Adult Urological Cancers at Zinder National Hospital

作     者：Halidou Maazou Manzo M. S. Ousmane Chaibou Soumana Abdoulaye Kodo Idrissa Seriba Abdoulrazak R. H. Zakou Soumana Amadou Halidou Maazou;Manzo M. S. Ousmane;Chaibou Soumana;Abdoulaye Kodo;Idrissa Seriba;Abdoulrazak R. H. Zakou;Soumana Amadou

作者机构：Department of Urology University of Zinder Zinder Niger Department of Urologie University of Niamey Niamey Niger Department of Médicale Oncology National Hôpital of Zinder Zinder Niger Department of Anatomy Pathology Université of Zinder Zinder Niger 

出 版 物：《Open Journal of Urology》 (泌尿学期刊（英文）)

年 卷 期：2024年第14卷第5期

页      面：267-276页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Urologic Cancers Epidemiology Histology Zinder 

摘      要：The aim of this study was to present the epidemiological, clinical and therapeutic aspects of adult urological cancers in the department of urology at Zinder National Hospital. Patients and Methods: This was a cross-sectional study of adult primary urologic cancers during the period of January 2019 to December 2023. Data were obtained from the record of patients admitted to urology, and the medical oncology department. The parameters studied were;frequency, age, sex, urogenital distribution, anatomopathological type, and therapeutic aspects. Data were recorded on Excel 2013 and analyzed with Epi-info version 7.2.5. Results: Epidemiology: About 289 cancers were diagnosed through 6017 consultations during the period, corresponding to 4.80% of urological pathologies: prostate cancer (n = 221;76.47%), bladder cancer (n = 46;15.92%), kidney cancer (n = 13;04.5%), testis cancer (n = 09;03.11%). Median age of patients was 50.42 years. Prostate cancer: was Adenocarcinoma in 100% (n = 221) with Gleason scores 7 (77.83%) and prostatique specific antigen (PSA) 20 ng/ml in 90.04%. Extension evaluation 134 cases (60.63%). Treatment was chirurgical castration in (62.44%) and resistance to castration appeared between 8 and 11 months. Hospital mortality for prostate cancer was 16.29%. Bladder cancer was found in 46 cases with Sex ratio 7/1. Cystoscopy was performed for all. Histology revealed squamous cell carcinoma (n = 41;89.13%), and (n = 5;10.87%) urothelial. Endoscopic resection performed (n = 14;30.43%). Kidney cancers were 13 cases (10 men, 03 women). Nephrectomy was performed in (n = 8;61.54%) cases and Histology revealed renal cell cancer in 76.92%. Testicular cancers were diag 09 cases. History of cryptorchidism was found in 4 cases, 4-year infertility in 3 cases. Orchidectomy was done in all cases. Chemotherapy in 3 cases. Conclusion: urological cancers are frequent, dominated by prostate cancer. The endemicity of bilharziasis has increased squamous cell carcinoma. T