检索结果-南通市图书馆

冠状动脉支架内再狭窄组学生物标志物研究进展

在线全文

学校读者我要写书评

暂无评论

中国循证心血管医学杂志 2024年第4期16卷 497-500页

作者：毛天诗林谦纪翔高群潘熠万洁贾文浩北京中医药大学东直门医院心内科北京100700 北京中医药大学东方医院心内科北京100078 北京中医药大学第三附属医院心内科北京100029

随着介入心脏病学的发展,经皮冠状动脉介入治疗(PCI)已成为冠状动脉粥样硬化性心脏病(冠心病)的重要治疗手段。从金属裸支架(BMS)到新一代药物洗脱支架(DES),手术器械不断发展,血运重建的安全性和有效性得到大幅提高,但术后1年支架内再... 详细信息

随着介入心脏病学的发展,经皮冠状动脉介入治疗(PCI)已成为冠状动脉粥样硬化性心脏病(冠心病)的重要治疗手段。从金属裸支架(BMS)到新一代药物洗脱支架(DES),手术器械不断发展,血运重建的安全性和有效性得到大幅提高,但术后1年支架内再狭窄(ISR)的发生率仍有3%左右[1],严重影响患者生活质量。与新发冠状动脉(冠脉)病变相比,ISR相关的主要不良心血管事件(MACE)风险更高[2]。因此,对ISR的研究具有重要临床意义。

关键词：主要不良心血管事件介入心脏病学金属裸支架血运重建冠状动脉支架内再狭窄手术器械患者生活质量生物标志物

An Empirical Study of the Earnings Management of the Enterprises Taking Sports Industry as the Main Business： Based on USA Listed Companies

在线全文

学校读者我要写书评

暂无评论

Journal of Modern Accounting and Auditing 2013年第8期9卷 1088-1092页

作者： gao qun Huang Qian Xi'an Jiaotong University Xi'an China Xi'an Physical Education University Xi'an China

This study combines the listed companies which regard the sports industry as the main business with eamings management which is the current hot issue in the study of corporate governance at home and abroad to explore corporate governance of the enterprises taking sports industry as the main business. By summarizing and analyzing the relevant theory, the study establishes a hypothesis, designs empirical models, and verifies the hypothesis using the data of USA listed companies. Empirical results show that enterprises taking the sports industry as the main business have a higher degree of earnings management, due to the high growth potentials of this type of enterprise.

关键词： sports industry corporate governance earnings management

多源遥感数据融合及其在土地资源调查中的应用

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

干旱区资源与环境 2007年第7期21卷 35-41页

作者：高群中国科学院南京地理与湖泊研究所南京210008

多源信息融合的目的就是要充分集成不同来源数据的优点,尽可能多地获取地物信息,以大大提高解译精度和可信度。本文结合国土资源部“典型县耕地资源分布与生态退耕遥感监测”规划的前期预研究项目,利用ETM和SPOT等多源遥感数据,探讨不... 详细信息

多源信息融合的目的就是要充分集成不同来源数据的优点,尽可能多地获取地物信息,以大大提高解译精度和可信度。本文结合国土资源部“典型县耕地资源分布与生态退耕遥感监测”规划的前期预研究项目,利用ETM和SPOT等多源遥感数据,探讨不同遥感信息融合过程中的处理方法与关键技术,在对比分析所使用的各种数据优缺点的基础上,阐述了数据纠正、配准、融合的技术过程和出现的问题,列出本项目为遥感影像解译所归纳的主要地类的特征图谱。利用高分辨率遥感数据融合较低分辨率数据,进行土地利用变化分析,及时准确获取变化信息,为有关部门进行土地的规划、管理提供科学依据就有着十分重要的意义。

关键词：多源遥感数据高分辨率信息融合土地资源调查

Antibiotic resistome mostly relates to bacterial taxonomy along a suburban transmission chain

在线全文

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2022年第3期16卷 63-72页

作者： Ziyan Qin qun gao Qiang Dong Joy D.Van Nostrand Qi Qi Yifan Su Suo Liu Tianjiao Dai Jingmin Cheng Jizhong Zhou Yunfeng Yang State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China Institute of Chemical Defense Beijing 102205China Institute for Environmental Genomics and Department of Microbiology and Plant BiologyUniversity of OklahomaNormanOK 73019USA School of Civil Engineering and Environmental Sciences University of OklahomaNormanOK 73019USA Earth and Environmental Sciences Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA

Antibiotic resistance genes comprising antibiotic resistome are of great concern due to their increase in the *** evidence of shared resistomes between soils and animal husbandry has imposed potential risks to human ***,the correlation between a given community’s resistome and bacterial taxonomic composition is ***,a transmission chain of resistomes from swine manure to compost and compost-amended soil were analyzed in five suburban areas of Beijing,China,with unamended agricultural soils as control *** resistomes and bacterial taxonomic compositions were distinct between(I)manure and compost;and(II)compost-amended and control *** manure,compost,and compost-amended soils,theβ-diversity of the resistome and bacterial taxonomic composition was significantly correlated,while no correlation was detected in control *** taxonomic composition explained 36.0%of total variations of the resistome composition,much higher than environmental ***,those results demonstrated that antibiotic resistome was closely related to bacterial taxonomic composition along the suburban transmission chain.

关键词： Antibiotic resistance genes Resistome Bacterial taxonomy Transmission chain

布比卡因通过PI3K/AKT/mTOR通路对膀胱癌细胞凋亡和铁死亡的影响

在线全文

学校读者我要写书评

暂无评论

国际检验医学杂志 2024年第8期45卷 913-919页

作者：钱静李向南袁从虎吴晓丽潘高健盛如意高群南京医科大学附属盐城市第三人民医院麻醉科江苏盐城224005

目的探讨布比卡因对膀胱癌细胞凋亡和铁死亡的影响及其机制。方法常规培养人膀胱癌细胞(T24和5637)和人尿路上皮细胞(SV-HUC-1),MTT实验检测布比卡因细胞毒性,筛选合适处理浓度,将T24和5637细胞分为对照组、0.25、0.5和1 mmol/L布比... 详细信息

目的探讨布比卡因对膀胱癌细胞凋亡和铁死亡的影响及其机制。方法常规培养人膀胱癌细胞(T24和5637)和人尿路上皮细胞(SV-HUC-1),MTT实验检测布比卡因细胞毒性,筛选合适处理浓度,将T24和5637细胞分为对照组、0.25、0.5和1 mmol/L布比卡因组、布比卡因+铁死亡激动剂(Erastin)组、布比卡因+铁死亡抑制剂(Fer-1)组细胞和布比卡因+PI3K激动剂(740Y-P)组。采用流式细胞术检测细胞凋亡率,相应试剂盒检测Fe^(2+)、丙二醛(MDA)、谷胱甘肽(GSH)和活性氧(ROS)水平,Western blot检测Bcl-2、Bax、细胞色素C、xCT、GPX4和磷脂酰肌醇3/蛋白激酶B/哺乳动物雷帕霉素靶蛋白(PI3K/AKT/mTOR)相关蛋白表达。结果 0.25、0.5、1、2、4、8、16 mmol/L布比卡因均可明显抑制T24和5637细胞的活性(P<0.001),选择仅对癌细胞有毒性的0.25、0.5和1 mmol/L布比卡因进行后续研究。与对照组比较,随着布比卡因浓度增加,T24和5637细胞凋亡率、Fe^(2+)、ROS和MDA水平逐渐升高,GSH水平逐渐降低,差异有统计学意义(P<0.001);与1 mmol/L布比卡因组比较,布比卡因+Erastin组Fe^(2+)水平升高,而布比卡因+Fer-1组降低,差异有统计学意义(P<0.05)。Western blot结果显示,与对照组比较,布比卡因组细胞色素C蛋白表达增高,Bax/Bcl-2、xCT、GPX4表达,以及PI3K p85α/PI3K、p-AKT(Thr308)/AKT、p-AKT(Ser473)/AKT和p-mTOR(Ser2448)/mTOR比值降低,差异有统计学意义(P<0.001)。验证实验结果显示,与对照组比较,布比卡因+740Y-P组细胞活力和GSH水平升高,Fe^(2+)水平和细胞色素C蛋白表达降低(P<0.001)。结论布比卡因可通过抑制PI3K/AKT/mTOR信号通路激活诱导膀胱癌细胞凋亡和铁死亡。

关键词：布比卡因膀胱癌凋亡铁死亡 PI3K/AKT/mTOR信号通路

Assessing mechanisms for microbial taxa and community dynamics using process models

在线全文

学校读者我要写书评

暂无评论

mLife 2023年第3期2卷 239-252页

作者： Linwei Wu Yunfeng Yang Daliang Ning qun gao Huaqun Yin Naija Xiao Benjamin YZhou Si Chen Qiang He Jizhong Zhou Institute of Ecology Key Laboratory for Earth Surface Processes of the Ministry of EducationCollege of Urban and Environmental SciencesPeking UniversityBeijingChina Institute for Environmental Genomics University of OklahomaNormanOKUSA Department of Microbiology and Plant Biology University of OklahomaNormanOKUSA State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijingChina School of Minerals Processing and Bioengineering Central South UniversityChangshaChina Department of Mathematics Lunt HallNorthwestern UniversityEvanstonIllinoisUSA Department of Civil and Environmental Engineering The University of TennesseeKnoxvilleTennesseeUSA Institute for a Secure and Sustainable Environment The University of TennesseeKnoxvilleTennesseeUSA School of Civil Engineering and Environmental Sciences University of OklahomaNormanOklahomaUSA Earth and Environmental Sciences Lawrence Berkeley National LaboratoryBerkeleyCaliforniaUSA School of Computer Science University of OklahomaNormanOKUSA

Disentangling the assembly mechanisms controlling community composition,structure,distribution,functions,and dynamics is a central issue in *** various approaches have been proposed to examine community assembly mechanisms,quanti-tative characterization is challenging,particularly in microbial ***,we present a novel approach for quantitatively delineating community assembly mechanisms by combining the consumer–resource model with a neutral model in stochastic differential *** time-series data from anaerobic bioreactors that target microbial 16S rRNA genes,we tested the applicability of three ecological models:the consumer–resource model,the neutral model,and the combined *** results revealed that model performances varied substantially as a function of population abundance and/or process *** combined model performed best for abundant taxa in the treatment bioreactors where process conditions were *** contrast,the neutral model showed the best performance for rare *** analysis further indicated that immigration rates decreased with taxa abundance and com-petitions between taxa were strongly correlated with phylogeny,but within a certain phylogenetic distance *** determinism underlying taxa and community dynamics were quantitatively assessed,showing greater determinism in the treatment bioreactors that aligned with the subsequent abnormal system *** its mechanistic basis,the framework developed here is expected to be potentially applicable beyond microbial ecology.

关键词： community assembly mechanisms consumer-resource model neutral model species dynamics

Long-distance blue light signalling regulates phosphate deficiency-induced primary root growth inhibition

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2022年第10期15卷 1636-1637页

作者： Yi-qun gao Ling-Hua Bu Mei-Ling Han Ya-Ling Wang Zong-Yun Li Hong-Tao Liu Dai-Yin Chao 不详

(Molecular Plant 14,1539–1553;September 62021)In Figure 4G,we showed the root apical meristem lengths of different ***,because of inappropriate use of the software Adobe Illustrator(AI)and the high degree of similarity between the pictures,we mistakenly kept the picture of Col-0(panel of 50μM Pi),which was set as an object of reference in a lower layer for all the other panels for typesetting purposes and should have been deleted after typesetting,in the position of cry1cry2 mutant.A similar mistake also happened in Figure S15,in which we kept the GUS staining picture of line#3(panel of pLPR1::GUS/hy5)in the position of line#*** wrong pictures in these two figures have been substituted with correct pictures in the figure *** authors sincerely apologize for the mistakes.

关键词： Illustrator Figure deleted