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statistical Modeling studies of Iron Recovery from Red Mud Using Thermal Plasma

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Plasma science and Technology 2013年第5期15卷 459-464页

作者： swagat s. RATH Archana PANY k. JAYAsANkAR Ajit k. mitra C. sATIsH kUMAR Partha s. MUkHERJEE Barada k. MIsHRA Institute of Minerals and Materials Technology (CsIR) Vedanta Alumina Limited Lanjigarh

Optimization studies of plasma smelting of red mud were carried out. Reduction of the dried red mud fines was done in an extended arc plasma reactor to recover the pig iron. Lime grit and low ash metallurgical （LAM） coke were used as the flux and reductant, respectively. 2level factorial design was used to study the influence of all parameters on the responses. Response surface modeling was done with the data obtained from statistically designed experiments. Metal recovery at optimum parameters was found to be 79.52%.

关键词： plasma response surface modeling red mud design of experiments optimiza-tion

Understanding activity of butyrate at a cellular level

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Neural Regeneration Research 2025年第8期20卷 2323-2324页

作者： Prapti Chakraborty Angela s.Laird Macquarie University Motor Neuron Disease Research Centre Macquarie Medical SchoolFaculty of MedicineHealth and Human SciencesMacquarie UniversitySydneyAustralia

Butyrate is a short-chain fatty acid of four carbons in length that is a by-product produced by the microbial fermentation of dietary fiber and undigested carbohydrates within the *** the years,butyrate has attracted ... 详细信息

关键词： carbons butyrate fiber

Microglial dysfunction and genetic risk for neurodegenerative disease

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Neural Regeneration Research 2025年第5期20卷 1401-1402页

作者： Debra s.MacDonald Jay Penney Department of Biomedical sciences AVCUniversity of Prince Edward IslandCharlottetownPECanada

Neurodegenerative disorders such as Alzheimer's and Parkinson's diseases a re increasing in prevalence as world populations *** tremendous progress has been made,our understanding of the mechanisms that underlie the development of these diseases remains far from com *** troubling,despite the growing emotional and financial toll being to ken by neurodegenerative disorders,existing treatment options are limited almost exclusively to those that help manage symptoms but that lack the ability to alter the progression of the disease(Liu et al.,2022).

关键词： degenerative diseases

Bioreactor control systems in the biopharmaceutical industry:a critical perspective

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systems Microbiology and Biomanufacturing 2022年第1期2卷 91-112页

作者： sagnik mitra Ganti s.Murthy Department of Biosciences and Biomedical Engineering Indian Institute of Technology IndoreIndore 453552India

Industrial-scale bioprocessing underpins much of the production of pharmaceuticals,nutraceuticals,food,and beverage processing industries of the modern *** proftability of these processes increasingly leverages the economies of scale and scope that are critically dependent on the product yields,titers,and *** of the processes are controlled using classical control approaches and represent over 90%of the industrial controls used in bioprocessing ***,with the advances in the production processes,especially in the biopharmaceutical and nutraceutical industries,monitoring and control of bioprocesses such as fermentations with GMO organisms,and downstream processing has become increasingly complex and the inadequacies of the classical and some of the modern control systems techniques is becoming ***,with increasing research complexity,nonlinearity,and digitization in process,there has been a critical need for advanced process control that is more efective,and easier process intensifcation and product yield(both by quality and quantity)can be *** this review,industrial aspects of a process and automation along with various commercial control strategies have been extensively discussed to give an insight into the future prospects of industrial development and possible new strategies for process control and automation with a special focus on the biopharmaceutical industry.

关键词： Bioreactor control systems Digitization Advanced process control Industrial automation single-use technology Biopharmaceuticals

In silico comparative structural and compositional analysis of glycoproteins of RsV to study the nature of stability and transmissibility of RsV A

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systems Microbiology and Biomanufacturing 2023年第2期3卷 312-327页

作者： Debanjan mitra Pradeep k.Das Mohapatra Department of Microbiology Raiganj UniversityRaiganjWBIndia

The current scenario of COVID-19 makes us to think about the devastating diseases that kill so many people every *** of viral proteins contributes many things that are utterly useful in the evolution of therapeutic drugs and *** this study,sequence and structure of fusion glycoproteins and major surface glycoproteins of respiratory syncytial virus(RsV)were analysed to reveal the stability and transmission *** A has the highest abundance of aromatic *** kyte–Doolittle scale indicates the hydrophilic nature of RsV A protein which leads to the higher transmission rate of this ***-protein interactions such as carbonyl interactions,cation-pi,and salt bridges were shown to be greater in RsV A compared to RsV B,which might lead to improved *** study discovered the presence of a network aromatic–sulphur interaction in viral *** of ligand binding pocket of RsV proteins indicated that drugs are performing better on RsV B than RsV *** was also shown that increasing the number of tunnels in RsV A proteins boosts catalytic *** study will be helpful in drug discovery and vaccine development.

关键词： Respiratory syncytial virus stability Intra-protein interactions Tunnels Drug discovery

Novel Hydrodynamic Analysis Towards Capabilities Improvement of Bio-inspired Underwater Vehicles Using Momentum Redistribution Method

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Journal of Bionic Engineering 2022年第2期19卷 314-330页

作者： Rakesh Rayapureddi santanu mitra Mechanical Engineering Department Shiv Nadar UniversityDelhi-NCR 201314NoidaIndia

This paper presents an efficient and versatile OpenFOAM(Open-source Field Operation And Manipulation)-based numerical solver for fully resolved simulations that can handle any rigid and deforming bodies moving in the *** algorithm used for solving Fluid-structure Interactions(FsI)involving the immersed structure with changeable shapes is based on the momentum redistribution *** present approach excludes the need to solve elastic equations,obtain high-accuracy predictions of the flow field and provide a rigorous basis for implementing the Immersed Boundary Method(IBM).The OpenFOAM implementation of the algorithm is discussed along with the design methodology for developing bio-inspired underwater vehicles using the present *** computational results are validated with the experimental observations of the two-dimensional and three-dimensional anguilliform swimmer case *** study further extended to the three-dimensional hydrodynamics of a bioinspired,self-propelling manta *** motion of the body is specified a priori according to the reported experimental *** results quantify the vortex formation and shedding processes and enable the identification of the portions of the body responsible for the majority of *** body accelerates from rest to an asymptotic mean forward velocity of 0.2 ms^(-1)in almost 5 s,consistent with experimental *** is observed that the developed computational model is capable of performing any motion simulation and manoeuvrability analysis,which are critical for the designers to develop novel unmanned underwater vehicles.

关键词： Momentum redistribution method OpenFOAM Fluid-structure Interaction(FsI) Immersed Boundary Method(IBM) Anguilliform swimming Manta bot

A survey of density based clustering algorithms

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Frontiers of Computer science 2021年第1期15卷 139-165页

作者： Panthadeep BHATTACHARJEE Pinaki mitra Department of Computer science and Engineering Indian Institute of TechnologyGuwahati 781039India

Density based clustering algorithms(DBCLAs)rely on the notion of density to identify clusters of arbitrary shapes,sizes with varying *** surveys on DB-CLAs cover only a selected set of *** surveys fail to provide an extensive information about a variety of DBCLAs proposed till date including a taxonomy of the *** this paper we present a comprehensive survey of various DB-CLAs over last two decades along with their *** group the DBCLAs in each of the four categories:density definition,parameter sensitivity,execution mode and nature of*data and further divide them into various classes under each of these *** addition,we compare the DBCLAs through their common features and variations in citation and conceptual *** identify various application areas of DBCLAs in domains such as astronomy,earth sciences,molecular biology,geography,*** survey also identifies probable future directions of DBCLAs where involvement of density based methods may lead to favorable results.

关键词： clustering density based clustering survey classification common properties applications

Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 193-208页

作者： k.MUHAMMAD M.sARFRAZ Department of Humanities and sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Mathematics Quaid-i-Azam University

This article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. The space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invoking magnetohydrodynamic(MHD) effects. Further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. The problem is solved via NDsolve in MATHEMATICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and skin *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. The thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

关键词： convective boundary condition Darcy-Forchheimer medium hybrid nanofluid Joule heating magnetohydrodynamic (MHD) numerical solution squeezing flow regression analysis O361 O175.2

Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

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Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor Cilleros-Mañé Laia Just-Borràs Marta Balanyà-segura Aleksandra Polishchuk Laura Nadal Marta Tomàs Carolina silvera-simón Manel M.santafé Maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PkA and PkC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PkA/PkC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB