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The History of Traditional Chinese Medicine in Britain,c.1750‑2018

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Chinese Medicine and Culture 2018年第3期1卷 108-111页

作者： Christopher ryan Pearse Cavin Department of Humanities and Social Sciences University of StrathclydeGlasgowScotlandUK

This paper discusses the genesis and transference of Traditional Chinese Medicine from China and Asia to *** looks specifically at the ways in which TCM was initially discovered and how it reach medical circles in *** also looks at the reasons why it became popular in the historical context and specifically at the presence of TCM in ***,this paper briefly traces the booms and slumps in the popularity of TCM and its place in modern medical practices in the Uk and Europe.

关键词： Acupuncture kaempfer medical discourse teale traditional chinese medicine

A rapid dehydration leaf assay reveals stomatal response differences in grapevine genotypes

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Horticulture Research 2014年第1期1卷 322-329页

作者： Daniel W Hopper ryan Ghan Grant R Cramer Department of Biochemistry and Molecular Biology University of NevadaRenoNV 89557USA.

A simple and reliable way of phenotyping plant responses to dehydration was ***-developed leaves were detached and placed in a closed plastic box containing a salt solution to control the atmospheric water potential in the *** hours of dehydration(weight loss of the leaf)was optimal for measuring changes in stomatal response to *** of the plant hormone abscisic acid(ABA)prior to leaf detachment decreased the amount of water loss,indicating that the assay was able to detect differences based on a stomatal response to *** different Vitis genotypes(***,***,*** ***,*** *** and *** *** Sauvignon)with known differences in drought tolerance were screened for their dehydration response and the results obtained corresponded to previous reports of stomatal responses in the *** differences in stomatal density along with differences in the amount and rate of water lost indicate differences in dehydration sensitivity among the genotypes *** in stomatal response to ABA were also *** had the lowest stomatal density and the highest ABA sensitivity among the genotypes screened,yet Shiraz lost the most amount of water,indicating that it was the least sensitive to *** having the highest stomatal density and intermediate stomatal sensitivity to ABA,*** lost the smallest amount of water,indicating that it was the most sensitive to *** assay presented here represents a simple and reliable phenotyping method for plant responses to leaf dehydration.

关键词： smallest stomatal drought

Synthesis of cobalt, palladium, and rhenium nanoparticles

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Tungsten 2020年第3期2卷 261-288页

作者： Shahab Ranjbar Bahadori ryan Hart Yao‑Wu Hao Department of Materials Science and Engineering University of Texas at ArlingtonArlingtonTX 76019USA

Over the past decade,metal nanoparticles(MNPs)have attracted extensive attention due to their unique physiochemical properties that make them highly applicable in various fields such as chemical sensing,energy storage,catalysis,medicine,and environmental *** physiochemical properties depend drastically on the MNP size and morphology,which are largely determined by their synthesis *** on MNPs predominantly focused on coinage metals(Au,Ag and Cu),but in the last decade research on metals with a relatively high melting temperature such as Pd,Co,and Re has seen rapid increases,mainly driven by their potential applications as *** paper presents the recent advances on different synthesis techniques of Co,Pd,and Re nanoparticles,their resulting nanostructures,as well as existing and potential applications.

关键词： Nanotechnology Co nanoparticle Pd nanoparticle Re nanoparticle Nanoparticle synthesis

Anterior segment optical coherence tomography-guided transepithelial phototherapeutic keratectomy for scarring of the central cornea following pterygium excision

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International Journal of Ophthalmology(English edition) 2020年第3期13卷 503-508页

作者： Sloan W.Rush ryan B.Rush Panhandle Eye Group AmarilloTX 79106USA Texas Tech University Health Science Center AmarilloTX 79106USA Southwest Retina Specialists AmarilloTX 79106USA

AIM:To report the outcomes of patients undergoing anterior segment optical coherence tomography-guided transepithelial phototherapeutic keratectomy(ASOCT T-PTK)for central corneal scarring after pterygium ***:The charts of 11 eyes of 10 patients that underwent ASOCT T-PTK following excision of visual axisinvolving pterygia were retrospectively reviewed from a single private practice *** visual outcomes and corneal topographic findings were evaluated 4±1 mo after pterygium excision and 6±2 mo after transepithelial phototherapeutic keratectomy(T-PTK).RESULTS:All 11 eyes tolerated both the pterygium excision and T-PTK procedure well without any significant intraoperative or postoperative *** distance visual acuity(UDVA)and manifest refraction corrected distance visual acuity(CDVA)improved after pterygium excision(P=0.03 and P=0.05,respectively).The UDVA and CDVA improved further after T-PTK(P=0.004 and P=0.002,respectively).The topographic surface asymmetry index,topographic surface regularity index,and topographic projected visual acuity significantly improved after T-PTK(P=0.0092,P=0.0022,and P=0.0002,respectively).None of the subjects lost any lines of CDVA,developed recurrence of pterygia or required keratoplasty during the postoperative ***:ASOCT T-PTK can provide excellent visual and anatomic outcomes in patients with central corneal scarring after excision of visual axis-involving pterygia.

关键词： pediatric penetrating eye injury traumatic endophthalmitis pars plana vitrectomy

Real-time temperature prediction of electric machines using machine learning with physically informed features

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Energy and AI 2023年第4期14卷 415-425页

作者： ryan Hughes Thomas Haidinger Xiaoze Pei Christopher Vagg University of Bath UK AVL List GmbH Austria

Accurate estimation of the internal temperatures of electric machines is critical to increasing their power density and reliability since key temperatures,such as magnet temperature,are often difficult to *** work presents a new machine learning based modelling approach,incorporating novel physically informed feature engineering,which achieves best-in-class accuracy and reduced training *** different features introduced are proportional to sources of machine losses and require no prior knowledge of the machine,hence the models are completely data *** using a standard experimental dataset shows that modelling errors can be reduced by up to 82.5%,resulting in the lowest mean squared error recorded in the literature of 2.40 K^(2).Additionally,models can be trained with less training data and have lower sensitivity to data ***-ically,it was possible to train a loss enhanced multilayer perceptron model to a mean squared error<5 K^(2) with 90 h of training data,and an enhanced ordinary least squares model with just 60 h to the same *** inference time of the model can be 1–2 orders of magnitude faster than competing models and requires no time to optimise hyperparameters,compared to weeks or months for other state-of-the-art prediction *** results are highly important for enabling low-cost real-time temperature monitoring of electric machines to improve operational efficiency,safety,reliability,and power density.

关键词： Thermal model Real-time Electric machine Machine learning Losses

Skeletal Blood Flow in Bone Repair and Maintenance

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Bone Research 2013年第4期1卷 311-322页

作者： ryan E.Tomlinson Matthew J.Silva Department of Orthopaedic Surgery Washington University in St.Louis Musculoskeletal Research Center Washington University in St.Louis

Bone is a highly vascularized tissue, although this aspect of bone is often overlooked. In this article, the importance of blood flow in bone repair and regeneration will be reviewed. First, the skeletal vascular anato- my, with an emphasis on long bones, the distinct mechanisms for vascularizing bone tissue, and methods for remodeling existing vasculature are discussed. Next, techniques for quantifying bone blood flow are briefly summarized. Finally, the body of experimental work that demonstrates the role of bone blood flow in fracture healing, distraction osteogenesis, osteoporosis, disuse osteopenia, and bone grafting is examined. These results illustrate that adequate bone blood flow is an important clinical consideration, particularly during bone regeneration and in at-risk patient groups.

关键词： blood flow angiogenesis vascular remodeling fracture bone repair

Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer:The role of inflammation

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World Journal of Gastroenterology 2014年第14期20卷 3751-3761页

作者： Chun Seng Lee Elizabeth J ryan Glen A Doherty Centre for Colorectal Disease St. Vincent’s University Hospital School of Medicine and Medical Sciences University College Dublin

Chemotherapy-induced diarrhea(CID)is a common and often severe side effect experienced by colorectal cancer(CRC)patients during their *** chemotherapy regimens evolve to include more efficacious agents,CID is increasingly becoming a major cause of dose limiting toxicity and merits further *** is a key factor behind gastrointestinal(GI)toxicity of *** chemotherapeutic agents activate a diverse range of pro-inflammatory pathways culminating in distinct histopathological changes in the small intestine and colonic *** we review the current understanding of the mechanisms behind GI toxicity and the mucositis associated with systemic treatment of *** into the inflammatory response activated during this process gained from various models of GI toxicity are *** inflammatory processes contributing to the GI toxicity of chemotherapeutic agents are increasingly being recognised as having an important role in the development of anti-tumor immunity,thus conferring added benefit against tumor recurrence and improving patient *** review the basic mechanisms involved in the promotion of immunogenic cell death and its relevance in the treatment of colorectal ***,the impact of CID on patient outcomes and therapeutic strategies to prevent or minimise the effect of GI toxicity and mucositis are discussed.

关键词： Chemotherapy Diarrhea Side-effects Immunogenic cell death Pro-inflammatory cytokines

A case of cerebral venous sinus thrombosis associated with Crohn’s disease:dilemma in management

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Gastroenterology Report 2016年第2期4卷 154-157,I0003页

作者： Younghoon Kwon ryan J Koene Yeilim Cho St.Joseph’s Hospital HealthEast Care SystemSaint PaulMinnesotaUSA Department of Medicine University of MinnesotaMinneapolisMinnesotaUSA

Inflammatory bowel disease(IBD)is known to increase the risk of venous *** venous sinus thrombosis(CVST)is a rare but important complication of *** diagnosis,particularly in younger patients,requires a high level of suspicion in order to prevent potentially devastating complications such as hemorrhage or venous *** paper presents a 44-year-old Caucasian woman with a previous history of Crohn’s disease and deep venous *** resonance imaging confirmed the diagnosis of *** therapeutic anticoagulation with warfarin was difficult,due to presumed pharmacological interaction between warfarin and *** should have a high index of suspicion for CVST when a patient with Crohn’s disease presents with acute headache,and be aware of challenges related to medical management.

关键词： cerebral venous sinus thrombosis Crohn’s disease anticoagulation mercaptopurine warfarin

Screening antioxidants for the protection of cochlear sensory cells

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Neural Regeneration Research 2018年第1期13卷 62-64页

作者： Dong Gu Hur Arwa Kurabi Allen F.ryan Department of Surgery/Otolaryngology School of Medicine University of CaliforniaSan Diego Department of Otorhinolaryngology Gyeongsang National University Changwon Hospital Research Service Veterans Administration Medical Center

Sensory cell damage is a major cause of hearing loss： Sensorineural hearing loss （SNHL） is a common sensory deficit characterized by tissue damage and/or cell death in the cochlea. Moderate and severe SNHL causes deficits in communication, associated with increased isolation from human relationships, and negativly impacts employabflity. Many etiologies have been associated with SNHL： Noise overexposure, certain drugs, inner or middle ear infection or immune-induced inflammation being common. However, the most prevalent form of SNHL is presbycusis or age-related hearing loss, often aggravated by other factors including a history of noise exposure, diabetes or high blood pressure （Wong and ryan, 2015）. Though systemic steroids are used in the treatment of sudden SNHL, other drugs to prevent or cure hearing loss have not yet been developed. Cochlear sensory cells, known as hair cells （HCs） and neurons have very limited repair capacity. Moreover since these cells do not regenerate, making any loss permanent, prevention of cell damage is critical to protecting hearing.

关键词： HC Screening antioxidants for the protection of cochlear sensory cells