRP were analyzed by an automated Abbott device. Results: We noted that hsCRP was significantly higher in type 2 diabetic subjects compared to control subjects (p (rho = 0.40, p systolic blood pressure (rho = 0.30, p = 0.003), diastolic blood pressure (rho = 0.28, p = 0.006), total body fat (rho = 0.48, p Conclusion: hsCRP has a prognostic value in the evaluation of cardiovascular risk. It seems to play an important role in the pathogenesis of type 2 diabetes mellitus and its cardiovascular complications. It could thus be considered as a biomarker for the screening, monitoring and prognosis of type 2

关键词： hsCRP Biomarker Inflammation Type 2 Diabetes

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新时代国家粮食安全的理论构建与治理进路

中国农村经济 2024年第2期 2-19页

作者：钟钰巴雪真陈萌山中国农业科学院农业经济与发展研究所中国农业科学院

党的十八大以来,习近平关于粮食安全的重要论述,系统阐述和回应了新时代粮食安全的重大理论与实践问题。本文在阐释新时代粮食安全总目标、总要求、总任务、总方针、总路径的基础上,揭示其蕴含的理论逻辑、历史逻辑和实践逻辑。沿着“产... 详细信息

党的十八大以来,习近平关于粮食安全的重要论述,系统阐述和回应了新时代粮食安全的重大理论与实践问题。本文在阐释新时代粮食安全总目标、总要求、总任务、总方针、总路径的基础上,揭示其蕴含的理论逻辑、历史逻辑和实践逻辑。沿着“产品-商品-特殊商品”的理论逻辑,明晰粮食的属性和战略价值;回顾“地方分化-资源匹配-治理转变”的历史逻辑,厘清粮食安全政策体系建立轨迹;围绕“工业化技术化之路、要素集聚之路、县域之路、产业之路、保障之路”的实践逻辑,明确维护粮食安全的发展路径。走好中国特色粮食安全治理之路,应坚持主体论、“两藏”论和自主论,从充分调动地方抓粮和农民种粮“两个积极性”、深入实施“两藏”战略、统筹利用国内国际“两种资源”方面发力。

关键词：粮食安全粮食安全理论粮食安全治理

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数据要素市场体系建构与价值实现路径探索

情报学报 2024年第1期43卷 1-9页

作者：孙建军巴志超夏义堃南京大学数据智能与交叉创新实验室南京210023 南京大学信息管理学院南京210023 南京大学数据管理创新研究中心苏州215163

数据要素市场体系的顶层设计是加快推进数字要素市场化配置、推动我国数字经济高质量发展的前提基础与关键部署。通过剖析当前全国数据要素统一大市场建设面临的瓶颈与挑战,本文分析数据要素市场建设的特殊性,提出全国统一数据要素市场... 详细信息

数据要素市场体系的顶层设计是加快推进数字要素市场化配置、推动我国数字经济高质量发展的前提基础与关键部署。通过剖析当前全国数据要素统一大市场建设面临的瓶颈与挑战,本文分析数据要素市场建设的特殊性,提出全国统一数据要素市场体系“一体两翼”“三基”“七要点”的总体架构思路,以及战略布局、结构布局和空间布局相统一的总体布局方案,并从市场体系建设新特征、内在结构与运行模式解析、数据要素市场与传统要素市场一体化联动机理揭示与场景应用示范等方面探索促进数据要素市场价值升级与高质量发展的实现路径,从而为推动数据资源化、资产化和资本化的可持续运营提供参考借鉴。

关键词：数据要素市场体系架构价值实现路径运行模式联动机制

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高寒草甸斑块化空间分异性及其地形因子影响

草地学报 2024年第2期32卷 570-578页

作者：王祎明李国荣李希来把熠晨王克钰姚文治张静青海大学地质工程系青海西宁810016 青海大学农牧学院青海西宁810016

青藏高原高寒草甸在国家生态环境保护战略中占据重要位置,近几十年来,气候变化和人为因素导致大面积高寒草甸发生斑块化退化。为探究高寒草甸斑块化空间分异性及各斑块类型间(裸地斑块、短期恢复斑块和长期恢复斑块)的分布规律以及其地... 详细信息

青藏高原高寒草甸在国家生态环境保护战略中占据重要位置,近几十年来,气候变化和人为因素导致大面积高寒草甸发生斑块化退化。为探究高寒草甸斑块化空间分异性及各斑块类型间(裸地斑块、短期恢复斑块和长期恢复斑块)的分布规律以及其地形因子的影响,本研究通过3s(Rs,GIs,GNss)技术获取位于青海省河南县和玛多县4个典型研究区的斑块类型分布及地形因子数据,利用景观生态指数探究不同斑块的空间分布差异。结果表明,研究区植被覆盖度随着海拔升高呈现先增加后减小的趋势,斑块景观的破碎化程度呈现先减小后增大的趋势。不同海拔地区斑块化程度最高的斑块类型都是长期恢复斑块。地形因子显著影响着不同斑块的分布,长期恢复斑块和健康草甸主要分布在阳坡平缓区域。

关键词：斑块化植被覆盖度景观格局地形因子空间差异

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我国制造业外循环国际环境问题研究

税务与经济 2024年第2期 59-67页

作者：巴殿君刘力源吉林大学东北亚学院吉林长春130012

自2010年以来,中国成为世界公认的“世界工厂”,制造业也成为我国经济社会发展的重要支柱。当前,世界科技变革正在不断加速,而逆全球化趋势加剧、世界经济复苏进程缓慢、局部冲突愈演愈烈等问题,使得世界进入了一个快速运动和革命的新... 详细信息

自2010年以来,中国成为世界公认的“世界工厂”,制造业也成为我国经济社会发展的重要支柱。当前,世界科技变革正在不断加速,而逆全球化趋势加剧、世界经济复苏进程缓慢、局部冲突愈演愈烈等问题,使得世界进入了一个快速运动和革命的新时期。中国正处于发展的战略机遇期、风险期和挑战期,面对个别外国政府对中国企业的围剿逐步升级,我国依然要坚定对外开放的态度,完善外循环服务内循环的经济发展理念,借力RECP建立供应链外循环平衡发展新模式,抓住机遇加强对制造业供应链的风险预测,利用数字经济消除制造业供应链外循环阻点,从而有效提升我国制造业在国际市场上的竞争能力,进一步优化发展制造业。

关键词：制造业外循环国际环境供应链

商品有机肥对不同坡向退化高寒草甸土壤特性的影响

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草地学报 2024年第8期32卷 2638-2647页

作者：徐文印马昀峤柴瑜段成伟把熠晨张静李希来青海大学农牧学院青海西宁810016 嘉峪关市林业和草原局甘肃嘉峪关735100

为研究有机肥施用量对黄河源区斑块化退化高寒草甸土壤特征的影响,我们在青海省河南蒙古族自治县多松乡阳坡和阴坡样地的斑块化退化高寒草甸,分别设置0 g·m^(-2)(CK),150 g·m^(-2)(M 1),450 g·m^(-2)(M 2),750 g·m^(-2)(M 3),1050 g... 详细信息

为研究有机肥施用量对黄河源区斑块化退化高寒草甸土壤特征的影响,我们在青海省河南蒙古族自治县多松乡阳坡和阴坡样地的斑块化退化高寒草甸,分别设置0 g·m^(-2)(CK),150 g·m^(-2)(M 1),450 g·m^(-2)(M 2),750 g·m^(-2)(M 3),1050 g·m^(-2)(M 4),1350 g·m^(-2)(M 5)6个商品有机肥施用量梯度,测定土壤养分、微生物生物量、酶活性以及微生物多样性的变化特征。结果显示:阳坡退化高寒草甸土壤呈弱碱性,有机肥不同处理下的土壤理化性质无显著变化。阴坡退化高寒草甸土壤pH值呈中性,土壤有机碳、土壤全氮和土壤全磷含量M 4处理较CK处理显著提高。在试验样地中土壤微生物生物量碳、氮、磷含量在有机肥不同施用量下无显著变化。阳坡样地土壤β-1,4-葡萄糖苷酶在M 5处理下达到最大值。通过灰色关联度综合分析得出在阳坡样地最佳商品有机肥施用量为450 g·m^(-2),阴坡样地有机肥最佳施用量为1050 g·m^(-2),该用量在恢复斑块化退化高寒草甸土壤理化性质、酶活性和微生物多样性方面具有明显的效果。

关键词：有机肥高寒草甸土壤理化性质土壤微生物生物量土壤酶活性微生物多样性灰色关联度

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基于GPu的北斗B1宽带复合信号实时发生器设计

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系统工程与电子技术 2024年第3期46卷 795-804页

作者：王子涵巴晓辉姜维蔡伯根王剑文韬北京交通大学电子信息工程学院北京100044 北京交通大学轨道交通控制与安全国家重点实验室北京100044 北京市电磁兼容与卫星导航工程技术研究中心北京100044 北京交通大学计算机与信息技术学院北京100044

为了实现北斗B1C+B1I信号的联合生成,提出一种基于软件无线电和图形处理器(graphics processing unit,GPu)加速的北斗B1宽带复合信号的实时生成方法,该方法针对单边带复数二进制偏移载波(single-sideba.d complex binary offset carrier... 详细信息

为了实现北斗B1C+B1I信号的联合生成,提出一种基于软件无线电和图形处理器(graphics processing unit,GPu)加速的北斗B1宽带复合信号的实时生成方法,该方法针对单边带复数二进制偏移载波(single-sideba.d complex binary offset carrier,sCBOC)调制方式的信号体制进行设计,系统根据用户配置的接收机运动轨迹和星历文件,生成中频信号并通过射频端发射。为了进一步提升GPu并行运算速度,从优化设备内存结构、设计并行线程架构和统一计算设备架构流(compute unified device architecture stream,CuDA)加速3个方面,设计了基于异步运算的加速采样点数据计算的CuDA优化实现方案。测试结果证明,优化后的算法可以基于sCBOC调制实时生成北斗B1I+B1C信号,基于GTX3060的GPu平台,信号90 M采样率下能实现8颗卫星复合信号的实时生成。

关键词： B1宽带复合信号软件无线电单边带复数二进制偏移载波调制统一计算设备架构流实时生成

Estimation of the Direct Cost of Management of Venous Thromboembolism in Three Reference Hospitals in the City of Yaoundé: A Retrospective study over a Three-Year Period

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World Journal of Cardiovascular Diseases 2024年第2期14卷 99-114页

作者： Hamadou ba.Nganou-Ngnindjio Chris Nadège Tatchim samuel Aimé Kamdem Félicité Tchoukoua serge Honoré Ahmadou jingi Danwe Dieudonne Kingue samuel Faculty of Medicine and Biomedical sciences University of Yaoundé I Yaoundé Cameroon Department of Internal Medicine Garoua General Hospital Garoua Cameroon Cardiology Department Yaoundé Central Hospital Yaoundé Cameroon Higher Institute of Health sciences University of the Mountains Bagangté Cameroon Faculty of Medicine and Pharmaceutical sciences University of Douala Douala Cameroon Department of Internal Medicine Douala General Hospital Douala Cameroon Faculty of Health sciences University of Bamenda Bamenda Cameroon Cardiology Department Yaoundé General Hospital Yaoundé Cameroon

ba.kground: Venous thromboembolism (VTE) is a major public health problem due to its increasing frequency, mortality and management cost. This cost may require major financial efforts from patients, especially in developing countries like ours where less than 7% of the population has health insurance. This study aimed to estimate the direct cost of managing VTE in three reference hospitals in Yaoundé. Methods: This was a cross-sectional retrospective study over a three-year period (from January 1st 2018 to December 31 2020) carried out in the Cardiology departments of the Central and General Hospitals, and the Emergency Centre of the city of Yaoundé. All patients managed during the study period for deep vein thrombosis and pulmonary embolism confirmed by venous ultrasound coupled with Doppler and computed tomography pulmonary angiography respectively were included. For each patient, we collected sociodemographic and clinical data as well as data on the cost of consultation, hospital stay, workups and medications. These data were analysed using sPss version 23.0. Results: A total of 92 patient’s records were analysed. The median age was 60 years [48 - 68] with a sex ratio of 0.53. The median direct cost of management of venous thromboembolism was 766,375 CFAF [536,455 - 1,029,745] or $1415 usD. Management of pulmonary embolism associated with deep vein thrombosis was more costly than isolated pulmonary embolism or deep vein thrombosis. Factors influencing the direct cost of management of venous thromboembolism were: hospital structure (p = 0.015), health insurance (p 0.001), type of pulmonary embolism (p = 0.021), and length of hospital stay (p = 0.001). Conclusion: Management of VTE is a major financial burden for our patients and this burden is influenced by the hospital structure, health insurance, type of pulmonary embolism and length of hospital stay.

关键词： Cost Management Venous Thromboembolism Yaoundé

Improving the Quality of ba.ba. Oil by Filtration on Activated Carbon from the Fruit Capsules

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Journal of Materials science and Chemical Engineering 2024年第1期12卷 69-83页

作者： Edouard Mba.ick Ndiaye Alioune sow Papa Guédel Faye Kalidou ba.Mouhamed Ndoye Omar Ibn Khatab Cisse Nicolas Cyrille Ayessou Mady Cisse Laboratory of Water Energy Environment and Industrial Processes (LE3PI) ESP-UCAD Dakar Senegal Laboratoire of Biological Agronomic Food Sciences and Modeling of Complex Systems (LABAAM) UFR of Agronomic Sciences Aquaculture and Food Technologies (S2ATA) Gaston Berger University of Saint-Louis Saint-Louis Senegal National school of Agriculture University Iba Der Thiam of Thiès Thiès Senegal Center of studies on Food security and Functional Molecules (CEsAM-REsCIF) ESP-UCAD Dakar Senegal

The ba.ba., Adansonia digitata L., plays an important role in the economy of local populations. Nowadays, ba.ba. seed oil is highly prized for its many cosmetic and therapeutic applications, and for its composition of unsaturated fatty acids, sterols, and tocopherols. However, it undergoes numerous reactions during production, processing, transport, and storage, leading to undesirable products that make it unstable. The aim of this study was to provide local processors with innovative solutions for the treatment of unrefined vegetable oils. To this end, an experimental device for filtering crude oil on activated carbon made from fruit capsules was designed. The results obtained after the treatment show a significant decrease at (p ue (1.62 to 0.58 mg KOH/g), peroxide value (4.40a to 0.50c mEqOsub>2sub>/Kg), chlorophyll concentration (1.81 to 0.50 mg/Kg) and primary and secondary oxidation products. According to these results, activated carbon’s adsorptive power eliminates oxidation products and certain pro-oxidants such as chlorophyll, resulting in a cleaner, more stable and better storable oil.

关键词： Activated Carbon Adansonia digitata L. ba.ba. Fruit ba.ba. Oil stability