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Discovery and identification of clay-sized tuffaceous rocks in Chang 7 Member of upper Triassic Yanchang Formation in Ordos Basin,China

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Journal of Central s.uth university 2020年第6期27卷 1814-1827页

作者： ZHENG Qing-hua liu Xing-jun liu Yi-qun ZHOu Ding-wu YOu Ji-yuan YANG Kai-yan school of Chemistry&Chemical Engineering Yulin UniversityYulin 719000China Changqing Division China Petroleum Well Logging Limited CompanyXi’an 710201China Department of Geology Northwest UniversityXi’an 710069China College of Earth science and Engineering Shandong University of Science and TechnologyQingdao 266510China Fengcheng Field Operation District PetroChina Xinjiang Oilfield CompanyKaramay 834000China

This s.udy for the first time demonstrates that some of the so-called clay-sized mudstones observed by the naked eye,such as clay-sized black mudstones and clay-sized oil shales,which are rich in black organic matter(including oil and asphaltene),in the Chang 73 submember of the upper Triassic Yanchang Formation in the Ordos Basin of China are actually clay-sized tuffaceous rocks(including tuff,sedimentary tuff and tuffaceous sedimentary rock)with high hydrocarbon generation ***,these rocks can be defined as clay-sized tuffaceous s.urce *** of this lithology has important theoretical and practical significance for the exploration and development of shale oil in the Chang 7 *** the macroscopic observation of drill cores and outcrop profiles,microscopic observation of electron probe thin sections and whole-rock inorganic geochemical analysis(including major,trace and rare earth elements),this work demonstrates that the organic matter-rich clay-sized tuffaceous rocks,especially clay-sized tuffs,have the following ***,the clay-sized tuffaceous rocks with little black organic matter are mainly greyish white,yellowish brown and purplish grey,and mixed colors occur in areas with strong bentonite ***,the clay-sized tuffaceous rocks have experienced strong devitrification and recrystallization,forming abundant flaky aluminosilicate minerals with directional *** thin sections.under a polarizing microscope,the interference colors generally show regular alternation between the lowest interference color of first-order yellow and the highest interference color of second-order ***,the rock samples plot in the igneous rock field in the TiO2-siO2 cross-plot and exhibit similar trace element and rare earth element patterns on spider diagrams,indicating that the samples are derived from the same *** results prove that clay-sized tuffaceous rocks may be widespread in the Chang 73 s

关键词： Ordos Basin Chang 7 Member clay-sized mudstone clay-sized tuffaceous rock lithologic identification

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临床医生职业倦怠现状及相关因素研究

第三军医大学学报 2020年第3期42卷 288-293页

作者：刘媛刘国祥陆军军医大学(第三军医大学)

目的探讨临床医生职业倦怠现状与影响机制。方法向重庆3所三甲综合医院医生发放医患关系量表、医生职业认同量表和职业倦怠量表,有效回收529份,采用结构方程建模的方法分析变量间的关系。结果①不同性别、年龄、科室、每周工作时长分组... 详细信息

目的探讨临床医生职业倦怠现状与影响机制。方法向重庆3所三甲综合医院医生发放医患关系量表、医生职业认同量表和职业倦怠量表,有效回收529份,采用结构方程建模的方法分析变量间的关系。结果①不同性别、年龄、科室、每周工作时长分组的医生在情感衰竭、去人性化、低成就感上的差异有统计学意义(PsEA=0.08,NFI=0.92,CFI=0.94,χ^2/df=4.37)。结论职业认同是医患关系与情感衰竭、去人格化的部分中介变量,是医患关系与低成就感的完全中介变量,医患关系是职业认同影响低成就感的根本来源。

关键词：医患关系职业认同职业倦怠结构方程模型

Bilayer twisting as a mean to isolate connected flat bands in a kagome lattice through Wigner crystallization

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Chinese Physics B 2021年第7期30卷 5-10页

作者： Jing Wu Yue-E Xie Ming-Xing Chen Jia-Ren yuan Xiao-Hong Yan sheng-Bai Zhang yuan-Ping Chen school of Physics and Optoelectronics Xiangtan UniversityXiangtan 411105China Faculty of science Jiangsu UniversityZhenjiang 212013China school of Physics and Electronics Hunan Normal UniversityChangsha 410081China Department of Physics Applied Physicsand Astronomy Rensselaer Polytechnic InstituteTroyNew York 12180USA

The physics of flat band is novel and rich but difficult to *** this regard,recently twisting of bilayer van der Waals(vd W)-bounded two-dimensional(2 D)materials has attracted much attention,because the reduction of Brillouin zone will eventually lead to a diminishing kinetic ***,one may start with a 2 D kagome lattice,which already possesses flat bands at the Fermi level,but unfortunately these bands connect quadratically to other(dispersive)bands,leading to undesirable ***,we propose,by first-principles calculation and tight-binding modeling,that the same bilayer twisting approach can be used to isolate the kagome flat *** the starting kinetic energy is already vanishingly small,the interlayer vd W potential is always sufficiently large irrespective of the twisting *** such the electronic states in the(connected)flat bands become unstable against a spontaneous Wigner crystallization,which is expected to have interesting interplays with other flat-band phenomena such as novel superconductivity and anomalous quantum Hall effect.

关键词： twisted bilayer kagome graphene flat bands Wigner crystallization

small Interfering RNA Targeting α-Fodrin suppressing the Immune Response of sjogren's syndrome Mice

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Chinese Medical Journal 2018年第22期131卷 2752-2754页

作者： Xiao-Lin sun Chun-Yan Pang yuan liu Wei Zhang Yong-Fu Wang Department of Rheumatology The First Affiliated Hospital of Baotou Medical CollegeBaotouInner Mongolia 014010China

To the Editor:sjogren's syndrome (ss)is a multisystem chronic autoimmune disease,and mainly affects the lacrimal and salivary glands,leading to ocular and oral *** is characterized by a large quantity of autoantibodies and involves multiple systems including the lymphatic system,blood,lungs,kidneys, liver,muscles,and *** complications include interstitial pulmonary fibrosis,peripheral neuropathy,tracheobronchial sicca, blindness,arthralgia,oral candidiasis,and *** main histopathological feature of ss is lymphocytic infiltration of the exocrine glands,resulting in acinar cell death,probably through apoptosis.[1]The exact etiology and pathogenesis of ss are still not clear.

关键词： RNA α-Fodrin

Effects of GsTM1/GsTT1 gene polymorphism and fruit & vegetable consumption on antioxidant biomarkers and cognitive function in the elderly: a community based cross-sectional s.udy

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Effects of GSTM1/GSTT1 gene polymorphism and fruit & vegetab...

Exosomal PD-L1 induces osteogenic differentiation and promotes fracture healing by acting as an immunosuppressant

第十二届全国营养科学大会

作者： yuan Linhong liu Jinmeng Ma Weiei liu Quanri Xiao Rong 首都医科大学

Objectives It was reported that Glutathione s-transferase(GsT)gene polymorphism and fruit and vegetable(FV)intake were associated with body antioxidant *** oxidative/anti-oxidative imbalance played an important role i...

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Bioactive Materials 2022年第7期7卷 300-311页

作者： Ze Lin yuan Xiong Weilin Meng Yiqiang Hu Lili Chen Lang Chen Hang Xue Adriana CPanayi Wu Zhou Yun sun Faqi Cao Guodong liu Liangcong Hu Chenchen Yan Xudong Xie Chuanchuan Lin Kaiyong Cai Qian Feng Bobin Mi Guohui liu Department of Orthopaedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration Wuhan430022China Key Laboratory of Biorheological science and Technology Ministry of EducationCollege of BioengineeringChongqing UniversityChongqing400044China Division of Plastic surgery Brigham and Women’s HospitalHarvard Medical SchoolBostonMA02152USA Department of Neurosurgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China Medical Center of Trauma and War Injuries Daping HospitalArmy Medical UniversityChongqing400042China Department of stomatology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

A moderate inflammatory response at the early stages of fracture healing is necessary for callus ***-active and continuous inflammation,however,impairs fracture healing and leads to excessive tis.ue *** fracture healing could be promoted through suppression of local over-active immune cells in the fracture *** the present s.udy,we achieved an enriched concentration of PD-L1 from exosomes(Exos)of a genetically engineered Human umbilical Vein Endothelial Cell(HuVECs),and demonstrated that exosomes overexpressing PD-L1 specifically bind to PD-1 on the T cell surface,suppressing the activation of T ***,exosomal PD-L1 induced Mesenchymal stem Cells(MsCs)towards osteogenic differentiation when pre-cultured with T ***,embedding of Exos into an injectable hydrogel allowed Exos delivery to the surrounding microenvironment in a time-released ***,exosomal PD-L1,embedded in a hydrogel,markedly promoted callus formation and fracture healing in a murine model at the early over-active inflammation ***,our results suggested that activation of T cells in the peripheral lymphatic tis.ues was inhibited after local administration of PD-L1-enriched Exos to the fracture sites,while T cells in distant immune organs such as the spleen were not *** summary,this s.udy provides the first example of using PD-L1-enriched Exos for bone fracture repair,and highlights the potential of Hydrogel@Exos systems for bone fracture therapy through immune inhibitory effects.

关键词： PD-L1 Exosome Fracture healing Hydrogel Immunotherapy

基于胎儿游离DNA的产前检测失败因素的研究进展

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中华围产医学杂志 2023年第9期26卷 714-718页

作者：王瑞刘瑗西北妇女儿童医院医学遗传中心西安710061

本文介绍了基于胎儿游离DNA(cell-free fetal DNA,cffDNA)的产前检测失败发生率和原因,以及检测失败后的应对措施。根据检测平台的不同,基于cffDNA的产前检测失败率也存在差异,一般为0.12%~8.09%,其中大规模平行测序的失败率最低。造成... 详细信息

本文介绍了基于胎儿游离DNA(cell-free fetal DNA,cffDNA)的产前检测失败发生率和原因,以及检测失败后的应对措施。根据检测平台的不同,基于cffDNA的产前检测失败率也存在差异,一般为0.12%~8.09%,其中大规模平行测序的失败率最低。造成检测失败的原因主要有三:一是cffDNA浓度低于4%,属于最常见的原因;二是实验室检测过程中DNA提取、文库构建、测序、分析失败;三是检测前血液采集和样本运送到实验室出现的问题。在检测前应充分告知孕妇基于cffDNA的产前检测失败的可能性及相关风险,检测失败后为孕妇综合评估检测失败的原因及重复检测的可行性,制定个体化的产前遗传学检测方案。这对于缓解孕妇面临重复检测的焦虑或决定是否选择介入性产前诊断具有重要的临床意义。

关键词：非侵入性产前检测游离核酸产前诊断

Temporal profiles of the glial roles and neuroimages in APP/Ps1 transgenic AD mice

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Temporal profiles of the glial roles and neuroimages in APP/...

summary of Report on Cardiovas.ular Diseases in China,2012

中国解剖学会2019年年会

作者： liu Lifen liu Yutong Wu Dandan Huang Liang yuan Qionglan Tongji university school of Medicine Department of Radiology University of Nebraska Medical Center

＜正＞Although glial alterations are hallmarks of Alzheimer’s disease （AD） patients,their early roles in amyloid-beta （Aβ） deposits are *** this s.udy,we explored the temporal profiles of glial alteration and neurogenesis and neuroimages in APP/Ps1 transgenic AD *** found that microglia and astrocytes were initially activated and clustered around Aβplaques at the age of 6 months and increased with ***

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Biomedical and Environmental sciences 2014年第7期27卷 552-558页

作者： WANG Wen Hu sheng shou KONG Ling Zhi GAO Run Lin ZHu Man Lu WANG Yong Jun Wu Zhao su CHEN Wei Wei YANG Jin Gang MALi yuan liu Ming Bo For the editorial board National Center for Cardiovas.ular Diseases Beijing 100037 China. National Health and Family PlanningCommission of the People's Republic of China Beijing 100044 China. Beijing Tiantan Hospital 8eijing 100050 China. Beijing Anzhen Hospital Beijing 100029 China.

The prevalence of cardiovas.ular diseases （CVDs） is associated with the socioeconomic prosperity, lifestyle changes, accelerated process of ageing and urbanization. The prevalence of CVDs is continuously increasing in China and will remain an upward trend in the next 10 years. CVDs are the leading cause of death for Chinese in both urban area and rural area. Nowadays, 41.09% of deaths in rural area and 42.52% of deaths in urban area are caused by CVDs in China. The burden of CVDs remains heavy and has become an important public health problem. Effective strategies should be enforced urgently for the prevention of CVDs.under the supervision of the government. In 2012, the Ministry of Health of China and 14 governmental departments jointly is.ued the Work Plan for Chronic Disease Prevention and Control in China （2012-2015）, a guideline for the prevention of chronic diseases, especially CVDs in China.

关键词： area summary of Report on Cardiovas.ular Diseases in China,2012