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Expressive line drawings of human faces from range images

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Science in China(Series F) 2009年第2期52卷 295-307页

作者： HUANG YueZhu MARTIN Ralph R. rosin paul l. MENG XiangXu YANG Chenglei Department of Computer Science and Technology Shandong University Jinan 250101 China School of Computer Science Cardiff University Cardiff United Kingdom

We propose a novel technique to extract features from a range image and use them to produce a 3D pen-and-ink style portrait similar to a traditional artistic drawing. Unlike most previous template-based, component-based or example-based face sketching methods, which work from a frontal photograph as input, our system uses a range image as input. Our method runs in real-time for models of moderate complexity, allowing the pose and drawing style to be modified interactively. Portrait drawing in our system makes use of occluding contours and suggestive contours as the most important shape cues. However, current 3D feature line detection methods require a smooth mesh and cannot be reliably applied directly to noisy range images. We thus present an improved silhouette line detection algorithm. Feature edges related to the significant parts of a face are extracted from the range image, connected, and smoothed, allowing us to construct chains of line paths which can then be rendered as desired. We also incorporate various portrait-drawing principles to provide several simple yet effective non- photorealistic portrait renderers such as a pen-and-ink shader, a hatch shader and a sketch shader. These are able to generate various life-like impressions in different styles from a user-chosen viewpoint. To obtain satisfactory results, we refine rendered output by smoothing changes in line thickness and opacity. We are careful to provide appropriate visual cues to enhance the viewer＇s comprehension of the human face. Our experimental results demonstrate the robustness and effectiveness of our approach, and further suggest that our approach can be extended to other 3D geometric objects.

关键词： portrait drawing non-photorealistic rendering line drawing suggestive contour occluding contour feature line stylization

Targeting BCl9/BCl9l enhances antigen presentation by promoting conventional type 1 dendritic cell(cDC1)activation and tumor infiltration

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2804-2818页

作者： Fenglian He Zhongen Wu Chenglong liu Yuanyuan Zhu Yan Zhou Enming Tian Rina rosin-Arbesfeld Dehua Yang Ming-Wei Wang Di Zhu Department of Pharmacology Minhang Hospitaland Key Laboratory of Smart Drug DeliveryShanghai Engineering Research Center of Immune TherapySchool of PharmacyFudan UniversityShanghai 201203China The National Center for Drug Screening and the CAS Key laboratory of Receptor Research Shanghai Institute of Materia MedicaChinese Academy of Sciences(CAS)Shanghai 201203China Department of Microbiology and Immunology Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael Department of Pharmacology School of Basic Medical SciencesFudan UniversityShanghai 200032China Research Center for Deepsea Bioresources SanyaChina Department of Chemistry School of ScienceThe University of TokyoTokyoJapan Engineering Research Center of Tropical Medicine Innovation and Transformation of Ministry of Education School of PharmacyHainan Medical UniversityHaikouChina Shandong Academy of Pharmaceutical Science JinanChina

Conventional type 1 dendritic cells(cDC1)are the essential antigen-presenting DC subset in antitumor *** B-cell lymphoma 9 and B-cell lymphoma 9-like(BCl9/BCl9l)inhibits tumor growth and boosts immune responses against ***,whether oncogenic BCl9/BCl9l impairs antigen presentation in tumors is still not completely ***,we show that targeting BCl9/BCl9l enhanced antigen presentation by stimulating cDC1 activation and infiltration into *** inhibition of BCl9/BCl9l with a novel inhibitor hsBCl9z96 or Bcl9/Bcl9l knockout mice markedly delayed tumor growth and promoted antitumor CD8^(+)T cell ***,targeting BCl9/BCl9l promoted antigen presentation in *** is due to the increase of cDC1 activation and tumor infiltration by the XCl1-XCR1 ***,using single-cell transcriptomics analysis,we found that Bcl9/Bcl9l deficient cDC1 were superior to wild-type(WT)cDC1 at activation and antigen presentation via NF-κB/IRF1 ***,we demonstrate that targeting BCl9/BCl9l plays a crucial role in cDC1-modulated antigen presentation of tumor-derived antigens,as well as CD8^(+)T cell activation and tumor *** BCl9/BCl9l to regulate cDC1 function and directly orchestrate a positive feedback loop necessary for optimal antitumor immunity could serve as a potential strategy to counter immune suppression and enhance cancer immunotherapy.

关键词： immunity Targeting markedly

Integration of multiple flexible electrodes for realtime detection of barrier formation with spatial resolution in a gut-on-chip system

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Microsystems & Nanoengineering 2024年第1期10卷 105-114页

作者： Mara lucchetti Gabriel Werr Sofia Johansson laurent Barbe léa Grandmougin paul Wilmes Maria Tenje luxembourg Centre for Systems Biomedicine(lCSB) University of LuxembourgEsch-sur-Alzette L-4362Luxembourg Division of Biomedical Engineering Department of Materials Science and EngineeringScience for Life LaboratoryUppsala University75121 UppsalaSweden Department of life Sciences and Medicine Faculty of ScienceTechnology and MedicineUniversity of LuxembourgEsch-sur-Alzette L-4362Luxembourg

In healthy individuals,the intestinal epithelium forms a tight barrier to prevent gut bacteria from reaching blood *** study the effect of probiotics,dietary compounds and drugs on gut barrier formation and disruption,human gut epithelial and bacterial cells can be cocultured in an in vitro model called the human microbial crosstalk(HuMiX)gut-on-a-chip ***,we present the design,fabrication and integration of thin-film electrodes into the HuMiX platform to measure transepithelial electrical resistance(TEER)as a direct readout on barrier tightness in *** various aspects of the HuMiX platform have already been set in their design,such as multiple compressible layers,uneven surfaces and nontransparent materials,a novel fabrication method was developed whereby thin-film metal electrodes were first deposited on flexible substrates and sequentially integrated with the HuMiX system via a transfer-tape ***,to measure localized TEER along the cell culture chamber,we integrated multiple electrodes that were connected to an impedance analyzer via a *** further developed a dynamic normalization method because the active measurement area depends on the measured TEER *** fabrication process and system setup can be applicable to other barrier-on-chip *** a proof-of-concept,we measured the barrier formation of a cancerous Caco-2 cell line in real-time,which was mapped at four spatially separated positions along the HuMiX culture area.

关键词： barrier system multiple

Quantifying source-sink relationships in leaf-color modified rice genotypes during grain filling

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Journal of Integrative Agriculture 2024年第9期23卷 2923-2940页

作者： Zhenxiang Zhou paul CStruik Junfei Gu Peter E.l.van der Putten Zhiqin Wang Jianchang Yang Xinyou Yin Centre for Crop Systems Analysis Department of Plant SciencesWageningen University&ResearchWageningen 6700 AKThe Netherlands College of Agriculture Yangzhou UniversityYangzhou 225009China

leaf-color modification can affect canopy photosynthesis,with potential effects on rice yield and yield *** source-sink relationships through crop management is often used to improve crop *** study investigated whether and how modifying leaf color alters source-sink relationships and whether current crop cultivation practices remain applicable for leaf-color modified *** collected data of total biomass and nitrogen(N)accumulation in rice genotypes of four genetic backgrounds and their leaf-color modified variants(greener or yellower)were analyzed,using a recently established modelling method to quantify the source-sink(im)balance during grain *** all leaf-color variants,only one yellower-leaf variant showed a higher source capacity than its normal *** was associated with greater post-flowering N-uptake that prolonged the functional leaf-N duration,and this greater post-flowering N-uptake was possible because of reduced pre-flowering N-uptake.A density experiment showed that current management practices(insufficient planting density accompanied by abundant N application)are unsuitable for the yellower-leaf genotype,ultimately limiting its yield ***-color modification affects source-sink relationships by regulating the N trade-off between pre-and post-flowering uptake,as well as N translocation between source and sink *** best exploit leaf-color modification for improving crop productivity,adjustments of crop management practices are required.

关键词： source-sink relationship biomass nitrogen Oryza sativa leaf-color modification

Surface engineering with ionic polymers on membranes for boron removal

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Frontiers of Chemical Science and Engineering 2024年第5期18卷 61-69页

作者： Xiting Zhang Chenyi Fang J paul Chen Sui Zhang Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore 117576Singapore Department of Civil and Environmental Engineering National University of SingaporeSingapore 119260Singapore College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060China

Removal of boric acid from seawater and wastewater using reverse osmosis membrane technologies is imperative and yet remains inadequately addressed by current commercial *** research efforts performed post-modification of reverse osmosis membranes to enhance boron rejection,which is usually accompanied by substantial sacrifice in water *** study delves into the surface engineering of low-pressure reverse osmosis membranes,aiming to elevate boron removal efficiency while maintaining optimal salt rejection and water *** were modified by the self-polymerization and co-deposition of dopamine and polystyrene sulfonate at varying ratios and *** surfaces became smoother and more hydrophilic after *** optimum membrane exhibited a water permeability of 9.2±0.1 l·m^(-2)·h^(-1)·bar^(-1),NaCl rejection of 95.8%±0.3%,and boron rejection of 49.7%±0.1% and 99.6%±0.3% at neutral and alkaline pH,*** water permeability is reduced by less than 15%,while the boron rejection is 3.7 times higher compared to the blank *** research provides a promising avenue for enhancing boron removal in reverse osmosis membranes and addressing water quality concerns in the desalination process.

关键词： membrane low-pressure reverse osmosis boron surface engineering

Post-fire recovery of Puya raimondii, vegetation and birds in the puna of Huascarán National Park, Perú

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Journal of Mountain Science 2024年第1期21卷 20-32页

作者： Mery l.SUNI Giovana P.VADIllO César ARANA Enoc JARA-PENA letty SAlINAS M.Estela PONCE paul M.RAMSAY Plant Physiology laboratory Faculty of Biological SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Natural History Museum Universidad Nacional Mayor de San MarcosLima 15072Peru Applied Phytology laboratory Faculty of Biological SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Department of Statistics Faculty of Mathematical SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Department of Chemical and Biological Sciences Universidad de las Américas PueblaSan Andrés Cholula CP Cholula CP 72810Mexico

A large fire of 233 ha in Huascarán National Park in Peru provided an opportunity to compare plant and bird responses in burned and nearby unburned zones of the puna. Heights and live diameters of flagship Puya raimondii rosettes(assigned to four broad developmental phases), plant communities(66 species in 24 families and nine growth forms) and bird communities(77 species in six trophic guilds) were monitored after the fire. Although no mortality was observed, Puya raimondii plants were affected by the fire, losing approximately 60% of their photosynthetic area across all developmental phases, but recovered quickly during the first two years after fire. The comparison of Puya rosette recovery after fire was complicated by the changes in live rosette diameter for unburned plants, which showed plasticity of photosynthetic area linked to seasonal and annual fluctuations in precipitation in this relatively dry environment(decreased by 26% for mature adult plants over the study period). Fire caused an immediate change in the density, biomass and composition of vegetation. Although the species present remained similar, their abundances changed significantly immediately after the fire, with notable reductions in dominant tussock grasses. This provided opportunities for other plants, resulting in higher postfire diversity of plant species, genera, families and growth forms. In turn, the changes in vegetation after fire affected the composition of birds according to their trophic guild. Granivores largely disappeared,generalists were mostly unaffected, and other guilds showed a more complex response. As the vegetation recovered, most displaced birds returned within approximately one year.

关键词： Burning Plant biomass Trophic guilds Andes Giant rosette plants

Edge-Aware level Set Diffusion and Bilateral Filtering Reconstruction for Image Magnification

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Journal of Computer Science & Technology 2009年第4期24卷 734-744页

作者：黄华臧彧 paul l.rosin 齐春 School of Electronics and Information Engineering Xi'an Jiaotong University Xi'an 710049 China School of Computer Science Cardiff University Cardiff U.K.

In this paper we propose an image magnification reconstruction method. In recent years many interpolation algorithms have been proposed for image magnification, but all of them have defects to some degree, such as jaggies and blurring. To solve these problems, we propose applying post-processing which consists of edge-aware level set diffusion and bilateral filtering. After the initial interpolation, the contours of the image are identified. Next, edge-aware level set diffusion is applied to these significant contours to remove the jaggies, followed by bilateral filtering at the same locations to reduce the blurring created by the initial interpolation and level set diffusion. These processes produce sharp contours without jaggies and preserve the details of the image. Results show that the overall RMS error of our method barely increases while the contour smoothness and sharpness are substantially improved.

关键词： computer application image magnification reconstruction edge-aware level set diffusion bilateral filtering

The penetration depth of atomic radicals in tubes with catalytic surface properties

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Plasma Science and Technology 2024年第7期26卷 157-164页

作者： Domen paul Miran MOZETIC Rok ZAPlOTNIK Alenka VESEl Gregor PRIMC Denis DONlAGIC Jozef Stefan Institute Jamova Cesta 39Ljubljana 1000Slovenia Jozef Stefan International Postgraduate School Jamova Cesta 39Ljubljana 1000Slovenia Faculty of Electrical Engineering and Computer Science University of MariborKoroska Cesta 46Maribor 2000Slovenia

Catalysis of molecular radicals is often performed in interesting experimental *** possible configuration is tubular *** radicals are introduced into the tubes on one side,and stable molecules are exhausted on the other *** penetration depth of radicals depends on numerous parameters,so it is not always feasible to calculate *** article presents systematic measurements of the penetration depth of oxygen atoms along tubes made from nickel,cobalt,and *** source of O atoms was a surfatron-type microwave *** initial density of O atoms depended on the gas flow and was 0.7×10^(21)m^(-3),2.4×10^(21)m^(-3),and 4.2×10^(21)m^(-3)at the flow rates of 50,300,and 600 sccm,and pressures of 10,35,and 60 Pa,*** gas temperature remained at room temperature throughout the *** dissociation fraction decreased exponentially along the length of the tubes in all *** penetration depths for well-oxidized nickel were 1.2,1.7,and 2.4 cm,*** cobalt,they were slightly lower at 1.0,1.3,and 1.6 cm,respectively,while for copper,they were 1.1,1.3,and 1.7 cm,*** results were explained by gas dynamics and heterogeneous surface *** data are useful in any attempt to estimate the loss of molecular fragments along tubes,which serve as catalysts for the association of various radicals to stable molecules.

关键词： oxygen plasma penetration depth catalysis heterogeneous surface recombination atom loss

New insights into protein–polysaccharide complex coacervation:Dynamics,molecular parameters,and applications

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Aggregate 2024年第1期5卷 148-166页

作者： Jiabao Zheng paul Van der Meeren Weizheng Sun School of Food Science and Engineering South China University of TechnologyGuangzhouChina Department of Green Chemistry and Technology Faculty of Bioscience EngineeringGhent UniversityGhentBelgium Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health(111 Center) GuangzhouChina

For more than a decade,the discovery of liquid–liquid phase separation within living organisms has prompted colloid scientists to understand the connection between coacervate functionality,phase behavior,and dynamics at a multidisciplinary *** the protein–polysaccharide was the first system in which the coacervation phenomenon was discovered and is widely used in food systems,the phase state and relaxation dynamics of protein–polysaccharide complex coacervates(PPCC)have rarely been discussed ***,this review aims to unravel the relationship between PPCC dynamics,thermodynamics,molecular architecture,applications,and phase states in past *** ahead,solving the way molecular architecture spreads to macro-functionality,that is,establishing the relationship between molecular architecture–dynamics–application,will catalyze novel advancements in PPCC research within the field of foods and biomaterials.

关键词： dynamics encapsulation liquid coacervate protein-polysaccharide complex coacervation solid precipitate