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中国全科医学 2018年第36期21卷 4439-4444页

作者：冯玲周舟杨晓冬邱玉琴江西省赣州市信丰人民医院 341600 江西省赣州市第三人民医院 341000

目的阐述我国妊娠期代谢综合征的研究现状,了解我国妊娠期代谢综合征的研究趋势,为后续医疗研究提供参考。方法于2.1.-12-20系统检索中国知网,检索式为:主题="妊娠"or"代谢"or"综合征",发表时间为"1970—2.1.",检索到妊娠期代谢综合征... 详细信息

目的阐述我国妊娠期代谢综合征的研究现状,了解我国妊娠期代谢综合征的研究趋势,为后续医疗研究提供参考。方法于2.1.-12-20系统检索中国知网,检索式为:主题="妊娠"or"代谢"or"综合征",发表时间为"1970—2.1.",检索到妊娠期代谢综合征研究的相关文献569篇,对其内容进行分析。结果我国妊娠期代谢综合征研究相关文献量呈逐步增长态势,可分为初步探索、成长、成熟阶段。设置阈值(3,4,20;3,3,20;3,3,20)得出的关键词有多囊卵巢综合征、妊娠并发症、妊娠、妊娠高血压综合征。在高发文量作者中,杨慧霞、孙伟杰、杨东梓位于前列。在高发文组织机构中,北京大学第一医院妇产科、中山大学孙逸仙纪念医院妇产科、北京中医药大学、黑龙江中医药大学位于前列。结论我国妊娠期代谢综合征治疗可采用中医和西医相结合思路进行研究;作者之间、跨机构之间合作较少,研究组织机构主要集中在高校与医院,将来可扩展至社区及基层卫生医疗机构,以推动妊娠期代谢综合征研究的深入发展。

关键词：妊娠并发症多囊卵巢综合征妊娠高血压综合征 Citespace

显微根尖手术联合MTA治疗难治性慢性根尖周炎的研究

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口腔医学研究 2017年第7期33卷 770-773页

作者：邱小玲贾搏韩久松褚洪星孙书昱南方医科大学口腔医院广东省口腔医院牙体牙髓科广东广州510280 南方医科大学口腔医院广东省口腔医院口腔颌面外科广东广州510280

目的:研究在显微根尖手术治疗难治性慢性根尖周炎时应用MTA的可行性、特点、成功率及相关影响因素。方法:分析2.1.年1月~2.1.年12月间本院牙体牙髓科完成的显微根尖外科手术106例计146颗难治性慢性根尖周炎患牙的临床资料,其中上颌前牙7... 详细信息

目的:研究在显微根尖手术治疗难治性慢性根尖周炎时应用MTA的可行性、特点、成功率及相关影响因素。方法:分析2.1.年1月~2.1.年12月间本院牙体牙髓科完成的显微根尖外科手术106例计146颗难治性慢性根尖周炎患牙的临床资料,其中上颌前牙75例、下颌前牙13例、上颌前磨牙6例、下颌前磨牙4例、上颌磨牙4例、下颌磨牙4例。手术包括根尖切除、根尖倒预备、根尖倒充填主要步骤,术后1年回访,通过临床症状和放射学检查评估疗效,并对预后影响因素进行卡方检验分析。结果:显微根尖外科手术联合MTA应用的1年成功率达95.9%(140/146),根据患者性别、年龄、牙位、根尖病灶范围分别统计手术疗效,组间差异均无统计学意义。失败5例6颗患牙,主要原因为根折及合并重度牙周炎。结论:在治疗难治性慢性根尖周炎时采用显微根尖手术联合MTA应用可取得满意效果;显微根尖手术是治疗慢性根尖周炎的有效手段。

关键词： MTA(三氧化矿物凝聚体) 口腔显微镜显微根尖手术慢性根尖周炎

消化内镜医师肌肉骨骼疾患相关疼痛的现状调查分析

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工业卫生与职业病 2021年第6期47卷 452-455页

作者：仇宇悦孙喆何栩刘苓四川大学华西医院消化内科四川成都610000 四川大学华西临床医学院四川省骨科医院运动医学科治未病中心

目的了解我国消化内镜医生群体肌肉骨骼疾患(MSDs)相关疼痛的患病现状及影响因素,为改善MSDs提供参考依据。方法通过微信调查问卷形式向消化内镜医生定向发放并收集各项数据,以是否疼痛进行分组并采用SPSS 23.0分析患病的影响因素。结果... 详细信息

目的了解我国消化内镜医生群体肌肉骨骼疾患(MSDs)相关疼痛的患病现状及影响因素,为改善MSDs提供参考依据。方法通过微信调查问卷形式向消化内镜医生定向发放并收集各项数据,以是否疼痛进行分组并采用SPSS 23.0分析患病的影响因素。结果75.5%的消化内镜医医师存在肌肉骨骼疾患相关疼痛,其中表示肩部的疼痛最为严重的占41.06%,单因素分析显示疼痛与年龄、工作年限和操作数量有关;Logistic分析显示疼痛与操作数量>5000例(OR=2.007,95%CI:0.830~4.856)及>15 a工作年限(OR=2.056,95%CI:0.408~10.354)有关且差异有统计学意义(P5000例的医生患病率高达84.8%。结论我国现阶段消化内镜医师的MSDs相关疼痛现状不容忽视,亟需制定有效的预防或干预措施。

关键词：内镜医生肌肉骨骼疾患疼痛影响因素

Strong spin frustration and magnetism in kagoméantiferromagnets LnCu_(3)(OH)_(6)Br_(3)(Ln=Nd,Sm,and Eu)

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Chinese Physics B 2023年第4期32卷 103-108页

作者：钟金群余振伟岳小宇王义炎梁慧孙燕吴丹丹丁宗玲孙进孙学峰李秋菊 School of Materials Science and Engineering Anhui UniversityHefei 230601China Institute of Physical Science and Information Technology Anhui UniversityHefei 230601China department of Physics and Key Laboratory of Strongly-Coupled Quantum Matter Physics(CAS)University of Science and Technology of ChinaHefei 230026China School of Physics and Optoelectronic engineering Anhui UniversityHefei 230601China School of Optical and Electronic Information Suzhou City UniversitySuzhou 215104China

To study the effects of lanthanide ions on the geometrically frustrated antiferromagnets and their magnetic properties,we grew high-quality single crystals of LnCu_(3)(OH)_(6)Br_(3)(Ln=Nd,Sm,and Eu)by hydrothermal method and studied their crystal structures and magnetic *** refinements of the crystal structure referred to the powder x-ray diffraction data show that LnCu_(3)(OH)_(6)Br_(3)adopt a Kapellasite-type layer structure,which is isostructural to their chlorine *** susceptibilities demonstrate that LnCu_(3)(OH)_(6)Br_(3)have strong antiferromagnetic coupling and a pronounced magnetic frustration *** measurements indicate canted antiferromagnetic ordering of Cu^(2+)ions around 16 K within the kagoméplane and weak ferromagnetic ***,shoulder-like anomalies in specific heat around 16 K could be a signature of emergent of magnetic *** low-temperature negative magnetization and specific heat of LnCu_(3)(OH)_(6)Br_(3)(Ln=Nd,Sm,and Eu)indicate that Ln^(3+)ions induce more exotic magnetic ground state properties.

关键词： kagomélattice antiferromagnet single crystal spin frustration

Shanghai Score： A Prognostic and Adjuvant Treatment-evaluating System Constructed for Chinese Patients with Hepatocellular Carcinoma after Curative Resection

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Chinese Medical Journal 2017年第22期130卷 2650-2660页

作者： Hui-Chuan sun Lu Xie Xin-Rong Yang Wei Li Jian Yu Xiao-Dong Zhu Yong Xia Ti Zhang Yang Xu Bo Hu Li-Ping Du ling-Yao Zeng Jian Ouyang Wei Zhang Tian-Qiang Song Qiang Li Ying-Hong Shi Jian Zhou Shuang-Jian qiu Qian Liu Yi-Xue Li Zhao-You Tang Yu Shyr Feng Shen Jia Fan department of Liver Surgery Liver Cancer Institute Zhongshan Hospital Fudan University Key Laboratory of Carcinogenesis and Cancer Invasion Ministry of Education Shanghai 200032 China Shanghai Center for Bioinformation Technology Shanghai Academy of Science and Technology Shanghai 201203 China Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan Hubei 430074 China Key Laboratory of Computational Biology CAS-MPG Partner Institute for Computational Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200031 China department of Hepatic Surgery Eastern Hepatobiliary Surgery Hospital The Second Military Medical University Shanghai 200438 China department of Hepatobiliary Surgery Tianjin Medical University Cancer Institute and Hospital Tianjin 300040 China Center for Quantitative Sciences Vanderbilt University School of Medicine Nashville TN 37232 USA

Background： For Chinese patients with hepatocellular carcinoma （HCC）, surgical resection is the most important treatment to achieve long-term survival for patients with an early-stage tumor, and yet the prognosis after surgery is diverse. We aimed to construct a scoring system （Shanghai Score） for individualized prognosis estimation and adjuvant treatment evaluation. Methods： A multivariate Cox proportional hazards model was constructed based on 4166 HCC patients undergoing resection during 2001-2008 at Zhongshan Hospital. Age, hepatitis B surface antigen, hepatitis B e antigen, partial thromboplastin time, total bilirubin, alkaline phosphatase, y-glutamyltransferase, a-fetoprotein, tumor size, cirrhosis, vascular invasion, differentiation, encapsulation, and tumor number were finally retained by a backward step-down selection process with the Akaike information criterion. The Harrell＇s concordance index （C-index） was used to measure model performance. Shanghai Score is calculated by summing the products of the 14 variable values times each variable＇s corresponding regression coefficient. Totally 1978 patients from Zhongshan Hospital undergoing resection during 2009-2.1., 808 patients from Eastern Hepatobiliary Surgery Hospital during 2008-2.1., and 244 patients from Tianjin Medical university Cancer Hospital during 2.1.-2.1. were enrolled as external validation cohorts. Shanghai Score was also implied in evaluating adjuvant treatment choices based on propensity score matching ***： Shanghai Score showed good calibration and discrimination in postsurgical HCC patients. The bootstrap-corrected C-index （confidence interval [CI]） was 0.74 for overall survival （OS） and 0.68 for recurrence-free survival （RFS） in derivation cohort （4166 patients）, and in the three independent validation cohorts, the CIs for OS ranged 0.70 0.72 and that for RFS ranged 0.63 0.68. Furthermore, Shanghai Score provided evaluation for adjuvant treatment choices （transcatheter arteri

关键词： Adjuvant Treatment Hepatocellular Carcinoma Prognosis Shanghai Score

中国中部六省城镇居民消费水平的分析—基于2002—2.1.年面板数据的研究

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青岛科技大学学报（社会科学版） 2016年第3期32卷 31-36页

作者：谢秋玲孙冉冉刘瑀青岛科技大学计划财务处山东青岛266061

近年来,随着外贸出口的下降和国家扩大内需政策的实施,居民消费的重要性日益凸显。基于中国中部六省在2002—2.1.年间的面板数据,结合中国中部六省的消费现状,建立消费函数计量模型,并采用固定效应模型和随机效应模型进行实证分析和Haus... 详细信息

近年来,随着外贸出口的下降和国家扩大内需政策的实施,居民消费的重要性日益凸显。基于中国中部六省在2002—2.1.年间的面板数据,结合中国中部六省的消费现状,建立消费函数计量模型,并采用固定效应模型和随机效应模型进行实证分析和Hausman检验。研究发现,中国中部六省城镇居民收入、居民失业情况以及居民前一期的消费习惯对当期消费水平均存在影响。据此提出扩大中国中部地区消费的政策建议,以进一步扩大国内消费,从而使中国中部地区成为国民经济持续增长的又一引擎。

关键词：中部六省面板数据消费函数计量模型消费水平

Mortality and Morbidity of Extremely Low Birth Weight Infants in the Mainland of china： A Multi-center Study

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Chinese Medical Journal 2015年第20期128卷 2743-2750页

作者： Hui-Jia Lin Li-Zhong Du Xiao-Lu Ma Li-Ping Shi Jia-Hua Pan Xiao-Mei Tong qiu-Ping Li Jian-Guo Zhou Bing Yi ling Liu Yun-Bing Chen qiu-Fen Wei Hui-Qing Wu Mei Li Cui-Qing Li Xi-Rong Gao Shi-Wen Xia Wen-Bin Li Chao-Ying Ya ling He Kun Liang Xiao-Yu Zhou Shu-Ping Han Qin Lyu Yin-Ping qiu Wen Li Dong-Mei Chen Hong-Ru Lu Xiao-Hong Liu Hong Liu Zhen-Lang Lin Li Liu Jia-Jun Zhu Hong Xiong Shao-Jie Yue Si-Qi Zhuang department of Neonatal Intensive Care Unit Children's Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang 310053 China department of Neonatology Anhui Provincial Hospital Hefei Anhui 230001 China department of Pediatrics Peking University Third Hospital Beijing 100191 China department of Neonatology BaYi Children's Hospital of the General Military Hospital of Beijing People's Liberation Army Beijing 100000 China department of Neonatology Children's Hospital of Fudan University Shanghai 200032 China department of Neonatology Gansu Provincial Maternity and Children-care Hospital Lanzhou Gansu 730050 China department of Neonatotogy Guiyang Maternal and Child Health Care Hospital Guiyang Guizhou 550003 China department of Neonatology Women and Children Hospital of Guangdong Province Guangzhou Guangdong 510010 China department of Neonatology Guangxi Maternal and Child Health Hospital Nanning Guangxi 530003 China department of Neonatology The Third Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong 510150 China department of Neonatology Harbin Children's Hospital Harbin Heilongjiang 150010 China department of Neonatology Children's Hospital of Hebei Province Shijiazhuang Hebei 050031 China department of Neonatology Hunan Children's Hospital Changsha Hunan 410007 China department of Neonatology Hubei Maternity and Child Heath Hospital Wuhan Hubei 430070 China department of Pediatrics Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 China department of Neonatology The First Hospital of Jilin University Changchun Jilin 130021 China department of Neonatology Jiangxi Provincial Children's Hospital Nanchang Jiangxi 330006 China department of Pediatric First Affiliated Hospital of Kunming Medical University Kunming Yunnan 650032 China department of Neonatotogy Nanjing Children's Hospital of Nanjing Medical University Nanjing Jiangsu 320100 China De

Background： With the progress ofperinatal medicine and neonatal technology, more and more extremely low birth weight （ELBW） survived all over the world. This study was designed to investigate the short-term ontcomes of ELBW infants during their Neonatal Intensive Care Unit （NICU） stay in the mainland of china. Methods： All infants admitted to 26 NICUs with a birth weight （BW）〈1000 g were included between January 1,2.1. and December 31,2.1.. All the data were collected retrospectively from clinical records by a prospectively designed questionnaire. The data collected from each NICU transmitted to the main institution where the results were aggregated and analyzed. Categorical variables were performed with Pearson Chi-square test. Binary Logistic regression analysis was used to detect risk factors. Results： A total of 258 ELBW infants were admitted to 26 NICUs, of whom the mean gestational age （GA） was 28.1 ± 2.2 weeks, and the mean BW was 868 ± 97 g. The overall survival rate at discharge was 50.0%. Despite aggressive treatment 60 infants （23.3%） died and another 69 infants （26.7%） died after medical care withdrawal. Furthermore, the survival rate was significantly higher in coastal areas than inland areas （53.6% vs. 35.3%, P = 0.019）. BW 〈750 g and GA 〈28 weeks were the largest risk factors, and being small for gestational age was a protective factor related to mortality. Respiratory distress syndrome was the most common complication. The incidence of patent ductus arteriosus, intraventricular hemorrhage, periventricular leukomalacia, bronchopulmonary dysplasia, retinopathy of prematurity was 26.2%, 33.7%, 6.7%, 48.1%, and 41.4%, respectively. Ventilator associated pneumonia was the most common hospital acquired infection during hospitalization. Conclusions： Our study was the first survey that revealed the present status of ELBW infants in the mainland of china. The mortality and morbidity of ELBW infants remained high as compared to other developed countries.

关键词： Extremely Low Birth Weight Infant Mortality National Survey

基于数据挖掘研究单味与复方雷公藤制剂对类风湿关节炎贫血患者免疫、炎症、肝肾功能的影响

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中国免疫学杂志 2020年第7期36卷 804-809,814页

作者：孙艳秋刘健(指导) 忻凌文建庭董文哲方妍妍安徽中医药大学研究生院合肥230038 安徽中医药大学第一附属医院合肥230031

目的:评价单味与复方雷公藤制剂对类风湿关节炎贫血患者免疫、炎症、肝肾功能及脂代谢指标的影响。方法:收集安徽省中医院风湿病科2.1.年6月至2.1.年12月类风湿关节炎(RA)贫血患者的病历资料,依据使用的药物分为单味雷公藤(TPT)组和复... 详细信息

目的:评价单味与复方雷公藤制剂对类风湿关节炎贫血患者免疫、炎症、肝肾功能及脂代谢指标的影响。方法:收集安徽省中医院风湿病科2.1.年6月至2.1.年12月类风湿关节炎(RA)贫血患者的病历资料,依据使用的药物分为单味雷公藤(TPT)组和复方雷公藤(XFC)组,以实验室指标为基础,构建关联规则、随机行走模型来评价不同雷公藤制剂的疗效。结果:①共计1141例类风湿关节炎贫血患者符合本研究要求,其中TPT组504例,XFC组637例。②XFC组在升高RBC、Hb、HCT、MCV方面,降低RF、IgG、IgM、Anti-CCP方面优于TPT组;TPT组在降低ESR、Hs-CRP方面均优于XFC组;XFC组在肝功能AST方面、肾功能BUN方面较TPT组影响小,而TPT组在升高TG方面高于XFC组。③经关联规则发现XFC升高RBC、Hb,降低RF的支持度、置信度、提升度方面均优于TPT;而TPT组在降低Hs-CRP方面优于XFC组。④经随机行走模型分析,两组患者综合评价指标和接受的干预措施存在长程关联。两组均能改善RBC、Hb、RF、Hs-CRP指标,XFC组RBC、Hb、RF在行走正向增长率、随机波动幂率值、改善系数、期望改善值等方面均优于TPT组,而TPT组在降低Hs-CRP方面优于XFC组。结论:单味与复方雷公藤制剂均能改善RA贫血患者的免疫、炎症指标及贫血指标,但复方雷公藤在改善患者贫血程度、调节免疫反应、减少肝肾功能损伤方面优于单味雷公藤,安全性较高。

关键词：类风湿关节炎贫血雷公藤免疫炎症关联规则随机行走模型

急性呼吸窘迫综合征及呼吸支持理念:2.1.年的反思与进步

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中华重症医学电子杂志 2020年第2期6卷 120-123页

作者：潘纯孙骎邱海波刘玲东南大学附属中大医院重症医学科南京210009

急性呼吸窘迫综合征(ARDS)是临床常见的危重症,目前针对肺保护性通气及避免肺损伤的呼吸支持策略的优化仍未对ARDS患者预后产生实质的改善。2.1.年ARDS的诊断和治疗理念仍在不断的更新,主要包括对“肺开放”和“肺休息”以及神经肌肉阻... 详细信息

急性呼吸窘迫综合征(ARDS)是临床常见的危重症,目前针对肺保护性通气及避免肺损伤的呼吸支持策略的优化仍未对ARDS患者预后产生实质的改善。2.1.年ARDS的诊断和治疗理念仍在不断的更新,主要包括对“肺开放”和“肺休息”以及神经肌肉阻滞剂应用的反思、发生ARDS预测指标、机械功与ARDS患者预后及脱机模式对脱机预后的影响等。目前的进展表明ARDS临床特征及治疗反应的异质性仍被忽略,结合信息技术及大数据分析的发展,推动实现ARDS精准化治疗是未来的方向。

关键词：急性呼吸窘迫综合征肺保护性通气策略神经肌肉阻滞药通气机,机械通气机撤除法