检索结果-南通市图书馆

Advancing Breast Cancer Diagnosis:The Development and Validation of the HERA-Net Model for Thermographic Analysis

Computers, Materials & Continua 2024年第12期81卷 3731-3760页

作者： s.Ramacharan Martin Margala Amjan shaik Prasun chakrabarti Tulika chakrabarti school of Computing and Informatics University of LouisianaLafayetteLA 70504USA Computer science and Engineering St.Peter’s Engineering CollegeHyderabad500100India Director Research and Dean International Affairs Sir Padampat Singhania UniversityUdaipur313601RajasthanIndia Department of Basic sciences Sir Padampat Singhania UniversityUdaipur313601RajasthanIndia

Breast cancer remains a significant global health concern,with early detection being crucial for effective treatment and improved survival *** study introduces HERA-Net(Hybrid Extraction and Recognition Architec-ture),an advanced hybrid model designed to enhance the diagnostic accuracy of breast cancer detection by leveraging both thermographic and ultrasound imaging *** HERA-Net model integrates powerful deep learning architectures,including VGG19,U-Net,GRU(Gated Recurrent Units),and ResNet-50,to capture multi-dimensional features that support robust image segmentation,feature extraction,and temporal *** thermographic imaging,a comprehensive dataset of 3534 infrared(IR)images from the DMR(Database for Mastology Research)was utilized,with images captured by the high-resolution FLIR sC-620 *** dataset was partitioned with 70%of images allocated to training,15%to validation,and 15%to testing,ensuring a balanced approach for model development and *** prepare the images,preprocessing steps included resizing,Contrast-Limited Adaptive Histogram Equalization(CLAHE)for enhanced contrast,bilateral filtering for noise reduction,and Non-Local Means(NLMs)filtering to refine structural *** metrics such as mean,variance,standard deviation,entropy,kurtosis,and skewness were extracted to provide a detailed analysis of thermal distribution across ***,the ultrasound dataset was processed to extract detailed anatomical features relevant to breast cancer *** involved grayscale conversion,bilateral filtering,and Multipurpose Beta Optimized Bihistogram Equalization(MBOBHE)for contrast enhancement,followed by segmentation using Geodesic Active *** ultrasound and thermographic datasets were subsequently fed into HERA-Net,where VGG19 and U-Net were applied for feature extraction and segmentation,GRU for temporal pattern recognition,and ResNet-50 for *** performance assessme

关键词： Cancer breast cancer detection sensitivity deep learning accuracy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydro-chemical study of the evolution of interstellar pre-biotic molecules during the collapse of molecular clouds

引用

Research in Astronomy and Astrophysics 2012年第12期12卷 1613-1624页

作者： Liton Majumdar Ankan Das sandip K. chakrabarti sonali chakrabarti Indian Centre for space Physics Chalantika 43Garia Station RoadKolkata-700084India s.N.Bose National Centre for Basic sciences Salt LakeKolkata-700098India Maharaja Manindra Chandra College 20 Ramakanto Bose StreetKolkata-700003India

One of the stumbling blocks for studying the evolution of interstellar molecules is the lack of adequate knowledge about the rate coefficients of various reactions which take place in the interstellar medium and molecular *** theoretical models of rate coefficients do exist in the literature for computing abundances of complex pre-biotic *** far these have been used to study the abundances of these molecules in ***,in order to obtain more accurate final compositions in these media,we have calculated the rate coefficients for the formation of some of the most important interstellar pre-biotic molecules by using quantum chemical *** use these rates inside our hydro-chemical model to examine the chemical evolution and final abundances of pre-biotic species during the collapsing phase of a *** find that a significant amount of various pre-biotic molecules could be produced during the collapse phase of a *** thoroughly study the formation of these molecules via successive neutral-neutral and radical-radical/radicalmolecular *** present the time evolution of the chemical species with an emphasis on how the production of these molecules varies with the depth of a cloud. We compare the formation of adenine in interstellar space using our rate-coefficients and using those obtained from existing theoretical *** routes of the pre-biotic molecules are found to be highly dependent on the abundances of the reactive species and the rate coefficients involved in the *** presence of grains strongly affects the abundances of the gas phase *** also carry out a comparative study between different pathways available for the synthesis of adenine,alanine, glycine and other molecules considered in our *** the huge abundances of the neutral reactive species,production of adenine is found to be strongly dominated by the radical-radical/radical-molecular reaction *** all the reactio

关键词： IsM clouds-astrochemistry-stars formation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

DNA Damage Caused By Pesticide-contaminated soil

引用

Biomedical and Environmental sciences 2006年第6期19卷 427-431页

作者： K. KRIsHNAMURTHI s. sARAVANA DEVI T. chakrabarti Environmental Biotechnology Division National Environmental Engineering Research Institute (NEERI)Nehru MargNagpur-440020India

Objective To determine the DNA damaging potential and the genotoxicity of individual compounds in pesticide contaminated soil. Methods In the present study, DNA damaging potential of pesticide-contaminated soil and the genotoxicity of individual compounds present in the soil were assessed using fluofimetdc analysis of DNA unwinding assay. Results The contaminated soil sample showed 79% （P〈0.001） of DNA strand break, whereas technical grade of major catbaryl and α-naphthol constituents of the contaminated soil showed 64% （P〈0.01） and 60% （P〈0.02） damage respectively. Conclusion Our results indicate that the toxicity caused by contaminated soil is mainly due to carbatyl and α -napthol, which are the major constituents of the soil sample analyzed by CrC-Ms.

关键词： Carbaryl Contaminated soil DNA damage FADU- Fluorimetric analysis of DNA unwinding assay Genotoxicity α-Napthol and pesticide

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Genotoxicity of Pesticide Waste Contaminated soil and Its Leachate

引用

Biomedical and Environmental sciences 2004年第3期17卷 257-265页

作者： s.D.sIVANEsAN K.KRIsHNAMURTHI s.D.WACHAsUNDER T.chakrabarti Environmental Biotechnology Division Environmental Biotechnology DivisionInstrumentation Division National Environmental Engineering Research Institute Nehru Marg Nagpur-440 020 IndiaEnvironmental Biotechnology Division

Objective Improper land disposal of hazardous waste can result in leaching of hazardous constituents which may contaminate ground and surface water leading to adverse impact on human health and environment consequences. The present study utilized mammalian cell culture for the genotoxicity assessment of waste and its leachate. Methods Genotoxic potential and chemical analysis of pesticide derived tarry waste contaminated soil extract and its leachate was assessed using in vitro human lymphocyte cultures and GC-Ms. Results The investigation revealed that the soil extract could cause significant to highly significant genotoxicity in the form of DNA strand break at 25 mL (Psomal aberration at 25 mL (Pse significant DNA strand break and chromosomal aberration only at 100 mL and 200 mL (Pse levels. Conclusion The genotoxicity observed is attributed to carbaril and tetra methyl naphthyl carbamate, the major ingredients of the extracts, as revealed by GC-Ms.

关键词： Genotoxicity soil extract Leachate DNA strand break Chromosomal aberration Gas chromatography mass spectrometery (GC-Ms) Fluorimetric analysis of DNA unwinding assay (FADU)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Protective Effect of Distillate and Redistillate of Cow’s Urine in Human Polymorphonuclear Leukocytes Challenged With Established Genotoxic Chemicals

引用

Biomedical and Environmental sciences 2004年第3期17卷 247-256页

作者： K.KRIsHNAMURTHI DIPANWITA DUTTA s.D.sIVANEsAN T. chakrabarti Environmental Biotechnology Division National Environmental Engineering Research Institute Nehru Marg Nagpur-440 020 INDIA

Objective From the ancient period cow’urine has been used as a medicine. In Veda, cow’urine was compared to the nectar. In susrut, several medicinal properties of cow’ urine have been mentioned and are known to cause weight loss, reversal of certain cardiac and kidney problems, indigestion, stomach ache, edema, etc. However, the literature and scripture did not mention the antigenotoxic properties of cow’urine. Methods In the present investigation, the antigenotoxic/ antioxidant properties of cow’ urine distillate and redistillate were studied in vitro. The antioxidant status and volatile fatty acid levels were determined. Actinomycin-D (0.1ol/L) and hydrogen peroxide (150 mol/L) were used for inducing DNA strand break with 0.1% DMsO as negative control. Dose for the antigenotoxic effect of cow’ urine was chosen from the dose response study carried out earlier. Results Both actinomycin-D and H2O2 caused statistically significant DNA unwinding of 80% & 75% respectively (Ps revealed by fluorimetric analysis of DNA unwinding (FADU), and the damage could be protected with the redistilled cow urine distillate (1, 50 & 100 ) in simultaneous treatment with genotoxic chemicals. Conclusion The redistillate of cowurine was found to possess total antioxidant status of around 2.6 mmol, contributed mainly by volatile fatty acids (1500 mg/L) as revealed by the GC-Ms studies. These fatty acids and other antioxidants might cause the observed protective effects.

关键词： Ammonia Antioxidants Cow urine distillate Cow urine redistillate Human polymorphonuclear leukocytes(PMNL) DNA damage Fluorimetric analysis of DNA unwinding(FADU) Gas chromatography mass spectrometer(GC-Ms) Genotoxicity Volatile fatt

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Anticlastogenic Effect of Redistilled Cow's Urine Distillate in Human Peripheral Lymphocytes Challenged With Manganese Dioxide and Hexavalent Chromium

引用

Biomedical and Environmental sciences 2006年第6期19卷 487-494页

作者： DIPANWITA DUTTA s. sARAVANA DEVI K. KRIsHNAMURTHI T. chakrabarti Environmental Biotechnology Division National Environmental Engineering Research Institute (NEERI)Nehru MargNagpur-440020INDIA

Objective To study the anticlastogenic effect of redistilled cow＇s urine distillate （RCUD） in human peripheral lymphocytes （HLC） challenged with manganese dioxide and hexavalent chromium. Methods The anticlastogenic activity of redistilled cow＇s urine distillate was studied in human polymorphonuclear leukocytes （HPNLs） and human peripheral lymphocytes in vitro challenged with manganese dioxide and hexavalent chromium as established genotoxicants and clastogens which could cause induction of DNA strand break, chromosomal aberration and micronucleus. Three different levels of RCUD： 1 μL/mL, 50 μL/mL and 100 μL/mL, were used in the study. Results Manganese dioxide and hexavalent chromium caused statistically significant DNA strand break, chromosomal aberration and micronucleus formation, which could be protected by redisfilled cow＇s urine distillate. Conclusion The redistilled cow＇s urine distillate posseses strong anfigenotoxic and antielastogenic properties against HPNLs and HLC treated with Cr^＋6 and MnO2. This property is mainly due to the antioxidants present in RCUD.

关键词： Redistilled cow's urine distillate (RCUD) DNA strand break Clastogenicity Chromosomal aberration Micronuclei Hexavalent chromium and manganese dioxide

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bipolar disorder in the International Classification of Diseases-Eleventh version:A review of the changes,their basis,and usefulness

引用

World Journal of Psychiatry 2022年第12期12卷 1335-1355页

作者： subho chakrabarti Department of Psychiatry Postgraduate Institute of Medical Education and Research(PGIMER)Chandigarh 160012UTIndia

The World Health Organization’s 11^(th)revision of the International Classification of Diseases(ICD-11)including the chapter on mental disorders has come into effect this *** review focuses on the“Bipolar or Related Disorders”section of the ICD-11 *** describes the benchmarks for the new version,particularly the foremost principle of clinical *** alterations made to the diagnosis of bipolar disorder(BD)are evaluated on their scientific basis and clinical *** change in the diagnostic requirements for manic and hypomanic episodes has been much *** the current criteria have achieved an optimum balance between sensitivity and specificity is still not *** ICD-11 definition of depressive episodes is substantially different,but the lack of empirical support for the changes has meant that the reliability and utility of bipolar depression are relatively *** the Diagnostic and statistical Manual of Mental Disorders,5th edition(DsM-5),the ICD-11 has retained the category of mixed *** the concept of mixed episodes in the ICD-11 is not perfect,it appears to be more inclusive than the DsM-5 ***,there are some uncertainties about the guidelines for the subtypes of BD and cyclothymic *** initial results on the reliability and clinical utility of BD are promising,but the newly created diagnostic categories also appear to have some *** further improvement and research are needed,the focus should now be on facing the challenges of implementation,dissemination,and education and training in the use of these guidelines.

关键词： ICD-11 guidelines Bipolar disorder Utility Reliability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geochemistry of the Palaeo–Mesoproterozoic Tadpatri shales,Cuddapah basin, India: implications on provenance,paleoweathering and paleoredox conditions

引用

Acta Geochimica 2018年第5期37卷 715-733页

作者： Rahul Mitra Gopal chakrabarti Debasish shome Department of Geological sciences Jadavpur University Education Directorate Government of West Bengal

The Palaeo–Mesoproterozoic Tadapatri formation of the Cuddapah basin is comprised of clastic sedimentary rocks with minor carbonates and mafic–ultramafic sill bodies. Geochemistry of the shale is used to study the provenance, paleoweathering and paleoredox conditions of this Tadpatri formation in order to better understand the development of the Cuddapah basin during Palaeo–Mesoproterozoic time. The higher CIA(average 74.39), PIA(average 85.94) and CIW(average 87.59) values of the Tadpatri shales suggest intensely weathered *** Al2_ O_3/TiO_2(average 30.78) and LREE/HREE ratio(average 8.80) with negative europium anomaly indicate derivation of the clastic sediments from a felsic source rock. The geochemical parameters like U, U/Th, Cu/Zn,Ni/Co, V/Cr ratios reveal that the Tadpatri shales are mainly deposited in an oxic condition.

关键词： Tadpatri Provenance Paleoweathering Paleoredox Geochemistry

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analytical modeling and ATLAs simulation for a homojunction LED in the mid-infrared spectral region

引用

Optoelectronics Letters 2009年第6期5卷 417-421页

作者： sanjeev P. chakrabarti Department of Electronics and Instrumentation Engineering Institute of Engineering and TechnologyMJP Rohilkhand University Centre for Research in Microelectronics(CRME) Department of Electronics EngineeringInstitute of TechnologyBanaras Hindu University

A generic analytical model and the ATLAs simulation of a homojunction light emitting diode(LED) based on p+-InAs0.91sb0.09/n0-InAs0.91sb0.09/n+-InAs0.91sb0.09 materials grown on lattice matched p+-Gasb substrate are *** LED is suitable for use as source in the optical absorption gas spectroscopy in the mid-infrared spectral region at 300 *** various electro-optical properties of the homojunction LED are evaluated using analytical techniques and ATLAs device simulation *** current-voltage characteristics of the structure are computed analytically and simulated,and the results are found to be in good *** output power of the homojunction LED is estimated as a function of bias current under high carrier injection and compared with the reported experimental results.

关键词：发光二极管灯 ATLAs 同质结红外谱仿真功率LED 高技术条件建模

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Genotoxic Effects of PAH Containing sludge Extracts in Chinese Hamster Ovary Cell Cultures

引用

Biomedical and Environmental sciences 2003年第1期16卷 68-82页

作者： K.KRIsHNAMURTHI FONTDEVI T.chakrabarti Environmental Biotechnology Division National Environmental Engineering Research InstituteNehru MargNagpur-440020IndiaEnvironmental Biotechnology DivisionNational Environmental Engineering Research InstituteNehru MargNagpur-440020IndiaEnvironmental Biotechnology DivisionNational Environmental Engineering Research InstituteNehru MargNagpur-440020India

Objective Many studies have been conducted in order to evaluate the genotoxicity of chemicals and waste materials, which utilized in vivo test protocols. The use of animals for routine toxicity testing is now questioned by a growing segment of society. Methods Keeping the above fact in mind, we have conducted in the present study the genotoxicity evaluation of oily sludge samples generated from a petroleum refinery and petrochemical industry and ETP sludge from petroleum refinery using DNA damage, chromosomal aberration, p53 protein induction and apoptosis in short term in vitro mammalian Chinese Hamster Ovary cell cultures. Results It is evident from the results that the oily sludge compounds derived from petroleum refinery and petrochemical industry could cause DNA damage, chromosomal aberration, p53 protein accumulation and apoptotic cell death on exposure to oily sludge extracts in the presence of metabolic activation system (s-9 mix), however, ETP sludge extract could not cause significant genotoxicity in comparison to oily sludge extract and negative control. Conclusion The effect may be attributed to polycyclic aromatic hydrocarbons present in the samples as evidenced from GC-Ms.

关键词： DNA damage Chromosomal aberration p53 protein induction Apoptosis Genotoxicity Polycyclic aromatic hydrocarbons (PAHs) Gas chromatograph mass spectrometer (GC-Ms)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：