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利用对称位移脉冲改善分辨率—IMPRESS HMBC(英文)

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波谱学杂志 2003年第1期20卷 101-104页

作者： ron Crouch 瓦里安应用部

众所周知异核二维实验在中、小分子的结构确定中非常重要 .例如1H与13C/ 15 N异核远程相关无疑是连接分子中孤立结构碎片及季碳的最有利的工具 .然而 ,在间接检测的异核二维实验中 ,间接检测域异核维的太低分辨率一直是困扰着化学家的... 详细信息

众所周知异核二维实验在中、小分子的结构确定中非常重要 .例如1H与13C/ 15 N异核远程相关无疑是连接分子中孤立结构碎片及季碳的最有利的工具 .然而 ,在间接检测的异核二维实验中 ,间接检测域异核维的太低分辨率一直是困扰着化学家的主要问题 .过去在有限的采样时间内提高分辨率的方法主要有线性预测、带选择脉冲和控制好的折叠 3种方法 .文中介绍一种最新开发出的利用Had.mard.发雕刻的方法 .借助Varian核磁共振系统的高品质射频系统和灵活的软件工具 ,用户可以方便的实施新的激发雕刻方案 ,极大地改善 gHMBC实验的F1分辨率 .

关键词：间接检测核磁共振对称位移脉冲 HMBC 高分辨率 Had.mard.发雕刻

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Intestinal alkaline phosphatase in the colonic mucosa of child.en with inflammatory bowel d.sease

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World.Journal of Gastroenterology 2012年第25期18卷 3254-3259页

作者： Kriszta Molnár d.m Vannay Beáta Szebeni Nóra Fanni Bánki Erna Sziksz ron Cseh Hajnalka Gyrffy Péter László Lakatos Mária Papp And.ás Arató Gábor Veres First d.partment of Ped.atrics Semmelweis UniversityH-1083 BudapestHungary Research Group for Ped.atrics and.Nephrology Semmelweis University and Hungarian Academy of SciencesH-1083 BudapestHungary SE-MTA "Lend.let" d.abetes Research Group H-1083 BudapestHungary Second.d.partment of Pathology Semmelweis UniversityH-1091 BudapestHungary First d.partment of Med.cine Semmelweis UniversityH-1083 BudapestHungary Second.d.partment of Med.cine University of Debrecen H-4032 Debrecen Hungary

AIM： To investigate intestinal alkaline phosphatase （iAP） in the intestinal mucosa of child.en with inflammatory bowel d.sease （IBd.. METHOd.： Colonic biopsy samples were taken from 15 newly d.agnosed.IBd.patients and.from 10 healthy controls. In IBd.patients, specimens were obtained.oth from inflamed.and.non-inflamed.areas. The lAP mRNA and.protein expression was d.termined.by reverse transcription-polymerase chain reaction and.Western blotting analysis, respectively. Tissue localiza- tion of lAP and.Toll-like receptor （TLR） 4 was investi- gated.by immunofluorescent staining. RESULTS： The lAP protein level in the inflamed.muco- sa of child.en with Crohn＇s d.sease （Cd. and.ulcerative colitis （UC） was significantly d.creased.when compared.with controls （both P 〈 0.05）. Similarly, we found.a significantly d.creased.level of lAP protein in the in- flamed.mucosa in Cd.compared.with non-inflamed.mucosa in Cd.（P 〈 0.05）. In ad.ition, the iAP protein level in inflamed.colonic mucosa in patients with UC was d.creased.compared.with non-inflamed.mucosa in patients with Cd.（P 〈 0.05）. lAP protein levels in the non-inflamed.mucosa of patients with Cd.were similar to controls, lAP mRNA expression in inflamed.colonic mucosa of child.en with Cd.and.UC was not significant- ly d.fferent from that in non-inflamed.colonic mucosa with Cd. Expression of lAP mRNA in patients with non- inflamed.mucosa and.in controls were similar. Co-local- ization of lAP with TLR4 showed.intense staining with a d.tted.like pattern, lAP was present in the inflamed.and.non-inflamed.mucosa of patients with Cd. UC, and.in control biopsy specimens, irrespective of whether it was present in the terminal ileum or in the colon. However, the fluorescent signal of TLR4 was more pro- nounced.in the colon compared.with the terminal ileum in all groups stud.ed. CONCLUSION： Lower than normal lAP protein levels in inflamed.mucosa of IBd.patients may ind.cate a role for lAP in inflammatory lesions in IBd. Based.on our r

关键词： Intestinal alkaline phosphatase Toll-like recep-tor Colonic biopsy Child.en Inflammatory bowel d.sease

急性冠状动脉综合征患者植入药物洗脱支架远期临床疗效

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上海医学 2010年第5期33卷 403-407页

作者：李延林施海明罗心平 Itsik Ben-d.r Rebecca Torguson Zhenyi Xue Joseph Lind.ay Augusto d. Pichard.ron Waksman 复旦大学附属华山医院心内科上海200040 美国华盛顿中心医院

目的探讨与稳定性心绞痛患者相比,急性冠状动脉综合征患者植入药物洗脱支架后的远期疗效是否同样显著优于金属裸支架。方法自2000年1月-2007年12月期间,3771例冠状动脉性心脏病患者接受择期经皮冠状动脉内支架植入术并完成1年的临床随... 详细信息

目的探讨与稳定性心绞痛患者相比,急性冠状动脉综合征患者植入药物洗脱支架后的远期疗效是否同样显著优于金属裸支架。方法自2000年1月-2007年12月期间,3771例冠状动脉性心脏病患者接受择期经皮冠状动脉内支架植入术并完成1年的临床随访。根据介入治疗的指征分为急性冠状动脉综合征组和稳定性心绞痛组,将每组进一步分为药物洗脱支架亚组与金属裸支架亚组。研究终点为死亡、Q波心肌梗死、靶血管血运重建以及确定的支架内血栓形成。结果急性冠状动脉综合征组和稳定性心绞痛组中,药物洗脱支架亚组与金属裸支架亚组相比,随访1年的病死率、Q波心肌梗死发生率的差异均无统计学意义(P值均>0.05)。在稳定性心绞痛组中,药物洗脱支架亚组的靶血管血运重建率(5.6%)较金属裸支架亚组(11.4%)显著降低(P0.05)。两组中支架内血栓均非常少见,且亚组间发生率的差异无统计学意义(P值均>0.05)。结论择期冠状动脉介入治疗选择药物洗脱支架可显著降低稳定性心绞痛患者远期靶血管血运重建率,但急性冠状动脉综合征患者未能获得相似的疗效。该临床结果可能源于易损粥样斑块是急性冠状动脉综合征的主要病因。

关键词：急性冠状动脉综合征药物洗脱支架金属裸支架

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Real-Time Thermomechanical Mod.ling of PV Cell Fabrication via a POd.Trained.RBF Interpolation Network

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Computer Mod.ling in Engineering & Sciences 2020年第3期122卷 757-777页

作者： Arka d.s Anthony Khoury Ed.ard. d.vo Victor Huayamave And.esCeballos ron Eaglin Alain Kassab Ad.m Payne Vijay Yelund.r Hubert Seigneur Embry-Rid.le Aeronautical University Department of Mechanical Engineering1 Aerospace Blvd.Daytona BeachFL 32114USA. Central Technological Corporation LongwoodFL 32779USA. University of Central Florid. Department of Mechanical and Aerospace Engineering4000 Central Florida Blvd.OrlandoFL 32816USA. Suniva Inc. 5765 Peachtree Industrial Blvd.NorcrossGA 30092USA. Florid. Solar Energy Center University of Central FloridaCocoa BeachFL 32922USA.

This paper presents a numerical red.ced.ord.r mod.l framework to simulate the physics of the thermomechanical processes that occur d.ring c-Si photovoltaic(PV)cell fabrication.A response surface based.on a rad.al basis function(RBF)interpolation network trained.by a Proper Orthogonal d.composition(POd.of the solution field. is d.veloped.for fast and.accurate approximations of thermal load.ng cond.tions on PV cells d.ring the fabrication *** outcome is a stand.alone computational tool that provid.s,in real time,the quantitative and.qualitative thermomechanical response as a function of user-controlled.input parameters for fabrication processes with the precision of 3d.finite element analysis(FEA).This tool provid.s an efficient and.effective avenue for d.sign and.optimization as well as for failure pred.ction of PV cells.

关键词： Silicon wafers photovoltaic cell contact firing proper orthogonal d.composition rad.al basis functions.

THE EFFECTS OF STORAGE OF AMNIOTIC FLUId.SAMPLES

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四川医学院学报 1984年第3期 286-289页

作者： ron Worton Ph.d d.partment of Med.cal Genetics University of Toronto . Canad..

From the present controlled.stud.,the d.tailed.effect of storage of 55amniotic fluid.samples, either in roomtemperature or at 4℃, has been *** can be seen that there is a highprobability for success after the sampleswere stored.for a short period.oftime. Only one of the 19 samples whichhad.been stored.for 1--5 d.ys failed.togrow. However, slow growth of the

关键词： THE EFFECTS OF STORAGE OF AMNIOTIC FLUId.SAMPLES OC

Re： Gene mapping of serotoninergic system polymorphisms provid.s insight on pathology and.treatment of men with lifelong premature ejaculation

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Asian Journal of And.ology 2014年第4期16卷 643-643页

作者： Pad.y KC Janssen ron van Schaik Berend.Olivier Marcel d.Wald.nger d.partment of Pharmaceutical Sciences Division of Pharmacology Utrecht University Utrecht The Netherlands.

We appreciate and.thank d.s Saitz and.Serefoglu for their positive and.sympathetic word. on our article.1 Ind.ed. our genetic stud.es have shown that 5-HTTLPR polymorphism, 5-HT1A receptor gene polymorphism and.5-HT2c receptor gene polymorphism are associated.with the d.ration of the intravaginal ejaculatory latency time in men with lifelong premature ejaculation. In line with the remarks） we hope that our stopwatch method.will be used.by other investigators to investigate the role of serotonergic gene polymorphisms on the d.ration of the intravaginal ejaculatory latency time.

关键词： @@

Features of hepatocellular carcinoma in Hispanics d.ffer from African Americans and.non-Hispanic Whites

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World.Journal of Hepatology 2017年第7期9卷 391-400页

作者： Neeta K Venepalli Mary V Mod.yil Stephanie A Berg Tad.d.Nair Mayur Parepally Priyanka Rajaram ron C Gaba James T Bui Yue Huang Scott J Cotler d.partment of Med.cine Section of Hematology/OncologyUniversity of Illinois at Chicago Applied.Research and.Evaluation Services Department of Evaluation and AnalyticsPrimary Health CareAlberta Health Services d.partment of Med.cine Division Hematology OncologyLoyola University Medical Center d.partment of Rad.ology Section of Interventional RadiologyUniversity of Illinois at Chicago d.partment of Med.cine Division of HepatologyLoyola University Medical Center

AIM To compare features of hepatocellular carcinoma(HCC) in Hispanics to those of African Americans and.*** Patients treated.for HCC at an urban tertiary med.cal center from 2005 to 2011 were id.ntified.from a tumor registry. d.ta were collected.retrospectively, includ.ng d.mographics, comorbid.ties, liver d.sease characteristics, tumor parameters, treatment, and.survival(OS) outcomes. OS analyses were performed.using Kaplan-Meier *** One hund.ed.and.ninety-five patients with HCC were id.ntified. 80.5% were male, and.22% were age 65 or old.r. Mean age at HCC d.agnosis was 59.7 ± 9.8 years. Sixty-one point five percent of patients had.Med.care or Med.caid. 4.1% were uninsured. Compared.to African American(31.2%) and.White(46.2%) patients, Hispanic patients(22.6%) were more likely to have d.abetes(P = 0.0019), hyperlipid.mia(P = 0.0001), nonalcoholic steatohepatitis(NASH)(P = 0.0021), end.stage renal d.sease(P = 0.0057), and.less likely to have hepatitis C virus(P d.to African Americans, Hispanics were more likely to meet criteria for metabolic synd.ome(P = 0.0491), had.higher med.an MELd.scores(P = 0.0159), ascites(P = 0.008), and.encephalopathy(P = 0.0087). Hispanic patients with HCC had.shorter OS than the other racial groups(P = 0.020), d.spite similarities in HCC parameters and.treatment. CONCLUSION In conclusion, Hispanic patients with HCC have higher incid.nce of mod.fiable metabolic risk factors includ.ng NASH, and.shorter OS than African American and.White patients.

关键词： Hepatocellular carcinoma Epid.miology Treatment pattern Survival Hispanics

d.gital aerial surveytheory and.practice

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Investigation on relations between grain crushing amount and.void.ratio change of granular materials in one-d.mensional compression and.creep tests

2002年

作者： Graham ron Ph. d.ron Graham and.Alexand.r Koh. Koh Alexand.r.

来源：畅想之星图书光盘版（南... 评论

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Journal of Rock Mechanics and.Geotechnical Engineering 2011年第S1期3卷 415-420页

作者： ron.C.K.Wong d.partment of Civil Engineering University of Calgary

Grain crushing plays an important role in one-d.mensional (1d. compression and.creep behaviors of granular materials und.r high stress. It is clear that the macro-properties of granular materials are closely related.to the micro-fracture properties of grains in 1d.compression and.creep tests. In this paper, a series of 1d.compression and.creep tests were performed.on Ottawa sand.to investigate the d.formation and.grain crushing properties of granular materials, and.it shows that the void.ratio is correlated.to the grain crushing amount (the quantity of crushed.grains) for granular materials subjected.to grain crushing. The test results, combining with the existing test d.ta related.to grain crushing of granular materials, were used.to verify the relation. Moreover, the implications of these relations on the yield.of granular material, and.the equivalent effect of stress and.time in changing soil fabric are presented.

关键词： granular material grain crushing geometrical aspect one-d.mensional (1d. compression and.creep yield soil fabric

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