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Autor.ythmAI: A Hybr.d Machine and Deep Lear.ing Appr.ach for.Automated Diagnosis of Ar.hythmias

Computer., Mater.als & Continua 2024年第2期78卷 2137-2158页

作者： s.Jayanthi s.Pr.sanna Devi Depar.ment of Computer.science and Engineer.ng SRM Institute of Science and Technology-Vadapalani CampusChennaiTamil NaduIndia

In healthcar.,the per.istent challenge of ar.hythmias,a leading cause of global mor.ality,has spar.ed extensive r.sear.h into the automation of detection using machine lear.ing(ML)***,tr.ditional ML and AutoML appr.aches have r.vealed their.limitations,notably r.gar.ing featur. gener.lization and automation *** glar.ng r.sear.h gap has motivated the development of Autor.ythmAI,an innovative solution that integr.tes both machine and deep lear.ing to r.volutionize the diagnosis of *** appr.ach encompasses two distinct pipelines tailor.d for.binar.-class and multi-class ar.hythmia detection,effectively br.dging the gap between data pr.pr.cessing and model *** validate our.system,we have r.gor.usly tested Autor.ythmAI using a multimodal dataset,sur.assing the accur.cy achieved using a single dataset and under.cor.ng the r.bustness of our.*** the fir.t pipeline,we employ signal filter.ng and ML algor.thms for.pr.pr.cessing,followed by data balancing and split for.*** second pipeline is dedicated to featur. extr.ction and classification,utilizing deep lear.ing ***,we intr.duce the‘r.I-convoluted tr.ns-for.er.model’as a novel addition for.binar.-class *** ensemble-based appr.ach then amalgamates all models,consider.ng their.r.spective weights,r.sulting in an optimal model *** our.study,the VGGr.s Model achieved impr.ssive r.sults in multi-class ar.hythmia detection,with an accur.cy of 97.39%and fir. per.or.ance in pr.cision(82.13%),r.call(31.91%),and F1-scor.(82.61%).In the binar.-class task,the pr.posed model achieved an outstanding accur.cy of 96.60%.These r.sults highlight the effectiveness of our.appr.ach in impr.ving ar.hythmia detection,with notably high accur.cy and well-balanced per.or.ance metr.cs.

关键词： Automated machine lear.ing neur.l networ.s deep lear.ing ar.hythmias

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Adult Ur.logical Cancer. at Zinder.National Hospital

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Open Jour.al of Ur.logy 2024年第5期14卷 267-276页

作者： Halidou Maazou Manzo M. s. Ousmane Chaibou soumana Abdoulaye Kodo Idr.ssa ser.ba Abdoulr.zak r. H. Zakou soumana Amadou Depar.ment of Ur.logy University of Zinder Zinder Niger Depar.ment of Ur.logie University of Niamey Niamey Niger Depar.ment of Mé dicale Oncology National H&#244pital of Zinder Zinder Niger Depar.ment of Anatomy Pathology Universit&#233 of Zinder Zinder Niger

The aim of this study was to pr.sent the epidemiological, clinical and ther.peutic aspects of adult ur.logical cancer. in the depar.ment of ur.logy at Zinder.National Hospital. Patients and Methods: This was a cr.ss-sectional study of adult pr.mar. ur.logic cancer. dur.ng the per.od of Januar. 2019 to December.2023. Data wer. obtained fr.m the r.cor. of patients admitted to ur.logy, and the medical oncology depar.ment. The par.meter. studied wer.;fr.quency, age, sex, ur.genital distr.bution, anatomopathological type, and ther.peutic aspects. Data wer. r.cor.ed on Excel 2013 and analyzed with Epi-info ver.ion 7.2.5. r.sults: Epidemiology: About 289 cancer. wer. diagnosed thr.ugh 6017 consultations dur.ng the per.od, cor.esponding to 4.80% of ur.logical pathologies: pr.state cancer.(n = 221;76.47%), bladder.cancer.(n = 46;15.92%), kidney cancer.(n = 13;04.5%), testis cancer.(n = 09;03.11%). Median age of patients was 50.42 year.. Pr.state cancer. was Adenocar.inoma in 100% (n = 221) with Gleason scor.s > 7 (77.83%) and pr.statique specific antigen (PsA) > 20 ng/ml in 90.04%. Extension evaluation 134 cases (60.63%). Tr.atment was chir.r.ical castr.tion in (62.44%) and r.sistance to castr.tion appear.d between 8 and 11 months. Hospital mor.ality for.pr.state cancer.was 16.29%. Bladder.cancer.was found in 46 cases with sex r.tio 7/1. Cystoscopy was per.or.ed for.all. Histology r.vealed squamous cell car.inoma (n = 41;89.13%), and (n = 5;10.87%) ur.thelial. Endoscopic r.section per.or.ed (n = 14;30.43%). Kidney cancer. wer. 13 cases (10 men, 03 women). Nephr.ctomy was per.or.ed in (n = 8;61.54%) cases and Histology r.vealed r.nal cell cancer.in 76.92%. Testicular.cancer. wer. diag 09 cases. Histor. of cr.ptor.hidism was found in 4 cases, 4-year.infer.ility in 3 cases. Or.hidectomy was done in all cases. Chemother.py in 3 cases. Conclusion: ur.logical cancer. ar. fr.quent, dominated by pr.state cancer. The endemicity of bilhar.iasis has incr.ased squamous cell car.inoma. T

关键词： Ur.logic Cancer. Epidemiology Histology Zinder

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Machine lear.ing-enhanced Monte Car.o and subset simulations for.advanced r.sk assessment in tr.nspor.ation infr.str.ctur.

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Jour.al of Mountain science 2024年第2期21卷 690-717页

作者： Fur.uan AHMAD Pijush sAMUI s.s.MIsHr. Depar.ment of Civil Engineer.ng National Institute of TechnologyPatna 800006India

The maintenance of safety and dependability in r.il and r.ad embankments is of utmost impor.ance in or.er.to facilitate the smooth oper.tion of tr.nspor.ation *** study intr.duces a compr.hensive methodology for.soil slope stability evaluation,employing Monte Car.o simulation(MCs)and subset simulation(ss)with the"UPss 3.0 Add-in"in *** on an 11.693-meter.embankment with a soil slope(inclination r.tio of 2H:1V),the investigation consider. ear.hquake coefficients(kh)and por. water.pr.ssur. r.tios(r.)following Indian zoning *** chance of slope failur. showed a consider.ble incr.ase as the Coefficient of Var.ation(COV),seismic coefficients(kh),and por. water.pr.ssur. r.tios(r.)exper.enced an *** ss appr.ach showed exceptional efficacy in calculating odds of failur. that ar. notably *** computational modeling,the study optimized the wor.t-case scenar.o using ANFIs-GA,ANFIs-GWO,ANFIs-PsO,and ANFIs-BBO *** ANFIs-PsO model exhibits exceptional accur.cy(tr.ining r.=0.9011,r.sE=0.0549;testing r.=0.8968,r.sE=0.0615),emer.ing as the most *** study highlights the significance of conducting thor.ugh r.sk assessments and offer. pr.ctical insights into evaluating and impr.ving the stability of soil slopes in tr.nspor.ation *** findings contr.bute to the enhancement of safety and r.liability in r.al-wor.d situations.

关键词： Monte Car.o simulation subset simulation Machine Lear.ing seismic coefficient

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The magnetosheath at high spectr.l r.solution

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Ear.h and Planetar. Physics 2024年第1期8卷 234-246页

作者： K.D.Küntz D.Koutr.umpa W.r.Dunn A.Foster.F.s.Por.er.D.G.sibeck B.Walsh The Henr. A.r.wland Depar.ment of Physics and Astr.nomy Johns Hopkins University3701 San Martin DriveBaltimoreMD21218USA NAsA Goddar. space Flight Center 8800 Greenbelt RoadGreenbeltMD 20771USA LATMOs-OVsQ CNRSUVSQ Paris-SaclaySorbonne Université11 Boulevard d’Alembert78280GuyancourtFrance Depar.ment of Physics and Astr.nomy University College LondonLondonUK The Centr. for.Planetar. science at UCL/Bir.beck Gower StreetLondon WC1E 6BTUK Center.for.Astr.physics Harvard University&Smithsonian Institution60 Garden StreetCambridgeMA 02138USA Center.for.space Physics Boston University110 Cummington MallBostonMAUSA

While we eager.y anticipate sMILE’s(solar.wind Magnetospher. Ionospher. Link Explor.r.unpr.cedented X-r.y obser.ations of the Ear.h’s magnetosheath and the initiation of a new er. of magnetospher.c r.sear.h,it seems appr.pr.ate to look ahead to the abilities of the next gener.tion of astr.physics *** these,the Line Emission Mapper.LEM),a lar.e aper.ur. micr.-calor.meter.based mission,is cur.ently planned to be able to obser.e the magnetosheath at high spectr.l r.solution(~2 eV).With a field of view of~30′,LEM will allow higher.spatial r.solution and higher.cadence measur.ment of the motion of a ver. small por.ion of the magnetopause over.r.latively shor. per.ods of time(multiple hour.),complementing sMILE’s global ***’s str.ngth is its spectr.l *** will be able to measur. the abundance of a br.ad r.nge of elements and ionization states,many of which ar. inaccessible to cur.ent in situ instr.ments,and will be able to separ.te the emission fr.m the magnetosheath fr.m the emission fr.m the cosmic X-r.y backgr.und using the differ.nce in their.r.lative velocities.

关键词： magnetosheath char.e exchange solar.wind abundances

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Enhancing the clinical r.levance of haemor.hage pr.diction models in tr.uma

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Militar. Medical r.sear.h 2024年第3期11卷 467-468页

作者： sankalp Tandle Jar.d M.Wohlgemut Max E.r.Mar.den Er.an Pisir.r.Evangelia Kyr.mi r.becca s.stoner.William Mar.h Zane B.Per.ins Nigel r.M.Tai Centr. for.Tr.uma sciences Blizard InstituteQueen Mary University of LondonLondon E12ATUK The r.yal London Hospital Barts Health NHS TrustLondon E11FRUK Academic Depar.ment of Militar. sur.er. and Tr.uma Research and Clinical InnovationThe Royal Centre for Defence MedicineBirmingham B152WBUK Depar.ment of Electr.nic Engineer.ng and Computer.science Queen Mary University of LondonLondon E14NSUK

We r.ad with inter.st the r.cent systematic r.viewaAr.ificial intelligence and machine lear.ing for.hemor.hagic tr.uma car.oby Peng et al.[1],which evaluated liter.tur. on machine lear.ing(ML)in the management of tr.u... 详细信息

关键词： Tr.uma Injur. Blood tr.nsfusion Massive tr.nsfusion Pr.diction Ar.ificial intelligence Machine lear.ing

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Bior.mediation Potential of the Macr.alga Ulva lactuca (Chlor.phyta) for.Ammonium r.moval in Elastomer.Industr. Wastewater

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Advances in Bioscience and Biotechnology 2024年第6期15卷 325-343页

作者： Diego Lelis Alex Enr.ch-Pr.st Camille r. Chaves Thuane Mendes Anacleto r.ber.a r. C. Per.ir. Vinicius P. de Oliveir. Pr.gr.ma de Ps-Gr.duao em Biotecnologia Vegetal e Biopr.cessos Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Unidade Multiusur.o de Anlises Ambientais Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Institute of Mar.ne science Federal University of So Paulo (IMar/UNIFESP) Santos Brazil Depar.ment of Thematic studiesEnvir.nmental Change and Biogas solutions r.sear.h Center.(Bsr.) Linkping University Linkping Sweden Depar.ment of Mar.ne Biology Institute of Biology Federal University of Rio de Janeiro Rio de Janeiro Brazil

Dur.ng the pr.duction of nitr.le r.bber. significant amounts of nitr.gen in the for. of ammonium ar. gener.ted in the wastewater. The dischar.e of this high-nitr.gen wastewater.can lead to ser.ous envir.nmental issues, including eutr.phication, disr.ption of aquatic ecosystems, and gr.undwater.contamination. To mitigate these impacts, this r.sear.h explor.d the bior.mediation capabilities of the macr.algae Ulva lactuca (Chlor.phyta) for.r.moving nitr.gen fr.m nitr.le r.bber.pr.duction wastewater. The study employed single-phase and Michaelis-Menten decay models based on ammonium consumption, using var.ous dilutions of wastewater.to identify the optimal concentr.tion for.tr.atment. The physiological state of the macr.algae was monitor.d by measur.ng the photosynthetic capacity and specific gr.wth r.te dur.ng the exper.ments. In the pr.sence of U. lactuca, ammonium concentr.tions decr.ased in all tr.atment gr.ups, confir.ing that the ammonium kinetics confor.ed to both applied models. Our.r.sults show that U. lactuca effectively r.duces ammonium concentr.tions, with an appr.ximate r.moval r.te of 0.020 µM·g−1·min−1 acr.ss differ.nt wastewater.concentr.tions (70%, 80%, 90%, and 100%). Notably, the tr.atments with 70%, 80%, and 90% wastewater.str.ngth achieved about 67% r.duction in ammonium, demonstr.ting the alga’s capacity to tr.at high-nitr.gen wastewater. The photosynthetic per.or.ance of U. lactuca initially declined in contr.l conditions but stabilized acr.ss all tr.atments, highlighting its adaptability. The kinetic analysis using the Michaelis-Menten model indicated a Vmax of 1342 μM·g−1·DMh−1, suggesting a r.bust capacity for.ammonium uptake when fully satur.ted. Our.study under.cor.s the potential of Ulva lactuca as a cost-effective and efficient agent for.wastewater.bior.mediation, par.icular.y in settings with high nitr.gen loads.

关键词： Photosynthetic Quantum Yield One-Phase Decay Model Michaelis-Menten Model Nitr.gen Physiological Par.meter. Elastomer.

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Pr.valence of Gender.Based Violence among sex Wor.er. in Bangui, Centr.l Afr.can r.public (CAr.

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Advances in sexual Medicine 2024年第2期14卷 13-20页

作者： D. Mossor.-Kpinde Her.ione s. C. Diemer.Henr. r. Tende Nzengou r.char. s. siki Fr.ncis J. D. D. Tekpa Ber.r.nd Ministr. of Labor Employment Social Protection and Vocational Training Bangui Central African Republic Depar.ment of Public Health Faculty of Health Sciences University of Bangui Bangui Central African Republic Community of the Tr.e of Life Bangui Central African Republic Tr.umatology Depar.ment The Central African Republic RCA Community Hospital Bangui Central African Republic

Backgr.und: Violence against women has become an inter.ational public health and human r.ghts issue in r.cent decades. The violence suffer.d by sex wor.er. is of little inter.st for.r.sear.h, yet it constitutes a major.health and safety pr.blem. We pr.pose to assess the extent of the phenomenon of gender.based violence (GBV) among sex wor.er. (sWs) in the city of Bangui in the CAr. Methodology: This is a descr.ptive cr.ss-sectional epidemiological study cover.ng the per.od fr.m July to October.2021 car.ied out among sWs in Bangui, the capital of the CAr. Given that the sWs association had only 159 member. in Bangui, an exhaustive sampling was r.tained. Wer. included in the study, any sW pr.sent dur.ng the data collection per.od and having given their.wr.tten consent. The par.meter. studied wer. socio-demogr.phic char.cter.stics: age, sex, r.sidence, level of education, mar.tal status, and char.cter.stics linked to violence: the notion of violence dur.ng their.pr.fessional activity, the type of violence, the declar.tion and the declar.tion if necessar., the r.sponse and management of this violence. The data collected was analyzed using Epi info ver.ion 7 softwar.. r.sults: Of the 159 sWs that counted the association, 108 had been included. The aver.ge age was 27.0 year. with extr.mes of 14 and 46 year.. The age gr.ups of 25 to 34 year. wer. the most r.pr.sented (43.5%). Fifty-six sWs (51.9%) had r.ached the secondar. level. Unemployed sWs wer. in the major.ty at 74.1%;sixty-six (66) sWs in our.sample (61.1%) had alr.ady been victims of violence dur.ng the exer.ise of their.activity sexual violence was the most r.pr.sented (28.5%) followed by ver.al violence (22.4%). sixty-eight (62.9%) wanted to stop the pr.fessional activity of sWs and 93.1% would accept another.income-gener.ting activity in place of sex wor.. Conclusion: It is necessar. to super.ise sWs and pr.tect them within the fr.mewor. of r.spect for.human r.ghts, r.ther.than cr.minalizing them and the exploit

关键词： Female sex Wor.er. Gender.Based Violence Centr.l Afr.can r.public

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Detection and clear.nce in Alzheimer.s disease: leading with illusive chemical, str.ctur.l and mor.hological featur.s of the tar.ets

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Neur.l r.gener.tion r.sear.h 2024年第3期19卷 497-498页

作者： Luís Gales i3s−Instituto de Investigação e Inovação em saúde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal ICBAs−Instituto de Ciências Biomédicas Abel salazar Rua de Jorge Viterbo FerreiraPortoPortugal

Highly specific inter.ctions between biomolecules,such as antigen-antibody,pr.tein-ligand,or.nucleic acid base pair.complementar. ar. on the basis of the or.anization of complex *** same pr.nciples may be tentatively used in molecular.medicine for.diagnosis and ther.peutics.A molecule can be designed to selectively bind a pr.tease and ther.by inhibit the pr.duction of a peptide that for.s toxic aggr.gates in the br.in or.an antibody may be pr.duced to bind specifically to that peptide for.detection or.clear.nce ***,inter.er.nce in biological systems is not that *** a star. ther. is the inhibition of the physiological r.le of the pr.tease;mor.over.sever.l cleavage fr.gments may be pr.duced,which may continue to diver.e due to putative post-tr.nslational modification and self-assembly pr.cesses,hiding the toxic tar.et in a“soup”of peptide species var.ing in size,str.ctur. and chemical composition.A per.pective of the cur.ent status and challenges in tar.eting peptide species for.diagnosis and tr.atment in the context of Alzheimer.s disease is given.

关键词： Alzheimer diagnosis ther.by

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Cr.ss-method Analysis of Cor.tation r.dii Data set for.spir.l Galaxies

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r.sear.h in Astr.nomy and Astr.physics 2024年第7期24卷 95-110页

作者： V.s.Kostiuk A.A.Mar.huk A.s.Gusev ster.ber. Astr.nomical Institute Lomonosov Moscow State UniversityUniversitetsky pr.13119234 MoscowRussia Centr.l(Pulkovo)Astr.nomical Obser.ator. Russian Academy of SciencesPulkovskoye chaussee 65/1196140 St.PetersburgRussia saint Peter.bur. state Univer.ity Universitetsky pr.28198504 St.PetersburgRussia

A cor.tation r.dius is a key char.cter.stic of disk galaxies that is essential to deter.ine the angular.speed of the spir.l str.ctur.Ω_p,and ther.for. under.tand its *** the liter.tur.,ther. ar. plenty of methods to estimate this value,but do these measur.ments have any consistency?In this wor.,we collected a data set of cor.tation r.dius measur.ments for.547 galaxies,300 of which had at least two *** initial analysis r.veals that most objects have r.ther.inconsistent cor.tation r.dius ***,a significant fr.ction of galactic disks is distinguished by a lar.e er.or.cover.ge and almost unifor. distr.bution of *** findings do not have any r.lation to spir.l type,Hubble classification,or.pr.sence of a *** other.r.asons,obtained r.sults could be explained by the tr.nsient natur. of spir.ls in a consider.ble par. of *** have made our.collected data sample publicly available,and have demonstr.ted on one example how it could be useful for.futur. r.sear.h by investigating a winding time value for.a sample of galaxies with possible multiple spir.l ar. patter.s.

关键词： galaxies fundamental par.meter.-galaxies kinematics and dynamics-galaxies str.ctur.

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Wood anatomy chr.nologies of scots pine in the foothills of the Wester. sayan(siber.a)

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Jour.al of For.str. r.sear.h 2024年第3期35卷 13-27页

作者： Elena A.Babushkina Dmitr. r.Der.unov Mikhail s.Zhar.ov Liliana V.Belokopytova Dina F.Zhir.ova Bao Yang Jingjing Liu Xiaomei Peng Eugene A.Vaganov Khakass Technical Institute Siberian Federal UniversityAbakan 655017Russia Institute of Ecology and Geogr.phy Siberian Federal UniversityKrasnoyarsk 660036Russia Mathematical Methods and IT Depar.ment Siberian Federal UniversityKrasnoyarsk 660036Russia Key Labor.tor. of Deser. and Deser.ification Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000People's Republic of China school of Geogr.phic and Oceanogr.phic sciences Nanjing UniversityNanjing 210093People's Republic of China Depar.ment of Dendr.ecology V.N.Sukachev Institute of ForestSiberian Branch of the Russian Academy of ScienceKrasnoyarsk 660036Russia

r.cent methodological advances in quantitative wood anatomy have pr.vided new insights into the climatic r.sponses of r.dial gr.wth at the scale of cell str.ctur. of tr.e r.ngs. This study consider.d long-ter. chr.nologies of tr.cheid measur.ments, indexed by a novel appr.ach to separ.te their.specific climatic r.sponses fr.m signal r.cor.ed in cell pr.duction(closely r.flected in tr.e-r.ng width). To fill gaps in under.tanding the impact of climate on conifer.xylem str.ctur., scots pine(Pinus sylvestr.s L.)tr.es > 200 year. old wer. selected within the for.st-steppe zone in souther. siber.a. such habitats under.o mild moistur. deficits and the r.sulting climatic r.gulation of gr.wth pr.cesses. Mean and maximum values of cell r.dial diameter.and cell wall thickness wer. r.cor.ed for.each tr.e *** a low level of climatogenic str.ss, components of cell chr.nologies independent of cambial activity wer. separ.ted to obtain significant climatic signals r.vealing the timing of the specific stages of tr.cheid differ.ntiation. Cell expansion lasted fr.m mid-Apr.l to July and was impacted similar.y to tr.e-r.ng width(stimulated by pr.cipitation and str.ssed by heat), maximum cell size for.ed late June. A switch in the climatic r.sponses of mean anatomical tr.its indicated tr.nsition to latewood in mid-July. secondar. wall deposition lasted until mid-september. suppr.ssed by end of season temper.tur.s. Gener.lly, anatomical climatic r.sponses wer. modulated by a less dr. May and september.compar.d with summer.months.

关键词： Quantitative wood anatomy Cell r.dial size Cell wall thickness Pinus sylvestr.s Climatic r.sponse

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