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Hydroxytyrosol and Parkinson's disease:protective actions against alpha-synuclein toxicity

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Neural Regeneration Research 2024年第7期19卷 1427-1428页

作者： ruth Hornedo-Ortega Ana M.Espinosa-Oliva Departamento de Nutrición y Bromatología Toxicología y Medicina LegalFacultad de FarmaciaUniversidad de SevillaSevilleSpain Instituto de Biomedicina de Sevilla IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSevillaSpain Departamento de Bioquímica y Biología Molecular Facultad de FarmaciaUniversidad de SevillaSevillaSpain

Parkinson’s disease:Parkinson’s disease(PD) is the second most prevalent neurodegenerative disease,after Alzheimer’s disease,affecting 1%of the general population over the age of *** to data from the World Health Organization(WHO),its prevalence has doubled in the past 25 *** 2019,global estimates indicated over 8.5 million individuals with PD and it is suggested that PD caused 329000 deaths,an increase of over 100% since 2000(WHO,2022).

关键词： protective Alzheimer prevalence

Consequences of early life stress on the structure and function of the adult mouse retina

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Neural Regeneration Research 2024年第1期19卷 150-151页

作者： Juan S.Calanni ruth E.Rosenstein Laboratory of Retinal Neurochemistry and Experimental Ophthalmology Department of Human BiochemistrySchool of Medicine/CEFyBOUniversity of Buenos Aires/CONICETBuenos AiresArgentina

Early-life stress(ELS)refers to a period of environmental/social deprivation,physica l,sexual or emotional abuse,neglect,severe and/or chronic trauma in the prenatal/early postnatal stage,which is closely related to many adverse psychiatric disorders later in life,such as depressive disorder,substance abuse,dysthymia,panic,anxiety,and suicidal behavior in adulthood(Waters and Gould,2022).

关键词： stress life Gould

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BACK TO SCHOOL

空中英语教室（初级版．大家说英语） 2024年第9期 9-12,50,51,56页

作者： ruth Devlin 不详

Many students feel excited about going back to *** want to meet new teachers,new classmates and learn new *** somestudents *** school starts,they can't sleep in or text their friends all the *** also worry about homew... 详细信息

关键词： excited worry friends

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ONE GRAIN OF RICE

空中英语教室（初级版．大家说英语） 2024年第9期 20-23,52,56页

作者： ruth Devlin 不详

ong ago,a raja lived in *** people were rice *** raja said to them,"Give me most of your rice,and I will store *** the time of famine comes,everyone will have rice to eat."So each year,the raja took most of the people... 详细信息

关键词： everyone store stored

Improving Supply Chain Strategies towards Mitigating the Effect of Crude Oil Theft and Pipeline Vandalism in the Nigerian Oil and Gas Industry: A Case Study of the Nigerian National Petroleum Corporation (NNPC)

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Open Journal of Yangtze Oil and Gas 2024年第3期9卷 75-93页

作者： ruth Agwom Panle Department of Business Administration Faculty of Management Sciences University of Jos Jos Nigeria.

Generically, SCM may be said to include all activities carried out to ensure proper functioning of the supply chain. The activities included in proper management of a supply chain broadly include logistics activities, planning and control of the flow of information and materials in a firm, management of relationships with other organizations and government intervention, However, crude oil theft and pipeline vandalism are established products supply chain disruptors in Nigeria which are rendering the task of running an efficient petroleum supply chain onerous. This paper aims to establish the importance of effective supply chain strategies for companies in the oil and gas industry with special focus on the Nigerian oil and gas sector and the strategies by which the state oil and gas corporation in this sector may mitigate disruptions to its supply chain. This study investigates the enhancement of supply chain strategies towards meeting the challenge of crude oil theft and pipeline vandalism, using the Nigerian National Corporation (NNPC) as a case study. Based on this study, data were collected from two sources: A summary of incident reports obtained from NNPC and an interview with personnel in the PPMC Department. Incident report refers to a report produced when accidents such as equipment failure, injury, loss of life, or fire occur at the work site. Content analysis is utilized to evaluate data obtained from interview responses, CBN financial stability reports, NDIC annual reports, circulars, banking supervision reports and implementation guidelines. The study found out that NNPC should endeavor to sustain its value chain and ward of pipeline vandals and crude oil thieves by engaging in community partnership, detailing security outfits to ensure its pipelines’ right of way and bridging. Concluded that the oil supply chain of the Nigerian National Petroleum Corporation has been plagued by disruptions in the form of crude oil theft and pipeline vandalism which has h

关键词： Supply Chain Strategies Management Production Crude Oil Theft Pipeline Vandalism Information Technology Operations

One-pot and One-step Cu(0)-mediated Reversible-Deactivation Radical Polymerization of N-Isopropylacrylamide(NIPAM) in Water

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Chinese Journal of Polymer Science 2024年第1期42卷 1-6,I0004页

作者： Zi-Shan Li Jing Lyu Bei Qiu Ying-Hao Li ruth Foley Ri-Jian Song Melissa Johnson Qiang Geng Wen-Xin Wang Institute of Precision Medicine(AUST-IPM) Anhui University of Science and TechnologyHuainan 232001China Charles Institute of Dermatology School of MedicineUniversity College DublinDublin D04 V1W8Ireland

Copper(0)-mediated reversible-deactivation radical polymerization(Cu(0)-mediated RDRP) of the water-soluble monomer Nisopropylacrylamide(NIPAM) has been challenging with the problems of high dispersity, poor control over the molecular weights(MWs) or complex or multi reaction steps, etc. In this work, we report the well-controlled polymerization of NIPAM in water via a facile one-pot and one-step Cu(0)-mediated RDRP. The results of this approach show that the key for kicking off the Cu(0)-mediated NIPAM RDRPs is to ensure sufficient Cu~I at the very beginning, and the key to achieve a well-controlled chain growth is to provide adequate deactivation strength during the polymerization process. For NIPAM, which has a high propagation rate constant, the deactivation control can be effectively enhanced by extra adding deactivator(i.e., Cu~II) to the system. Moreover, a low reaction temperature(4 ℃) is necessary in the controlled synthesis of higher MW poly(Nisopropylacrylamide)(PNIPAM) to avoid the compromise in control caused by the phase transition from its lower critical solution temperature(LCST). Through this new kinetically controlled strategy, PNIPAMs with well-defined structure, narrow molecular weight distributions(MWDs) and varied MWs were successfully achieved.

关键词： Cu(0)-mediated RDRP N-isopropylacrylamide Propagation Deactivation Reaction parameters

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Hang in There!

空中英语教室（初级版．大家说英语） 2024年第9期 24-25,53页

作者： ruth Devlin 不详

There are many good phrases that use the word *** you hang up on someone,you end a phone call *** do not finish the *** you hang out with people,you spend time with *** you want to hang on to something,you want to save *** don't want to let it *** you hang it up,you quit something orlet it *** when you tell someone,"Hang in there!"you're encouraging them to keep doing something.

关键词： something someone suddenly

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JEJU ISLAND

空中英语教室（初级版．大家说英语） 2024年第9期 13-15,51页

作者： ruth Devlin 不详

South Korea's Jeju Island has a lot of natural *** of people visit the island each *** Mount Hallasan is a popular *** 1,950 meters,it's the highest mountain in South *** is possible to hike all the way to the top and... 详细信息

关键词： island Island Mount

A Uniform or Regular Clothes?

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空中英语教室（初级版．大家说英语） 2024年第9期 41-42,55,56页

作者： ruth Devlin 不详

What should students wearto school?Some say *** ca reduce bullying becauseeeveryone wears the same *** can't tease others about their ***,students focus better in class when they wear *** aren't thinking about *** rea... 详细信息

关键词： everyone wear Uniform