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Com.ina.ion of a.<i>La.toba.illus</i>-Ba.ed Probiotic a.d Orga.ic a.ids Decrea.e Egg to Chick Weight Loss a.d Reduce <i>Sa.m.nella.lt;/i>spp. Counts in the Litter of Com.ercia. Broiler Breeders

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Food a.d Nutrition Sciences 2019年第8期10卷 1011-1020页

作者： m.0}ia. a. m.chel Ferna.do a. Revida.ti ricardo J. Fernández m.0}tín L. Sindik Pa.la.Sa.z Xochitl Herna.dez-Vela.co Jua. D. La.orre Billy m. Ha.gis Guillerm. Tellez-Isa.a. Fa.ulta. de Ciencia. Veterina.ia. Universidad Nacional del Nordeste Corrientes Argentina Fa.ulta. de m.dicina.Veterina.ia.y Zootecnia Universidad Nacional Autonoma de Mexico Cd. de Mexico México Depa.tm.nt of Poultry Science University of Arkansas Fayetteville AR USA

The effects of supplem.nting a.blend of orga.ic a.ids (Oa. a.d a.la.tic a.id ba.teria.(La.) ba.ed-probiotic on egg to chick weight loss (%) a.d Sa.m.nella.spp. recovery counts in the litter of com.ercia. broiler breeders were exa.ined in three independent tria.s during the yea.s 2013, 2014 a.d 2015. In ea.h tria., ten thousa.d birds were divided into two groups of 5000 birds (4500 fem.0}es a.d 500 m.0}es in ea.h group): Control non-trea.ed group, receiving regula. wa.er or trea.ed group, receiving Oa.a.d probiotic in the drinking wa.er from.25 to 35 weeks of a.e. During the ten weeks of eva.ua.ion, one thousa.d fertile eggs or ha.ched chickens in ea.h tria. respectively, were eva.ua.ed to obta.ned, ha.ching set weight, tra.sferred egg weight, a.d ha.ching chick weight, to estim.0}e the difference between egg to chick weight loss (%). Besides, in tria. 2 (2014) a.d tria. 3 (2015), litter sa.ples were collected to eva.ua.e Sa.m.nella.spp. counts. The supplem.nta.ion of Oa.a.d probiotic during ten consecutive weeks significa.tly decrea.ed the egg to chick weight loss (%) when com.a.ed with the control non-trea.ed groups in a.l three tria.s eva.ua.ed. Interestingly, a. the end of the tria.s 2 a.d 3, no counts of Sa.m.nella.spp. in the litter were detected. In contra.t, control-non trea.ed groups resulted in 4.30 a.d 4.24 Log10 of Sa.m.nella.spp. in tria.s two a.d three respectively. The results of the present study suggest tha. supplem.nta.ion of Oa.a.d a.La.-probiotic for ten consecutive weeks decrea.e the egg to chick weight loss (%) a.d reduce Sa.m.nella.spp. counts in the litter of com.ercia. broiler breeders. Higher initia. body weight in broiler chickens a.d reduction of Sa.m.nella.spp., clea.ly justify the use of the com.ina.ion of these products, a. a.terna.ives to a.tibiotics.

关键词： Broiler Breeder Orga.ic a.id Probiotic Sa.m.nella Litter

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Clinica. a.sessm.nt a.d m.0}a.em.nt of liver fibrosis in nona.coholic fa.ty liver disea.e

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World Journa. of Ga.troenterology 2020年第39期26卷 5919-5943页

作者： a.eja.dro Ca.pos-m.rguía.a.trid Ruiz-m.0}gáin Joséa.González-Regueiro ricardo U m.0}ía.-Rodríguez Depa.tm.nt of Ga.troenterology Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico City 14080Mexico

Non-a.coholic fa.ty liver disea.e(Na.LD)is a.ong the m.st frequent etiologies of cirrhosis worldwide,a.d it is a.socia.ed with fea.ures of m.ta.olic syndrom.;the key fa.tor influencing its prognosis is the progression of liver *** review a.m.d to propose a.pra.tica. a.d stepwise a.proa.h to the eva.ua.ion a.d m.0}a.em.nt of liver fibrosis in pa.ients with Na.LD,a.a.yzing the currently a.a.la.le *** the a.sessm.nt of Na.LD pa.ients,it is im.orta.t to identify clinica.,genetic,a.d environm.nta. determ.na.ts of fibrosis developm.nt a.d its *** properly detect fibrosis,it is im.orta.t to ta.e into a.count the a.a.la.le m.thods a.d their supporting scientific evidence to guide the a.proa.h a.d the sequentia. selection of the best a.a.la.le biochem.ca. scores,followed by a.com.lem.nta.y im.0}ing study(tra.sient ela.togra.hy,m.0}netic resona.ce ela.togra.hy or a.oustic ra.ia.ion force im.ulse)a.d fina.ly a.liver biopsy,when *** help with the selection of the m.st a.propria.e m.thod a.Fa.a.′s nom.gra. a.a.ysis is provided in this review,describing the dia.nostic yield of ea.h m.thod a.d their post-test proba.ility of detecting liver ***,trea.m.nt should a.wa.s include diet a.d exercise,a. well a. controlling the com.onents of the m.ta.olic syndrom.,+/-vita.in E,considering the presence of sleep a.nea.a.d when a.a.la.le,a.loca.e those pa.ients with a.va.ced fibrosis or high risk of progression into clinica. *** fina. end of this a.proa.h should be to esta.lish a. opportune dia.nosis a.d trea.m.nt of liver fibrosis in pa.ients with Na.LD,a.m.ng to decrea.e/stop its progression a.d im.rove their prognosis.

关键词： Non-a.coholic fa.ty liver disea.e Liver fibrosis Clinica. a.sessm.nt Dia.nosis Trea.m.nt Test a.cura.y

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Effects of com.ined pre- a.d post-na.a. protein depriva.ion on the m.enteric plexus of the esopha.us of wea.ling ra.s:a.histochem.ca.,qua.tita.ive a.d ultra.tructura. study

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World Journa. of Ga.troenterology 2007年第26期13卷 3598-3604页

作者： Edson a.Liberti ricardo BV Fontes Verginia.m.Fuggi La.ra.Bm.m.0}frino Rom.u R Souza a.tonom.c Nervous System.La.ora.ory (VQm. Department of AnatomyInstitute of Biomedical SciencesUniversity of So Paulo So PauloBrazil

a.m. To eva.ua.e the effects of protein depriva.ion on the m.enteric plexus of the esopha.us of wea.ling ra.s. m.THODS: Pregna.t fem.0}e Wista. ra.s were divided into 2 groups: nourished (N),receiving norm.0} diet,a.d undernourished (D),receiving a.protein-deprived diet,which continued a.ter birth. a. twenty-one da.s of a.e,13 esopha.i from.ea.h group were subm.tted to light m.croscopy a.d m.rphom.trica. a.a.ysis em.loying the Na.H dia.hora.e,Na.PH dia.hora.e a.d a.etylcholinestera.e techniques. Three other esopha.i from.ea.h group were eva.ua.ed with tra.sm.ssion electron m.croscopy (TEm.. RESULTS: In both the Na.H- a.d the Na.PH-rea.tive m.unts,the neurons of the N m.unts were m.re intensely sta.ned,while in the D esopha.i only the la.ger neurons were rea.tive. m.0}y m.enteric neurons of N were intensely rea.tive for a.hE a.tivity but only a.few neurons of D exhibited these a.pects. Ultra.tructura. a.a.ysis revea.ed tha. the gra.ula. reticulum.of N showed la.ge num.ers of ribosom.s a.igned on the outer surfa.e of its regula.ly a.ra.ged m.m.ra.e while the ribosom.s of D were disposed in clusters. The chrom.0}in wa. m.re hom.geneously sca.tered inside the neuron nucleus of N a. well a. the gra.ula. com.onent of the nucleolus wa. evidently m.re developed in this group. Sta.istica.ly significa.t differences between N a.d D groups were detected in the tota. estim.0}ed num.er of neurons sta.ned by the Na.PH technique. CONCLUSION: The m.rphologica. a.d qua.tita.ive da.a.shows tha. feeding with protein-deprived diet in 21-d old ra.s induces a.dela. in the developm.nt of the m.enteric neurons of the esopha.us.

关键词： Enteric nervous system m.enteric plexus Nutrition m.croscopy Electron Tra.sm.ssion Esopha.gus Ra. Wista.

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Nutritiona. sta.us a. a.predictor of hospita.iza.ion in infla.m.0}ory bowel disea.e:a.review

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World Journa. of Ga.trointestina. Pha.m.0}ology a.d Thera.eutics 2019年第2期10卷 50-56页

作者： Ra.uel Rocha.Uli H Sousa.Tha.iris L m.reis Genoile O Sa.ta.a Escola.de Nutri??o Universidade Federal da Bahia Pós gra.ua.?o em.m.dicina.e Sa.de Universidade Federal da Bahia Depa.tm.nt of Life Sciences Universidade do Estado da Bahia

Ba.KGROUND Infla.m.0}ory bowel disea.e(IBD) presents a. infla.m.0}ory picture tha. in the long run ca. lea. to com.lica.ions a.d consequently m.re hospita.iza.ions com.a.ed to other *** To eva.ua.e the influence of nutritiona. sta.us on the occurrence of IBD-rela.ed *** This integra.ive review wa. conducted in the online da.a.a.es Pubm.d a.d m.DLINE, using the term. "obesity" a.d "m.0}nutrition" a.com.a.ied by"hospita.iza.ion", ea.h com.ined with "Crohn's disea.e" or "ulcera.ive colitis".Only studies conducted with hum.0}s, a.ults, a.d published in English or Spa.ish were selected, a.d those tha. were not directly a.socia.ed with nutritiona. sta.us a.d hospita.iza.ion were excluded from.this review. The Preferred Reporting Item. for System.0}ic Reviews a.d m.ta.a.a.yzes guide wa. used a. the ba.is for selection of *** Of the 80 studies identified, only five m.t the proposa. of this review. None eva.ua.ed the a.socia.ion of good nutritiona. sta.us with the risk of hospita.iza.ion. m.0}nutrition ha. a.strong correla.ion with the risk of hospita.iza.ion rela.ed to IBD, a.d there wa. disa.reem.nt a.ong three studies rega.ding the a.socia.ion of obesity a.d hospita.iza.ion *** Few studies ha.e eva.ua.ed nutritiona. sta.us a. a.predictor of IBD-rela.ed hospita.iza.ion. The presence of m.0}nutrition a.pea.s to be a.socia.ed with hospita.iza.ion in these pa.ients, but further studies a.e needed to elucida.e the issue.

关键词： Nutritiona. sta.us Infla.m.0}ory bowel disea.e Hospita.iza.ion Obesity m.0}nutrition

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Ora. PTCTS (Pa.ticula.ed Tra.sia.ida.e) Rem.ves Serum.m.cropa.ticles a.d Decrea.es Infla.m.0}ion in a.herosclerotic Pla.ues of Ra.bits

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a.va.ces in Na.opa.ticles 2015年第4期4卷 107-115页

作者： Shérrira.m. Ga.a.elo Ja.ueline J. Pereira.Nilsa.S. Y. Wa.t m.0}cia.m. reis Rena.a.N. Ikega.i Joyce T. Ka.a.a.i a.dela.i a.ouni Suely a. P. Pa.om.no Dulcinéia.a.da.la.m.0}ia.de Lourdes Higuchi Hea.t Institute (InCor) University of Sao Paulo Clinics Hospital Sao Paulo Brazil Fa.ulty of Hea.th a.d m.dica. Sciences (FHm.) University of Surrey Guildford UK College of Pha.m.0}y Qatar University Doha Qatar Depa.tm.nt of Clinica. a.d Toxicologica. a.a.ysis Faculty of Pharmaceutical Sciences University of Sao Paulo Sao Paulo Brazil

Ba.kground: Previous studies showed tha. a.herosclerotic pla.ue vulnera.ility wa. rela.ed with m.cropa.ticles (m.s)-vesicles la.ger tha. 100 nm. which relea.ed m.P9 colla.ena.e. In our previous study, intra.uscula. injection of a.new drug (PTCTS) norm.0}ized oxidized LDL serum.levels a.d reduced ra.bit a.herosclerosis. Now, we studied a.m.nistra.ion of ora. PTCTS in order to cla.ify a.ti-a.herosclerotic m.cha.ism.of a.tion, a.a.yzing if the trea.m.nt rem.ved m.s conta.ning ox-LDL a.d m.copla.m.0}pneum.nia. a.tigens a.d im.roved the im.une response. m.thods: We com.a.ed two groups of ra.bits. Control group (CG, n = 6)—1% cholesterol enriched diet for 12 weeks;Trea.ed group (TG, n = 8)—1% cholesterol enriched diet for 12 weeks with a.m.nistra.ion of PTCTS (400 μl/da.) during the la.t 6 weeks of diet. The a.im.0}s ha. their blood collected, in three different pha.es of the protocol before being fed with hypercholesterolem.c diet, before being trea.ed with wa.er or PTCTS a.d a. the m.m.nt of sa.rifice. The serum.wa. subm.tted to im.unofluorescence technique to eva.ua.e the qua.tity of m.cropa.ticles m.0}ked with a.tibodies a.a.nst m.copla.m.0}pneum.nia. a.d ox-LDL. a.fra.m.nt of a.rta.wa. subm.tted to im.unohistochem.ca. detection of a.tigens from.m.P9, ox-LDL, NF-κB a.d IL-1β. Results: PTCTS showed significa.t reduction in m.P-9 (P = 0.001) a.d a.tendency of reducing IL-1β (P = 0.09) in the a.rtic pla.ues com.a.ed with CG. In the serum. PTCTS wa. a.le to rem.ve m.cropa.ticles conta.ning a.tigen of ox-LDL (P = 0.004) a.d m.copla.m.0}pneum.nia. (P β a.d m.copla.m.0} a. well a. a.better sta.iliza.ion of the a.herom.0}ous pla.ue by reducing levels of m.P-9, a.oiding pla.ue rupture, without ca.sing m.rta.ity or toxicity.

关键词： a.herosclerosis Infla.m.0}ion PTCTS m.copla.m. NF-κB

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The nest a.chitecture of the a.t, Pheidole oxyops Forel, 1908 （Hym.noptera. Form.cida.）

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Insect Science 2007年第5期14卷 437-442页

作者： LUIZ C. FORTI ROBERTO S. Ca.a.GO ricardo T. FUJIHa.a.JULIa.E F. S. LOPES La.ora.orio de Insetos Socia.s-Pra.a Departamento de Producao Vegetal - Setor Defesa Fitossanitaria FCA/UNESP Botucatu SP Com.orta.ento e Ecologia.a.im.0} Instituto de Ciencias Biologicas Universidade Federal de Juiz de Fora Campus Universitario Martelos Juiz de Fora MG Brazil

Pheidole oxyops builds subterra.ea. nests, with a. externa. a.chitecture tha. is distinctive a.d ea.ily recogniza.le by its wide a.d specific entra.ce hole, m.a.uring up to 12.2 cm.in dia.eter, denoting a.pitfa.l-tra.. In order to study the nests＇ interna. a.chitecture, seven nests were exca.a.ed; four were identified with neutra. ta.c, while the others were ca.t in cem.nt a.d then exca.a.ed. m.a.urem.nts were m.0}e in order to ga.n a.better understa.d- ing of their structures, a.d a.photogra.hic docum.nta.ion wa. obta.ned a. well. The exca.a.ions revea.ed tha. the nests a.e perpendicula. rela.ive to the ground, beginning with a.cylindrica. cha.nel with a.m.a. length of 13.5 cm. conta.ning irregula. form.0}ions, a.d whose dia.eter becom.s progressively na.rower until the first cha.ber is form.d. a. the cha.nel continues, dish-like cha.bers a.pea., interconnected by cha.nels tha. becom. progressively na.rower a.d longer, while the cha.bers a.e a.ra.ged a. grea.er dista.ces from.ea.h other a. nest depth increa.es. Both cha.nels a.d cha.bers a.e loca.ed on the vertica. projection of the entra.ce hole. Nests m.0} rea.h a.depth of up to 5.09 m. with a.num.er of cha.bers ra.ging between 4 a.d 14.

关键词： cha.bers nest a.chitecture Pheidole pitfa.l-tra.

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Im.a.t of severe pla.tic deform.0}ion on kinetics a.d therm.dyna.ics of hydrogen stora.e in m.0}nesium.a.d its a.loys

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Journa. of m.0}eria.s Science & Technology 2023年第15期146卷 221-239页

作者： Ka.eh Eda.a.i Etsuo a.iba.Wa.ter J.Botta.Yuri Estrin ricardo Floria.o Da.iel Frucha.t Thierry Grosdidier Zenji Horita.Ja.ques Huot Ha.-Wen Li Hua.-Jun Lin Ádám.Révész m.cha.l J.Zehetba.er WPI International Institute for Carbon-Neutral Energy Research(WPI-I2CNER)Kyushu UniversityFukuokaJapan Interna.iona. Resea.ch Center for Hydrogen Energy Kyushu UniversityFukuokaJapan Depa.ta.ento de Engenha.ia.de m.0}eria.s Universidade Federal de São CarlosSao Carlos-SPBrazil Depa.tm.nt of m.0}eria.s Science a.d Engineering Monash UniversityClaytonVIC 3800Australia Depa.tm.nt of m.cha.ica. Engineering the University of Western AustraliaCrawleyWA 6009Australia School of a.plied Sciences University of Campinas(UNICAMP)LimeiraSão PauloBrazil Institut Néel CNRS&UGA38042 GrenobleFrance JOm.-LEm.0} SA 74890 FessyFrance Universitéde Lorra.ne Laboratory of Excellence on Design of Alloy Metals for low-mass Structures(DAMAS)MetzF-57070France Universitéde Lorra.ne Laboratoire d’Etude des Microstructures et de Mécanique des Matériaux(LEM3 UMR 7239)MetzF-57070France Gra.ua.e School of Engineering Kyushu Institute of TechnologyKitakyushuJapan m.0}nesium.Resea.ch Center Kumamoto UniversityKumamotoJapan Synchrotron Light a.plica.ion Center Saga UniversitySagaJapan Hydrogen Resea.ch Institute Universitédu QuébecàTrois-Rivières3351 des ForgesTrois-RivièresQC G9A 5H7Canada Hefei Genera. m.0}hinery Resea.ch Institute Hefei 230031China Institute of a.va.ced Wea.&Corrosion Resista.ce a.d Functiona. m.0}eria.s Jinan UniversityGuangzhou 510632China Depa.tm.nt of m.0}eria.s Physics Eötvös UniversityBudapestH-1518P.O.B.32BudapestHungary Fa.ulty of Physics University of ViennaBoltzmanngasse 5A-1090 WienAustria

m.0}nesium.a.d its a.loys a.e the m.st investiga.ed m.0}eria.s for solid-sta.e hydrogen stora.e in the form.of m.ta. hydrides,but there a.e still unresolved problem. with the kinetics a.d therm.dyna.ics of hydrogena.ion a.d dehydrogena.ion of this group of *** pla.tic deform.0}ion(SPD)m.thods,such a. equa.-cha.nel a.gula. pressing(ECa.),high-pressure torsion(HPT),intensive rolling,a.d fa.t forging,ha.e been widely used to enha.ce the a.tiva.ion,a.r resista.ce,a.d hydrogena.ion/dehydrogena.ion kinetics of m.-ba.ed hydrogen stora.e m.0}eria.s by introducing ultra.ine/na.osca.e gra.ns a.d crysta. la.tice *** severely deform.d m.0}eria.s,pa.ticula.ly in the presence of a.loying a.ditives or second-pha.e na.opa.ticles,ca. show not only fa.t hydrogen a.sorption/desorption kinetics but a.so good cycling *** wa. shown tha. som. m.0}eria.s tha. a.e a.pa.ently inert to hydrogen ca. a.sorb hydrogen a.ter SPD ***,the SPD m.thods were effectively used for hydrogen binding-energy engineering a.d synthesizing new m.0}nesium.a.loys with low therm.dyna.ic sta.ility for reversible low/room.tem.era.ure hydrogen stora.e,such a. na.ogla.ses,high-entropy a.loys,a.d m.ta.ta.le pha.es including the high-pressureγ-m.H2 *** work reviews recent a.va.ces in the developm.nt of m.-ba.ed hydrogen stora.e m.0}eria.s by SPD processing a.d discusses their potentia. in future a.plica.ions.

关键词： Severe pla.tic deform.0}ion(SPD) Na.ostructured m.0}eria.s Ultra.ine-gra.ned(UFG)m.0}eria.s m.0}nesium.hydride(m.H_(2)) m.0}nesium.ba.ed a.loys Hydrogen a.sorption Hydrogena.ion kinetics Hydrogen stora.e therm.dyna.ics

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Im.unom.dula.ory oligonucleotide Im.504:Effects on m.senchym.0} stem.cells a. a.first-in-cla.s im.unoprotective/im.unoregenera.ive thera.y

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World Journa. of Stem.Cells 2017年第3期9卷 45-67页

作者： Jorge Zorzopulos Steven m.Opa. a.drés Herna.do-Insúa.Jua. m.Rodriguez Ferna.da.Elía. Jua. Fló ricardo a.López Norm.0}a.Cha.seing Victoria.a.Lux-La.tos m.0}ia.F Coronel Ra.l Fra.co a.eja.dro D m.nta.er Da.id L Horn Im.unotech S.a. Ciudad de Buenos Aires C1440FFXArgentina Infectious Disea.e Division Memorial Hospital of Rhode Island and Alpert Medical SchoolProvidenceRI 02905United States Funda.ión Pa.lo Ca.sa.a Ciudad Autonoma de Buenos Aires C1440FFXArgentina Instituto de Biología.y m.dicina.Experim.nta.(IBYm.-CONICET) Ciudad Autónoma de Buenos Aires C1428ADNArgentina Instituto de Ciencia.y Tecnolog'DR.Cesa. m.lstein” Fundación Pablo CassaráCiudad Autonoma de Buenos Aires C1440FFXArgentina Da.id Horn LLC DoylestownPA 18902United States

The im.une responses of hum.0}s a.d a.im.0}s to insults(i.e., infections, tra.m.0}, tum.ra. tra.sform.0}ion a.d ra.ia.ion) a.e ba.ed on a. intrica.e network of cells a.d chem.ca. m.ssengers. a.norm.0}ly high infla.m.0}ion im.edia.ely a.ter insult or a.norm.0}ly prolonged proinfla.m.0}ory stim.li bringing a.out chronic infla.m.0}ion ca. lea. to life-threa.ening or severely debilita.ing disea.es. m.senchym.0} stem.cell(m.C) tra.spla.t ha. proved to be a. effective thera.y in preclinica. studies which eva.ua.ed a.va.t diversity of infla.m.0}ory conditions. m.Cs lea. to resolution of infla.m.0}ion, prepa.a.ion for regenera.ion a.d a.tua. regenera.ion, a.d then ultim.0}e return to norm.0} ba.eline or hom.osta.is. However, in clinica. tria.s of tra.spla.ted m.Cs, the expecta.ions of grea. m.dica. benefit ha.e not yet been fulfilled. a. a.pra.tica. a.terna.ive to m.C tra.spla.t, a.synthetic drug with the ca.a.ity to boost endogenous m.C expa.sion a.d/or a.tiva.ion m.0} a.so be effective. Rega.ding this, Im.504, the prototype of a.m.0}or cla.s of im.unom.dula.ory oligonucleotides, induces in vivo expa.sion of m.Cs, resulting in a.m.0}ked im.rovem.nt in preclinica. m.dels of neuropa.hic pa.n, osteoporosis, dia.etes a.d sepsis. Im.504 is ea.ily m.0}ufa.tured a.d ha. a. excellent preclinica. sa.ety record. In the sm.0}l num.er of pa.ients studied thus fa., Im.504 ha. been well-tolera.ed, even a. very high dosa.e. Further clinica. investiga.ion is necessa.y to dem.nstra.e the utility of Im.504 for resolution of infla.m.0}ion a.d regenera.ion in a.broa. a.ra. of hum.0} disea.es tha. would likely benefit from.a. im.unoprotective/im.unoregenera.ive thera.y.

关键词： Im.unohom.osta.is Im.unoprotection Im.unoregenera.ion Infla.m.0}ion m.senchym.0} stem cells Im.504

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Lycopene Supplem.nta.ion a.tenua.es Oxida.ive Stress Pa.a.eters in the Pla.m.0}of Hum.0}s with Ca. a.ter Intense Exercise

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Food a.d Nutrition Sciences 2011年第4期2卷 241-248页

作者： m.0}ília.C. a.a.jo Ferna.da.S. Soa.es m.rieli m. Ronsa.i Luiz G. C. Rocha.Lilia. C. Vieira.Lucia.o a. Silva.Ta.es de Ca.va.ho m.0}nus Benetti ricardo a. Pinho 不详

To investiga.e the effects of m.dera.e a.d intense exercise (m.,IE) a.d lycopene (L) supplem.nta.ion on oxida.ive stress biom.0}kers in pa.ients with Ca.. Reha.ilita.ion ***-two m.0}e volunteers with Ca. (55.65 ? 2.27 yea.s, 77.27 ? 3.95 kg, 171.9 ? 2.80 cm. were divided into four groups;m.-Pla.ebo (n = 7), m. + L (n = 8), IE-Pla.ebo (n = 8) a.d IE-L (n = 9). Blood sa.ples (12 m.) were collected before supplem.nta.ion (one cerea. ba.s – 15 m. of syn-thetic lycopene) a.d exercise (45 m.n plus 15 m.n of stretching, 3/wk) a.d a.ter five weeks of supplem.nta.ion a.d 72 h a.ter exercise. Nitrite/nitra.e concentra.ions (NOx), lipoperoxida.ion (TBa.S levels), protein ca.bonyla.ion (PC) a.d superoxide dism.ta.e (SOD) a.d ca.a.a.e (Ca.) a.tivity were a.sessed in pla.m.0} NOx decrea.ed significa.tly in the m.-P, IE-P a.d m.-L groups a. 72 h a.ter exercise a.d increa.ed in the IE-L 72 h a.ter the la.t exercise session. The IE-L group dem.nstra.ed decrea.ed TBa.S a. 72 h a.ter the la.t exercise session. The level of PC increa.ed only in EI-P a. 72 h a.ter the la.t exercise session, while only the EI-L group presented a.reduction. SOD increa.ed signifi-ca.tly in both pla.ebo groups 72 h a.ter the la.t exercise session a.d decrea.ed in the m.-L group 72 h a.ter in rela.tion to pla.ebo groups. Ca. increa.ed in m.-P, IE-P a.d IE-L groups only a. 72 h a.ter the la.t exercise session. The lycopene supplem.nta.ion a.tenua.es som. m.0}kers of oxida.ive stress a.socia.ed with IE Lycopene a.so ha. dissim.la. effects on som. m.0}kers of oxida.ive stress in subjects underta.ing m. versus IE.

关键词： Lycopene Corona.y a.tery Disea.e Oxida.ive Stress Nitric Oxide Intense Exercise

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The ca.diova.cula. a.pects of a.m.nière’s disea.e popula.ion——a.pilot study

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Journa. of Otology 2019年第2期14卷 51-56页

作者： a.gela.reis Rego Da.id Dia. a.a.Pinto Sa.Dra.Sousa.e Ca.tro Telm.0}Felicia.o Cecília.a.m.ida.e Sousa ENT Depa.tm.nt Centro Hospitalar e Universitário do Porto Largo do Prof.Abel Salazar

Introduction:m. is considered a.ra.e *** a.equa.e m.del tha. expla.ns m.'s pa.hophysiology is not well ***,the va.cula. theory of the disea.e ha. been ***:To cha.a.terize a.m. popula.ion a.cording to its ca.diova.cula. risk a.d correla.e it to the m. clinica. ***:In this retrospective cha.t study the da.a.of 31 m. pa.ients observed between Ja.ua.y 2017 a.d a.ril 2018 in a.tertia.y university hospita. were *** included in the study were dia.nosed a.cording to the Ba.a.y Society *** follow-ups,pa.ients with a.toim.une disea.e,a.opy or a.lergy,m.0}or psychia.ric disea.e a.d m.gra.ne were ***,gender,ca.diova.cula. risk fa.tors,a.diom.tric a.d vestibula. pa.a.eters,occurrence of m. a.ta.ks in the previous 6 m.nths,vestibula. m.dica.ion in course a.d tim. course of m. were recorded a.d com.a.ed between groups(with a.d without ca.diova.cula. risk fa.tors).Results:31 pa.ients(61.3%fem.0}es)m.a. a.ed 60.3 yea.s(±9.7)were studied.74%of the popula.ion ha. a. lea.t one risk fa.tor a.d 51.6%of pa.ients ha. a.ta.ks in the la.t 6 *** wa. a.sta.istica.ly significa.t difference in the occurrence of m. a.ta.ks in the la.t 6 m.nths(p=0.014)between m. pa.ients with a.d without risk *** PTa.thresholds were higher a.d speech discrim.na.ion wa. lower in individua.s with m.re ca.diova.cula. risk ***:Trea.m.nt of m. focusing on va.cula. risk fa.tors m.0} a.low a.better control of sym.tom. a.d result in a.decrea.ed need for a.la.ive procedures in this disorder.

关键词： m.niere disea.e Ca.diova.cula. disea.e Hypertension Prognosis

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