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基于随机森林的川东北城市群臭氧污染预报研究

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中国测试 2024年第11期50卷 150-159页

作者：宋龙娟胡睿琪刘兵王安怡邓小函马骏康平陈柯弟黄玉林孙谦王长发四川师范大学化学与材料科学学院四川成都610066 四川省达州生态环境监测中心站四川达州635099 成都信息工程大学大气科学学院高原大气与环境四川省重点实验室四川成都610225 西南土地资源评价与监测教育部重点实验室(四川师范大学) 四川成都610068 四川省泸州生态环境监测中心站四川泸州646099 四川省广元生态环境监测中心站四川广元628040

为探究川东北城市群气象因子间的非线性交互作用对近地层臭氧(O_(3))污染的影响,并开展未来1~10天的O_(3)浓度预报,本研究基于2017-2021年川东北城市群O_(3)浓度监测数据、气象数据与欧洲中心细网格模式预报资料,分析近5年川东北O_(3)... 详细信息

为探究川东北城市群气象因子间的非线性交互作用对近地层臭氧(O_(3))污染的影响,并开展未来1~10天的O_(3)浓度预报,本研究基于2017-2021年川东北城市群O_(3)浓度监测数据、气象数据与欧洲中心细网格模式预报资料,分析近5年川东北O_(3)污染时空特征,并以此为基础选取预报因子,经随机森林(RF)模型筛选关键特征因子作为模型输入数据,构建本地化动态时效RF臭氧预报模型。结果表明:1)2017-2021年川东北O_(3)浓度年评价值呈现“M”型的变化趋势;各月O_(3)超标天数与O_(3)浓度月评价值变化均呈现“双峰型”趋势;O_(3)浓度日变化则呈现“单峰型”趋势。2)特征选择结果显示川东北城市群影响O_(3)浓度变化的关键特征因子以气温、云量、起报天O_(3)浓度、海平面气压等变量为主。3)以川东北城市群整体来看,RF臭氧预报模型误差项处于合理范围内,预报性能良好,对川东北城市群O_(3)浓度有较高的解释性。

关键词：随机森林模型臭氧污染川东北城市群浓度预报

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Engineering a flexible and mechanically strong composite electrolyte for solid-state lithium batteries

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Journal of Energy Chemistry 2020年第7期29卷 187-190,I0006页

作者： Tengrui Wang ruiqi Zhang Yongmin Wu Guannan Zhu Chenchen hu Jiayun Wen Wei Luo Institute of New Energy for Vehicles School of Materials Science and EngineeringTongji UniversityShanghai 201804China SAIC Motor Corporation Ltd Shanghai 201804China State Key Laboratory of Space Power-Sources Technology Shanghai Institute of Space Power-SourcesShanghai 200245China

Lithium-ion batteries(LIBs)have greatly facilitated our daily lives since 1990s[1,2].To meet the ever-increasing demand on energy density,Li metal is seen as the ultimate anode because of its ultra-high specific capacity(3860 m Ah/g)and the lowest electrochemical potential(-3.04 V *** standard hydrogen electrode)[3–6].However,issues of Li metal anode,such as Li dendrite formation and large volume change during plating/stripping。

关键词： Solid-state batteries Solid polymer electrolytes Blending Li6.5La3Zr1.5Ta0.5O12 Mechanical strength

尼帕病毒的环境存活能力及相关消毒剂研究现状

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中国动物检疫 2024年第11期41卷 100-105页

作者：胡瑞琪崔超杰李云涛戈胜强马喆张慧魏荣王志亮南京农业大学江苏南京210095 中国动物卫生与流行病学中心山东青岛266032 山东农业大学山东泰安271018 云南农业大学动物医学院云南昆明650201 青岛市现代生物工程及动物疫病研究重点实验室山东青岛266032 农业农村部动物生物安全风险预警及防控重点实验室(南方) 山东青岛266032

尼帕病毒(NiV)是一种高致病性病毒,其在环境中的存活能力及对消毒剂的敏感性对防控其人兽感染至关重要。NiV对温度、干燥、紫外线均较敏感,对pH的耐受范围较广;在适宜环境下,病毒在尿液和果汁中稳定性较高。季铵类、含氯类及高浓度醇类... 详细信息

尼帕病毒(NiV)是一种高致病性病毒,其在环境中的存活能力及对消毒剂的敏感性对防控其人兽感染至关重要。NiV对温度、干燥、紫外线均较敏感,对pH的耐受范围较广;在适宜环境下,病毒在尿液和果汁中稳定性较高。季铵类、含氯类及高浓度醇类消毒剂等均可完全灭活NiV,但其有效浓度和消毒时间是确保病毒被完全灭活的关键因素,同时要现配现用。本文综述了NiV在不同环境因素下的存活能力及其相关消毒剂研究现状,以期为NiV感染防控提供参考。

关键词：尼帕病毒传播途径环境存活能力消毒剂

武汉亮斑扁角水虻幼虫肠道微生物对其成虫产卵行为的影响

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生物资源 2017年第4期39卷 283-292页

作者：胡芮绮马世腾李天琪郑龙玉蔡珉敏喻子牛张吉斌华中农业大学生命科学技术学院微生物农药国家工程研究中心农业微生物学国家重点实验室湖北武汉430070

研究武汉亮斑扁角水虻幼虫肠道微生物对武汉亮斑水虻成虫产卵行为的影响。首先使用LB(Luria-Bertani)培养基对武汉亮斑水虻幼虫肠道微生物进行分离纯培养,筛选得到23株肠道微生物。以灭菌的LB液体培养基为阴性对照,使用已证实引诱产卵... 详细信息

研究武汉亮斑扁角水虻幼虫肠道微生物对武汉亮斑水虻成虫产卵行为的影响。首先使用LB(Luria-Bertani)培养基对武汉亮斑水虻幼虫肠道微生物进行分离纯培养,筛选得到23株肠道微生物。以灭菌的LB液体培养基为阴性对照,使用已证实引诱产卵效果好的来自武汉亮斑水虻卵表的属于戈登氏菌属的细菌(Gordonia sihwensis)FE06为阳性对照,利用筛选到的武汉亮斑水虻幼虫肠道微生物摇瓶发酵液对武汉亮斑水虻成虫进行产卵行为实验。发现有5株武汉亮斑水虻幼虫肠道微生物(BSFLG01、BSFLG03、BSFLG04、BSFLG05、BSFLG06)对武汉亮斑水虻产卵有显著的积极促进作用,其中3株(BSFLG03、BSFLG05、BSFLG06)对水虻成虫产卵的引诱作用明显强于所设立的阳性对照FE06;菌株BSFLG07为一种毕赤酵母菌(Pichia kudriavzevii),对武汉亮斑水虻产卵有消极影响。经菌落培养特征、菌体形态比较、16SrDNA或18SrDNA序列测定和发育树比对分析,鉴定出这5种具有显著引诱武汉亮斑水虻产卵作用的微生物分别为:枯草芽胞杆菌(Bacillus subtilis)BSFLG01、一种沙雷氏菌(Serratiasp.)BSFLG03、库德毕赤酵母(Pichia kudriavzevii)BSFLG04、皱落假丝酵母(Candida rugosas)BSFLG05、粘质沙雷氏菌(Serratia marcescens)BSFLG06。

关键词：武汉亮斑水虻幼虫肠道微生物产卵行为

Bioinspired Hemostatic Strategy via Pulse Ejections for Severe Bleeding Wounds

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Research 2024年第1期2023卷 281-299页

作者： Bitao Lu Enling hu Weiwei Ding Wenyi Wang ruiqi Xie Kun Yu Fei Lu Guangqian Lan Fangyin Dai State Key Laboratory of Silkworm Genome Biology College of SericultureTextile and Biomass SciencesSouthwest UniversityChongqing 400715China Chongqing Engineering Research Center of Biomaterial Fiber and Modern Textile Chongqing 400715China Division of Trauma and Surgical Intensive Care Unit Research Institute of General SurgeryJinling HospitalMedical School of Nanjing UniversityNanjing210002 Jiangsu ProvinceChina Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHong KongChina

Efficient hemostasis during emergency trauma with massive bleeding remains a critical challenge in prehospital ***,multiple hemostatic strategies are critical for treating large bleeding *** this study,inspired by bombardier beetles to eject toxic spray for defense,a shape-memory aerogel with an aligned microchannel structure was proposed,employing thrombin-carrying microparticles loaded as a built-in engine to generate pulse ejections for enhanced drug *** aerogels,after contact with blood,can rapidly expand inside the wound,offering robust physical barrier blocking,sealing the bleeding wound,and generating a spontaneous local chemical reaction causing an explosivelike generation of CO_(2) microbubbles,which provide propulsion thrust to accelerate burst ejection from arrays of microchannels for deeper and faster drug *** ejection behavior,drug release kinetics,and permeation capacity were evaluated using a theoretical model and experimentally *** novel aerogel showed remarkable hemostatic performance in severely bleeding wounds in a swine model and demonstrated good degradability and biocompatibility,displaying great potential for clinical application in humans.

关键词： wound sealing offering

Unveiling the time-temperature dependence of metastability of supercooled liquid using nano-calorimetry

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Science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 119-127页

作者： Yijun Ding Lijian Song Zheng Wang ruiqi Yu Junqiang Wang Lina hu Yuanzheng Yue Edgar D.Zanotto Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong University Jinan 250061China Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201China Key Laboratory of Experimental Teratology Shandong University Jinan 250061 China Department of Chemistry and Bioscience Aalborg UniversityAalborg 9220Denmark Department of Materials Engineering Federal University of Sao CarlosSao Carlos SP 13.565-905Brazil

There is a lack of understanding of both the conversion of an unstable glass into a metastable supercooled liquid(MSL) upon heating and the metastability of MSLs. In this study, we investigated the time-and temperature-dependent metastability of an MSL using an advanced nano-calorimetric technique. The chosen Au-based metallic glass(Au MG) allowed adequate probing of its MSL in a temperature range between 10 and 70 K above the standard glass transition temperature. We found that the survival time of the MSL state is a quadratic function of temperature. Beyond this duration threshold, the sample undergoes fast crystallization even if it is below the crystallization temperature that is measured using differential scanning *** transmission electron microscopy, we observed the formation of clusters with a partially ordered lattice structure during relaxation in the Au MG sample fabricated using a nano-calorimeter. The atomic ordering within the clusters was enhanced by increasing time and temperature in the MSL region. Once the as-produced glass entered the MSL stage upon heating followed by a quenching stage at a given rate, the mechanical properties of the quenched glass remained the same regardless of its holding temperature and duration within the MSL region. This work provides insights into the glass-MSL-crystal transformation and offers guidance for designing standard metallic glasses for property characterizations.

关键词： metallic glass supercooled liquid relaxation nucleation nano calorimetric technology

pH-Responsive Theranostic Colloidosome Drug Carriers Enable Real-Time Imaging of Targeted Thrombolytic Process with Near-Infrared-II for Deep Venous Thrombosis

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Research 2024年第3期2024卷 17-33页

作者： Yaxin Ye Zhechang Chen Shengzhang Zhang Paul Slezak Fei Lu ruiqi Xie Dongwon Lee Guangqian Lan Enling hu State Key Laboratory of Resource Insects College of SericultureTextile and Biomass SciencesSouthwest UniversityChongqing 400715China Department of Cardiovascular Medicine Yueqing People's Hospital.Wenzhou 325699China Ludwig Boltzmann Institute for Traumatology AUVA Research Center1200 ViennaAustria Department of Bionanotechnology and Bioconvergence Engineering and Department of Polymer-Nano Science and Technology Jeonbuk National UniversityJeonjuChonbuk 54896Republic of Korea School of Fashion and Textiles The Hong Kong Polytechnic UniversityHong KongChina

Thrombosis can cause life-threatening disorders. Unfortunately, current therapeutic methods for thrombosis using injecting thrombolytic medicines systemically resulted in unexpected bleeding complications. Moreover, the absence of practical imaging tools for thrombi raised dangers of undertreatment and overtreatment. This study develops a theranostic drug carrier, Pkr(IR-Ca/Pda-uPA)-cRGD, that enables real-time monitoring of the targeted thrombolytic process of deep vein thrombosis (DVT). Pkr(IR-Ca/Pda-uPA)-cRGD, which is prepared from a Pickering-emulsion-like system, encapsulates both near-infrared-II (NIR-II) contrast agent (IR-1048 dye, loading capacity: 28%) and urokinase plasminogen activators (uPAs, encapsulation efficiency: 89%), pioneering the loading of multiple drugs with contrasting hydrophilicity into one single-drug carrier. Upon intravenous injection, Pkr(IR-Ca/Pda-uPA)-cRGD considerably targets to thrombi selectively (targeting rate: 91%) and disintegrates in response to acidic thrombi to release IR-1048 dye and uPA for imaging and thrombolysis, respectively. Investigations indicate that Pkr(IR-Ca/Pda-uPA)-cRGD enabled real-time visualization of targeted thrombolysis using NIR-II imaging in DVT models, in which thrombi were eliminated (120 min after drug injection) without bleeding complications. This may be the first study using convenient NIR-II imaging for real-time visualization of targeted thrombolysis. It represents the precision medicine that enables rapid response to acquire instantaneous medical images and make necessary real-time adjustments to diagnostic and therapeutic protocols during treatment.

关键词： Infrared enable eliminated

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铜对动物脂质代谢影响的研究进展

中国饲料 2024年第13期 94-100页

作者：刁慧汤文杰周梦佳晏家友魏小兰黄崇波严鸿林何鹏王天蔚胡睿琪付洪森李书伟四川省畜牧科学研究院动物遗传育种四川省重点实验室四川成都610066 四川省畜科集团有限公司畜禽生物制品四川省重点实验室四川成都610066 四川畜科生物发展有限公司四川成都611330 西南科技大学生命科学与工程学院四川绵阳621010

铜是动物机体必需的营养元素,其以辅基的形式参与体内多种酶(细胞色素氧化酶、铜蓝蛋白、过氧化物歧化酶、赖氨酰氧化酶等)的构成,从而参与生物体的多种代谢过程,影响动物生长发育、造血、免疫等功能。研究表明,添加高铜有助于改善动物... 详细信息

铜是动物机体必需的营养元素,其以辅基的形式参与体内多种酶(细胞色素氧化酶、铜蓝蛋白、过氧化物歧化酶、赖氨酰氧化酶等)的构成,从而参与生物体的多种代谢过程,影响动物生长发育、造血、免疫等功能。研究表明,添加高铜有助于改善动物生产性能,但会导致体内铜过量蓄积,改变机体代谢,影响体脂合成,与多种疾病的发生发展有关;铜缺乏与人的高胆固醇血症、心血管疾病、非酒精性脂肪肝等多种疾病有密切关系。因此,本文系统地综述了铜在动物体内的代谢,阐明铜对脂质代谢调控和畜禽产品品质的影响,为铜在动物生产中的科学应用提供参考,同时指出铜在未来需要进一步探讨和研究的方向。

关键词：铜吸收转运脂质代谢畜产品品质动物

Dual-Driven Hemostats Featured with Puncturing Erythrocytes for Severe Bleeding in Complex Wounds

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Research 2022年第4期2022卷 119-135页

作者： Haoyu Qiu Guangqian Lan Weiwei Ding Xinyu Wang Wenyi Wang Dahua Shou Fei Lu Enling hu Kun Yu Songmin Shang ruiqi Xie State Key Laboratory of ilkworm Genome Biology College of SericultureTextile and Biomass SciencesSouthwest UniversityChongqing 400715China Chongqing Engineering Research Center of Biomaterial Fiber and Modern Textile Chongqing 400715China Division of Trauma and Surgical Intensive Care Unit Research Institute of General SurgeryJinling HospitalMedical School of Nanjing UniversityNanjing210002 Jiangsu ProvinceChina Institute of Textiles and Clothing The Hong Kong Polytechnic UniversityKowloonHong Kong

Achieving rapid hemostasis in complex and deep wounds with secluded hemorrhagic sites is still a challenge because of the difficulty in delivering hemostats to these *** this study,a Janus particle,SEC-Fe@CaT with dual-driven forces,bubble-driving,and magnetic field–(MF–)mediated driving,was prepared via in situ loading of Fe_(3)O_(4) on a sunflower sporopollenin exine capsule(SEC),and followed by growth of flower-shaped CaCO3 *** bubble-driving forces enabled SEC-Fe@CaT to self-diffuse in the blood to eliminate agglomeration,and the MF-mediated driving force facilitated the SEC-Fe@CaT countercurrent against blood to access deep bleeding sites in the *** the movement in blood flow,the meteor hammer-like SEC from SEC-Fe@CaT can puncture red blood cells(RBCs)to release procoagulants,thus promoting activation of platelet and rapid *** tests suggested that SEC-Fe@CaT stopped bleeding in as short as 30 and 45 s in femoral artery and liver hemorrhage models,*** contrast,the similar commercial product Celox™required approximately 70 s to stop the bleeding in both bleeding *** study demonstrates a new hemostat platform for rapid hemostasis in deep and complex *** was the first attempt integrating geometric structure of sunflower pollen with dual-driven movement in hemostasis.

关键词： driving bubble eliminate