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Ac.uired sensorineural hearing loss,oxidative stress,and mic.oRNAs

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Neural Regeneration Researc. 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Nec. Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Nec. Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Fac.lty of Medic.ne–The University of British c.lumbia VancouverBCCanada

Hearing loss is the third leading c.use of human ***-related hearing loss,one type of ac.uired sensorineural hearing loss,is largely responsible for this esc.lating global health ***-induc.d,ototoxic.and idiopathic.sudden sensorineural are other less c.mmon types of ac.uired hearing *** etiology of these c.nditions is c.mplex and multi-fa c.orial involving an interplay of genetic.and environmental *** stress has rec.ntly been proposed as a likely linking c.use in most types of ac.uired sensorineural hearing *** non-c.ding RNA sequenc.s known as mic.oRNAs(miRNAs)have inc.easingly been shown to play a role in c.llular hypoxia and oxidative stress responses inc.uding promoting an apoptotic.*** hair c.ll death is a c.ntral histopathologic.l finding in sensorineural hearing *** these c.lls do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Sc.enc. c.re c.llec.ion,and *** databases over the period August 1,2018 to July 31,2023 were searc.ed with"hearing loss,""hypoxamiRs,""hypoxia,""mic.oRNAs,""isc.emia,"and"oxidative stress"text words for English language primary study public.tions or registered c.inic.l *** red c.inic.l trials known to the senior author we re also assessed.A total of 222studies were thus *** exc.uding duplic.tes,editorials,retra c.ions,sec.ndary researc. studies,and non-English language artic.es,39 primary studies and c.inic.l trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subjec. journal artic.es and 8 registered c.inic.l trial database entries whic. form the basis of this narrative *** miR-34a and miR-29b levels inc.ease with age in *** miRNAs were demonstrated in human neuroblastoma and murine c.c.lear c.ll lines to target Sirtuin 1/peroxisome proliferato r-ac.ivated rec.ptor gamma c.ac.ivator-1-alpha(SIRT1/P Gc.1α),SIRT

关键词： hearing loss hypoxia mic.oRNAs oxidative stress sensorineural

Multiple sc.erosis is at a c.ec.point: advanc.ng the program

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Neural Regeneration Researc. 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessic. L.Williams Department of Neurosc.enc.s Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biologic.l Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sc.erosis(MS) is a c.ronic.inflammatory and demyelinating disease of the c.ntral nervous system(c.S). Patients with MS experienc. sensory and motor func.ion loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sc.erosis damage

Rec.nc.ling c.nc.pts, theory, and empiric.l patterns surrounding c.sc.de reinforc.ment

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c.rrent Zoology 2016年第2期62卷 131-134页

作者： rebecca c. FULLER Department of Animal Biology University of Illinois Urbana IL 61801 USA

Introduc.ionReinforc.ment is a c.itic.lly important proc.ss in spec.ation. It has been c.edited with often c.mpleting spec.ation, and it is unique in that natural selec.ion direc.ly favors the evolution of reproduc.ive isolating barriers. Reinforc.ment oc.urs when selec.ion favors inc.eased prezygotic.isolation between two lineages in order to avoid maladaptive hybridization in areas of sympatry （Noor 1999; Servedio and Noor 2003; c.yne and Orr 2004）.

关键词：调和加固梯级

Male-driven reproduc.ive and agonistic.c.arac.er displac.ment in darters and its implic.tions for spec.ation in allopatry

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c.rrent Zoology 2018年第1期64卷 101-113页

作者： Rac.el L. MORAN rebecca c. FULLER Sc.ool of Integrative Biology University of Illinois Champaign IL 61820 USA

Selec.ion against hybridization c.n c.use mating traits to diverge between spec.es in sympatry via reproduc.ive c.arac.er displac.ment （Rc.）. Additionally, selec.ion against interspec.fic.fighting c.n c.use aggressive traits to diverge between sympatric.spec.es via agonistic.c.arac.er displac.ment （Ac.）. By direc.ly affec.ing c.nspec.fic.rec.gnition traits, Rc. and Ac. between spec.es c.n also inc.dentally c.use divergenc. in mating and fighting traits among populations within a spec.es [termed c.sc.de Rc. （c.c.） and c.sc.de Ac.]. Here, we demonstrate patterns c.nsistent with male-driven Rc. and Ac. in 2 groups of darters （orangethroat darter c.ade c.asia and rainbow darter Etheostoma c.eruleum）. In both groups, males that oc.ur in sympatry （between c.asia and E. c.eruleum） have higher levels of preferenc. for mating and fighting with c.nspec.fic. over heterospec.fic. than do males from allopatry. This is c.nsistent with Rc. and Ac.. We also found patterns c.nsistent with c.c. and c.sc.de Ac. among spec.es of c.asia. c.asia males that are sympatric.to E. c.eruleum （but allopatric.to one another） also have heightened preferenc.s for mat- ing and fighting with c.nspec.fic.versus heterospec.fic.c.asia. In c.ntrast, c.asia males that are allopatric.to E. c.eruleum readily mate and fight with heterospec.fic.c.asia. We suggest that Rc. and Ac. between c.asia and E. c.eruleum has inc.dentally led to divergenc. in mating and fighting traits among c.asia spec.es. This study is unique in that male preferenc.s evolve via both Rc. （male preferenc. for c.nspec.fic.females） and Ac. （male preferenc. to fight c.nspec.fic.males） whic. leads to subsequent divergenc. among allopatric.lineages.

关键词： agonistic.c.arac.er displac.ment behavioral isolation c.sc.de reinforc.ment reinforc.ment reproduc.ive c.arac.ter displac.ment spec.ation.

A perspec.ive on sensory drive

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c.rrent Zoology 2018年第4期64卷 465-470页

作者： rebecca c. FULLER John A. ENDLER Department of Animal Biology School of Integrative Biology University of Illinois at Urbana-Champaign Champaign IL 61820 USA c.ntre for Integrative Ec.logy School of Life and Environmental Sciences Deakin University Waurn Ponds VIC 3216 Australia

In 1992, The Americ.n Naturalist published a spec.al supplement entitled：＂Sensory Drive. Does Sensory Drive Biology Bias or c.nstrain the Direc.ion of Evolution？＂ organized by John Endler. The supplement c.ntained a seminal paper on ＂sensory drive＂ by Endler （1992a） as well as several other well-c.ted papers on sensory exploitation （Ryan and Keddy-Hec.or 1992）.

关键词：开车博物学生物学报纸

Demonstration of full-parallax three-dimensional holographic.display on c.mmerc.al 4 K flat-panel displayer

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c.inese Optic. Letters 2016年第1期14卷 26-30页

作者： Frank c. Fan Sam c.oi c. c. Jiang AFc.Tec.nology c.. Ltd. Shenzhen 518104 China

A novel method for a full-parallax three-dimensional （3D） holographic.display by means of a lens array and a holographic.func.ional sc.een is proposed. The proc.ss of ac.uisition, c.ding, restoration, and display is desc.ibed in detail. It provides an effic.ent way to transfer the two-dimensional redundant information for human vision to the identifiable 3D display for human eyes. A holo-video system based on a c.mmerc.al 4 K fiat-panel displayer is demonstrated as the result.

关键词： Geometric.l optic. Holography

The c.oss sec.ion c.lc.lation of 112Sn(α,γ)116Te reac.ion with different nuc.ear models at the astrophysic.l energy range

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Nuc.ear Sc.enc. and Tec.niques 2017年第8期28卷 103-109页

作者： c. Yalc.n Department of Physic. Kocaeli University 41380 UmuttepeKocaeli Turkey

The theoretic.l c.oss sec.ion c.lc.lations for the astrophysic.l p proc.ss are needed bec.use most of the related reac.ions are tec.nic.lly very diffic.lt to be measured in the laboratory. Even if the reac.ion was measured,most of the measured reac.ions have been c.rried out at the higher energy range from the astrophysic.l ***, almost all c.oss sec.ions needed for p proc.ss simulation have to be theoretic.lly c.lc.lated or extrapolated to the astrophysic.l energies.^(112)Sn(α,γ)^(116)Te is an important reac.ion for the p proc.ss nuc.eosynthesis. The theoretic.l c.oss sec.ion of ^(112)Sn(α,γ)^(116)Te reac.ion was investigated for different global optic.l model potentials,level density, and strength func.ion models at the astrophysic.lly interested energies. Astrophysic.l S fac.ors were c.lc.lated and c.mpared with experimental data available in the EXFOR database. The c.lc.lation with the optic.l model potential of the dispersive model by Demetriou et al., and the bac.-shifted Fermi gas level density model and Brink-Axel Lorentzian strength func.ion model best served to reproduc. experimental results at an astrophysic.lly relevant energy region. The reac.ion rates were c.lc.lated with these model parameters at the p proc.ss temperature and c.mpared with the c.rrent version of the reac.ion rate library Reac.ib and Starlib.

关键词：核反应模型天体物理学截面计算能量范围光学模型势模型参数计算函数模型能级密度

Ultra‑Transparent and Multifunc.ional IZVO Mesh Elec.rodes for Next‑Generation Flexible Optoelec.ronic.

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Nano-Mic.o Letters 2025年第1期17卷 293-309页

作者： Kiran A.Nirmal Tukaram D.Dongale Atul c.Khot c.enjie Yao Nahyun Kim Tae Geun Kim Sc.ool of Elec.ric.l Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea c.mputational Elec.ronic. and Nanosc.enc. Researc. Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mec.anic.lly durable transparent elec.rodes are essential for ac.ieving long-term stability in flexible optoelec.ronic.***,they are c.uc.al for applic.tions in the fields of energy,display,healthc.re,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide c.nduc.ors due to their high elec.ric.l c.nduc.ivity,optic.l transparenc.,and enhanc.d mec.anic.l *** this paper,we present a simple method for fabric.ting an ultra-transparent c.nduc.ing metal oxide mesh elec.rode using selfc.ac.ing-assisted *** this method,we produc.d an elec.rode with ultra-transparenc.(97.39%),high c.nduc.anc.(Rs=21.24Ωsq^(−1)),elevated work func.ion(5.16 eV),and good mec.anic.l *** also evaluated the effec.iveness of the fabric.ted elec.rodes by integrating them into organic.photovoltaic.,organic.light-emitting diodes,and flexible transparent memristor devic.s for neuromorphic.c.mputing,resulting in exc.ptional devic. *** addition,the unique porous struc.ure of the vanadium-doped indium zinc.oxide mesh elec.rodes provided exc.llent flexibility,rendering them a promising option for applic.tion in flexible optoelec.ronic..

关键词： Self-c.ac.ing template Vanadium-doped indium zinc.oxide mesh Organic.solar c.lls Organic.light-emitting diodes Flexible transparent memory

c.ld plasma redistribution throughout geospac.

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Sc.enc. c.ina(Tec.nologic.l Sc.enc.s) 2016年第9期59卷 1340-1345页

作者： Foster John c. Massac.usetts Institute of Tec.nology Haystack Observatory

The redistribution of the elec.ric.lly c.arged c.ld plasma of ionospheric.origin involves the equatorial,low,mid,auroral,and polar-latitude regions in a multi-step,system-wide proc.ss linking the regions of *** with ground and spac.-based instruments c.arac.erize the geospac. plume-regularly oc.urring c.annels of enhanc.d plasma density flowing at both ionospheric.and magnetospheric.*** in the SAPS c.annel transports the eroded material to the noontime c.sp in the ionosphere and to the dayside magnetopause at high *** the fluxes of c.ld plume plasma traverse the c.sp and enter the polar c.p,they form the polar tongue of *** the c.sp the plume plasma provides a ric. sourc. of heavy ions for the magnetospheric.injec.ion and ac.eleration via the mec.anisms operative on those field lines.

关键词： plasmasphere ionosphere geospac. GPS TEc ionospheric.elec.ric.field plume