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Journal of Mountain Science 2020年第5期17卷 1013-1031页

作者： SERRANO Enrique LóPEZ-MORENO Juan Ignacio GóMEZ-LENDE Manuel PISABARRO Alfonso MARTíN-MORENO Raúl rico ibai ALONSO-GONZáLEZ Esteban Dept of GeographyUniversity of ValladolidValladolid 47011Spain Dept of Geoenvironmental Processes and Global ChangePyrenean Institute of EcologyZaragoza 50.080Spain Dept.Specific Didactics.Autonom University of Madrid.Madrid 28049Spain Dept of GeographyPrehistory and ArcheologyUniversity of the Basque CountryVitoria 01006Spain

Seasonally frozen ground,mountain permafrost and cryogenic geomorphological processes are important components of the Pyrenean high *** work presents the results of a study on the distribution of frozen ground in a marginal and paraglacial environment of temperate *** inventory was made of landforms and indicators of frozen ground,and frozen ground was mapped *** 2014 and 2016 ground temperatures and thermal regimes were monitored,basal temperatures of snow-cover(BTS)were measured and a thermal map was *** thermal behaviours were detected among different elevations and slope *** processes are the most widespread,in which frost weathering and nivation,together with gelifluction and cryoturbation,are the most efficient processes;the latter two are generally linked to the presence of frozen *** fall in air and ground temperatures with altitude,slope orientations,and snowpack thickness and evolution determine ground thermal *** the study area,three types of thermal regimes were established:climate-controlled,snowcover-controlled,and frozen *** frozen ground occurs across a broad range of elevation between 2650 and 3075 m asl,whereas possible permafrost only occurs above 2750 m asl.

关键词： Geomorphology Periglacial Seasonally frozen ground Mountain permafrost Pyrenees

Human health risks associated to trace elements and metals in commercial fish from the Brazilian Amazon

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Journal of Environmental Sciences 2025年第2期148卷 230-242页

作者： Andrea V.Waichman Gabriel Silva de Souza Nunes Rhaul de Oliveira Isabel López-Heras Andreu rico Federal University of the Amazon Institute of Biological SciencesAv.Rodrigo Ramos 3000Manaus 69077-000Brazil Federal University of Pernambuco Department of ZoologyAv.Prof Moraes Rego 1235Cidade UniversitáriaRecife 50670-901Brazil University of Campinas School of TechnologyRua Paschoal Marmo 1888-Jd.Nova ItáliaLimeira 13484-332Brazil IMDEA Water Institute Science and Technology Campus of the University of AlcaláAv.Punto Com 2Alcaláde Henares 28805MadridSpain Cavanilles Institute of Biodiversity and Evolutionary Biology University of Valenciac/Catedrático JoséBeltrán 246980PaternaValenciaSpain

Fish constitutes the main protein source for the Amazonian ***,the impact of different anthropogenic activities on trace element and metal accumulation in fish and their risks for human health at a regional scale remain largely *** we assessed exposure levels of 10 trace elements andmetals(Cr,Mn,Fe,Ni,Cu,Zn,As,Cd,Pb,and Hg)in 56 samples belonging to 11 different species of fish from the Brazilian *** studied the relationship between exposure levels,fish origin,and fish feeding habits,and assessed toxicological and carcinogenic risks for the Amazonian *** significant correlation was found between sampling site and exposure levels to the studied elements,but a significant difference was found between the accumulation of some metals and the position of the fish species in the food *** concentrations of Cr and Hg in fish flesh were found to exceed the Brazilian limits for human *** study shows that current fish consumption patterns can lead to estimated daily intakes of Hg,As and Cr that exceed the oral reference dose,thus posing a toxicological ***,carcinogenic risks may be expected due to the continued exposure to Cr and *** results of this study show that the consumption of wild caught fish in the Amazon region should be ***,continued monitoring of trace element and metal contamination in fish and on the health of the Amazonian population is recommended,particularly for riverine and indigenous communities.

关键词： Metals Deforestation Mining Freshwater ecosystems Carcinogenic risks Amazon

Evaluation of suprachiasmatic nucleus in Alzheimer’s disease with non-invasive magnetic resonance methods

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Neural Regeneration Research 2022年第8期17卷 1753-1754页

作者： rico Singer A.Alia Leiden Institute of Chemistry Leiden UniversityLeidenThe Netherlands Institute of Medical Physics and Biophysics University of LeipzigLeipzigGermany

The suprachiasmatic nucleus and Alzheimer’s disease(AD):AD is the most frequently diagnosed form of dementia,with the total number of AD patients worldwide expected to triple by 2050 compared to 2015(Prince et al.,2015).Despite years of research,much of the AD pathology remains unclear with no treatment or cure *** its two hallmarks,amyloid-β(Aβ)plagues and hyperphosphorylated tau tangles,a distortion of circadian rhythms is commonly ***,poor sleep quality or trouble falling asleep are common AD symptoms,sometimes developing 10-15 years before cognitive symptoms associated with AD(Ju et al.,2014).

关键词： al. Alzheimer supra

Process Design for Hybrid Sheet Metal Components

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Acta Metallurgica Sinica(English Letters) 2015年第12期28卷 1518-1524页

作者： rico Haase Roland Müller Dirk Landgrebe Peter Scholz Matthias Riemer Fraunhofer Institute for Machine Tools and Forming Technology IWU

The global trends towards improving fuel efficiency and reducing CO;emissions are the key drivers for lightweight solutions. In sheet metal processing, this can be achieved by the use of materials with a supreme strength-toweight and stiffness-to-weight ratio. Besides monolithic materials such as high-strength or light metals, in particular metal–plastic composite sheets are able to provide outstanding mechanical properties. Thus, the adaption of conventional, wellestablished forming methods for the processing of hybrid sheet metals is a current challenge for the sheet metal working industry. In this work, the planning phase for a conventional sheet metal forming process is studied aiming at the forming of metal–plastic composite sheets. The single process steps like material characterization, FE analysis, tool design and development of robust process parameters are studied in detail and adapted to the specific properties of metal–plastic composites. In material characterization, the model of the hybrid laminate needs to represent not only the mechanical properties of the individual combined materials, but also needs to reflect the behaviour of the interface zone between *** on experience, there is a strong dependency on temperature as well as strain rate. While monolithic materials show a moderate anisotropic behaviour, loads on laminates in different directions generate different strain states and completely different failure modes. During the FE analysis, thermo-mechanic and thermo-dynamic effects influence the temperature distribution within tool and work pieces and subsequently the forming behaviour. During try out and production phase,those additional influencing factors are limiting the process window even more and therefore need to be considered for the design of a robust forming process. A roadmap for sheet metal forming adjusted to metal–plastic composites is presented in this paper.

关键词： Characterization Hybrids Interface Layered structures Processing Sheet forming

To supervise or to self‑supervise:a machine learning based comparison on credit supervision

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Financial Innovation 2021年第1期7卷 562-582页

作者： JoséAmérico Pereira Antunes Central Bank of Brazil Av Presidente Vargas730Rio de Janeiro 20231‑044Brazil

This study investigates the need for credit supervision as conducted by on-site banking *** builds on a real bank on-site credit examination to compare the performance of a hypothetical self-supervision approach,in which banks themselves assess their loan portfolios without external intervention,with the on-site banking supervision approach of the Central Bank of *** experiment develops two machine learning classification models:the first model is based on good and bad ratings informed by banks,and the second model is based on past on-site credit portfolio examinations conducted by banking *** findings show that the overall performance of the on-site supervision approach is consistently higher than the performance of the self-supervision approach,justifying the need for on-site credit portfolio examination as conducted by the Central Bank.

关键词： Bank supervision Machine learning Loan loss provisions On-site credit supervision

The carbon fluxes in different successional stages:modelling the dynamics of tropical montane forests in South Ecuador

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Forest Ecosystems 2017年第2期4卷 143-153页

作者： sebastian paulick claudia dislich jürgen homeier rico fischer andreas huth Department of Ecological Modelling Helmholtz Centre for Environmental Research-UFZPermoserstr1504318 LeipzigGermany Georg-August-University Gottingen Plant EcologyUntere KarspOle 237073 GottingenGermany University of Osnabriick Institute of Environmental Systems ResearchBarbarastr1249076 OsnabruckGermany iDiv German Centre for Integrative Biodiversity Research(iDiv)Halle-Jena-LeipzigDeutscher Platz 5e04103 LeipzigGermany

Background： Tropical forests play an important role in the global carbon（C） ***, tropical montane forests have been studied less than tropical lowland forests, and their role in carbon storage is not well *** forests are highly endangered due to logging, land-use and climate *** objective was to analyse how the carbon balance changes during forest ***： In this study, we used a method to estimate local carbon balances that combined forest inventory data with process-based forest *** utilised such a forest model to study the carbon balance of a tropical montane forest in South Ecuador, comparing two topographical slope positions（ravines and lower slopes vs upper slopes and ridges）.Results： The simulation results showed that the forest acts as a carbon sink with a maximum net ecosystem exchange（NEE） of 9.3 Mg C？（ha？yr）-1during its early successional stage（0–100 years）.In the late successional stage, the simulated NEE fluctuated around zero and had a variation of 0.77 Mg C？（ha？yr）–*** simulated variability of the NEE was within the range of the field *** discovered several forest attributes（e.g., basal area or the relative amount of pioneer trees） that can serve as predictors for NEE for young forest stands（0–100 years） but not for those in the late successional stage（500–1,000 years）.In case of young forest stands these correlations are high, especially between stand basal area and ***： In this study, we used an Ecuadorian study site as an example of how to successfully link a forest model with forest inventory data, for estimating stem-diameter distributions, biomass and aboveground net primary *** conclude, this study shows that process-based forest models can be used to investigate the carbon balance of tropical montane *** this model it is possible to find hidden relationships between forest attributes and forest carbon *** relationships promote a better understandin

关键词： Forest model Tropical montane forest Forest succession Carbon balance Forest productivity FORMIND

Multi-objective Optimization of Production Scheduling Using Particle Swarm Optimization Algorithm for Hybrid Renewable Power Plants with Battery Energy Storage System

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Journal of Modern Power Systems and Clean Energy 2021年第2期9卷 285-294页

作者： Jon Martinez-rico Ekaitz Zulueta Ismael Ruiz de Argandona Unai Femandez-Gamiz Mikel Armendia The Automation and Control Unit Fundacion TeknikerBasque Research and Technology Alliance(BRTA)Ifiaki Goenaga520600 the University of the Basque Country Ing.Torres Quevedo148013 BilbaoSpain the Department of Systems Engineering and Control College of Engineering at Vitoria-GasteizUniversity of the Basque CountryNieves Cano1201006 Vitoria-GasteizSpain the Department of Nuclear and Fluid Mechanics College of Engineering at Vitoria-GasteizUniversity of the Basque CountryNieves Cano1201006 Vitoria-GasteizSpain

Considering the increasing integration of renewable energies into the power grid,batteries are expected to play a key role in the challenge of compensating the stochastic and intermittent nature of these energy ***,the deployment of batteries can increase the benefits of a renewable power *** way to increase the profits with batteries studied in this paper is performing energy *** strategy is based on storing energy at low electricity price moments and selling it when electricity price is *** this paper,a hybrid renewable energy system consisting of wind and solar power with batteries is studied,and an optimization process is conducted in order to maximize the benefits regarding the dayahead production scheduling of the plant.A multi-objective cost function is proposed,which,on the one hand,maximizes the obtained profit,and,on the other hand,reduces the loss of value of the battery.A particle swarm optimization algorithm is developed and fitted in order to solve this non-linear multi-objective *** the aim of analyzing the importance of considering both the energy efficiency of the battery and its loss of value,two more simplified cost functions are *** show the importance of including the energy efficiency in the cost function to ***,it is proven that the battery lifetime increases substantially by using the multi-objective cost function,whereas the profitability is similar to the one obtained in case the loss of value is not ***,due to the small difference in price among hours in the analyzed Iberian electricity market,it is observed that low profits can be provided to the plant by using batteries just for arbitrage purposes in the day-ahead market.

关键词： Battery energy storage system energy arbitrage hybrid renewable energy system particle swarm optimization

Zwitterionic and mesoionic liquids:Molecular aggregation in 3-methylsydnone

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Science China Chemistry 2010年第9期53卷 2063-2069页

作者： CASSEL Stéphanie rico-LATTES Isabelle LATTES Armand Laboratoire des IMRCP UMR 5623Université Paul Sabatier

Ionic liquids are green solvents with interesting properties:displaying low melting points and high boiling *** offer a new approach applicable in many ***,the presence of free ions can be a matter in some cases,*** the study of nucleophilic reactions,in electrochemistry,and in each situation where there is a competition between counter ions,as in micellization of ionic *** compounds having formal unit electrical charges of opposite sign,and the same physical properties than ionic liquids would be a nice alternative to these latter *** are two classes of chemical compounds having these characteristics:zwitterionic liquids(with no uncharged canonical representation) and mesoionic liquids(in which the negative and the positive charges are delocalized).In that last class we have chosen to work with 3-methylsydnone in order to examine,in this aprotic solvent,if it was possible to observe aggregation of surfactants in the same manner as in *** all kinds of surfactants studied(ionic,zwitterionic and mesoionic) we have been able to demonstrate the formation of direct micelles:hydrogen bonding is thus not mandatory for molecular *** of the behavior in water and in formamide showed that solvophobic interactions were qualitatively comparable but with a lower intensity.

关键词： ionic liquids zwitterionic liquids mesoionic liquids 3-methylsydnone molecular aggregation micellization solvophobicity

Refractive index measurement of dielectric samples using highly focused radially polarized light(Invited Paper)

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Chinese Optics Letters 2017年第3期15卷 12-15页

作者： Guadalupe López-Morales Victor-Manuel rico-Botero Rafael Espinosa-Luna Qiwen Zhan GIPYS Laboratory Centro de Investigaciones en Optica A. C. León Gto 37150 México Department of Electro-Optics and Photonics University of Dayton Dayton OH 45469 USA

In this Letter, a refractive index measurement of a dielectric sample using highly focused radially polarized light is reported. Through imaging analysis of the optical field at the pupil plane of a high numerical aperture （NA） objective lens reflected by the sample under study, the Brewster angle is found. Employing a high NA objective lens allows the measurement of multiple angles of incidence from 0° to 64° in a single shot. The refractive index of the sample is estimated using the measured Brewster angle. The experimental results are compared with the theoretical images computed with the Fresnel theory, and a good agreement is obtained.

关键词： high Refractive index measurement of dielectric samples using highly focused radially polarized light

Modulation of IL-10/IL-10R expression by mafosfamide, a derivative of 4-hydroxycyclophosphamide, in a rat B-cell lymphoma

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BIOCELL 2012年第2期36卷 91-95页

作者： MARÍA J.rico PABLO MATAR O.GRACIELA SCHAROVSKY Instituto de Genética Experimental Facultad de Ciencias MédicasUniversidad Nacional de RosarioSanta Fe 3100(2000)RosarioArgentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET). Consejo de Investigaciones UNRRosarioArgentina

We have already shown that IL-10 plays an important role in immunosuppression and metastatic dissemination in the rat B-cell lymphoma L-TACB *** was suggested that the up-regulation of IL10 production and IL-10 receptor(IL-10R)expression would be part of the transition from primary tumor to metastatic phenotype and that IL-10,besides its immunosuppressive activity,may act as a growth factor for metastatic L-TACB *** treatment of L-TACB-bearing rats with a single low-dose cyclophosphamide decreased IL-10 production,reverted immunosuppression and induced the immunologic rejection of tumor metastasis without any effect on primary tumor *** current aim was to investigate the effects of cyclophosphamide on the expression of IL-10 and IL-10R on primary and metastatic L-TACB *** that cyclophosphamide is a prodrug,we used mafosfamide,a compound that yields in vitro the same active metabolites as cyclophosphamide does in *** induced down-regulation of IL-10 production and IL-10R expression on metastatic cells and,concomitantly,inhibited metastatic cell *** suggest that mafosfamide would inhibit the regulatory loop mediated by the IL-10/IL-10R system and,as a consequence,metastatic cell *** results may have a considerable impact on the design of new therapies for metastatic lymphomas.

关键词： metastasis cyclophosphamide cell proliferation