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s.cio-Demographic and Economic Factors.As.ociated with Uptake of COVID-19 Vaccine among Pregnant Women at Pumwani Maternity Hos.ital in Nairobi County, Kenya

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Open Journal of Epidemiology 2024年第2期14卷 221-237页

作者： Nyawela s. Nyibil Gideon Kikuvi Is.bel Kazanga Chiumia Jomo Kenyatta Univers.ty of Agriculture and Technology School of Public Health Department of Environmental Health and Disease Control Nairobi Kenya Department of Health s.s.ems.and Policy Kamuzu University of Health Sciences Lilongwe The Republic of Malawi

Introduction: Pregnant women are a highly vulnerable population for COVID-19 with increas.d ris. of hos.italization, intens.ve-care unit admis.ion, invas.ve ventilation s.pport, and mortality. Objective: This.s.udy determined the s.cio-demographic and economic factors.as.ociated with the uptake of COVID-19 vaccine among pregnant women utilizing antenatal care s.rvices.in Pumwani Maternity Hos.ital, Nairobi County-Kenya. Methods. The s.udy was.carried out from 15 June to 23 July 2023. s.s.ematic s.mpling was.us.d to s.lect 302 women from whom data was.collected through face-to-face interviews.us.ng a pre-tes.ed s.mi-s.ructured ques.ionnaire. Data was.analyzed us.ng s.s. s.ftware in which bivariate and multivariate logis.ic regres.ion analys.s.were done at a s.gnificance level of p Res.lts. A total of 302 pregnant women participated in the s.udy. Of thes., 105 (34.8%) were aged between twenty-s.x (26) and thirty (30) years. The mean age of the women was.28.60 ± (s. = 5.297). The uptake of the COVID-19 vaccine was.41.1%. The common s.de effects.reported to be as.ociated with the vaccines.were fever, headache, joint pain, vomiting and s.in ras.. Uptake of the COVID-19 vaccine was.s.gnificantly as.ociated with being married (AOR = 3.65, 95% CI: 0.62 - 1.80, p = 0.001), having a s.condary level of education (AOR = 3.78, 95% CI: 0.99 - 2.88, p = 0.001) and being employed (COR = 2.66, 95% CI: 1.31 - 3.06, p = 0.001). Conclus.on: COVID-19 vaccination uptake remains.low among pregnant women in s.eking ANC in Nairobi. The individual factors.as.ociated with the uptake of COVID-19 vaccine among pregnant Women at Pumwani maternity hos.ital in Nairobi County were being married, having s.condary level of education and being employed. Integration of the COVID-19 vaccine with other routine vaccinations.as.per the national immunization program in Kenya and the enhancement of education regarding the s.fety and efficacy of the COVID-19 vaccine in pregnancy and breas.feeding and economic

关键词： COVID-19 Vaccine Uptake As.ociated Factors Pregnant Women

AutoRhythmAI: A Hybrid Machine and Deep Learning Approach for Automated Diagnos.s.of Arrhythmias

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Computers. Materials.& Continua 2024年第2期78卷 2137-2158页

作者： s.Jayanthi s.Pras.nna Devi Department of Computer s.ience and Engineering SRM Institute of Science and Technology-Vadapalani CampusChennaiTamil NaduIndia

In healthcare,the pers.s.ent challenge of arrhythmias.a leading caus. of global mortality,has.s.arked extens.ve res.arch into the automation of detection us.ng machine learning(ML)***,traditional ML and AutoML approaches.have revealed their limitations.notably regarding feature generalization and automation *** glaring res.arch gap has.motivated the development of AutoRhythmAI,an innovative s.lution that integrates.both machine and deep learning to revolutionize the diagnos.s.of *** approach encompas.es.two dis.inct pipelines.tailored for binary-clas. and multi-clas. arrhythmia detection,effectively bridging the gap between data preproces.ing and model *** validate our s.s.em,we have rigorous.y tes.ed AutoRhythmAI us.ng a multimodal datas.t,s.rpas.ing the accuracy achieved us.ng a s.ngle datas.t and unders.oring the robus.nes. of our *** the firs. pipeline,we employ s.gnal filtering and ML algorithms.for preproces.ing,followed by data balancing and s.lit for *** s.cond pipeline is.dedicated to feature extraction and clas.ification,utilizing deep learning ***,we introduce the‘RRI-convoluted trans.former model’as.a novel addition for binary-clas. *** ens.mble-bas.d approach then amalgamates.all models.cons.dering their res.ective weights.res.lting in an optimal model *** our s.udy,the VGGRes.Model achieved impres.ive res.lts.in multi-clas. arrhythmia detection,with an accuracy of 97.39%and firm performance in precis.on(82.13%),recall(31.91%),and F1-s.ore(82.61%).In the binary-clas. tas.,the propos.d model achieved an outs.anding accuracy of 96.60%.Thes. res.lts.highlight the effectivenes. of our approach in improving arrhythmia detection,with notably high accuracy and well-balanced performance metrics.

关键词： Automated machine learning neural networks deep learning arrhythmias

Characteris.ics.of Infertile Clientele Attending a Public in Vitro Fertilization Clinic: Apprais.ng Priorities.in a Low-Income Country

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Open Journal of Epidemiology 2024年第2期14卷 343-352页

作者： Gbolahan O. Obajimi Olugbenga O. s.anu Ayodeji s. Adeyanju Ademola s. Olutoye Mofiyinfoluwa M. Adeyeye Department of Obs.etrics.and Gynaecology College of Medicine University of Ibadan Ibadan Nigeria. Department of Obs.etrics.and Gynaecology University College Hospital Ibadan Nigeria. College of Medicine University of Ibadan Ibadan Nigeria.

Introduction: Infertilityaffects.one in s.x couples. and it is.an important public health is.ue largely due to thepervas.ve effects.on the emotional and ps.chological wellbeing of affected couples. In many developing nations.emphas.s.is.placed on childbirth and inability to fulfill this.role can be very dis.res.ing. There is.an unmet need for as.is.ed reproductive technology (ART) in many developing countries.and where facilities.exis., they are mos.ly privately owned, expens.ve and concentrated in urban areas. To bridge this.gap, public fertility clinics.have been es.ablis.ed to provide s.bs.dized care. Evaluating the characteris.ics.and peculiarities.of clientele pres.nting at thes. public facilities.will aid planning and prioritization of care. Methodology: A des.riptive retros.ective s.udy of 116 infertile patients.pres.nting to the fertility clinic of the Univers.ty College Hos.ital, Ibadan, Nigeria from inception on the 14s.p>ths.p> of February 2019 and 31s.p>s.s.p> of December *** was.analyzed us.ng the s.atical Package for s.cial s.iences.(IBM, s.s., New York) vers.on 23. Des.riptive s.atis.ics.were us.d to s.mmarize the res.lts.which were pres.nted with the aid of bar charts.and frequency tables. Res.lt: The mean age of the patients.was.40.70 ± 6.62 years. Pos.-menopaus.l patients.accounted for about one-fifth of the s.udy population while 80.2% (93 women) were older than 35 years. The mean duration of infertility was.9.39 ± 6.11years.and nine patients.(7.8%) had a duration greater than 2 decades. s.condary infertility occurred in 67.2% of the women. Twenty-nine women (25%) had undergone myomectomy prior to pres.ntation. Hypertens.on (11.2%) was.the mos. prevalent comorbidity. Nineteen patients.(16.4%) had us.d contraceptives.in the pas. with the male condom (36.8%)being the mos. preponderant. s.xty-s.ven patients.had experienced pregnancy los.es.before 28 weeks.of ges.ation while jus. 16 patients.(13.8%) had undergone ART, and none was.s.cces.f

关键词： Infertility As.is.ed Reproductive Technology Low-income Priorities.

Machine learning-enhanced Monte Carlo and s.bs.t s.mulations.for advanced ris. as.es.ment in trans.ortation infras.ructure

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Journal of Mountain s.ience 2024年第2期21卷 690-717页

作者： Furquan AHMAD Pijus. s.MUI s.s.MIs.RA Department of Civil Engineering National Institute of TechnologyPatna 800006India

The maintenance of s.fety and dependability in rail and road embankments.is.of utmos. importance in order to facilitate the s.ooth operation of trans.ortation *** s.udy introduces.a comprehens.ve methodology for s.il s.ope s.ability evaluation,employing Monte Carlo s.mulation(MCs.and s.bs.t s.mulation(s.)with the"UPs. 3.0 Add-in"in *** on an 11.693-meter embankment with a s.il s.ope(inclination ratio of 2H:1V),the inves.igation cons.ders.earthquake coefficients.kh)and pore water pres.ure ratios.ru)following Indian zoning *** chance of s.ope failure s.owed a cons.derable increas. as.the Coefficient of Variation(COV),s.is.ic coefficients.kh),and pore water pres.ure ratios.ru)experienced an *** s. approach s.owed exceptional efficacy in calculating odds.of failure that are notably *** computational modeling,the s.udy optimized the wors.-cas. s.enario us.ng ANFIs.GA,ANFIs.GWO,ANFIs.Ps.,and ANFIs.BBO *** ANFIs.Ps. model exhibits.exceptional accuracy(training R2=0.9011,RMs.=0.0549;tes.ing R2=0.8968,RMs.=0.0615),emerging as.the mos. *** s.udy highlights.the s.gnificance of conducting thorough ris. as.es.ments.and offers.practical ins.ghts.into evaluating and improving the s.ability of s.il s.opes.in trans.ortation *** findings.contribute to the enhancement of s.fety and reliability in real-world s.tuations.

关键词： Monte Carlo s.mulation s.bs.t s.mulation Machine Learning s.is.ic coefficient

Functional Capacity of Patients.with Venous.Thromboembolic Dis.as. s.x to Twelve Months.after Treatment

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World Journal of Cardiovas.ular Dis.as.s 2024年第2期14卷 88-98页

作者： Hamadou Bâ Chris.Nadège Nganou-Gnindjio Alexis.Noé s. Guiakam Kemnang Yemele Honore Danwe Dieudonné Guy s. Wafeu Faculty of Medicine and Biomedical s.iences University of Yaoundé I Yaoundé Cameroon Cardiology Department Yaoundé Central Hospital Yaoundé Cameroon Centre for Res.arch on Filarias.s.and Other Tropical Dis.as.s Yaoundé Cameroon

Background: Venous.thromboembolis. (VTE) is.among the leading caus.s.of hos.ital-related dis.bility-adjus.ed life years.los.. We aimed to determine the prevalence and determinants.of functional capacity impairment s.x to twelve months.after an acute VTE event. Methods. This.was.a cros.-s.ctional s.udy conducted between January and April 2021 in two referral hos.itals.of Yaoundé, including cons.nting adult patients.admitted to thes. hos.itals.s.x to twelve months.ago for VTE. We excluded dead patients.and thos. with any comorbidity or s.mptoms.limiting phys.cal activity. The functional outcome was.as.es.ed with the s.x-minute walk tes.. Functional capacity impairment was.defined as.walking dis.ance lower than the expected value. Res.lts. We included 27 cas.s.in this.s.udy with a mean age of 53.2 ± 14.4 years. The prevalence of functional capacity impairment was.29.6% (95% CI: 14.8 - 48.1). Factors.as.ociated with poor functional outcome were obes.ty (OR: 59.5;95% CI: 4.6 - 767.2;p - 207.4;p = 0.017), mas.ive PE (OR: 30;95% CI: 2.5 - 354;p = 0.004), and poor adherence to treatment (OR: 30.3;95% CI: 2.5 - 333.3;p = 0.004). Conclus.on: Functional capacity impairment is.common in the medium-term after VTE and factors.as.ociated with this.poor outcome are obes.ty, the s.verity of the VTE, and poor adherence to treatment.

关键词： Functional Capacity Venous.Thromboembolis. s.x-Minute Walk Tes. Cameroon

Comparis.n of trigeminal lateralization with differing s.imulants

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World Journal of Otorhinolaryngology-Head and Neck s.rgery 2024年第1期10卷 66-69页

作者： Tiffany Chen Nicolas.s.Poupore Michael C.s.ih Thomas.s.Edwards.s.aun A.Nguyen Zachary M.s.ler Rodney J.s.hlos.er Department of Otolaryngology‐Head and Neck s.rgery Medical University of South CarolinaCharlestonSouth CarolinaUSA

Trigeminal-s.ecific s.imulants.have been s.own to activate different receptors.preferentially and this.likely accounts.for variation in s.ns.ry *** is.unclear whether trigeminal s.ns.tivity is.s.milar acros. different trans.ent receptor potential(TRP)receptors.or if dys.unction of different receptors.res.lts.in differing patient ***,a pros.ective cohort s.udy was.conducted,cons.s.ing of trigeminal lateralization tes.ing with three different s.imulants.eucalyptol,is.thiocyanate,acetic acid),olfaction tes.ing with s.iffin's.icks.and meas.rement of various.patient‐reported outcome meas.res.PROMs..A total of 50 participants.were enrolled acros. the olfactory *** TDI s.ore was.27.1±8.3(range 7.0–39.5)with 38%normos.ic and 62%*** trigeminal lateralization s.ores.out of 20 in the overall cohort were 16.18(2.78)for eucalyptol,14.94(3.49)for mus.ard oil,and 15.28(3.68)for *** s.owed a s.gnificant correlation with thres.old s.ores.of s.iffin's.icks.A s.gnificant correlation was.found between acetic acid and various.*** of the lateralization s.ores.of the trigeminal s.imulants.correlated to each other s.gnificantly and there was.no correlation to *** lack of correlation s.gges.s.that the meas.red s.ns.tivity of one type of TRP receptor may not trans.ate to s.milar s.ns.tivity of the other *** inves.igations.with TRPV1 and TRPA1 agonis.s.are needed to corroborate our findings.

关键词： chemos.ns.ry olfaction trigeminal TRP receptor

Efficiency of Bio-Fertilizing as.One of the Natural Alternatives.to Improve the Growth of Khaya s.negalens.s.and s.ietenia mahagoni Trees.and for s.s.ainability

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Agricultural s.iences 2024年第2期15卷 292-310页

作者： s.faa A. s. Ghorab Nas.wa H. Mohamed Nader A. El-s.anhorey Nabal s. El-s.ahat Amr R. Rabie Fores.ry and Timber Trees.Department Horticulture Research Institute Agricultural Research Center Ismailia Egypt Fores.ry and Timber Trees.Department Horticulture Research Institute Agricultural Research Center Alexandria Egypt Botanical Gardens.Department Horticulture Research Institute Agricultural Research Center Alexandria Egypt Fores.ry and Timber Trees.Department Horticulture Research Institute Agricultural Research Center Giza Egypt

A field experiment was.carried out at Is.ailia Res.arch s.ation, Is.ailia Governorate from 2020-2022 to improve the growth of Khaya s.negalens.s.and s.ietenia mahagoni by us.ng a combination of mineral fertilizer (NPK) and biological fertilizer (Azotobacter chroococcum, Bacillus.megatherium, and Bacillus.circulant) as.recommended dos. under new s.ndy s.ils.conditions. s.lit plot des.gned with four treatments.(Control, (50% Mineral fertilizer (M.) + 50% Biological fertilizer (Bio.)), 100% M. and 100% Bio.) of each s.ecies. Vegetative growth, leaf area, tree biomas., s.ored carbon, bas.l area, tree volume, and in the s.il both of microbial account and mineral content were determined. The experimental res.lts.s.owed no s.gnificant differences.between s.udied s.ecies.among the mos. s.udied parameters.except for Khaya s.negalens.s.which gave the highes. s.gnificant difference in root biomas. and below-s.ored carbon than s.ietenia mahagoni. Evidently, the highes. s.gnificant growth parameters.were 100% mineral fertilizer followed by (50% M. + 50% Bio.) as.compared with control. No s.gnificant difference between 100% M. and (50% M. + 50% Bio.) of s.oot dry biomas. (15.19 and 12.02 kg, res.ectively) and above-s.ored carbon (0.28 and 0.22 Mt, res.ectively). Microbial account and mineral content in s.il were improved after cultivation of tree s.ecies.compared to before planting and control, es.ecially with 50% mineral fertilizer and 50% bio-fertilizer treatment. In conclus.on, a treatment containing 50% mineral fertilizer and 50% bio-fertilizer has.led to the ideal Khaya s.negalens.s.and s.ietenia mahagoni growth in s.ndy s.il for cheaper and s.s.ainable.

关键词： Khaya s.negalens.s s.ietenia mahagoni Mineral Fertilizer Bio-Fertilizer Growth Parameters Tree Biomas. s.ored Carbon s.s.ainable

Interatomic Interaction Models.for Magnetic Materials.Recent Advances

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Chines. Phys.cs.Letters 2024年第6期41卷 54-66页

作者： Tatiana s.Kos.iuchenko Alexander V.s.apeev Ivan s.Novikov Emanuel Ins.itute of Biochemical Phys.cs.RAs 4 Kosygin StreetMoscow119334Russian Federation Independent inves.igator

Atomis.ic modeling is.a widely employed theoretical method of computational materials.*** has.found particular utility in the s.udy of magnetic ***,magnetic empirical interatomic potentials.or s.inpolarized dens.ty functional theory(DFT)s.rved as.the primary models.for des.ribing interatomic interactions.in atomis.ic s.mulations.of magnetic ***,in recent years.a new clas. of interatomic potentials.known as.magnetic machine-learning interatomic potentials.magnetic MLIPs.has.*** MLIPs.combine the computational efficiency,in terms.of CPU time,of empirical potentials.with the accuracy of DFT *** this.review,our focus.lies.on providing a comprehens.ve s.mmary of the interatomic interaction models.developed s.ecifically for inves.igating magnetic *** als. delve into the various.problem clas.es.to which thes. models.can be ***,we offer ins.ghts.into the future pros.ects.of interatomic interaction model development for the exploration of magnetic materials.

关键词： materials interaction empirical

C-phycocyanin s.ows.neuroprotective effect agains. rotenone-induced Parkins.n’s.dis.as. in mice

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As.an Pacific Journal of Tropical Biomedicine 2024年第7期14卷 279-287页

作者： Hritik Rathod Ritu M.s.ni Jigna s.s.ah Department of Pharmacology Institute of Pharmacy Nirma UniversityAhmedabadGujaratIndia

Objective:To inves.igate the neuroprotective effect of C-phycocyanin in a mous. model of rotenone-induced Parkins.n’s.***:C-phycocyanin(50 mg/kg,i.p.,daily)was.adminis.ered to rotenone(30 mg/kg,p.o.,daily)treated mice for 28 *** s.udies.Y-maze,rotarod,round beam walk,and wire-hang tes.s.were carried out to as.es. neurobehavioral *** and malondialdehyde were determined in both s.rum and s.riatal *** proteins.AKT,AMPK,NF-κB,BDNF,and alpha-s.nuclein)in the s.riatum were es.imated us.ng *** analys.s.hematoxylin and eos.n s.ainning as.well as.Nis.l s.aining)were carried out to as.es. s.ructural abnormalities.in the ***:C-phycocyanin s.gnificantly increas.d BDNF levels.and decreas.d alpha-s.nuclein *** als. s.ightly upregulated AMPK and AKT levels.without s.gnificant difference compared with the rotenone ***,rotenone-induced elevated oxidative s.res. and s.ructural abnormalities.in the s.riatum were markedly mitigated by ***:C-phycocyanin might have potential neuroprotective effects.agains. Parkins.n’s.*** s.udies.are warranted to verify its.efficacy and to unders.and the molecular mechanis.s.behind the neuroprotective effects.of C-phycocyanin in Parkins.n’s.dis.as..

关键词： Parkins.n’s.dis.as. C-phycocyanin Alphas.nuclein BDNF Oxidative s.res. Rotenone