Evaluation of suprachiasmatic nucleus in Alzheimer’s disease with non-invasive magnetic resonance methods

作     者：Rico Singer A.Alia Rico Singer;A.Alia

作者机构：Leiden Institute of ChemistryLeiden UniversityLeidenThe Netherlands Institute of Medical Physics and BiophysicsUniversity of LeipzigLeipzigGermany 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2022年第17卷第8期

页      面：1753-1754页

核心收录：

学科分类：1002[医学-临床医学] 100203[医学-老年医学] 10[医学] 

主　　题：al. Alzheimer supra 

摘      要：The suprachiasmatic nucleus and Alzheimer’s disease(AD):AD is the most frequently diagnosed form of dementia,with the total number of AD patients worldwide expected to triple by 2050 compared to 2015(Prince et al.,2015).Despite years of research,much of the AD pathology remains unclear with no treatment or cure *** its two hallmarks,amyloid-β(Aβ)plagues and hyperphosphorylated tau tangles,a distortion of circadian rhythms is commonly ***,poor sleep quality or trouble falling asleep are common AD symptoms,sometimes developing 10-15 years before cognitive symptoms associated with AD(Ju et al.,2014).