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肝脏影像报告和数据系统局部治疗反应标准的诊断准确性：系统回顾和荟萃分析

自动化学报（英文版） 2021年第12期

作者： Mamta Brij B.gupta kuan-Ching Li Victor C. M. Leun kostas E.Psannis Shingo Yamaguchi

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国际医学放射学杂志 2021年第6期 747-747页

作者： P.gupta A.Bansal G.C.Das P.kumar-M S.B.Chaluvashetty H.Bhujade 郭虹

目的肝脏成像报告和数据系统(LI-RADS)治疗反应(LR-TR)采用的标准日益增加。然而,仍相对缺乏评估这些标准效能的证据。本研究目的是评估LI-RADS LR-TR

关键词：

新近诊断的乳腺癌:对比增强能谱乳腺X线摄影与乳腺MRI评价病变范围的比较

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国际医学放射学杂志 2018年第1期 90-90页

作者： S.A.Lee-Felker L.Tekchandani M.Thomas E.gupta D.AndrewsTang A.Roth 张俊峰 Department of Radiological Sciences David Geffen School of Medicine at UCLA

摘要目的以病理和影像随访作为参考标准,比较对比增强能谱乳腺摄影与乳腺MRI对新近诊断乳腺癌病人额外病灶检出的诊断价值。材料与方法本研究经机构伦理委员

关键词：对比增强 MRI 病变范围乳腺癌

Measurements of dihadron correlations relative to the event plane in Au+Au collisions at√^(S)NN=200 GeV

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Chinese Physics C 2021年第4期45卷 198-241页

作者： H.Agakishiev M.M.Aggarwal Z.Ahammed A.V.Alakhverdyants I.Alekseev J.Alford B.D.Anderson C.D.Anson D.Arkhipkin G.S.Averichev J.Balewski D.R.Beavis N.k.Behera R.Bellwied M.J.Betancourt R.R.Betts A.Bhasin A.k.Bhat H.Bichsel J.Bieleik J.Bielcikova B.Biritz L.C.Bland W.Borowski J.Bouchet E.Braidot A.V.Brandin A.Bridgeman S.G.Brovko E.Bruna S.Bueltmann I.Bunzarov T.P.Burton X.Z.Cai H.Caines M.Calderon de la Barca Sanchez D.Cebra R.Cendejas M.C.Cervantes Z.Chajecki P.Chaloupka S.Chattopadhyay H.F.Chen J.H.Chen J.Y.Chen L.Chen J.Cheng M.Cherney A.Chikanian k.E.Choi W.Christie P.Chung M.J.M.Codrington R.Corliss J.G.Cramer H.J.Crawford S.Dash A.Davila Leyva L.C.De Silvat R.R.Debbe T.G.Dedovich A.A.Derevschikov R.Derradi de Souza L.Didenko P.Djawotho S.M.Dogra X.Dong J.L.Drachenberg J.E.Draper J.C.Dunlop L.G Efimov M.Elnim J.Engelage G Eppley M.Estienne L.Eun O.Evdokimov R.Fatemi J.Fedorisin A.Feng R.G.Fersch P.Filip E.Finch V.Fine Y.Fisyak C.A.Gagliardi D.R.Gangadharan A.Geromitsos F.Geurts P.Ghosh Y.N.Gorbunov A.Gordon O.Grebenyuk D.Grosnick S.M.Guertin A.gupta W.Guryn B.Haag O.Hajkova A.Hamed L-X.Han J.W.Harris J.P.Hays-Wehle M.Heinz S.Heppelmann A.Hirsch E.Hjort G.W.Hoffmann D.J.Hofiman B.Huang H.Z.Huang T.J.Humanic L.Huo G.Igo P.Jacobs W.W.Jacobs C.Jena F.Jin J.Joseph E.G.Judd S.kabana k.kang J.kapitan k.kauder H.ke D.keane A.kechechyan D.kettler D.P.kikola J.kiryluk A.kisiel V.kizka A.G.knospe D.D.koetke T.kollegger J.konzer I.koralt L.koroleva W.korsch L.kotchenda V.kouchpil P.kravtsov k.krueger M.krus L.kumar P.kurnadi M.A.C.Lamont J.M.Landgraf S.LaPointe J.Lauret A.Lebedev R.Lednicky J.H.Lee W.Leight M.J.LeVine C.Lil L.Li N.Li W.Li X.Li X.Li Y.Li Z.M.Li M.A.Lisa F.Liu H.Liu J.Liu T.Ljubicic W.J.Llope R.S.Longacre W.A.Love Y.Lu E.V.Lukashov X.Luo G.L.Ma Y.G.Mai D.P.Mahapatra R.Majka O.I.Mall L.k.Mangotra R.Manweiler S.Margetis C.Markert H.Masui H.S.Matis Yu.A.Matulenko D.MeDonald T.S.McShane A.Meschanin R.Milner N.G.Minaev S.Mioduszewski A.Mischke M.k.Mitrovski B.Mohanty M.M.Mondal B.Morozov D.A.Morozov M.G.Munhoz M Argonne National Laboratory Argonnellinois 60439USA Brookhaven National Laboratory UptonNew York 11973USA University of Califomia BerkeleyCaliformnia 94720USA University of California DavisCalifornia 95616USA University of Califormnia Los AngelesCalifomia 90095USA Universidade Estadual de Campinas Sao PauloBrazil University of Illinois at Chicago ChicagoIlinois 60607USA Creighton University OmahaNebraska 68178USA Czech Technical University in Prague FNSPEPrague11519Czech Republic Nuclear Physics Institute AS CR 25068 Rez/PragueCzech Republic University of Frankfurt FrankfurtGermany Institute of Physics Bhubaneswar 751005India Indian Institute of Technology MumbaiIndia Indiana University BloomingtonIndiana 47408USA Alikhanov Instiute for Theoretical and Experimental Physics MoscowRussia University of Jammu Jammu 180001India Joint Institute for Nuclear Research Dubna141980Russia kent State University KentOhio 44242USA University of kentucky LexingtonKentucky40506-0055USA Institute of Modern Physics LanzhouChina Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720USA Massachusetts Institute of Technology CambridgeMA 02139-4307USA Mx-Planck-Institut fir Physik MunichGermany Michigan State University East LansingMichigan 48824USA Moscow Engineering Physics Institute Moscow Russia NIkHEF and Utrecht University AmsterdamThe Netherlands Ohio State University ColumbusOhio 43210USA Old Dominion University NorfolkVA23529USA Panjab University Chandigarh 160014India PennsyIvania State University University ParkPennsylvania 16802USA Institute of High Energy Physics ProtvinoRussia Purdue University West LafayetteIndiana 47907USA Pusan National University PusanRepublic of Korea University of Rajasthan Jaipur 302004India Rice University HoustonTexas 77251USA Universidade de Sao Paulo Sao PauloBrazil University of Science&Technology of China Hefei 230026.China Shandong University JinanShandong 250100China Shanghai Institute of Applied Physics Shanghai 201800Chi

Dihadron azimuthal correlations containing a high transverse momentum(pr)trigger particle are sensit-ive to the properties of the nuclear medium created at RHIC through the strong interactions occurring between the traversing parton and the medium,*** measurements revealed a strong modification to di-hadron azimuthal correlations in Au+Au collisions with respect to ptp and d+Au *** modification in-creases with the collision centrality,suggesting a path-length or energy density dependence to the je-quenching *** paper reports STAR measurements of dihadron azimuthal correlations in mid-central(20%-60%)Au+Au collisions at√^(S)NN=200 GeV as a function of the trigger particle's azimuthal angle relative to the event plane,Ф_(s)=|Ф_(t)-ψ_(Ep)|.The azimuthal correlation is studied as a function of both the trigger and associated particle *** subtractions of the combinatorial background and anisotropic flow,assuming Zero Yield At Minimum(ZYAM),are *** correlation results are first discussed with subtraction of the even harmonic(elliptic and quadrangu-lar)flow *** away-side correlation is strongly modifed,and the modification varies withФ_(s),with a double-peak structure for out-of-plane trigger *** near-side ridge(long range pseudo-rapidity△_(η)correla-tion)appears to drop with increasingФ_(s)while the jet-like component remains approximately *** correla-tion functions are further studied with the subtraction of odd harmonic triangular flow background arising from *** is found that the triangular flow,while responsible for the majority of the amplitudes,is not sufficient to explain theφs-dependence of the ridge or the away-side double-peak *** dropping ridge withФ_(s)could be attributed to aФ_(s)-dependent lliptie anisotropy;however,the physics mechanism of the ridge remains an open *** with aФ_(s)-dependent elliptic flow,the away-side correlation structure

关键词： relativistic heavy ion collisions dihadron correlations jet-medium interactions anisotropic flow background event plane

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如何兼得客户满意度与盈利（上）

新营销 2014年第9期 82-84页

作者： Timothy keiningham Alexander Buoye Sunil gupta Lerzan Aksoy 益普索Loyalty 哈佛大学工商管理系福特汉姆大学市场营销系

管理者通常认为,提升客户满意度与提高收益密切相关,然而事实却没有那么简单。1875年,美国蒙哥马利?沃德百货公司首次提出"包您满意,不满意就退款"的口号,试图使其自己的邮购目录业务在与其他零售商的竞争中脱颖而出。此后,这一承诺开... 详细信息

管理者通常认为,提升客户满意度与提高收益密切相关,然而事实却没有那么简单。1875年,美国蒙哥马利?沃德百货公司首次提出"包您满意,不满意就退款"的口号,试图使其自己的邮购目录业务在与其他零售商的竞争中脱颖而出。此后,这一承诺开始被使用。如今让客户满意

关键词：客户忠诚度沃德蒙哥马利 ACSI 反比关系满意度水平营销计划银行客户满意度指数银行账户

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如何兼得客户满意度与盈利（下）

Texture analysis on parametric maps derived from dynamic contrast-enhanced magnetic resonance imaging in head and neck cancer

新营销 2014年第10期 90-92页

作者： Timothy keiningham Alexander Buoye Sunil gupta Lerzan Aksoy 益普索哈佛大学工商管理系福特汉姆大学市场营销系

管理者通常认为,提升客户满意度与提高收益密切相关,然而事实却没有那么简单。让满意度为你带来好处上述发现表明,客户满意度与公司盈利关系微弱,但事情并非一定如此。下面几个操作简单的策略,可以保证二者兼得。

关键词：客户忠诚度意度市场占有率市场占比利润流满意度水平高忠诚度差异化战略商业战略交叉销售

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World Journal of Radiology 2016年第1期8卷 90-97页

作者： Jacobus FA Jansen Yonggang Lu Gaorav gupta Nancy Y Lee Hilda E Stambuk Yousef Mazaheri Joseph O Deasy Amita Shukla-Dave Department of Radiology Maastricht University Medical Center Department of Medical Physics Memorial SloanKettering Cancer Center Departments of Radiation Oncology Memorial Sloan-Kettering Cancer Center Department of Radiology Memorial Sloan-Kettering Cancer Center

AIM: To investigate the merits of texture analysis on parametric maps derived from pharmacokinetic modeling with dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) as imaging biomarkers for the prediction of treatment response in patients with head and neck squamous cell carcinoma(HNSCC). METHODS: In this retrospective study,19 HNSCC patients underwent pre- and intra-treatment DCEMRI scans at a 1.5T MRI scanner. All patients had chemo-radiation treatment. Pharmacokinetic modeling was performed on the acquired DCE-MRI images,generating maps of volume transfer rate(ktrans) and volume fraction of the extravascular extracellular space(ve). Image texture analysis was then employed on maps of ktrans and ve,generating two texture measures: Energy(E) and ***: No significant changes were found for the mean and standard deviation for ktrans and ve between pre- and intra-treatment(P > 0.09). Texture analysis revealed that the imaging biomarker E of ve was significantly higher in intra-treatment scans,relative to pretreatment scans(P < 0.04). CONCLUSION: Chemo-radiation treatment in HNSCC significantly reduces the heterogeneity of tumors.

关键词： Tumor heterogeneity Dynamic contrastenhanced magnetic resonance imaging Image texture analysis Head and neck squamous cell carcinomas

利伐沙斑对非瓣膜性房颤和肿瘤患者继发卒中的预防作用

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国际老年医学杂志 2017年第5期38卷 F0003-F0003页

作者： Laube ES Yu A gupta D 袁志敏

本文研究的目的是探讨利伐沙斑（Rivaroxaban）治疗非瓣膜性房颤（At）和肿瘤患者的疗效和安全性。

关键词：非瓣膜性房颤肿瘤患者预防作用卒中继发安全性

帕博利珠单抗治疗伴脑转移NSCLC患者的一项非随机、开放Ⅱ期试验的长期随访结果和生物标志物分析

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中国肺癌杂志 2021年第9期24卷 I0007-I0016页

作者： Sarah B GOLDBERG kurt A SCHALPER Scott N GETTINGER Amit MAHAJAN Roy S HERBST Anne C CHANG Rogerio LILENBAUM Frederick H WILSON Sacit Bulent OMAY James B YU Lucia JILAVEANU Thuy TRAN kira PAVLIk Elin ROWEN Heather GERRSH Annette kOMLO Richa gupta Hailey WYATT Matthew RIBEIRO Yuval kLUGER Geyu ZHOU Wei WEI Veronica L CHANG Harriet M kLUGER 董晓荣(翻译/校对) Department of Medicine(Medical Oncology) Yale School of MedicineNew HavenCTUSA Department of Pathology Yale School of MedicineNew HavenCTUSA Department of Radiology Yale School of MedicineNew HavenCTUSA Department of Neurosurgery Yale School of MedicineNew HavenCTUSA Department of Therapeutic Radiology Yale School of MedicineNew HavenCTUSA Interdepartmental Program in Computational Biology and Bioinformatics Yale School of MedicineNew HavenCTUSA Department of Biostatistics Yale School of Public HealthNew HavenCTUSA 华中科技大学同济医学院附属协和医院胸部肿瘤科

背景与目的我们开展了一项帕博利珠单抗用于伴未治疗脑转移的非小细胞肺癌(non-small cell lung cancer,NSCLC)或黑色素瘤患者的疗效和安全性的II期试验,旨在评估程序性死亡受体1(programmed cell death 1,PD-1)抑制剂在中枢神经系统(ce... 详细信息

背景与目的我们开展了一项帕博利珠单抗用于伴未治疗脑转移的非小细胞肺癌(non-small cell lung cancer,NSCLC)或黑色素瘤患者的疗效和安全性的II期试验,旨在评估程序性死亡受体1(programmed cell death 1,PD-1)抑制剂在中枢神经系统(central nervous system,CNS)中的疗效。中期结果已发表,现报道对NSCLC队列的更新分析结果。方法这是一项开放性、单中心、II期试验。纳入标准:年龄≥18岁,诊断为晚期NSCLC并伴有≥1个5 mm-20 mm脑转移病灶,既往从未治疗或之前放疗后进展,无神经系统症状,不需要激素治疗且美国东部肿瘤协作组(Eastern Cooperative Oncology Group,ECOG)kg)治疗。队列1为程序性死亡配体1(programmed cell death ligand 1,PD-L1)≥1%的患者,队列2为PD-L1<1%或未评估的患者。主要终点是脑转移患者缓解比例。所有经治患者均纳入疗效与安全性终点的分析。该研究已结束入组,并于***登记注册,注册号为NCT02085070。结果2014年3月31日-2018年5月21日,共42例患者接受治疗。中位随访时间为8.3个月(IQR:4.5个月-26.2个月)。队列1的37例患者中11例有脑转移缓解[29.7%(95%CI:15.9%-47.0%)]。队列2未观察到缓解。治疗相关的3级-4级不良事件(adverse events,AEs)包括2例肺炎、1例全身症状、1例结肠炎、1例肾上腺皮质功能不全、1例高血糖症和1例低钾血症。6例(14%)患者发生了治疗相关的严重不良事件,包括肺炎、急性肾损伤、低钾血症和肾上腺皮质功能不全。没有观察到治疗相关死亡病例。结论帕博利珠单抗治疗PD-L1≥1%的NSCLC伴脑转移患者有效,且对所有纳入的未经治疗的脑转移患者安全。需要进一步探索免疫治疗用于NSCLC合并CNS转移。

关键词：非小细胞肺癌脑转移免疫治疗帕博利珠单抗

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剪切波弹性成像与传统超声及MRI对骨肌系统软组织良恶性肿瘤鉴别诊断能力的比较

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国际医学放射学杂志 2019年第2期42卷 238-238页

作者： A.N.Tavare A.M.Alfuraih E.M.A.Hensor E.Astrinakis H.gupta P.Robinson 田禹(译) 刘晨(校) Musculoskeletal Centre X-Ray Department Leeds Teaching Hospitals TrustChapel Allerton HospitalLeeds LS7 4SAEngland 不详

目的探讨剪切波弹性成像(SWE)与单一超声检查或超声联合MRI检查相比,能否提高软组织肿块良恶性诊断的准确性。材料与方法2015年12月—2017年3月间连续招募预行软组织肿块活检的206例成年病人(年龄18~91岁,平均57.7岁),其中男89例(年龄21... 详细信息

目的探讨剪切波弹性成像(SWE)与单一超声检查或超声联合MRI检查相比,能否提高软组织肿块良恶性诊断的准确性。材料与方法2015年12月—2017年3月间连续招募预行软组织肿块活检的206例成年病人(年龄18~91岁,平均57.7岁),其中男89例(年龄21~91岁,平均56.0岁),女117例(年龄18~88岁,平均59.1岁),活检前病人接受了B超、MRI和SWE检查。

关键词：剪切波弹性成像良恶性 MRI

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