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Modelling of electric vehicle charging station and controlled by fuzzy logic controller with different modes of operation

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Journal of Control and Decision 2023年第1期10卷 26-39页

作者： s.C.Vijay Kumar K.Karunanithi s.p.raja s.Ramesh p.Chandrasekar R.Obulupathy vel tech rangarajan dr.sagunthala r&d institute of science and technology chennaitamil naduindia school of computer science and engineering vellore institute of technologyvelloretamil naduindia

The main objective of implementing charging stations is to ensure the good charging to theElectric Vehicles by using a solar pV array which is interconnected to the battery energy storagesystems. The charging station regulates the supply voltage and frequency without the use of amechanical speed governor. It also assures that energy gained from grid or by the DG set willhave the unity power factor (UpF) when the load is nonlinear. Besides this, the point of CommonCoupling (pCC) voltage is synchronised with the grid/generator voltage in order to providecontinuous charging. In order to increase the optimal efficiency of the charging stations, thecharging stations will perform the active/reactive power transfer from the vehicle to grid, vehicleto house and vehicle to vehicle (V2V) power transfer. The operational experiment of the chargingstation is simulated and verified by using MATLAB/sIMULINK.

关键词： Electric vehicle charging station solar photo-voltaic generation energy transfer diesel-generator set fuzzy logic controller total harmonic distortion

Unlocking hypoglycemia–associated brain microvascular dysfunction:critical insights from proteomic analysis

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Neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： siva s.V.p.sakamuri Anil sakamuri Department of Chemistry Auburn University at MontgomeryMontgomeryALUSA Vascular Biology Center and Department of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemia-a critical complication linked to worsened brain function in diabetic subjects:Hypoglycemia is characterized by a decline in circulatory glucose levels below sta nda rd physiological *** hypoglycemia,classified as level 1 hypoglycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hypoglycemia,denoted by blood glucose levels less than 54 mg/dL,poses a life-threatening risk if left *** with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms.

关键词： impaired intake critical

Unsupervised neural networks for solving Troesch＇s problem

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Chinese physics B 2014年第1期23卷 546-556页

作者： Muhammad Asif Zahoor raja Muhammad.asif@ciit-attock.edu.pk rasifzahoor@*** []Department of Electrical Engineering COMSATS Institute of Information Technology Attock Campus Attock Pakistan

In this study, stochastic computational intelligence techniques are presented for the solution of Troesch's boundary value problem. The proposed stochastic solvers use the competency of a feed-forward artificial neural network for mathematical modeling of the problem in an unsupervised manner, whereas the learning of unknown parameters is made with local and global optimization methods as well as their combinations. Genetic algorithm (GA) and pattern search (ps) techniques are used as the global search methods and the interior point method (IpM) is used for an efficient local search. The combination of techniques like GA hybridized with IpM (GA-IpM) and ps hybridized with IpM (ps-IpM) are also applied to solve different forms of the equation. A comparison of the proposed results obtained from GA, ps, IpM, ps-IpM and GA-IpM has been made with the standard solutions including well known analytic techniques of the Adomian decomposition method, the variational iterational method and the homotopy perturbation method. The reliability and effectiveness of the proposed schemes, in term of accuracy and convergence, are evaluated from the results of statistical analysis based on sufficiently large independent runs. [ABsTRACT FROM AUTHOR]

关键词： GENETIC algorithms COMBINATORIAL optimization EVOLUTIONARY algorithms EVOLUTIONARY computation pHYsICs

Optimization of assembly line balancing using genetic algorithm

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Journal of Central south University 2015年第10期22卷 3957-3969页

作者： N.Barathwaj p.raja s.Gokulraj school of Mechanical Engineering SASTRA University Rane (Madras) Ltd. Deputy Manager (Manufacturing Engineering System Design Department)

In a manufacturing industry, mixed model assembly line(MMAL) is preferred in order to meet the variety in product demand. MMAL balancing helps in assembling products with similar characteristics in a random fashion. The objective of this work aims in reducing the number of workstations, work load index between stations and within each station. As manual contribution of workers in final assembly line is more, ergonomics is taken as an additional objective function. Ergonomic risk level of a workstation is evaluated using a parameter called accumulated risk posture(ARp), which is calculated using rapid upper limb assessment(RULA) check sheet. This work is based on the case study of an MMAL problem in Rane(Madras) Ltd.(India), in which a problem based genetic algorithm(GA) has been proposed to minimize the mentioned objectives. The working of the genetic operators such as selection, crossover and mutation has been modified with respect to the addressed MMAL problem. The results show that there is a significant impact over productivity and the process time of the final assembled product, i.e., the rate of production is increased by 39.5% and the assembly time for one particular model is reduced to 13 min from existing 18 min. Also, the space required using the proposed assembly line is only 200 m2 against existing 350 m2. Further, the algorithm helps in reducing workers fatigue(i.e., ergonomic friendly).

关键词： optimization line balancing genetic algorithm product family assembly line

Revisiting cerebral endothelial cells in Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2911-2912页

作者： Amira s.Hanafy Department of Neurosurgery University Hospital BonnBonnGermany

Alzheimer’s disease(AD)is the most common neurodegenerative disorder characterized by slow and progressive decline of cognitive and memory *** only approximately 5%of the cases,AD is familial,as often predisposed by genetic mutations(Hoogmartens et al.,2021),while sporadic AD accounts for approximately 95%of the *** amyloid cascade hypothesis is one of the fundamental hypotheses put out to explain AD pathogenesis as dysregulated homeostasis of amyloid-β(Aβ)peptides that leads to the accumulation of Aβplaques in the parenchyma,an anatomical hallmark of AD.

关键词： Alzheimer Aβ cerebral

Emerging structures and dynamic mechanisms ofγ-secretase for Alzheimer’s disease

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Neural Regeneration Research 2025年第1期20卷 174-180页

作者： Yinglong Miao Michael s.Wolfe Computational Medicine program and Department of pharmacology University of North Carolina–Chapel HillChapel HillNCUSA Department of Medicinal Chemistry University of KansasLawrenceKSUSA

γ-secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the Notch family of cell-surface *** inγ-secretase and amyloid precursor protein lead to early-onset familial Alzheimer’s disease.γ-secretase has thus served as a critical drug target for treating familial Alzheimer’s disease and the more common late-onset Alzheimer’s disease as ***,critical gaps remain in understanding the mechanisms of processive proteolysis of substrates,the effects of familial Alzheimer’s disease mutations,and allosteric modulation of substrate cleavage byγ-*** this review,we focus on recent studies of structural dynamic mechanisms ofγ-*** mechanisms,including the“Fit-stay-Trim,”“sliding-Unwinding,”and“Tilting-Unwinding,”have been proposed for substrate proteolysis of amyloid precursor protein byγ-secretase based on all-atom molecular dynamics *** an incorrect registry of the Notch1 substrate was identified in the cryo-electron microscopy structure of Notch1-boundγ-secretase,molecular dynamics simulations on a resolved model of Notch1-boundγ-secretase that was reconstructed using the amyloid precursor protein-boundγ-secretase as a template successfully capturedγ-secretase activation for proper cleavages of both wildtype and mutant Notch,being consistent with biochemical experimental *** approach could be potentially applied to decipher the processing mechanisms of various substrates byγ-*** addition,controversy over the effects of familial Alzheimer’s disease mutations,particularly the issue of whether they stabilize or destabilizeγ-secretase-substrate complexes,is ***,an outlook is provided for future studies ofγ-secretase,including pathways of substrate binding and product release,effects of modulators on familial Alzheimer’s disease mutations

关键词： Alzheimer’s disease amyloid precursor protein cryo-EM structures drug design intramembrane proteolysis molecular dynamics Notch

16s rDNA-Based phylogeny of Non-symbiotic Bacteria of Entomopathogenic Nematodes from Infected Insect Cadavers

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Genomics, proteomics & Bioinformatics 2011年第3期9卷 104-112页

作者： M. Razia R. Karthik raja K. padmanaban p. Chellapandi s. sivaramakrishnan Department of Biotechnology school of Life sciences Bharathidasan University Tiruchirappalli 620024 Tamil Nadu India Department of Bioinformatics school of Life sciences Bharathidasan University Tiruchirappalli 620024 Tamil Nadu India

Using 16s rDNA gene sequencing technique, three different species of non-symbiotic bacteria of entomopathogenie nematodes （EpNs）（steinernema sp. and Heterorhabditis sp.） were isolated and identified from infected insect cadavers （Galleria mellonella larvae） after 48-hour post infections. sequence similarity analysis revealed that the strains sRK3, sRK4 and sRK5 belong to Ochrobactrum cytisi, schineria larvae and Ochrobactrum anthropi, respectively. The isolates O. anthropi and s. larvae were found to be associated with Heterorhabditis indica strains BDU-17 and Yer-136, respectively, whereas O. cytisi was associated with steinernema siamkayai strain BDU-87. phenotypically, temporal EpN bacteria were fairly related to symbiotic EpN bacteria （photorhabdus and Xenorhabdus genera）. The strains sRK3 and sRK5 were phylogeographically similar to several non-symbionts and contaminated EpN bacteria isolated in Germany （LMG3311T） and China （X-14）, while the strain sRK4 was identical to the isolates of s. larvae （L1/57, L1/58, L1/68 and L2/11） from Wohlfahrtia magnifica in Hungary. The result was further confirmed by RNA secondary structure and minimum energy calculations of aligned sequences. This study suggested that the non-symbionts of these nematodes are phylogeographicaily diverged in some extent due to phase variation. Therefore, these strains are not host-dependent, but environment-specific isolates.

关键词： entomopathogen schineria Ochrobactrum non-symbionts phylogenetics phase variation

Complementary roles of glial cells in generating region-specific neuroinflammatory responses and phagocytosis in parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2917-2918页

作者： Leyre Ayerra Maria s.Aymerich Universidad de Navarra Facultad de CienciasDepartamento de Bioquímica y GenéticaPamplonaSpain CIMA-Universidad de Navarra PamplonaSpain IdisNA Instituto de Investigación Sanitaria de NavarraPamplonaSpain

Neuroinflammation is associated with parkinson’s disease:Reactive gliosis and neuroinflammation are hallmarks of parkinson’s disease(pD),a multisystem neurodegenerative disorder characterized by a progressive loss of dopaminergic *** has long been considered a mere consequence of neuronal loss,but whether it promotes pD or is a key player in disease progression remains to be *** leukocyte antigen.

关键词： inflammation leukocyte generating

Threshold Chloride Concentration for passivity Breakdown of Mg-Zn-Gd-Nd-Zr Alloy (EV31A) in Basic solution

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Acta Metallurgica sinica(English Letters) 2017年第4期30卷 352-366页

作者： Jakraphan Ninlachart Krishnan s. raja Chemical and Materials Engineering University of IdahoMoscow ID 83844-1021 USA

Mg-Zn-Gd-Nd-Zr alloy （EV31A） is a heat-treatable magnesium （Mg） cast alloy that can be used up to 200 ℃ for automobile and aerospace applications. This alloy has excellent mechanical properties （ultimate tensile strength： 280 Mpa at room temperature, and -230 Mpa at 200 ℃） and improved corrosion resistance. Electrochemical corrosion studies were conducted on this alloy under different heat treatment conditions in 0.1 M NaOH solution with the addition of 0-1000 ppm of chloride. The alloy showed excellent passivity in the 0.1 M NaOH solution. The passive potential range typically extended to more than 1.2 VAg/AgCl. The transpassive potential was observed to be dependent on heat treatment condition of the alloy. More than 80 ppm of chloride was required to induce passivity breakdown in any heat treatment condition. peak aging at 200 ℃ for 16 h imparted better resistance for localized corrosion than other heat-treated con- ditions. The alloy in the as-received condition showed the highest passivation kinetics due to its smaller grain size that possibly increased the diffusion of reactive elements to form protective oxide. The passive film of the EV31A alloy showed n-type semiconductivity with a charge carrier density of - 2 × 10^21 cm^- 3 with no chloride addition. The charge carrier density increased with chloride addition in the electrolyte which could be correlated with the susceptibility to localized corrosion.

关键词： Magnesium alloy Corrosion passivation Chloride