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Cardiac output and cerebral perfusion after a stroke

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中华物理医学与康复杂志 2018年第4期 246-246页

作者： Fuhrer H reinhard m Niesen WD

BACKGROUND AND OBJECTIVE Restoring penumbral perfusion is the key therapeutic target in patients with acute ischemic *** cases of insufficient or unsuccessful vessel recanalization,maintaining normal to higher mean arterial pressure(mAP)is an accepted *** is expected to improve cerebral perfusion(CP),as constant cerebral blood flow(CBF)is maintained over a wide range of

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一种用于实时体绘制系统的自适应采样算法

电子学报 2002年第3期30卷 367-371页

作者：夏放怀沈振康唐朝京谌海新 Juergen Hesser Bernd Vettermann reinhard mnner 国防科技大学电子工程学院湖南长沙410073 Lehrstuhl für Informatik V

本文讨论了一种用于体绘制的、支持基于空间跳跃和自适应光线终止等优化算法的高效硬件结构及一种加速半透明物体绘制的新技术 .这种硬件结构用于绘制规模为 2 5 6 3 体元的数据时可达到 70Hz的帧频 ,但这样的帧频只是在体元的透明度都... 详细信息

本文讨论了一种用于体绘制的、支持基于空间跳跃和自适应光线终止等优化算法的高效硬件结构及一种加速半透明物体绘制的新技术 .这种硬件结构用于绘制规模为 2 5 6 3 体元的数据时可达到 70Hz的帧频 ,但这样的帧频只是在体元的透明度都被置为 0 (完全透明 )或 1(完全不透明 )的情况下才能取得 .引入新的加速技术后 ,绘制半透明物体的帧频也可接近上述数值 .新的加速技术采用自适应采样步长减少体绘制过程中冗余的体元重采样 ,从而使算法的复杂度和对存储器的带宽要求大大减小 .新的加速技术对半透明体数据可取得高达 4 7倍的加速比 .采用新的加速技术需要在开始交互绘制前对体数据进行距离编码 .优化后的距离编码对有 8兆体元的体数据的预处理时间仅需要 8～

关键词：算法距离编码实时体绘制系统自适应采样

安全生产的保障——第13次药品生产质量管理规范会议围绕药品的安全生产展开讨论

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流程工业 2008年第8期 14-15页

作者： reinhard Schnettler Ingrid müller Cornelia Wawretschek

除了讨论最为广泛的风险管理问题之外，第13次药品生产质量管理规范会议的另外一个中心设题围绕着医药产品原材料供应的问题展开。其他涉及到的讨论话题包括：高活性药物产品的生产、可靠供应商的资质以及关于活性药物成分的问题等等。

关键词：药品生产质量管理规范安全生产保障医药产品药物成分管理问题材料供应高活性

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预测颈内动脉狭窄患者卒中风险的新工具

临床荟萃 2014年第11期29卷 1301-1301页

作者： reinhard m Schwarzer G Briel m 本刊编辑部本刊编辑部

如果将所有患者均纳入考察范围的话，可以发现对无症状性颈内动脉（ICA）狭窄患者进行颈内动脉再通术使患者获益微小。因此，很重要的一点就是能够找出具有较高风险的一类患者，这样才能使颈内动脉再通术治疗成为最优选择。

关键词：颈内动脉狭窄高风险患者工具卒中预测无症状性再通术

Power Laws and Skew Distributions

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Communications in Computational Physics 2012年第8期12卷 721-731页

作者： reinhard mahnke Jevgenijs Kaupuzs mãrtins Brics Institute of Physics Rostock UniversityD-18051 RostockGermany Institute of mathematics and Computer Science University of LatviaLV-1459 RigaLatvia

Power-law distributions and other skew distributions,observed in various models and real systems,are considered.A model,describing evolving systems with increasing number of elements,is considered to study the distribution over element *** power-law distributions are *** non-stationary skew distributions are obtained and analyzed,based on exact solutions and numerical simulations.

关键词： Power law critical exponent evolving system skew distribution

Incidence of urinary incontinence following endoscopic laser enucleation of the prostate by en-bloc and non-en-bloc techniques:a multicenter,real-world experience of 5068 patients

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Asian Journal of Andrology 2024年第3期26卷 233-238页

作者： Daniele Castellani Vineet Gauhar Khi Yung Fong mario Sofer moisés Rodríguez Socarrás Azimdjon N Tursunkulov Lie Kwok Ying Sarvajit Biligere Ho Yee Tiong Dean Elterman Abhay mahajan mark Taratkin Sorokin Nikolai Ivanovich Tanuj Pal Bhatia Dmitry Enikeev Nariman Gadzhiev mohammed Taif Bendigeri Jeremy Yuen-Chun Teoh marco Dellabella Fernando Gómez Sancha Bhaskar Kumar Somani Thomas reinhard William Herrmann Urology Unit IRCCS INRCAAncona 60127Italy Urology Unit Marche University HospitalLe Marche Polytechnic UniversityAncona 60126Italy Department of Urology Ng Teng Fong General HospitalSingapore 609606Singapore Yong Loo Lin School of medicine National University of SingaporeSingapore 117597Singapore Department of Urology Tel Aviv Sourasky Medical CenterAffiliated to the Sackler School of MedicineTel Aviv UniversityTel Aviv 6423906Israel Department of Urology and Robotic Surgery ICUA-Clínica CEMTROMadrid 28701Spain Urology Division Akfa Medline HospitalTashkent 100211Uzbekistan Advanced Urology Gleneagles HospitalSingapore 258499Singapore Department of Urology National University HospitalSingapore 119228Singapore Divisionof Urology Department of SurgeryUniversity of TorontoOntarioToronto M5G 2C4Canada Department of Urology Mahatma Gandhi Mission’s Medical College and HospitalAurangabad 431003India Institute for Urology and Reproductive Health Sechenov UniversityMoscow119435Russian Federation Department of Urologyand Andrology Lomonosov Moscow State UniversityMoscow 119992Russian Federation Department of Urology Sarvodaya Hospital and Research CentreFaridabadHaryana 121006India Department of Urology Medical University of ViennaVienna 1090Austria Department of Urology Saint-Petersburg State University HospitalSaint-Petersburg 199034Russian Federation Department of Urology Asian Institute of Nephrology and UrologyHyderabad 500082India S.H.Ho UrologyCentre Department of SurgeryFaculty of MedicineThe Chinese University of Hong KongHong Kong 96H2+Q9China Department of Urology University Hospitals Southampton NHS TrustSouthampton SO166YDUnited Kingdom Department of Urology Cantonal Hospital Thurgau AGFraunfeld 8500Switzerland

We aim to evaluate the incidence of incontinence following laser endoscopic enucleation of the prostate(EEP)comparing en-bloc(Group 1)versus 2-lobe/3-lobe techniques(Group 2).We performed a retrospective review of patients undergoing EEP for benign prostaticenlargement in 12 centers between January 2020 and January *** were presented as median and interquartile range(IQR).Univariable and multivariable logistic regression analysis was performed to evaluate factors associated with stress urinary incontinence(SUI)and mixed urinary incontinence(mUI).There were 1711 patients in Group 1 and 3357 patients in Group *** in Group 2were significantly younger(68[62–73]years vs 69[63–74]years,P=0.002).median(interquartile range)prostate volume(PV)wassimilar between the groups(70[52–92]ml in Group 1 vs 70[54–90]ml in Group 2,P=0.774).There was no difference in preoperativeInternational Prostate Symptom Score,quality of life,or maximum flow ***,morcellation,and total surgical time weresignificantly shorter in Group *** 1 month,overall incontinence rate was 6.3%in Group 1 versus 5.3%in Group 2(P=0.12),and urge incontinence was significantly higher in Group 1(55.1%vs 37.3%in Group 2,Pmonths,the overall rate ofincontinence was 1.7%in Group 1 versus 2.3%in Group 2(P=0.06),and SUI was significantly higher in Group 2(55.6%vs 24.1%in Group 1,P=0.002).At multivariable analysis,PV and IPSS were factors significantly associated with higher odds of transient SUI/***,surgical time,and no early apical release technique were factors associated with higher odds of persistent SUI/mUI.

关键词： benign prostatic hyperplasia en-bloc enucleation endoscopic enucleation of the prostate laser therapy stress urinaryincontinence urge urinary incontinence

Hydrochemistry, Origin and Evolution of Sedimentary Subsurface Fluids:——Ⅱ. Early diagenetic pore-water evolution in high sedimentation-rate offshore basins

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Acta Geochimica 1987年第1期6卷 1-18页

作者： reinhard HESSE Department of Geological Sciences mcGill University montreal Quebec H3A 2A7 Canada

High sedimentation-rate basins are characteristic of the continental margins, where sedimentation ratesup to 500m/ma and more are no exception. The sediments are rich in organic matter and undergo awell-established sequence of bacterial oxidation reactions, starting at the sediment/water interface with:（1）the oxidation zone （absent in euxinic basins）, which is followed downwards by （2） the nitrate reduction zone,（3） the sulfate reduction zone, （4） the carbonate reduction zone, （5） the fermentation zone and （6） thedecarboxylation zone, which marks the onset of thermocatalytic reactions characteristic of the intermediatestage （and deeper stages） of diagenesis. This sequence of bacterially mediated organic-matter decomposition reactions in rapidly depositedsediments on the continental margins is well reflected in the vertical trends of pore-water chemistry. Carbonisotopic fractionation permits to distinguish between zones （1） to （3） with negative δ;C values for the CO;generated, and between zones （4） and （5） with increasingly heavier carbon-isotopes in CO;(up to + 15 to+ 25‰δ;C). The formation of gas-hydrates causes characteristic chemical and isotopic signatures in porewaters retrieved from hydrate-beating sediments. After hydrate decomposition （in the sampling process orat the base of hydrate zones） marked chlorimity decreases accompanied by increases in heavy oxygenisotopes are observed. These are distinctly different from the effects of meteoric water influx, which are notaccompanied by positive δ;O values. The opposite trend of increasing salinity at shallow burial depths,rather than pore-waters freshening, is observed in the vicinity of evaporites.

关键词： Origin and Evolution of Sedimentary Subsurface Fluids Early diagenetic pore-water evolution in high sedimentation-rate offshore basins Hydrochemistry rate high

Root Exudation of Organic Acids of Herbaceous Pioneer Plants and Their Growth in Sterile and Non-Sterile Nutrient-Poor,Sandy Soils from Post-mining Sites

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Pedosphere 2019年第1期29卷 34-44页

作者： Katja BOLDT-BURISCH Bernd Uwe SCHNEIDER m.Anne NAETH reinhard F.HTTL Chair of Soil Protection and Recultivation Brandenburg University of Technology Helmholtz Centre Potsdam-German Research Centre for Geosciences Department of Renewable Resources University of Alberta

Nutrient-poor, sandy soils form the prevailing substrate at post-mining sites of the Lusatian region(Brandenburg, Germany) and present a challenge for vegetation development. We studied the organic acid quantity and composition of three commonly occurring pioneer plant species, the legumes Lotus corniculatus L. and Trifolium arvense L. and the grass Calamagrostis epigeios(L.) Roth, to determine if plant growth and exudation differed with(non-sterilized soil) and without(sterilized soil) an indigenous soil microbial community. We investigated whether organic acids were found in the rhizosphere and surrounding soil and whether this influenced nutrient mobilization. This study consists of linked field investigations and a greenhouse experiment. Plants were grown in the greenhouse in either sterilized or non-sterilized sandy soil from a reclamation site in the Lusatian mining landscape(Welzow Su¨d, East Germany). After seven months, the plant biomass, root morphology, organic acids, and water-soluble nutrients and root colonization with arbuscular mycorrhizal fungi(AmF) and dark septate endophytes(DSE) were analyzed. Roots of all three plants in the field and greenhouse experiments were highly colonized with AmF. Calamagrostis epigeios and T. arvense had a significantly higher colonization frequency with DSE than L. corniculatus. The quantity and composition of organic acids strongly differed among plant species, with the highest number of organic acids found for L. corniculatus and lowest for C. epigeios. The quantity of organic acids was greatly reduced in all plants under sterilized soil conditions. However, the composition of organic acids and plant growth in sterilized soil were reduced for both legumes, but not for C. epigeios, which had a higher biomass under sterilized conditions. Changes in nutrient concentrations in the field rhizosphere soil relative to those in the control were measurable after seven months. While the spectrum of organic acids and the growth

关键词： Calamagrostis epigeios indigenous soil microbial community Lotus corniculatus microbial colonization mining landscape nutrient mobilization root symbiotic partner Trifolium arvense

Chronic Hyperinsulinism Induced Down-regulation of Insulin Post-Receptor Signaling Transduction in Hep G2 Cells

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Journal of Huazhong University of Science and Technology(medical Sciences) 2002年第4期22卷 313-316页

作者：袁莉 reinhard Ziegler Andreas Hamann DepartmentofEndocrinologyandmetabolism

To study the regulatory effect of acute and chronic insulin treatmenton insulin post- re- ceptor signaling transduction pathway in a human hepatom a cell line (Hep G2 ) ,Hep G2 cells were incubated in the presence or absence of insulin with different concentrations in serum free m edia for16 h and then stim ulated with10 0 nmol/ L insulin for1m *** levels of insulin receptor β- subunit(IRβ) ,insulin receptor substrate- 1(IRS- 1) and p85 subunit of phosphatidylinositol3- kinase(PI3- kinase) were determined in total cell lysates by Western- im ***- ed proteins IRβ,IRS- 1and interaction of PI3- kinase with IRS- 1were determ ined by im munopre- *** showed that 1- min insulin stimulation rapidly induced tyrosine phosphorylation of IRβ and IRS- 1,which in turn,resulting in association of PI 3- kinase with IRS- 1.1- 10 0 nm ol/ L chronic insulin treatment induced a dose- dependent decrease in the protein level of IRβ and a slight decrease in the protein level of IRS- *** was a m ore marked reduction in the phospho- rylation of IRβ,IRS- 1,reaching a nadir of2 2 % (Pment with 10 0 nm ol/ L *** association between IRS- 1 and PI3- kinase was decreased by6 6 % (Pm ent can induce alterations of IRβ,IRS- 1and PI 3- kinase three early steps in insulin action,which contributes significantly to insulin resistance,and may account for desensitization of insulin action.

关键词： insulin insulin signaling transduction insulin resistance