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Joint MAp channel estimation and data detection for OFDM in presence of phase noise from free running and phase locked loop oscillator

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Digital Communications and Networks 2021年第1期7卷 55-61页

作者： Kamayani Shrivastav r.p.yadav K.C.Jain Department of Electronics and Communication Malaviya National Institute of Technology302017India Department of Matiiematics Indian Institute of Information TechnologyKotaIndia

This paper addresses a computationally compact and statistically optimal joint Maximum a posteriori(MAp)algorithm for channel estimation and data detection in the presence of phase Noise(pHN)in iterative Orthogonal Frequency Division Multiplexing(OFDM)receivers used for high speed and high spectral efficient wireless communication *** MAp cost function for joint estimation and detection is derived and optimized further with the proposed cyclic gradient descent optimization *** proposed joint estimation and detection algorithm relaxes the restriction of small pHN assumptions and utilizes the prior statistical knowledge of pHN spectral components to produce a statistically optimal *** frequency-domain estimation of Channel Transfer Function(CTF)in frequency selective fading makes the method simpler,compared with the estimation of Channel Impulse response(CIr)in the time *** different time-varying pHN models,produced by Free running Oscillator(FrO)and phase-Locked Loop(pLL)oscillator,are presented and compared for performance difference with proposed OFDM *** results for joint MAp channel estimation are compared with Cramer-rao Lower Bound(CrLB),and the simulation results for joint MAp data detection are compared with“NO pHN"performance to demonstrate that the proposed joint MAp estimation and detection algorithm achieve near-optimum performance even under multipath channel fading.

关键词： Orthogonal frequency division multiplexing phase noise Free running oscillator phase-locked loop oscillator Maximum a posteriori Channel estimation Data detection

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Model-based Tracking for Agent-based Control Systems in the Case of Sensor Failures

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International Journal of Automation and computing 2012年第6期9卷 561-569页

作者： r.p.yadav p.V.Varde p.S.V.Nataraj p.Fatnani C.p.Navathe Accelerator Control Section Accelerator Control and Beam Diagnostics DivisionRaja Ramanna Centre for Advanced Technology Life Cycle reliability Engineering Lab Safety Evaluation and Manpower Training and Development SectionBhabha Atomic Research Centre Inter Disciplinary program in Systems and Control Engineering Group Indian Institute of Technology Bombay

The study on artificial intelligence(AI) methods for tuning of particle accelerators has been reported in many *** paper presents tuning method for agent-based control systems of transport lines in the case of sensor/actuator *** method uses model-based tracking concept to relax the demand on sensor *** condition for successful operation of the stated scheme is derived,and the concept is demonstrated through simulation by applying it to the model of microtron,transport line-1 and booster of indus *** results show that this approach is very effective in transport line control during sensor/actuator failures.

关键词： Agent agent-based control model-based tracking transport line control artificial intelligence(AI).

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Spastin and alsin protein interactome analyses begin to reveal key canonical pathways and suggest novel druggable targets

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Neural regeneration research 2025年第3期20卷 725-739页

作者： Benjamin r.Helmold Angela Ahrens Zachary Fitzgerald p.Hande Ozdinler Department of Neurology Feinberg School of MedicineNorthwestern UniversityChicagoILUSA Center for Molecular Innovation and Drug Discovery Center for Developmental TherapeuticsChemistry of Life Processes InstituteNorthwestern UniversityEvanstonILUSA Mesulam Center for Cognitive Neurology and Alzheimer’s Disease Feinberg School of MedicineNorthwestern UniversityChicagoILUSA Feinberg School of Medicine Les Turner ALS Center at Northwestern UniversityChicagoILUSA

Developing effective and long-term treatment strategies for rare and complex neurodegenerative diseases is challenging. One of the major roadblocks is the extensive heterogeneity among patients. This hinders understanding the underlying disease-causing mechanisms and building solutions that have implications for a broad spectrum of patients. One potential solution is to develop personalized medicine approaches based on strategies that target the most prevalent cellular events that are perturbed in patients. Especially in patients with a known genetic mutation, it may be possible to understand how these mutations contribute to problems that lead to neurodegeneration. protein–protein interaction analyses offer great advantages for revealing how proteins interact, which cellular events are primarily involved in these interactions, and how they become affected when key genes are mutated in patients. This line of investigation also suggests novel druggable targets for patients with different mutations. Here, we focus on alsin and spastin, two proteins that are identified as “causative” for amyotrophic lateral sclerosis and hereditary spastic paraplegia, respectively, when mutated. Our review analyzes the protein interactome for alsin and spastin, the canonical pathways that are primarily important for each protein domain, as well as compounds that are either Food and Drug Administration–approved or are in active clinical trials concerning the affected cellular pathways. This line of research begins to pave the way for personalized medicine approaches that are desperately needed for rare neurodegenerative diseases that are complex and heterogeneous.

关键词： ALS2 alsin amyotrophic lateral sclerosis hereditary spastic paraplegia neurodegenerative diseases personalized medicine precision medicine protein interactome protein-protein interactions SpAST spastin

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Heterogeneity of mature oligodendrocytes in the central nervous system

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Neural regeneration research 2025年第5期20卷 1336-1349页

作者： Chao Weng Adam M.r.Groh Moein Yaqubi Qiao-Ling Cui Jo Anne Stratton G.r.Wayne Moore Jack p.Antel Neuroimmunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous *** evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to *** the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is *** delve into early 20th-century studies by robertson and río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature ***,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination ***,modern molecular investigations,employing techniques such as single cell/nucleus rNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system *** and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric ***,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined *** studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte *** research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,

关键词： aging central nervous system diseases electron microscopy heterogeneity immunohistochemistry myelin sheath natural history neuroglia oligodendroglia single-cell gene expression analysis

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Experimental and Quantum Studies on Adsorption and Corrosion Inhibition Effect on Mild Steel in Hydrochloric Acid by Thiophene Derivatives

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Acta Metallurgica Sinica(English Letters) 2014年第1期27卷 37-46页

作者： M.yadav Debasis Behera r.r.Sinha p.N.yadav Department of Applied Chemistry Indian School of Mines Department of physics Post Graduate College

The inhibition effect of synthesized diethyl 3,4-bis（4-methoxybenzylideneamino） thieno[2,3-b] thiophene-2,5- dicarboxylate （Inh I） and diethyl 3,4-bis（benzylideneamino） thieno[2,3-b] thiophene-2,5-dicarboxylate （Inh II）, on cor- rosion of mild steel in 15% HC1 solution was investigated using weight loss measurements, electrochemical polarization, and electrochemical impedance spectroscopy techniques. The experimental results show that the inhibition efficiency of studied inhibitors increased with the increase of inhibitors concentration but decreased with the increase of temperature. Corrosion inhibition efficiencies of 94.5% and 92.1% were obtained with 250 ppm of Inh I and Inh II at 303 K, respectively. The potentiodynamic polarization measurements indicate that the studied inhibitors act as mixed inhibitor. The thermodynamic parameters of the corrosion and adsorption processes were calculated and evaluated. The adsorption of these inhibitors was found to obey Langmuir adsorption isotherm. Scanning electron microscopy was used to characterize the surface morphology of the mild steel specimens in presence and absence of inhibitors. The mechanism of the inhibition process was discussed in the light of the chemical structure and quantum-chemical calculations of the investigated inhibitors.

关键词： Mild steel Corrosion polarization EIS Acid inhibition

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Motion through spherical droplet with non-homogenous porous layer in spherical container

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Applied Mathematics and Mechanics(English Edition) 2020年第7期41卷 1069-1082页

作者： p.K.yadav A.TIWArI p.SINGH Department of Mathematics Motilal Nehru National Institute of Technology AllahabadPrayagraj 211004India Department of Mathematics Birla Institute of Technology SciencePilani 333031Rajasthan Department of Mathematics National Institute of Technology PatnaPatna 800005India

The problem of the creeping flow through a spherical droplet with a non-homogenous porous layer in a spherical container has been studied ***’s model for the flow inside the porous annular region and the Stokes equation for the flow inside the spherical cavity and container are used to analyze the *** drag force is exerted on the porous spherical particles enclosing a cavity,and the hydrodynamic permeability of the spherical droplet with a non-homogeneous porous layer is *** is placed on the spatially varying permeability of a porous medium,which is not covered in all the previous works related to spherical *** variation of hydrodynamic permeability and the wall effect with respect to various flow parameters are presented and discussed *** streamlines are presented to discuss the kinematics of the *** previous results for hydrodynamic permeability and drag forces have been verified as special limiting cases.

关键词： non-homogenous porous medium Stokes equation Darcy’s law perme-ability parameter wall effect

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Nonlinear parametric interactions in ion-implanted semiconductor plasmas having strain-dependent dielectric constants

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Chinese physics B 2017年第1期26卷 304-309页

作者： N yadav S Ghosh p S Malviya School of Studies in physics Vikram University Ujjain 465010 India Department of physics Govt. J.N.S. Post Graduate College Shujalpur 465333 India

We report nonlinear parametric interactions using a hydrodynamic model of ion-implanted semiconductor plasmas having strain-dependent dielectric constants（SDDC）. High-dielectric-constant materials are technologically important because of their nonlinear properties. We find that the third-order susceptibility varies in the range 10^-14--10^-12m^2·V^-2 for ion-implanted semiconductor plasmas, which is in good agreement with previous results. It is found that the presence of SDDC in ion-implanted semiconductor plasma modifies the characteristic properties of the material.

关键词： nonlinear parametric interactions ion-implanted semiconductor plasmas strain-dependent dielectric constant

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A proper motion study of the globular cluster M12(NGC 6218)

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research in Astronomy and Astrophysics 2018年第10期18卷 97-108页

作者： Devesh p.Sariya Ing-Guey Jiang r.K.S.yadav Department of physics and Institute of Astronomy National Tsing Hua UniversityHsin-Chu Aryabhatta research Institute of observational sciencES(ArIES) Manora PeakNainital 263 002India

Using astrometric techniques developed by Anderson et al., we determine proper motions （pMs） in the ~ 14.60 × 16.53 arcmin^2 area of the kinematically ＂thick-disk＂ globular cluster M 12. The cluster＇s proximity and sparse nature makes it a suitable target for ground-based telescopes. Archive images with time gap of ~ 11.1 years were observed with the wide-field imager （WFI） mosaic cam-era mounted on the ESO 2.2m telescope. The median value of pM error in both components is 0.7masyr^-1 for the stars having V ≤ 20mag. pMs are used to determine membership probabil-ities and to separate field stars from the cluster sample. In electronic form, a membership catalog of 3725 stars with precise coordinates, pMs and BVrI photometry is being provided. One of the possible applications of the catalog is demonstrated by gathering the membership information of the variable stars, blue stragglers and X-ray sources reported earlier in the cluster＇s region.

关键词： Galaxy globular clusters - astrometry - catalogs - individual M12

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Shifting paradigms for Nepal＇s protected areas： history, challenges and relationships

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Journal of Mountain Science 2017年第5期14卷 964-979页

作者： Babu r BHATTArAI Wendy WrIGHT Buddi S pOUDEL Achyut ArYAL Bhupendra p yadav radha WAGLE Department of National parks and Wildlife Conservation #860KathmanduNepal Faculty of Science and Technology Federation University AustraliaVictoriaAustralia Department of Forest research and Survey #3339KthmanduNepal Institute of Mathematical and Natural Sciences Massey University#102904AucklandNew Zealand Ministry of Forests and Soil Conservation #12476 KathmanduNepal

The modern history of protected area(pA) management in Nepal dates back to 1973 when the National parks and Wildlife Conservation Act(1973) was promulgated and Chitwan National park was established. In the years immediately following these key events, protected area acts and regulations were strictly applied and the role of local people in managing natural resources was neglected. However with the passage of time, and with changes in the socio-political and economic characteristics of Nepal, management regimes have shifted towards a more liberal model which recognizes more clearly the contributions of people living and working within protected areas. recently, landscape level conservation models including the designation of multiple use areas have been utilized in the development of management plans for protected areas in Nepal. Conservation agencies have attempted to tackle challenges such as land use conflict, poaching and smuggling of wildlife parts and illegal harvesting of highly valued medicinal herbs through regulation, but these efforts are not always successful. We recommend a holistic conflict resolution approach which recognizes and resolves the different needs of all stakeholders.

关键词： protected area National park Conservation Management Development history Nepal

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Large time asymptotics for solutions to a nonhomogeneous Burgers equation

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Applied Mathematics and Mechanics(English Edition) 2010年第9期31卷 1189-1196页

作者： S.r.CHIDELLA M.K.yadav Department of Mathematics Indian Institute of Technology Madras

In this article, the solutions to a nonhomogeneous Burgers equation subject to bounded and compactly supported initial profiles are constructed. In an interesting study, Kloosterziel （Journal of Engineering Mathematics 24, 213-236 （1990）） represented a solution to an initial value problem （IVp） for the heat equation, with an initial data in a class of rapidly decaying functions, as a series of self-similar solutions to the heat equation. This approach quickly revealed the large time behaviour for the solution to the IVp. Inspired by Kloosterziel＇s approach, the solution to the nonhomogeneous Burgers equation is expressed in terms of the self-similar solutions to the heat equation. The large time behaviour of the solutions to the nonhomogeneous Burgers equation is obtained.

关键词： nonhomogeneous Burgers equation Hermite polynomials self-similar solutions

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