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Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates

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genes & Diseases 2024年第1期11卷 34-37页

作者： Budhadev Baral Dharmendra Kashyap Nidhi Varshney Tarun Prakash Verma Ajay Kumar Jain Debi Chatterji vinod Kumar Amit Mishra Awanish Kumar Hem Chandra Jha Infection Bioengineering group Department of Biosciences and Biomedical EngineeringIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Choithram Hospital and Research Center IndoreMadhya Pradesh452014India Department of Metallurgy Engineering and Materials science Indian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Department of Bioscience&Bioengineering Indian Institute of Technology JodhpurNH 65 Nagaur RoadJodhpur DistrictKarwarRajasthan 342037India Department of Biotechnology National Institute of Technology RaipurGE RoadRaipurChhattisgarh 492010India

Persistent gastritis induced by Helicobacter pylori(***)is the strongest known risk factor for gastric cancer(gC).*** is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that *** infection can induce oncogenic properties in Ags cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.

关键词： H.pylori pylori Helicobacter

Database search Behaviors: Ins.g.t from a survey of Information Retrieval Practices

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Intelligent Information Management 2024年第5期16卷 195-218页

作者： Babita Trivedi Brijender Dahiya Anjali Maan Rajesh giri vinod Prasad Department of Physics Swami Shraddhanand College University of Delhi Delhi India Department of Physics Pt.N.R.S.G.C. Rohtak Maharshi Dayanand University Rohtak India Department of Physics Rajdhani College University of Delhi Delhi India

This study examines the database search behaviors of individuals, focusing on gender differences and the impact of planning habits on information retrieval. Data were collected from a survey of 198 respondents, categorized by their discipline, schooling background, internet us.g., and information retrieval preferences. Key findings indicate that females are more likely to plan their searches in advance and prefer structured methods of information retrieval, such as using library portals and leading university websites. Males, however, tend to use web search engines and self-archiving methods more frequently. This analysis provides valuable ins.g.ts for educational institutions and libraries to optimize their resources and services based on user behavior patterns.

关键词： Information Retrieval Database search User Behavior Patterns

均相和非均相催化微藻脂质提取和酯交换制备生物燃料的研究进展

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Chinese Journal of Catalysis 2024年第4期59卷 97-117页

作者： Vinoth Kumar Ponnumsamy Hussein E.Al-Hazmi sutha shobana Jeyaprakash Dharmaraja Dipak Ashok Jadhav Rajesh Banu J grzegorz Piechota Bartłomiej Igliński vinod Kumar Amit Bhatnagar Kyu-Jung Chae gopalakrishnan Kumar 高雄医科大学药物与应用化学系环境医学研究中心中国台湾高雄高雄医科大学医学研究部中国台湾高雄格但斯克理工大学土木与环境工程学院波兰纳鲁特维察格但斯克范朗大学工程与技术学院建筑绿色技术与可持续发展研究组越南胡志明市工程技术学院科学与人文系化学部印度泰米尔纳德邦韩国海洋大学海洋科学与工程学院环境工程系韩国釜山泰米尔纳德邦中央大学生命科学系印度泰米尔纳德邦 gPCHEM沼气研究与分析实验室波兰尼古拉斯哥白尼大学化学系波兰克兰菲尔德大学水与能源学院英国拉彭兰塔工业大学工程科学学院分离科学系芬兰韩国海洋大学海洋可再生能源工程专业韩国釜山延世大学土木与环境工程学院韩国首尔斯塔万格大学科学技术学院化学、生物科学与环境工程研究所挪威斯塔万格

随着化石燃料燃烧导致的二氧化碳排放不断加剧气候变化,且化石燃料储量日益减少,寻求可再生能源已成为一项紧迫的任务.其中,藻类衍生可持续燃料因具有成本优势和可运输性,在解决全球能源危机方面展现出广阔前景,备受关注.利用化学转化... 详细信息

随着化石燃料燃烧导致的二氧化碳排放不断加剧气候变化,且化石燃料储量日益减少,寻求可再生能源已成为一项紧迫的任务.其中,藻类衍生可持续燃料因具有成本优势和可运输性,在解决全球能源危机方面展现出广阔前景,备受关注.利用化学转化技术从微藻中提取脂质,并通过酯交换反应可以将其转化为脂肪酸甲酯,是生产绿色生物燃料的有效途径.这一过程涉及游离脂肪酸、磷脂和甘油三酯的提取,并且生产过程能耗低,成为满足日益增长的能源需求的一种理想解决方案.本文综述了微藻脂质提取和酯交换制备生物燃料的相关研究进展.首先,介绍了微藻脂质的提取方法,包括溶剂提取法、索氏提取法、布利格和戴耶法、超临界二氧化碳提取以及离子液体溶剂法等,并分析了各方法的优缺点.随后,重点阐述了酯交换技术在微藻脂质转化中的应用,包括酸碱催化、酶催化以及原位酯交换反应等,并探讨了这些技术的反应机理、催化剂选择、反应器设计以及生物油生产工艺等方面的研究进展.通过综述上述研究进展,为微藻脂质的生产和应用提供了理论指导.研究表明,通过优化催化剂种类、反应条件以及提取方法,可以有效提高微藻脂质的转化效率和生物油品质.同时,本文也指出了当前微藻脂质生产中面临的挑战,如微藻栽培和生长条件优化、高效转化技术的开发等.随着可持续能源日益受到重视,微藻脂质作为一种可再生能源具有巨大的发展潜力.未来研究应进一步关注微藻的规模化栽培、生长条件优化以及高效转化技术的研发,以提高微藻脂质的产量和品质.同时,应进一步推动和实现微藻生物燃料的实际应用,从而为应对气候变化和能源危机提供有效的解决方案.

关键词：微藻脂质提取酯交换催化酶催化原位技术

Variability in pod and seed traits of Pongamia pinnata Pierre ecotypes in North Karnataka, India

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Journal of Forestry Research 2016年第3期27卷 557-567页

作者： vinod Kumar Patil g.R.Naik Department of Biotechnology Gulbarga University

An evaluation of 30 naturally available candidate-plus trees（CPTs） of Pongamia pinnata was carried out to elucidate the genetic variability and relationship of pod and seed traits and progeny growth traits to select the best planting material with higher productivity. s.g.ificant variations were observed in pod and seed characteristics,oil content, and during the progeny trial studies. The highest values were found in 100-pod weight（410.4 gm）and 100-seed weight（195.92 gm） and the phenotypic and genotypic variance was found maximum in 100 pod weight（4364.71 and 4289.93） and 100 seed weight（813.8 and768.93）, respectively. Estimates of the phenotypic coefficient of variance were higher than the genotypic coefficient of variance for all the pod and seed traits and progeny growth traits, which depict the predominant role of the environment. Approximately 99 % of broad-sense heritability was revealed in oil content, followed by 100-pod weight（98.28 %）, and canopy growth（96.93 %）. Pod thickness shows the highest genetic advance of 56.61 %,followed by pod width（53.43 %） and canopy growth（49.3 %）. Pod and seed traits have proven a positive correlation between each other and with progeny growth traits,except a few negative values. Hierarchical clustering by Ward＇s minimum variance cluster analysis showed phylogeographical patterns of genetic diversity. K-means clustering revealed that trees from different geographical regions were grouped together in a cluster where as trees from the same geographical area are placed in a different cluster. seven Pongamia ecotypes.g.P-8, 9, 13, 14, 18,28, and 29） are found superior in traits, namely 100-pod weight, 100-seed weight, oil content, germination rate,plant height, canopy growth, and collar diameter. The traits100-pod weight and 100-seed weight are highly correlated with the progeny growth traits and even have higher heritability and genetic advantages.

关键词： Biodiesel Morphological diversity Pod andseed traits Pongamia pinnata Progeny trial

H2A.Z at the Core of Transcriptional Regulation in Plants

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Molecular Plant 2018年第9期11卷 1112-1114页

作者： s. vinod Kumar Cell and Developmental Biology Department John Innes Centre Norwich NR4 7UH UK

H2A.Z, an evolutionarily conserved variant form of canonical H2A, has been widely recognized to have decisive roles in multi- ple cellular processes through its influence on chromatin structure and dynamics in eukaryotes. Many of its effects on regulating chromatin function have been attributed to its role in modulating nucleosome dynamics and DNA methylation. In plants, H2A.Z plays critical roles in multiple processes, such as.g.owth and development, phase transitions, and response to the environment. Despite the progress made in understanding its role in these processes, several aspects of H2A.Z biology.

关键词： ARABIDOPsIs ACTIVATION EXPREssION

sWR1 Chromatin-Remodeling Complex subunits and H2A.Z Have Non-overlapping Functions in Immunity and gene Regulation in Arabidopsis

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Molecular Plant 2016年第7期9卷 1051-1065页

作者： souha Berriri sreeramaiah N gangappa and s vinod Kumar Cell and Developmental Biology Department John Innes Centre Norwich NR4 7UH UK

Incorporation of the histone variant H2A.Z into nucleosomes by the sWR1 chromatin remodeling complex is a critical step in eukaryotic gene regulation. In Arabidopsis, sWRlc and H2A.Z have been shown to con- trol gene expression underlying development and environmental responses. Although they have been implicated in defense, the specific roles of the complex subunits and H2A.Z in immunity are not well under- stood. In this study, we analyzed the roles of the sWRlc subunits, PHOTOPERIOD-INDEPENDENT EARLY FLOWERINg1 （PIE1）, ACTIN-RELATED PROTEIN6 （ARP6）, and sWR1 COMPLEX 6 （sWC6）, as well as H2A.Z, in defense and gene regulation. We found that sWRlc components play different roles in resistance to different pathogens. Loss of PIE1 and sWC6 function as well as depletion of H2A.Z led to reduced basal resistance, while loss of ARP6 fucntion resulted in enhanced resistance. We found that mutations in PIE1 and sWC6 resulted in impaired effector-triggered immunity. Mutation in sWRlc components and H2A.Z also resulted in compromised jasmonic acid/ethylene-mediated immunity. genome-wide expres- sion analyses similarly reveal distinct roles for H2A.Z and sWRlc components in gene regulation, and s.g. gest a potential role for PIE1 in the regulation of the cross talk between defense s.g.aling pathways. Our data show that although they are part of the same complex, Arabidopsis sWRlc components could have non-redundant functions in plant immunity and gene regulation.

关键词： arabidopsis sWR1 chromatin remodeling H2A.Z immunity gene regulation

Hot n＇ Cold： Molecular s.g.atures of Domestication Bring Fresh Ins.g.ts into Environmental Adaptation

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Molecular Plant 2015年第10期8卷 1439-1441页

作者： Catherine gardener s. vinod Kumar Cell and Developmental Biology Department John Innes Centre Norwich NR4 7UH UK

Recent investigations of divergent rice genotypes have identified previously unknown molecular adaptations conferring heat and chilling tolerance in their corresponding local environments （Figure 1）. These studies s... 详细信息

关键词： domestication environmental adaptation

sm^(3+)induced structural phase transition,spectral,morphological,magnetic,dielectric and impedance properties of Ni_(0.1)Cu_(0.9)sm_(x)Fe_(2-x)O_(4) nanoferrites

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Journal of Rare Earths 2023年第11期41卷 1736-1745,I0003页

作者： K.Rajashekhar g.vinod K.Mahesh Kumar g.Harikishan Laxman Naik J Department of Physics University College of ScienceOsmania UniversityHyderabad500007TelanganaIndia Department of Physics Kamala Institute of Technology and ScienceHuzurabad505468TelanganaIndia Department of Physics CMR College of Engineering&TechnologyHyderabad501401TelanganaIndia

In the present study,rare earth samarium(sm^(3+))substituted Ni-Cu spinel ferrites with the composition of Ni_(0.1)Cu_(0.9)sm_(x)Fe_(2-x)O_(4)(0≤x≤0.05 in steps of 0.01)were synthesized by using the citrate induced sol-gel auto combustion *** ferrites'structural,optical,magnetic,and dielectric studies were carried out using X-ray diffraction(XRD),Fourier transform infrared spectroscopy(FTIR),field emission scanning electron microscopy(FEsEM),ultraviolet-visible(UV-vis),a vibrational sample magnetometer(VsM),and an LCR *** pure Ni-Cu ferrite exhibits a tetragonal structure owing to the presence of the John Tellar ion(Cu^(2+)).XRD patterns confirm that the tetragonal structure gradually transforms into the cubic spinel structure with samarium *** nano-scale structures of these ferrites were confirmed by the average crystallite size(10.11-20.99 nm)derived from the X-ray diffraction patterns,and grain size(42.60-83.36 nm)assessed from FEsEM *** existence of elements according to their chemical composition was verified by using energy dispersive X-ray(EDX)*** absorption bands(v_(1) and v_(2))detected in FTIR transmission spectra below the wavenumber of 600 cm^(-1)reveal the stretching vibrations of M-O bonds in the spinel structure at tetrahedral and octahedral *** band gap ene rgy obtained from UV absorption reveals the semiconducting nature of the *** high saturation magnetization(M_(s))is noticed at 15 K temperature for x=0.02 composition as 32.98 emu/g,while at 300 K for x=0.01composition as 27.61 emu/*** s.g.ested cation distribution is in good agreement with observed and predicted magnetic moment values at 300 *** expected behavior of ferrites reveals the observed dielectric constant,loss tangent,and ac-conductivity values in the frequency range of 20 Hz-20 ***-Cole plots confirm that the impedance contribution is attributed to grain boundaries.

关键词： Nanoferrites XRD Magnetic properties Dielectric properties Cole-cole plots Rare earths

sustainable Integrated Inventory Model for substitutable Deteriorating Items Considering Both Transport and Industry Carbon Emissions

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Journal of systems science and systems Engineering 2022年第3期31卷 267-287页

作者： Ranu singh vinod Kumar Mishra Department of Mathematics and scientific Computing Madan Mohan Malaviya University of TechnologyGorakhpur-273010U.P.India

sustainable integrated inventory management policy focuses on reducing the environmental impact of the manufacturing and transport *** study develops an integrated single-manufacturer single-buyer inventory model for substitutable deteriorating items considering transport and industry carbon *** article categorizes carbon emissions into two parts:direct and indirect *** also assume two mutually substitutable items,and substitution is considered on the buyer's *** one of the items is out of stock,the demand for that item can be partially satisfied by the stock of the other item;else,demand will be *** purpose of this study is to minimize the integrated cost of the supply chain with total carbon emissions produced by industry and transport sectors and to determine the optimal number of deliveries,order level and carbon emission quantity.A solution procedure is developed to find the optimal values of the *** experiments and sensitivity analyses are presented to demonstrate the proposed model.

关键词： Integrated inventory model sustainability deteriorating items substitutable items carbon emission