DNA Damage Caused By Pesticide-contaminated Soil

作     者：K. KRISHNAMURTHI S. SARAVANA DEVI T. CHAKRABARTI 

作者机构：Environmental Biotechnology DivisionNational Environmental Engineering Research Institute (NEERI)Nehru MargNagpur-440020India 

出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)

年 卷 期：2006年第19卷第6期

页      面：427-431页

核心收录：

学科分类：12[管理学] 1204[管理学-公共管理] 082803[工学-农业生物环境与能源工程] 08[工学] 0828[工学-农业工程] 120405[管理学-土地资源管理] 

基　　金：Dr. Sukumar DEV0TTA  Director NEERI isgratefully acknowledged for providing the necessary facilities for this investigation  his time-to-time suggestions and encouragement 

主　　题：Carbaryl Contaminated soil DNA damage FADU- Fluorimetric analysis of DNA unwinding assay Genotoxicity α-Napthol and pesticide 

摘      要：Objective To determine the DNA damaging potential and the genotoxicity of individual compounds in pesticide contaminated soil. Methods In the present study, DNA damaging potential of pesticide-contaminated soil and the genotoxicity of individual compounds present in the soil were assessed using fluofimetdc analysis of DNA unwinding assay. Results The contaminated soil sample showed 79% （P〈0.001） of DNA strand break, whereas technical grade of major catbaryl and α-naphthol constituents of the contaminated soil showed 64% （P〈0.01） and 60% （P〈0.02） damage respectively. Conclusion Our results indicate that the toxicity caused by contaminated soil is mainly due to carbatyl and α -napthol, which are the major constituents of the soil sample analyzed by CrC-MS.