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Ocuton S眼压计自测法:青光眼患者的眼压测量准确性评价

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世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 6-6页

作者： Sacu S. Vass C. Schemper M. rainer G. 杨建刚 Medical University Vienna Department of Ophthalmology Waehringer Guertel 18-20 A-1090 Vienna Austria Dr.

Background: To compare two methods of measuring intraocular pressure (IOP) and to evaluate whether repeated measurements taken with the Ocuton S applanation s elf-tonometer can improve reliability. Methods: Ocuton S and Goldmann applanati on tonometry (GAT), and corneal thickness measurements taken with the Orbscan to pography system, were successfully performed in 64 of 68 glaucoma patients. Resu lts: The median IOPs were 15.5mmHg using GAT, and 16 mmHg using the first self- taken Ocuton S measurement (n=64). The differences between the median of the GAT measurements and the first Ocuton S measurement, and the medians of the three a nd six separate Ocuton S measurements were within 3 mmHg in 52%, 59%and 67%of cases, respectively. The mean corneal thickness of all evaluated eyes was 545.3 μm. There was no effect of corneal thickness on the accuracy of either of the two devices (P > 0.05). Conclusion: Repeated measurements can improve the reliab ility of the Ocuton S. However, ever with repeated measurements only every secon d patient succeeds in obtaining reliable measurements.

关键词：眼压测量 Ocuton S 角膜厚度角膜地形图重复测量仪器检查

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沉重的时刻

德语学习 2010年第5期 1-1页

作者：里尔克冯至

此刻有谁在世上的某处哭，无缘无故地在世上哭，哭我。

关键词：《沉重的时刻》德语

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总是一再地

德语学习 2011年第5期 1-1页

作者：里尔克冯至

总是一再地，虽然我们认识爱的风景，认识教堂小墓场前刻着它哀悼的名姓。

关键词：德语学习学习方法阅读知识《总是一再地》

弥散加权成像示多发性急性大脑梗死与卒中复发的风险

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世界核心医学期刊文摘（神经病学分册） 2005年第3期1卷 59-59页

作者： Wen H.M. Lam W.W.M. rainer T. K.S. Wong 高方 Dept. of Medicine and Therapeutics Prince of Wales Hospital S hatin Hong Kong Dr.

Multiple acute cerebral infarcts (MACIs) detected by diffu sion weighted ima ging (DWI) may indicate an unstable source of thromboembolism. The authors studi ed 119 consecutive acute ischemic stroke patients within 24 hours of onset with DWI. MACIs were present in 20 patients (16.8%). During the follow up period, t here were 15 recurrent strokes, 3 acute coronary syndromes, and 5 deaths. MACI w as the only significant independent predictor for vascular events and death (odd ratio [OR]= 4.34; p = 0.001) and stroke recurrence (OR = 5.93; p = 0.001).

关键词：弥散加权成像急性缺血性中风成像研究急性冠脉综合征心血管事件

Proposed nomenclature for Pseudallescheria,Scedosporium and related genera

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Fungal Diversity 2014年第4期67卷 1-10页

作者： Michaela Lackner G.Sybren de Hoog Liyue Yang Leandro Ferreira Moreno Sarah A.Ahmed Fritz Andreas Josef Kaltseis Markus Nagl Cornelia Lass-Florl Brigitte Risslegger Gunter Rambach Cornelia Speth Vincent Robert Walter Buzina Sharon Chen Jean-Philippe Bouchara Jose F.Cano-Lira Josep Guarro Josepa Gené Fabiola Fernández Silva Rosa Haido Gerhard Haase Vladimir Havlicek Dea Garcia-Hermoso Jacques F.Meis Ferry Hagen Martin Kirchmair Johannes rainer Katharina Schwabenbauer Mirjam Zoderer Wieland Meyer Felix Gilgado Vania A.Vicente Elena Piecková Monika Regenermel Peter-Michael Rath Joerg Steinmann Xisto Wellington de Alencar Francoise Symoens Kathrin Tintelnot Krzysztof Ulfig Aristea Velegraki Anna Maria Tortorano Sandrine Giraud Sara Mina Kinga Rigler-Hohenwarter Fernando L.Hernando Andoni Ramirez-Garcia Aize Pellon Jashanpreet Kaur Eliana Barreto Bergter Jardel Vieira de Meirelles Ingrid Dutra da Silva Laurence Delhaes Ana Alastruey-Izquerdo Ruo-yu Li Qiaoyun Lu Tarek Moussa Omar Almaghrabi Hassan Al-Zahrani Gen Okada Shuwen Deng Wangqing Liao Jingsi Zeng Jouni Issakainen Livia Cristina Liporagi Lopes Division of Hygiene and Medical Microbiology Innsbruck Medical UniversityInnsbruckAustria CBS Fungal Biodiversity Centre UtrechtThe Netherlands Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamThe Netherlands Sun Yat-Sen Memorial Hospital Sun Yat-Sen UniversityGuangzhouChina Medical University of Graz GrazAustria Centre for Infectious Diseases and Microbiology Westmead HospitalWestmeadAustralia Laboratoire de Parasitologie-Mycologie Centre Hospitalier UniversitaireAngersFrance Unitats de Microbiologia i d’Anatomia Patològica Facultat de Medicina i Ciències de la Salut IISPVUniversitat Rovira i VirgiliReusSpain Universidade Federal do Estado do Rio de Janeiro Rio de JaneiroBrazil Institute of Medical Microbiology University Hospital RWTHAachenGermany Institute of Microbiology Academy of SciencesPragueCzech Republic Institut Pasteur Unitéde Mycologie MoléculaireCentre National de Référence Mycoses Invasives et AntifongiquesParisFrance Department of Medical Microbiology and Infectious Diseases Canisius-Wilhelmina HospitalNijmegenThe Netherlands Department of Medical Microbiology RadboudumcNijmegenThe Netherlands Institute of Microbiology eopold-Franzens-University InnsbruckInnsbruckAustria Molecular Mycology Research Laboratory Centre for Infectious Diseases and MicrobiologySydneyMedical School—Westmead HospitalMarie Bashir Institute for Infectious Diseases and BiosecurityThe University of SydneyWestmead Millennium InstituteWestmeadNSWAustralia Basic Pathology Department Federal University of ParanáStateCuritibaParanáBrazil Fellowship from Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq) BrasíliaBrazil Institute of Preventive and Clinical Medicine BratislavaSlovakia Institut für Hygiene und Mikrobiologie Landesklinikum St.Pölten St.PöltenAustria Institute of Medical Microbiology University Hospital EssenEssenGermany Nursing School of Unigranrio Rio de JaneiroBrazil Scientific Institute of Public Health Culture Collectio

As a result of fundamental changes in the International Code of Nomenclature on the use of separate names for sexual and asexual stages of fungi,generic names of many groups should be *** of the ECMM/ISHAM working group on Pseudallescheria/Scedosporium infections herein advocate a novel nomenclature for genera and species in Pseudallescheria,Scedosporium and allied *** generic names Parascedosporium,Lomentospora,Petriella,Petriellopsis,and Scedosporium are proposed for a lineage within Microascaceae with mostly Scedosporium anamorphs producing slimy,annellidic *** that Scedosporium has priority over Pseudallescheria and that Scedosporium prolificans is phylogenetically distinct from the other Scedosporium species,some name changes are *** minutispora and Petriellidium desertorum are renamed as Scedosporium minutisporum and ***,*** prolificans is renamed as Lomentospora prolificans.

关键词： Graphium Lomentospora Petriella Scedosporium apiospermum complex Microascaceae Nomenclature

Association of mineral and bone biomarkers with adverse cardiovascular outcomes and mortality in the German Chronic Kidney Disease(GCKD)cohort

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Bone Research 2023年第4期11卷 764-771页

作者： Katharina Charlotte Reimer Jennifer Nadal Heike Meiselbach Matthias Schmid Ulla T.Schultheiss Fruzsina Kotsis Helena Stockmann Nele Friedrich Matthias Nauck Vera Krane Kai-Uwe Eckardt Markus P.Schneider Rafael Kramann Jürgen Floege Turgay Saritas Department of Nephrology Rheumatologyand Clinical ImmunologyUniversity Hospital RWTH AachenAachenGermany Institute of Experimental Medicine and Systems Biology RWTH Aachen UniversityAachenGermany Institute for Cell and Tumor Biology RWTH Aachen UniversityAachenGermany Institute of Medical Biometry Informatics and EpidemiologyUniversity Hospital of BonnBonnGermany Department of Nephrology and Hypertension University of Erlangen-NürnbergErlangenGermany Institute of Genetic Epidemiology Faculty of Medicine and Medical Center-University of FreiburgFreiburgGermany Department of Medicine IV-Nephrology and Primary Care Faculty of Medicine and Medical Center-University of FreiburgFreiburgGermany Department of Nephrology and Medical Intensive Care Charité-Universitätsmedizin BerlinBerlinGermany Department of Nephrology University Medical Center RegensburgRegensburgGermany Institute of Clinical Chemistry and Laboratory Medicine University Medicine GreifswaldGreifswaldGermany DZHK(German Centre for Cardiovascular Research) Partner Site GreifswaldUniversity MedicineGreifswaldGermany Department of Medicine I Division of NephrologyUniversity Hospital WürzburgWürzburgGermany

Mineral and bone disorder(MBD)in chronic kidney disease(CKD)is tightly linked to cardiovascular disease(CVD).In this study,we aimed to compare the prognostic value of nine MBD biomarkers to determine those associated best with adverse cardiovascular(CV)outcomes and *** 5217 participants of the German CKD(GCKD)study enrolled with an estimated glomerular filtration rate(eG FR)between 30–60 mL·min-1 per 1.73 m2 or overt proteinuria,serum osteoprotegerin(OPG),C-terminal fibroblast growth factor-23(FGF23),intact parathyroid hormone(iP TH),bone alkaline phosphatase(BAP),cross-linked C-telopeptide of type 1 collagen(CTX1),procollagen 1intact N-terminal propeptide(P1NP),phosphate,calcium,and 25-OH vitamin D were measured at *** with missing values among these parameters(n=971)were excluded,leaving a total of 4246 participants for *** a median follow-up of6.5 years,387 non-CV deaths,173 CV deaths,645 nonfatal major adverse CV events(MACEs)and 368 hospitalizations for congestive heart failure(CHF)were *** and FGF23 were associated with all outcomes,with the highest hazard ratios(HRs)for *** the final Cox regression model,adjusted for CV risk factors,including kidney function and all other investigated biomarkers,each standard deviation increase in OPG was associated with non-CV death(HR 1.76,95%CI:1.35–2.30),CV death(HR 2.18,95%CI:1.50–3.16),MACE(HR 1.38,95%CI:1.12–1.71)and hospitalization for CHF(HR 2.05,95%CI:1.56–2.69).Out of the nine biomarkers examined,stratification based on serum OPG best identified the CKD patients who were at the highest risk for any adverse CV outcome and mortality.

关键词： Kidney cardiovascular vitamin

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阿尔茨海默病的改善途径：孟德尔随机分析

英国医学杂志中文版 2018年第5期21卷 243-243页

作者：王翠娣(译) 北京医院神经内科

目的明确哪项潜在可调整的风险因素与阿尔茨海默病相关，包括社会经济、生活方式、饮食、心脏代谢以及炎病因素。设计孟德尔随机化试验，使用与可调整风险因素相关的基因变异作为可观测变量。

关键词：阿尔茨海默病改善途径孟德尔随机分析

Correction to:Proposed nomenclature for Pseudallescheria,Scedosporium and related genera

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Fungal Diversity 2022年第2期113卷 193-194页

作者： Michaela Lackner G.Sybren de Hoog Liyue Yang Leandro Ferreira Moreno Sarah A.Ahmed Fritz Andreas Josef Kaltseis Markus Nagl Cornelia Lass-Florl Brigitte Risslegger Gunter Rambach Cornelia Speth Vincent Robert Walter Buzina Sharon Chen Jean-Philippe Bouchara Jose F.Cano-Lira Josep Guarro Josepa Gene Fabiola Fernandez Silva Rosa Haido Gerhard Haase Vladimir Havlicek Dea Garcia-Hermoso Jacques F.Meis Ferry Hagen Martin Kirchmair Johannes rainer Katharina Schwabenbauer Mirjam Zoderer Wieland Meyer Felix Gilgado Vania A.Vicente Elena Pieckova Monika Regenermel Peter-Michael Rath Joerg Steinmann Xisto Wellington de Alencar Françoise Symoens Kathrin Tintelnot Krzysztof Ulfig Aristea Velegraki Anna Maria Tortorano Sandrine Giraud Sara Mina Kinga Rigler-Hohenwarter Fernando L.Hernando Andoni Ramirez-Garcia Aize Pellon Jashanpreet Kaur Eliana Barreto Bergter Jardel Vieira de Meirelles Ingrid Dutra da Silva Laurence Delhaes Ana Alastruey-Izquierdo Ruo-yu Li Qiaoyun Lu Tarek Moussa Omar Almaghrabi Hassan Al-Zahrani Gen Okada Shuwen Deng Wangqing Liao Jingsi Zeng Jouni Issakainen Livia Cristina Liporagi Lopes Division of Hygiene and Medical Microbiology Innsbruck Medical UniversityInnsbruckAustria CBS Fungal Biodiversity Centre UtrechtThe Netherlands Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamThe Netherlands Sun Yat-Sen Memorial Hospital Sun Yat-Sen UniversityGuangzhouChina Medical University of Graz GrazAustria Centre for Infectious Diseases and Microbiology Westmead HospitalWestmeadAustralia Laboratoire de Parasitologie-Mycologie Centre Hospitalier UniversitaireAngersFrance Unitats de Microbiologia i d’Anatomia Patologica Facultat de Medicina i Ciencies de la Salut IISPVUniversitat Rovira i VirgiliReusSpain Universidade Federal do Estado do Rio de Janeiro Rio de JaneiroBrazil Institute of Medical Microbiology University Hospital RWTHAachenGermany Institute of Microbiology Academy of SciencesPragueCzech Republic Institut Pasteur Unite de Mycologie MoleculaireCentre National de Reference Mycoses Invasives et AntifongiquesParisFrance Department of Medical Microbiology and Infectious Diseases Canisius-Wilhelmina HospitalNijmegenThe Netherlands Department of Medical Microbiology RadboudumcNijmegenThe Netherlands Institute of Microbiology eopold-Franzens-University InnsbruckInnsbruckAustria Molecular Mycology Research Laboratory Centre for Infectious Diseases and MicrobiologySydneyMedical School—Westmead HospitalMarie Bashir Institute for Infectious Diseases and BiosecurityThe University of SydneyWestmead Millennium InstituteWestmeadNSWAustralia Basic Pathology Department Federal University of Parana StateCuritibaParanaBrazil Fellowship from Conselho Nacional de Desenvolvimento Cientifico e Tecnologico(CNPq) BrasiliaBrazil Institute of Preventive and Clinical Medicine BratislavaSlovakia Institut für Hygiene und Mikrobiologie Landesklinikum St.Pölten St.PoltenAustria Institute of Medical Microbiology University Hospital EssenEssenGermany Nursing School of Unigranrio Rio de JaneiroBrazil Scientific Institute of Public Health Culture Collect

三环咔唑生物碱Neocarazostatin A生物合成中特殊的异戊烯基化和羟基化修饰

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科学新闻 2016年第1期 136-136页

作者：黄胜 Somayah Sameer Elsayed Meinan Lv Jioji Tabudravu Mostafa E.Rateb Roland Gyampoh Kwaku Kyeremeh rainer Ebel Marcel Jaspars Zixin Deng 虞沂 Hai Deng 武汉大学药学院湖北民族学院医学院

文章简介Neocarazostatin A是微生物来源三环咔唑生物碱家族的代表性化合物,具有很强的自由基清除活性。同位素喂养实验显示其生物合成前体完全不同于已报道的植物来源咔唑碱,因此引起了科学家们的浓厚兴趣。研究人员通过化学挖掘、基... 详细信息

文章简介Neocarazostatin A是微生物来源三环咔唑生物碱家族的代表性化合物,具有很强的自由基清除活性。同位素喂养实验显示其生物合成前体完全不同于已报道的植物来源咔唑碱,因此引起了科学家们的浓厚兴趣。研究人员通过化学挖掘、基因敲除、酶的体外功能表征等手段,对Neocarazostatin A的生物合成途径进行了深入解析。研究结果证明,Neocarazostatin A的生物合成起始于色氨酸,后者经过一系列复杂的生化反应完成咔唑骨架的组装,再经过脱羧、环化、重排等一系列

关键词：生物合成生化反应咔唑生物碱 Neocarazostatin A