Temporal profiles of the glial roles and neuroimages in APP/PS1 transgenic AD mice
作者单位:Tongji University School of Medicine Department of RadiologyUniversity of Nebraska Medical Center
会议名称:《中国解剖学会2019年年会》
会议日期:2019年
学科分类:1002[医学-临床医学] 100203[医学-老年医学] 10[医学]
摘 要:正Although glial alterations are hallmarks of Alzheimer’s disease (AD) patients,their early roles in amyloid-beta (Aβ) deposits are *** this study,we explored the temporal profiles of glial alteration and neurogenesis and neuroimages in APP/PS1 transgenic AD *** found that microglia and astrocytes were initially activated and clustered around Aβplaques at the age of 6 months and increased with ***