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systematic security Guideline Framework through Intelligently Automated Vulnerability Analysis

Computers, Materials & Continua 2024年第3期78卷 3867-3889页

作者： Dahyeon Kim Namgi Kim Junho ahn Computer Information Technology Korea National University of TransportationChungju27469Korea Department of AI Computer science and Engineering Kyonggi UniversitySuwon16227Korea

This research aims to propose a practical framework designed for the automatic analysis of a product’s comprehensive functionality and security vulnerabilities,generating applicable guidelines based on real-world *** exis.ing analysis of software security vulnerabilities often focuses on specific features or *** partial and arbitrary analysis of the security vulnerabilities makes it challenging to comprehend the overall security vulnerabilities of the *** key novelty lies.in overcoming the constraints of partial *** proposed framework utilizes data from various sources to create a comprehensive functionality profile,facilitating the derivation of real-world security *** guidelines are dynamically generated by associating functional security vulnerabilities with the latest Common Vulnerabilities and Exposure(CVE)and Common Vulnerability scoring system(CVss)scores,resulting in automated guidelines tailored to each *** guidelines are not only practical but also applicable in real-world software,allowing for prioritized security *** proposed framework is applied to virtual private network(VPN)software,wherein a validated Level 2 data flow diagram is generated using the spoofing,Tampering,Repudiation,Information Disclosure,Denial of service,and Elevation of privilege(sTRIDE)technique with references to various papers and examples from related *** analysis resulted in the identification of a total of 121 *** successful implementation and validation demonstrate the framework’s efficacy in generating customized guidelines for entire systems,subsystems,and selected modules.

关键词： Framework automation vulnerability analysis security guidelines

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Composite Recommendation of Artworks.in E-Commerce Based on User Keyword-Driven Correlation Graph search

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Tsinghua science and Technology 2024年第1期29卷 174-184页

作者： Jingyun Zhang Wenjie Zhu Byoung Jin ahn Yongsheng Zhou school of Design Dongseo UniversityBusan 47011Republic of Korea Institute of Art and Design Jiangsu University of TechnologyChangzhou 213001China Jinling Wenyun Art Design Co. Ltd.Zhenjiang 212000China Institute of Art and Design Krirk UniversityBangkok 10220Thailand shandong Provincial University Laboratory for Protected Horticulture Weifang University of Science and TechnologyShouguang 262700China

With the ever-increasing diversification of people’s.interests and preferences,artwork has become one of the most popular commodities or investment goods.in E-commerce,and it increasingly attracts the attention of the ***,many real-world or virtual artworks can be found in E-commerce,and finding a means to recommend them to appropriate users has become a significant task to alleviate the heavy burden on artwork selection decisions by *** research mainly studies the problem of single-artwork recommendation while neglecting the more practical but more complex composite recommendation of artworks.in E-commerce,which considerably influences the quality of experience of potential users,especially when they need to select a set of artworks.instead of a single *** by this limitation,we put forward a novel composite recommendation approach to artworks by a user keyword-driven correlation graph search named ART_(com-rec).Through ART_(com-rec),the recommender system can output a set of artworks(e.g.,an artwork composite solution)in E-commerce by considering the keywords typed by a user to indicate his or her personalized ***,we validate the feasibility of the ART_(com-rec) approach by a set of simulated experiments on a real-world PW dataset.

关键词： composite recommendation artwork user keywords E-commerce correlation graph search

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Uniportal video-assisted thoracoscopic fissureless right upper lobe anterior segmentectomy for inflammatory myofibroblastic tumor:A case report

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World Journal of Clinical Cases 2024年第2期12卷 425-430页

作者： seha ahn Youngkyu Moon Department of Thoracic and Cardiovascular surgery Eunpyeong St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 03312South Korea

BACKGROUND Inflammatory myofibroblastic tumors(IMTs)are exceptionally rare neoplasms with intermediate malignant *** is the accepted treatment option,aiming for complete resection with clear *** sUMMARY A 39-year-old woman presented with a growing solitary pulmonary nodule measuring 2.0 cm in the right upper lobe(RUL)of the *** patient underwent a RUL anterior segmentectomy using uniportal video-assisted thoracoscopy.A preliminary tissue diagnosis.indicated malignancy;however,it was later revised to an *** to the absence of a minor fissure between the right upper and middle lobes,an alternative resection approach was ***,we utilized indocyanine green injection to aid in delineating the intersegmental *** an uneventful recovery,the patient was discharged on the third postoperative ***,annual chest tomography scans were scheduled to monitor for potential local *** This case underscores the challenges.in diagnosing and managing IMTs,showing the importance of accurate pathologic assessments and tailored surgical strategies.

关键词： Uniportal video-assisted thoracoscopic surgery Fissureless Anterior segmentectomy Inflammatory fibroblastic tumor Case report

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Fibrinogen’s potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer’s disease

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Neural Regeneration Research 2025年第1期20卷 203-204页

作者： Vishal singh Arnab Choudhury Hyung Jin ahn Department of Pharmacology Physiology and NeurosciencesRutgers-New Jersey Medical SchoolNewarkNJUSA Brain Health Institute Rutgers UniversityPiscatawayNJUSA

Alzheimer’s disease(AD)stands out as the primary manifestation of age-related dementia,portraying a chronic neurodegenerative disorder dis.inguished by the accumulation of fibrillar amyloid-β(Aβ)plaques and neurofibrillary tangles of hyperphosphorylated ***,from a clinical standpoint,AD presents itself as a complex condition with a spectrum of dysfunctions rather than a singular pathological *** often-overlooked aspect of the disease is the presence of extensive cerebrovascular abnormalities,given that the majority of AD patients experience altered cerebral blood flow,damaged vasculature,increased microinfarcts and *** models of AD further support this observation,showing cerebrovascular dysfunction such as impaired cerebral blood flow and altered cerebrovascular reactivity(Tataryn et al.,2021;Gareau et al.,2023).

关键词： cerebrovascular dysfunction Alzheimer

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surface doping effect on the optoelectronic performance of 2D organic crystals based on cyano-substituted perylene diimides

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Chinese Chemical Letters 2024年第9期35卷 193-197页

作者： Jaeyong ahn Zhenping Li Zhiwei Wang Ke Gao Huagui Zhuo Wanuk Choi Gang Chang Xiaobo shang Joon Hak Oh school of Chemical and Biological Engineering Institute of Chemical ProcessesSeoul National UniversitySeoul 08826South Korea state Key Laboratory for Mechanical Behavior of Materials Shaanxi International Research Center for Soft MatterSchool of Materials Science and EngineeringXi’an Jiaotong UniversityXi’an 710049China Center for Ordered Nanoporous Materials synthesis School of Environmental Science and EngineeringPohang University of Science and TechnologyGyeongbuk 37673South Korea Instrumental Analysis Center of Xi’an Jiaotong University Xi’an 710049China

Compared to organic thin films,organic single crystals offer significant potential in organic phototransistors(OPTs)due to their enhanced charge transport,large surface area,and defect-free ***,the development of n-type semiconductors has lagged behind p-type *** enhance semiconductor device performance,a doping process can be employed,which typically involves the introduction of charged impurities.into the crystalline semiconducting *** aim is to reduce the Ohmic losses.increase carrier density,improve transport capabilities,and facilitate effective carrier injection,ultimately enhancing the electrical properties of the *** doping processes,however,often pose a risk of damaging the structure of single *** this study,we have synthesized novel cyanosubstituted chiral perylene diimides,which self-assemble into two-dimensional single crystals that can be used for n-type semiconductor *** have employed a surface doping strategy using diethylamine vapor without disrupting the crystal *** fabricated devices exhibit significantly higher charge transport properties after doping,achieving a maximum electron mobility of 0.14 cm^(2)V^(-1)s^(-1),representing an improvement of over ***,the optoelectronic performance of the doped devices has significantly improved,with the external quantum efficiency increased by over 9 times and the significantly improved response *** results suggest that our surface doping technology is a promising way for enhancing the performance of 2D organic single-crystal OPTs.

关键词： Doping effect Phototransistors Perylene diimides Organic crystals Cyano substitution

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Unraveling the Harmonious Coexistence of Ruthenium states on a self-standing Electrode for Enhanced Hydrogen Evolution Reaction

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ENERGY & ENVIRONMENTAL MATERIALs 2024年第6期7卷 303-311页

作者： Ma, Joonhee Cho, Jin Hyuk Lee, Chaehyeon Kang, Moon sung Choi, sungkyun Jang, Ho Won ahn, sang Hyun Back, seoin Kim, soo Young Korea Univ Dept Mat Sci & Engn Seoul 02841 South Korea sogang Univ Inst Emergent Mat Dept Chem & Biomol Engn Seoul 04107 South Korea Pusan Natl Univ Coll Nanosci & Nanotechnol Dept Cogno Mechatron Engn Busan 46241 South Korea seoul Natl Univ Res Inst Adv Mat Dept Mat Sci & Engn Seoul 08826 South Korea Chung Ang Univ Sch Chem Engn & Mat Sci Seoul 06974 South Korea

The development of cost-effective, highly efficient, and durable electrocatalysts has been a paramount pursuit for advancing the hydrogen evolution reaction (HER). Herein, a simplified synthesis protocol was designed to achieve a self-standing electrode, composed of activated carbon paper embedded with Ru single-atom catalysts and Ru nanoclusters (ACP/RusAC+C) via acid activation, immersion, and high-temperature pyrolysis. Ab initio molecular dynamics (AIMD) calculations are employed to gain a more profound understanding of the impact of acid activation on carbon paper. Furthermore, the coexistence states of the Ru atoms are confirmed via aberration-corrected scanning transmission electron microscopy (AC-sTEM), X-ray photoelectron spectroscopy (XPs), and X-ray absorption spectroscopy (XAs). Experimental measurements and theoretical calculations reveal that introducing a Ru single-atom site adjacent to the Ru nanoclusters.induces a synergistic effect, tuning the electronic structure and thereby significantly enhancing their catalytic performance. Notably, the ACP/RusAC+C exhibits a remarkable turnover frequency (TOF) of 18 s-1 and an exceptional mass activity (MA) of 2.2 A mg-1, surpas.ing the performance of conventional Pt electrodes. The self-standing electrode, featuring harmoniously coexis.ing Ru states, stands out as a prospective choice for advancing HER catalysts, enhancing energy efficiency, productivity, and selectivity. A self-standing electrode with the coexistence of Ru single atoms and Ru nanoclusters is designed for the hydrogen evolution reaction (HER). Additional acid activation process.induces defects, anchoring more Ru ions on the substrate. Detailed experimental and computational investigations suggest that the electronic coupling effect between different Ru states significantly enhanced the overall HER performance. image

关键词： electrocatalysis electronic coupling effect hydrogen evolution reaction self-standing electrode CARBON ELECTROREDUCTION CATALYsTs PAPER

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Prevalence of nonalcoholic fatty liver disease in pediatrics and adolescents:a systematic review and meta-analysis

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World Journal of Pediatrics 2024年第6期20卷 569-580页

作者： Eun Joo Lee Miyoung Choi sang Bong ahn Jeong-Ju Yoo seong Hee Kang Yuri Cho Do seon song Hong Koh Dae Won Jeon Hye Won Lee Department of Pediatrics Yonsei University College of MedicineSeoulKorea Clinical Evidence Research National Evidence-Based Healthcare Collaborating Agency(NECA)SeoulKorea Department of Internal Medicine Nowon Eulji Medical CenterEulji University College of MedicineSeoulKorea Department of Internal Medicine Soonchunhyang University Bucheon HospitalBucheonKorea Department of Internal Medicine Sangkye Paek HospitalInje University College of MedicineSeoulKorea Center for Liver and Pancreatobiliary Cancer National Cancer CenterGoyangKorea Department of Internal Medicine College of MedicineSt.Vincent's HospitalThe Catholic University of KoreaSuwonKorea Department of Internal Medicine Hanyang University College of MedicineSeoulKorea Department of Internal Medicine Yonsei University College of MedicineSeoulKorea

Background As childhood obesity escalates worldwide,the prevalence of nonalcoholic fatty liver disease(NAFLD)in pediatric and adolescent populations is also ***,systematic studies and meta-analyses evaluating the prevalence of pediatric NAFLD remain *** The MEDLINE,Korean Medical Database(KMBAsE),Embase,Global Health,and Cochrane Library databases were searched from January 1997 to April *** terms.included NAFLD or steatosis;nonalcoholic or steatohepatitis;child(ren),adolescent,or teenager;and prevalence,incidence,or epidemiology.A random-effects meta-analysis model was used to estimate the prevalence of pediatric *** A total of 2116 publications were found,of which 62 were included in the *** them,27 reported the prevalence in the general population and 39 in the obese *** worldwide pooled prevalence of pediatric NAFLD was 13%[95%confidence interval(CI)9-18%]in the general population and 47%(95%CI 41%–53%)in the obese *** 16 studies.in the general population and 18 in the obese population,NAFLD prevalence varied by *** the general population,the prevalence of NAFLD was 15%(95%CI 8%–23%)in males and 10%(95%CI 6%–15%)in *** the obese population,it was 54%(95%CI 46%–61%)in males and 39%(95%CI 30%–49%)in *** The global prevalence of pediatric NAFLD is rising in both the general and obese *** the increasing rates of childhood obesity,epidemiological studies on the prevalence and incidence of NAFLD are needed.

关键词： Meta-analysis Nonalcoholic fatty liver disease Pediatric Prevalence

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Acupuncture ameliorates atopic dermatitis by modulating gut barrier function in a gut microbiota-dependent manner in mice

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Journal of Integrative Medicine 2024年第5期22卷 600-613页

作者： Mijung Yeom sora ahn Dae-Hyun Hahm sun-Young Jang se Hoon Jang su-Yang Park Jae-Hwan Jang Jihan Park Ju-Young Oh In-seon Lee Kyuseok Kim soon-Kyeong Kwon Hi-Joon Park Acupuncture and Meridian science Research Center College of Korean MedicineKyung Hee University Department of Physiology School of MedicineKyung Hee University BioNanocomposite Research Center Kyung Hee University Department of science in Korean Medicine College of Korean MedicineGraduate SchoolKyung Hee University College of Korean Medicine Kyung Hee University Department of Ophthalmology Otorhinolaryngology and Dermatology of Korean MedicineCollege of Korean MedicineKyung Hee University Division of Applied Life science (BK21) Gyeongsang National University Department of Anatomy & Information sciences College of Korean MedicineKyung Hee University

Objective: Atopic dermatitis(AD) is a chronic inflammatory s.in disease that may be linked to changes.in the gut microbiome. Acupuncture has been proven to be effective in reducing AD symptoms without serious adverse events, but its underlying mechanism is not completely understood. The purpose of this study was to investigate whether the potential effect of acupuncture on AD is gut ***: AD-like s.in lesions were induced by applying MC903 topically to the cheek of the *** was done at the Gok-Ji(LI11) acupoints. AD-like symptoms were assessed by lesion scores,scratching behavior, and histopathological changes; intes.inal barrier function was measured by fecal output, serum lipopolysaccharide levels, histopathological changes, and mRNA expression of markers.involved in intes.inal permeability and inflammation. Gut microbiota was profiled using 16s rRNA gene sequencing from fecal ***: Acupuncture effectively improved chronic itch as well as the AD-like s.in lesions with epidermal thickening, and also significantly altered gut microbiota structure as revealed by β-diversity indices and analysis of similarities. These beneficial effects were eliminated by antibiotic depletion of gut microbiota,but were reproduced in gut microbiota-depleted mice that received a fecal microbiota transplant from acupuncture-treated mice. Interes.ingly, AD mice had intes.inal barrier dysfunction as.indicated by increased intes.inal permeability, atrophy of the mucosal structure(reduced villus height and crypt depth), decreased expression of tight junctions and mucus synthesis genes, and increased expression of inflammatory mediators.in the ileum. Acupuncture attenuated these abnormalities, which was gut ***: Acupuncture ameliorates AD-like phenotypes.in a gut microbiota-dependent manner and some of these positive benefits are explained by modulation of the intes.inal barrier, providing new perspective for non-phar

关键词： Acupuncture Atopic dermatitis Gut microbiota Intes.inal barrier function

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电沉积Mo和Mo-Co合金纳米线用于互联电阻的电阻率改性

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Engineering 2024年第1期32卷 127-137页

作者： Jun Hwan Moon Taesoon Kim Youngmin Lee seunghyun Kim Yanghee Kim Jae-Pyoung ahn Jungwoo Choi Hyuck Mo Lee Young Keun Kim Department of Materials science and Engineering Korea UniversitySeoul 02841Republic of Korea Department of Materials science and Engineering Korea Advanced Institute of Science and EngineeringDaejeon 34141Republic of Korea Advanced Analysis Center Korea Institute of Science and TechnologySeoul 02792Republic of Korea Research Resources Division Korea Institute of Science and TechnologySeoul 02792Republic of Korea

Achieving historically anticipated improvement in the performance of integrated circuits is challenging,due to the increasing cost and complexity of the required technologies with each new *** overcome this limitation,the exploration and development of novel interconnect materials and processes are highly desirable in the microelectronics ***(Mo)is attracting attention as an advanced interconnect material due to its small resistivity size effect and high cohesive energy;however,effective proces.ing methods for such materials have not been widely ***,we investigate the electrochemical behavior of ions.in the confined nanopores that affect the electrical properties and microstructures of nanoscale Mo and Mo-Co alloys prepared via template-assisted *** in an electrolyte allow the deposition of extremely pure metal materials,due to their interac-tion with metal ions and *** this study,boric acid and tetrabutylammonium bisulfate(TBA)were added to an acetate bath to inhibit the hydrogen evolution *** accelerated the reduction of Mo at the surface by inducing surface conduction on the *** Mo nanowires with a 130 nm diameter synthesized through high-aspect-ratio nanopore engineering exhibited a resistivity of(63.0±17.9)μΩ*** also evaluated the resistivities of Mo-Co alloy nanowires at various compo-sitions toward replacing irreducible conventional barrier/liner *** intermetallic compound formed at a Mo composition of 28.6 at%,the resistivity of the Mo-Co nanowire was(58.0±10.6)μΩcm,indicat-ing its superior electrical and adhesive properties.in comparison with those of conventional barriers such as TaN and ***,density functional theory and non-equilibrium Green's function calcula-tions confirmed that the vertical resistance of the via structure constructed from Mo-based materials was 21%lower than that of a conventional Cu/Ta/TaN structure.

关键词： Molybdenum Molybdenum-cobalt Interconnect Microstructure Electrodeposition Density functional theory

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Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin:Creation of an unnatural analogue with improved anticancer properties

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Acta Pharmaceutica sinica B 2024年第1期14卷 421-432页

作者： Dexiu Yan Jemma Arakelyan Teng Wan Ritvik Raina Tsz Ki Chan Dohyun ahn Vladimir Kushnarev Tsz Kiu Cheung Ho Ching Chan Inseo Choi Pui Yi Ho Feijun Hu Yujeong Kim Hill Lam Lau Ying Lo Law Chi seng Leung Chun Yin Tong Kai Kap Wong Wing Lam Yim Nikolay s.Karnaukhov Richard Y.C.Kong Maria V.Babak Yudai Matsuda Department of Chemistry City University of Hong KongHong Kong SARChina iGEM Team“VarieCure” City University of Hong KongHong Kong SARChina Department of Biomedical Engineering City University of Hong KongHong Kong SARChina Moscow Clinical Research Center Named After A.s.Loginov Moscow 111123Russian Federation

A biosynthetic gene cluster for the bioactive fungal sesterterpenoids variecolin(1)and variecolactone(2)was identified in Aspergillus aculeatus ATCC *** production of 1 and 2 was achieved in Aspergillus oryzae by expres.ing the sesterterpene synthase VrcA and the cytochrome P450 ***,the replacement of VrcB with homologous P450s from other fungal terpenoid pathways yielded three new variecolin analogues(5-7).Analysis of the compounds’anticancer activity in vitro and in vivo revealed that although 5 and 1 had comparable activities,5 was associated with significantly reduced toxic side effects.in cancer-bearing mice,indicating its potentially broader therapeutic *** study describes the first tests of variecolin and its analogues.in animals and demonstrates the utility of synthetic biology for creating molecules with improved biological activities.

关键词： Animal studies Anticancer properties Biosynthesis Natural products sesterterpenoids synthetic biology Terpene synthases Variecolin

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