检索结果-南通市图书馆

Fecal microbiota transplantation in patients with metabolic syndrome and obesity:A randomized controlled trial

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第19期11卷 4612-4624页

作者： Alberto Machado da Ponte Neto Aniele Cristine ott Clemente Paula Waki rosa Igor Braga ribeiro Mateus Pereira Funari Gabriel Cairo Nunes Luana Moreira Luiz Gustavo sparvoli ramon Cortez Carla romano Taddei Márcio C Mancini Eduardo Guimarães Hourneaux de Moura Departament of Gastroenterology Faculdade de MedicinaUniversidade de Sao PauloServiço de Endoscopia Gastrointestinal do Hospital das Clínicas HCFMUSPSão Paulo 05403-010SPBrazil Department of Endocrinology Hospital das ClínicasUniversity of São Paulo School of MedicineSão Paulo 05403-010SPBrazil Department of Clinical and Toxicology Analysis School of Pharmaceutical SciencesUniversity of São PauloSão Paulo 05403-010SPBrazil school of Arts Science and HumanitiesUniversity of São PauloSão Paulo 05403-010SPBrazil

BACKGrOUND Metabolic syndrome is a multifactorial disease,and the gut microbiota may play a role in its ***,especially abdominal obesity,is associated with insulin resistance,often increasing the risk of type two diabetes mellitus,vascular endothelial dysfunction,an abnormal lipid profile,hypertension,and vascular inflammation,all of which promote the development of atherosclerotic cardiovascular *** To evaluate the outcomes of fecal microbiota transplantation(FMT)in patients with metabolic *** This was a randomized,single-blind placebo-controlled trial comparing FMT and a sham procedure in patients with metabolic *** selected 32 female patients,who were divided into eight groups of four patients *** of the patients were submitted to upper gastrointestinal *** each group,two patients were randomly allocated to undergo FMT,and the other two patients received saline *** patients were followed for one year after the procedures,during which time anthropometric,bioimpedance,and biochemical data were *** patients also had periodic consultations with a nutritionist and an *** primary end point was a change in the gut *** There was evidence of a postprocedural change in microbiota composition in the patients who underwent FMT in relation to that observed in those who underwent the sham ***,we found no difference between the two groups in terms of the clinical parameters *** There were no significant differences in biochemical or anthropometric parameters,between the two groups ***,there were significant postprocedural differences in the microbiota composition between the placebo *** date,clinical outcomes related to FMT remain uncertain.

关键词： Fecal microbiota transplantation Metabolic syndrome Obesity Endoscopy Diabetes mellitus Endocrinology

平板探测器CT评估颅内支架:与多层螺旋CT及常规血管造影在一种新动物模型中的比较

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2011年第5期 509-509页

作者： T.struffert s.ott E.Adamek M.schwarz T.Engelhorn s.Kloska 蔡兆诚 Department of Neuroradiology University of Erlangen-Nuremberg

目的颅内支架后进行密切随诊是必要的,因为支架内再狭窄(Isr)或残存狭窄(rs)并不少见。用于微创随访的成像技术是需要的。本研究目的是在一种新的动物模型中比较静脉注射对比剂后平板探测器CT血管成像(FD-CTA)

关键词：血管造影平板探测器CT 动物模型多层螺旋CT 颅内支架

静脉注射平板探测器CT血管成像技术无创性显示颅内血流分流器:技术可行性研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2011年第5期 510-510页

作者： T.struffert M.saake s.ott T.Engelhorn P.Glitz s.Kloska 蔡兆诚 Department of Neuroradiology University of Erlangen-Nuremberg

目的探讨静脉注射平板探测器CT血管成像(FD-CTA)技术显示颅内血流分流器的可行性。血流分流器越来越多地用于颅内动脉瘤的治疗。很明显,大多数动脉瘤的分流器治疗仍需要特批,因此,治疗后密切随诊是非常必

关键词：平板探测器CT 血流分流器多层螺旋CT 血管造影分级

进行性对称性红斑角化病:Darier-Gottron

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（皮肤病学分册） 2005年第3期1卷 10-11页

作者： ott H. Lehmann s. Poblete-Gutié rrez P. Frank J. 牛新武 Ab t. fur M olekulare Dermatologie Klin. fur Dermatol. und Allergologie Universitatsklinik um der RWTH Aachen Pauwelsstra.e 30 52074 Aachen GermanyDr.

A 5 1/2-year-old boy revealed symmetric erythematous plaques on b oth arms and legs as well as in the face. Additionally, contractions of several digital joints were noted. We diagnosed a progressive symmetric erythrokeratoderma and i nitiated a topical therapy with tretinoin. Here we discuss the etiology, differe ntial diagnoses, and therapeutic options of this rare disorder of keratinization .

关键词： Darier-Gottron 对称性红斑角化性疾病鉴别诊断病因学

维普期刊数据库

采用时间-密度曲线测量弹性蛋白酶诱导的动脉瘤模型的量化参数:血流导向支架与传统动脉瘤支架比较的初步结果

在线全文

学校读者我要写书评

暂无评论

国际医学放射学杂志 2013年第2期 201-202页

作者： T. struffert s. ott M. Kowarschik F. Bender E. Adamek T. Engelhorn 李宁 Department of Neuroradiology University of Erlangen-Nuremberg Schwabachanlage 6 91054 Erlangen Germany

研究背景采用量化参数评估血流导向支架(FD)的有效性是可行的。对经支架[neuroform(NF)]和引流器(FD)[管道栓塞装置(pipelineembolisationdevice,PED)]治疗后的弹性蛋白酶诱导的兔动脉瘤模型进行时间-密度曲线(TDC)测量及量化参数计算... 详细信息

研究背景采用量化参数评估血流导向支架(FD)的有效性是可行的。对经支架[neuroform(NF)]和引流器(FD)[管道栓塞装置(pipelineembolisationdevice,PED)]治疗后的弹性蛋白酶诱导的兔动脉瘤模型进行时间-密度曲线(TDC)测量及量化参数计算。方法 16例弹性蛋白酶诱导的兔动脉瘤采用FD(n=9)或NF(n=5)治疗。分别于治疗前及治疗后行血管造影并生成TDC。计算达峰时间(TTP)、半峰全宽(FWHM)及代表流入(IF)流出(OF)的曲线平均斜率。结果治疗前的平均值分别为TTP=0.8s,FWHM=1.2s,IF=153.5及OF=-54.9。经PED治疗后,TTP及FWHM均延长,分别为1.8s和47.8s。IF及OF随即延迟,分别为31.2s和-11.5s。经NF治疗后各值略有改变(TTP=1.1s,FWHM=1.8s,IF=152.9,OF=-33.2)。结论采用兔动脉瘤模型生成TDC是可行的。描述PED及NF血流动力学效应的参数可以计算出,并且使用器械不同参数不同。这些参数或许可以作为动脉瘤闭塞的预测指标。要点①可脱性弹簧圈现在已取代外科手术广泛应用于治疗颅内动脉瘤。②动脉瘤的时间-密度曲线能够提示降低动脉瘤内血流的效果。③目前时间-密度曲线可以通过软件模型进行测量。④经血流导向支架或传统支架治疗后的时间-密度曲线是不同的。⑤可以计算时间-密度曲线的参数,并且可以作为预测参数。

关键词：时间-密度曲线颅内动脉瘤血流导向支架血管造影血管内治疗

recent advances and perspectives in next generation sequencing application to the genetic research of type 2 diabetes

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2019年第7期10卷 376-395页

作者： Yulia A Nasykhova Yury A Barbitoff Elena A serebryakova Dmitry s Katserov Andrey s Glotov Laboratory of Biobanking and Genomic Medicine of Institute of Translation Biomedicine St.Petersburg State UniversitySt.Petersburg 199034Russia Department of Genomic Medicine D.O.Ott Research Institute of ObstetricsGynaecology and ReproductologySt.Petersburg 199034Russia Bioinformatics Institute St.Petersburg 194021Russia Department of Genetics and Biotechnology St.Petersburg State UniversitySt.Petersburg 199034Russia Department of Genetics City Hospital No.40St.Petersburg 197706Russia Institute of Living systems Immanuel Kant Baltic Federal UniversityKaliningrad 236016Russia

Type 2 diabetes(T2D)mellitus is a common complex disease that currently affects more than 400 million people worldwide and has become a global health ***-throughput sequencing technologies such as whole-genome and whole-exome sequencing approaches have provided numerous new insights into the molecular bases of *** advances in the application of sequencing technologies to T2D research include,but are not limited to:(1)Fine mapping of causal rare and common genetic variants;(2)Identification of confident genelevel associations;(3)Identification of novel candidate genes by specific scoring approaches;(4)Interrogation of disease-relevant genes and pathways by transcriptional profiling and epigenome mapping techniques;and(5)Investigation of microbial community alterations in patients with *** this work we review these advances in application of next-generation sequencing methods for elucidation of T2D pathogenesis,as well as progress and challenges in implementation of this new knowledge about T2D genetics in diagnosis,prevention,and treatment of the disease.

关键词： Type 2 diabetes Next-generation sequencing Epigenetics Genome-wide association study Microbiome

Draft of spanish standard for the Use of recycled Aggregate in the Production of structural Concrete

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Draft of Spanish Standard for the Use of Recycled Aggregate ...

青少年多囊卵巢综合征:基于Mr成像的诊断标准

The 6th International symposium on Cement & Concrete and Canmet/Aci International symposium on Concrete Technology for sustainable Development

作者： Pilar Alaejos Marta sánchez de Juan Marilda Barra Manuel Burón Enrique Dapena Miren Etxebarría Gilbert Francisco Belén González Fonteboa Fernando Martínez abella Isabel Martínez Lage José Luis Parray Alfaro Juan Antonio Polanco Mariano sanabria Enric Vázquez Task Force of standing Committee of Concrete

In November 2002, the spanish standing committee of Concrete created a task force commissioned to draft a document to complement current regulations on structural concrete and to set out specific reco

关键词： recycled concrete aggregate, standardization, structural concrete.

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

国际医学放射学杂志 2018年第1期 106-106页

作者： M.Fondin A.rachas V.Huynh s.Franchi-abella J.P.Teglas L.Duranteau 徐凯 Department of Pediatric Imaging Centre for Research in Epidemiology and Population Health

摘要目的评价基于Mr影像诊断青少年多囊卵巢综合征(PCOs)形态学特征的有效性和可重复性。材料与方法本病例-对照研究共纳入110例自2006—2015年进行过盆

关键词：多囊卵巢综合征可重复性 Mr 诊断标准

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

医院内心脏骤停的心肺复苏质量

美国医学会杂志（中文版） 2006年第1期25卷 17-21页

作者： Bonjamin s. abella Jason P. Alvarado Helge Myklebust, Beng Dana P. Edelson Anne Barry, rN, MBA Nicholas O＇ Hearn, rN, MsN Terry L Vanden Hoek Lance B. Becker 方跃华（译）沈卫峰（校） sections of Emergency Medicine sections of Emergency Medicine and Critical Care University of Chicago Hospitals Chicago lll and Laerdal Medical Corporation Stavangerl Norway 不详

背景：正确进行心肺复苏（cardiopulmory resuscitation，CPr）能提高存活率已被公认，但尚缺乏心脏骤停时实际CPr质量的客观资料。最近的研究已对按照现行国际指南统一实施CPr这一观念提出了挑战。目的：测定院内CPr质量的多个参数，... 详细信息

背景：正确进行心肺复苏（cardiopulmory resuscitation，CPr）能提高存活率已被公认，但尚缺乏心脏骤停时实际CPr质量的客观资料。最近的研究已对按照现行国际指南统一实施CPr这一观念提出了挑战。目的：测定院内CPr质量的多个参数，确定临床对美国心脏病协会和国际指南的依从性。设计和对象：对2002年12月11日至2004年4月5日芝加哥大学医院内发生的67例心脏骤停患者进行前瞻性观察研究。使用一种新的附加感应功能的监护／除颤仪，记录的CPr质量参数包括胸外按压频率、按压深度、通气频率和无胸外按压的停搏时间段（无血流分数）。主要观察指标：对美国心脏病协会和国际CPr指南的坚持程度。结果：按照30秒时段对每例复苏最初5分钟进行分析发现，在28．1％的时段胸外按压频率低于90次／min。37．4％按压深度过浅（〈38mm）。通气频率较高，60．9％的时段频率超过20次／min。此外，平均（sD）无血流分数为0．24（0．18）。心脏骤停时每分钟有10秒钟的停顿将产生0．17的无血流分数。总共27例（40．3％）成功恢复自主循环，并有7例（10．4％）出院。结论：在本医院内心脏骤停研究，即使CPr由曾受良好训练的医务人员实施，CPr多项参数的质量亦不一致，而且常常与指南的建议不符。高质量CPr的重要性提示，在实施复苏期间需要救护人员的反馈和监测CPr质量。

关键词：质量参数心脏骤停心肺复苏医院内 resuscitation 美国心脏病协会国际指南按压频率胸外按压 CPr