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Analysis of the Cicatricial Acceleration Method (MAC®) in Skin Repair in Wistar Rattus norvegicus with Induced Chemical Burns

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Journal of Biosciences and Medicines 2024年第9期12卷 204-214页

作者： Marcus Vinicius de Mello Pinto Sandroval Francisco Torres Aline Ronis Sampaio Karin Yuri Fernandez Iturra Miriam Viviane Baron Patricia Froes Carlos ruiz da Silva Daiane Paza Maria Elena Silva Alvarez Josefa Jeanette Ugalde Juliano Tibola Esteban Fortuny Celulare Institute Petrpolis Brazil State University of Santa Catarina (UDESC) Florianopolis Brazil Bienus Clinic Santiago Chile Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Brazil International Research Group (IRG) Natal Brazil Academic Training Center (CTA) College So Paulo Brazil Fibrafisio Clinic Brusque Brazil Fisiocare Clinic Curic Chile Lua Clinic Coyhaique Chile Finis Terrae University Santiago Chile

Introduction: The cicatricial acceleration method (MAC®) promotes photobiological effects of an anti-inflammatory and healing nature. Its therapeutic radiation is emitted, producing photobiostimulant effects that result in rapid tissue repair and better tissue quality. The treatment of burns has always been a challenge, which involves both performing surgery and controlling and guiding scar regeneration, avoiding possible morbidities. Objective: To evaluate the effects of applying the MAC methodology with an AlGa (aluminum, gallium arsenide) laser on the time and quality of tissue repair in the skin of rats after induced chemical burns. Method: 22 adult male rats were subjected to a second-degree chemical burn on the back using 50% trichloroacetic acid. After the burns, the animals were randomly separated into 2 groups: control and experimental. The control group (G1) received placebo laser therapy and the laser group (G2) underwent laser irradiation with an energy density of 100 J/cm2. Histological analysis and macroscopic evaluation were carried out by means of the paper template method. Results: Group G1 showed (53%) of the necrosis area and group G2 showed (11%) necrosis area. Conclusion: The cicatricial acceleration method (MAC®) favored the repair of wounds caused by a 2nd-degree chemical burn, optimizing time and improving quality.

关键词： Chemical Burn Healing Scarring Cicatricial Acceleration Method (MAC®) Tissue Repair

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Transfer of an Aluminum Atom:An Avenue to Aluminum Heterocycles

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CCS Chemistry 2023年第9期5卷 2059-2068页

作者： Xin Zhang Hongyu Wang Xiaofang Lan Yanbo Mei david A.ruiz Liu Leo Liu Department of Chemistry and Guangdong Provincial Key Laboratory of Catalysis Southern University of Science and TechnologyShenzhen 518055

Synthetic chemistry enables constructing molecular complexity using simple substrates through simple *** disclose an unprecedented Al-atom transfer strategy for the synthesis of aluminum heterocycles with high atom *** strategy involves an effective cycloaddition of a free carbazolyl-aluminylene with unsaturated hydrocarbons,followed by facile cleavage of the N-Al *** aluminylene formally behaves as a tetra-active ambiphilic[Al+]cation transfer reagent in a two-step manner,and the only byproduct is a carbazolide salt that can be utilized to regenerate the *** carbazolyl Al-heterocycles show unique luminescent properties,in which one exhibits dual *** approach not only has a significant impact on the future design of single-atom addition reactions but also paves the way for emissive materials based on Al-heterocycles.

关键词： aluminum heterocycles atom transfer dual emission alumole aluminylene

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Allophane as a Nanotechnological Additive in Masonry Materials to Increase Resistance and Waterproofing

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Advances in Materials Physics and Chemistry 2024年第8期14卷 196-212页

作者： Edward H. Jiménez Joao Rivera Juan H. Villalba Paola E. Vera Marlon Cuenca Belén Granja Javier Fuentes Sandra Gavilanes Daniel Hidalgo Fernando Garcia Jose Bermudez Washington ruiz Alexis Martial Debut Facultad de Ingeniera Qumica Universidad Central del Ecuador Quito Ecuador Facultad de Arquitectura y Urbanismo Universidad Central del Ecuador Quito Ecuador Nanomaterials Characterization Laboratory Universidad de las Fuerzas Armadas ESPE Sangolqu Ecuador

The constant need for high-strength materials in the construction industry promotes the research of additives that improve the properties of masonry materials. The use of allophane as an additive in concrete and mortar mixtures was implemented to improve their strength and waterproofing, respectively, using compression and water absorption tests according to their corresponding standards (ASTM C1231, ASTM D2938, and ASTM C1585). The samples were evaluated at different concentrations and curing ages. In addition, different sand/cement ratios were considered for the mortar. The results revealed that there was a 9.4% increase in compressive strength in concrete and a 23.7% reduction in water absorption in mortar for the 5:1 ratio. These changes would be the result of the interaction of the nanoporous additive in the atomic crystal structure of the material demonstrating the nanotechnological nature of allophane.

关键词： Allophane Nano Additive Strength Impermeability Concrete Mortar

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Model of Mediating Determinants of Time Differences in INDYCAR

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Journalism and Mass Communication 2024年第4期14卷 232-240页

作者： Wilfrido Isidro Aldana Balderas Héctor Daniel Molina ruiz Enrique Martínez Muñoz Eleazar Villegas González Tirso Javier Hernández Gracia Arturo Sánchez Sánchez Cruz García Lirios Alfredo Barrera Escobar University of México HuehuetocaMèxico University of Hidalgo PachucaMèxico University of Tlaxcala Mèxico University of CDMX Mexico University of FV Mexico

The IndyCar series distinguishes itself by providing the same design and operation of the single-seater to its *** difference in times is then attributable to the skills of the drivers,but considering the data from the races could test this *** objective of this work was to establish a trajectory model to predict race times.A cross-sectional,correlational,and explanatory work was carried out with a sample of 18,474 records in the period from 2020 to 2023 of the IndyCar *** results show that the time span predicts the time *** relation to the studies of acceptance of the technology,the adjustment of this to human capacities to explain the time differences in the series of racing cars is discussed.

关键词： time differences ranking differences ranking race time laps completed

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Inexpensive and flexible nanographene-based electrodes for ubiquitous electrocardiogram monitoring

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npj Flexible Electronics 2019年第1期3卷 100-105页

作者： Francisco J.Romero Encarnacion Castillo Almudena Rivadeneyra Alejandro Toral-Lopez Markus Becherer Francisco G.ruiz Noel rodriguez Diego P.Morales Pervasive Electronics Advanced Research Laboratory University of Granada18071 GranadaSpain Department of Electronics and Computer Technology University of Granada18071 GranadaSpain Institute for Nanoelectronics Technische Universität München80333 MunichGermany Biochemistry and Electronics as Sensing Technologies Group University of Granada18071 GranadaSpain

Flexible electronics is one of the fundamental technologies for the development of electronic skin,implant wearables,or ubiquitous *** this context,graphene-derived materials have attracted great interest due to their unique properties to fulfill the demands of these *** we report a simple one-step method for the fabrication of electrophysical electrodes based on the photothermal production of porous nanographene structures on the surface of flexible polyimide *** approach constitutes an inexpensive alternative to the commercial medical electrodes,leading to a lower and much more stable skin–electrode contact resistance and providing comparable signal *** technology has been framed inside the IoT paradigm through the development of a denoising and signal classification clustering algorithm suitable for its implementation in wearable *** experiments have shown promising achievements regarding noise reduction,increasing the crest factor~3.7 dB,as well as for the over 90%heart rate-monitoring accuracy.

关键词： ubiquitous IoT electrodes

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Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy

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World Journal of Gastroenterology 2016年第17期22卷 4397-4402页

作者： Andrés Duarte-Rojo Astrid ruiz-Margáin Ricardo U Macias-rodriguez Francisco Javier Cubero José Estradas-Trujillo Rosa Ma Munoz-Fuentes Aldo Torre University of Arkansas for Medical Sciences Little Rock AR 72205 United States Department of Gastroenterology Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Mexico City 14000 Mexico Department of Internal Medicine III University Hospital RWTH Aachen 52074 Aachen Germany Department of Immunology Complutense University School of Medicine 28040 Madrid Spain

AIM: To evaluate the association between serum concentrations of S100β in patients with cirrhosis and the presence of low grade hepatic encephalopathy (HE).METHODS: This was a cross-sectional study. The population was categorized into four groups healthy subjects, cirrhosis without HE, cirrhosis with covert hepatic encephalopathy (CHE) and cirrhosis with overt HE. Kruskal-Wallis, Mann Whitney’s U with Bonferroni adjustment Spearman correlations and area under the ROC were used as ***: A total of 61 subjects were included, 46 cirrhotic patients and 15 healthy volunteers. S100β values were different among all groups, and differences remained significant between groups 1 and 2 (P 0.13 ng/mL as the best cutoff value of S100β for the diagnosis of HE (sensitivity 83.3%, specificity 63.6%).CONCLUSION: Serum concentrations of S100β are higher in patients with cirrhosis than in healthy volunteers, and are further increased in the presence of hepatic encephalopathy. The results suggest that serum biomarkers such as S100β could help in the correct characterization of incipient stages of HE.

关键词： Hepatic encephalopathy S100β protein Astrocyte Psychometric hepatic encephalopathy score Critical flicker frequency

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Arrhythmias in Common Arterial Trunk(CAT):Uncommon Atrial Tachycardia in CAT with Anomalous Pulmonary Venous Connection and Re-entry Atrial Tachycardia in CAT with HIV Seropositive Mother

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Congenital Heart Disease 2021年第4期16卷 417-425页

作者： Elio Caruso Silvia Farruggio davide Calvaruso Corrado Di Mambro david Angel Ortiz ruiz Salvatore Agati Rafie Khoargami Mediterranean Pediatric Cardiology Center“Bambino Gesù” San Vincenzo HospitalTaorminaItaly Cardiac Electrophysiology Research Center RajaieUniversity of Medical SciencesTehranIran

We show a brief report of two common arterial trunk cases(CAT)with different arrhythmias and discuss anatomy,clinical and diagnostic *** burden of volume and pressure overload of this cardiac malformation may predispose to different types of arrhythmia before and after surgical *** of labile hemodynamic state in this group of patients,prompt diagnosis of any arrhythmia is mandatory as the devastating factor on *** first patient with a diagnosis of CAT Type II Collett and Edwards(CE)had a particular history with HIV seropositive mother assuming antiretroviral therapy during pregnancy,who presented hyperbilirubinemia and liver dysfunction at birth,and re-entry atrial tachycardia after *** second patient had CAT Type I CE with a partial anomalous venous connection of left superior pulmonary vein and uncommon type of atrial tachycardia with dual AV nodal physiology.

关键词： Common arterial trunk arrhythmia anomalous pulmonary venous connection HIV

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Biliary cystadenoma

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World Journal of Gastroenterology 2009年第28期15卷 3573-3575页

作者： Miguel A Hernandez Bartolome Sagrario Fuerte ruiz Israel Manzanedo Romero Beatriz Ramos Lojo Ignacio rodriguez Prieto Luis Gimenez Alvira Rosario Granados Carreo Manuel Limones Esteban General and Digestive System Surgery Service University Hospital of Getafe General and Digestive System Surgery Service Parla Hospital General and Digestive System Surgery Service Puerta de Hierro Hospital Pathologycal Anathomy ServiceUniversity Hospital of Getafe

The diagnosis of cystadenoma is rare, even more so when located in the extrahepatic bile duct. Unspecific clinical signs may lead this pathology to be misdiagnosed. The need for pathological anatomy in order to distinguish cystadenomas from simple biliary cysts is crucial. The most usual treatment nowadays is resection of the bile duct, together with cholecystectomy and Roux-en-Y reconstruction.

关键词： Cystadenoma Extrahepatic bile duct tumors Choledochal cyst Jaundice Biliary surgery

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COVID-19 impact in Crohn’s disease patients submitted to autologous hematopoietic stem cell transplantation

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World Journal of Hematology 2024年第1期11卷 1-8页

作者： Milton Artur ruiz Roberto Luiz Kaiser Junior Lilian Piron-ruiz Tainara Souza Pinho Lilian Castiglioni Luiz Gustavo de Quadros Department of Bone Marrow Transplantation Associação Portuguesa de BeneficênciaSão Josédo Rio Preto SP 15090470Brazil Department of Surgery Kaiser Hospital DiaSão Josédo Rio Preto 08010-150São PauloBrazil Department of Bone Marrow Transplantation Beneficência Portuguesa HospitalSão Josédo Rio Preto 15090470São PauloBrazil FAMERP Faculdade de Medicina de São Josédo Rio PretoSão Josédo Rio Preto 15090000São PauloBrazil Beneficência Portuguesa Hospital ABC Medical SchoolSão Bernardo 15015110São PauloBrazil

BACKGROUND Severe acute respiratory syndrome coronavirus 2 is the virus responsible for coronavirus disease 2019(COVID-19),a disease that has been blamed for inducing or exacerbating symptoms in patients with autoimmune ***'s disease(CD)is an inflammatory bowel disease that affects genetically susceptible patients who develop an abnormal mucosal immune response to the intestinal *** who underwent hematopoietic stem cell transplantation(HSCT)are considered at risk for *** To describe for the first time the impact of COVID-19 in CD patients who had undergone autologous,non-myeloablative *** In this descriptive study a series of 19 patients were diagnosed with positive *** two patients there were reports of the occurrence of two infectious *** related to HSCT,such as time elapsed since the procedure,vaccination status,CD status before and after infection,and clinical manifestations resulting from COVID-19,were *** Among the patients with COVID-19,three,who underwent Auto HSCT less than six months ago,relapsed and one,in addition to the CD symptoms,started to present thyroid impairment with positive *** one of the patients required hospitalization for five days to treat COVID-19 and remained in CD clinical *** patients reported late symptoms that may be related to *** were no deaths,and a statistical evaluation of the series of COVID-19 patients compared to those who did not present any infectious episode did not identify significant differences regarding the analyzed *** Despite the change in CD status in three patients and the presence of nine patients with late symptoms,we can conclude that there was no significant adverse impact concerning COVID-19 in the evaluated patients who underwent HSCT to treat CD.

关键词： Inflammatory bowel disease Crohn disease SARS-CoV-2 COVID-19 Autologous hematopoietic stem cell transplantation Stem cell therapy

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In vitro germination and shoot proliferation of the threatened species Cinchona officinalis L(Rubiaceae).

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Journal of Forestry Research 2016年第6期27卷 1229-1236页

作者： Rosa Armijos-Gonzalez Cesar Perez-ruiz Departamento de Ciencias Naturales Universidad Tecnica Particular de LojaCP 1101 608 LojaEcuador Departamento de Biotecnologia y Biologia Vegetal E.T.S.Ingenieros AgronomosUniversidad Politecnica de MadridCP 728040 MadridSpain

Cinchona officinalis （Rubiaceae） is an endemic species of the Loja Valley in southern Ecuador with medicinal uses. Because of over-exploitation in the nine- teenth century and more recent disturbances to its ecosystem, C. officinalis populations are threatened. Currently, natural regeneration of the populations is low, despite its high plant regeneration and seed formation capacity. In the present study, an efficient protocol for germination, shoot proliferation and plantlets regeneration was developed for this species. Phenolic content and germination rate of C. officinalis seeds were compared with a control species, C. pubescens. Nodal segments from seedlings of C. officinalis were cultured on Gamborg medium supplemented with different combinations of plant growth regulators. Because the phenol content is high in C. officinalis, the phenolic should be removed with hydrogen peroxide or water washes to stimulate germination. Shoots and callus developed from nodal segments within 45 days using most of the tested combinations of plant growth regulators. The best rates of shoot proliferation, callus formation and adventitious buds were obtained in medium supplemented with 5.0 mg L^-1 6-benzyl-aminopurine and 3.0 mg L^-1 indole- 3-butyfic acid.

关键词： Callus Cinchona officinalis Germination Phenols Rubiaceae Shoot

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