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A novel ionic liquids grafted polysiloxane for capillary gas chromatography

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Chinese Chemical Letters 2009年第9期20卷 1111-1114页

作者： qing quan wei Mei Ling Qi Ruo Nong Fu Department of Chemistry School of Science Beijing Institute of Technology of China Beijing 100081 China

A new ionic liquids grafted polysiloxane used as stationary phase for capillary gas chromatography （CGC） is described. The stationary phase of 1-vinyl-3-hexylimidazolium hexafluorophosphate anchored to polysiloxane （PMHS-[VHIm][PF6]） was synthe- sized, characterized and coated onto capillary columns by static coating. The results show that the present stationary phase exhibits a very good chromatographic resolution and selectivity for Grob test mixture and alcohols with baseline resolution and symmetry peaks. The present work suggests that novel stationary phase has a great potential for further development and application. 2009 Mei Ling Qi. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Ionic liquids Polysiloxane Stationary phase Gas chromatography

Formation Mechanism and Binding Energy for Regular Octahedral Structure of Li_6 Cluster

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Communications in Theoretical Physics 2008年第12期50卷 1407-1410页

作者： ZHAO Yan-Ping LI Ping GOU qing-quan LIU wei-Na Institute of Atomic and Molecular Physics Sichuan University Chengdu 610065 China

The formation mechanism for the regular octahedral structure of Liscluster is proposed. The curve of the total energy versus the separation R between any two neighboring nuclei has been calculated by using the method of Gou＇s modified arrangement channel quantum mechanics （MACQM）. The result shows that the curve has a minimal energy of -44.736 89 a.u. at R = 5.07a0. When R approaches infinity, the total energy of six lithium atoms has the value of -44.568 17 a.u. So the binding energy of Li6 with respect to six lithium atoms is 0.1687 a.u. Therefore, the binding energy per atom for Li6 is 0.028 12 a.u., or 0.7637 eV, which is greater than the binding energy per atom of 0.453 eV for Li2 and the binding energy per atom of 0.494 eV for Li3 calculated in our previous work. This means that the Li6 cluster may be formed in a regular octahedral structure with a greater binding energy.

关键词： Li6 cluster formation mechanism binding energy

Dry eye and corneal sensitivity after small incision lenticule extraction and femtosecond laser-assisted in situ keratomileusis:a Meta-analysis

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International Journal of Ophthalmology(English edition) 2017年第4期10卷 632-638页

作者： Wen-Ting Cai qing-Yu Liu Cheng-Da Ren qing-quan wei Jun-Ling Liu Qian-Yi Wang Ya-Ru Du Meng-Mei He Jing Yu Department of Ophthalmology Shanghai Tenth People's Hospital Tongji University School of Medicine Shanghai 200072 China Nanchang University Nanchang 330031 Jiangxi ProvinceChina Nanjing Medical University Nanjing 210029 Jiangsu ProvinceChina

AIM：To assess the corneal sensitivity and the incidences of dry eye after small incision lenticule extraction（SMILE） and femtosecond laser-assisted in situ keratomileusis（FSLASIK）.METHODS：The Meta-analysis was performed using Rev Man *** searched on Pub Med from inception to March *** weighted mean difference（WMD） and 95% confidence intervals（CIs） were used to analyze the ***-effects or fixed-effects models were chosen up to between-study *** main outcomes were composed of the Ocular Surface Disease Index（OSDI） scores,tear film break-up time（TBUT）,Schirmer Test and corneal ***：Eight eligible studies including 772 eyes（386 in SMILE group and 386 in FS-LASIK group） were *** parameters have no significiant difference heterogeneity between SMILE and FS-LASIK group *** were significant differences between the two groups in OSDI scores at one and three months postoperatively,in TBUT at one and three months postoperatively,in corneal sensitivity at one week,about one month and three months ***,there was no significant difference observed in Schirmer Test at the follow-up ***：Compare to FS-LASIK,dry eye and the corneal sensitivity recover better in the SMILE group,in first three months after the surgery.

关键词： dry eye corneal sensation small incision lenticule extraction femtosecond laser-assisted in situ keratomileusis Meta-analysis

非工作时间的工作相关电子通讯与员工情绪耗竭和离职意向的关系机制研究

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商业经济与管理 2017年第10期 35-49页

作者：潘清泉韦慧民广西科技大学管理学院广西柳州545006 广西大学商学院广西南宁530004

非工作时间的工作相关电子通讯(WEC_NWT)作为一种边界跨越行为,包含了频率及情感基调的内涵。文章以448名员工为研究对象,实证检验了来自主管的WEC_NWT对员工情绪耗竭和离职意向的差异性影响,以及上下级关系图式(SSG)和员工工作—家庭... 详细信息

非工作时间的工作相关电子通讯(WEC_NWT)作为一种边界跨越行为,包含了频率及情感基调的内涵。文章以448名员工为研究对象,实证检验了来自主管的WEC_NWT对员工情绪耗竭和离职意向的差异性影响,以及上下级关系图式(SSG)和员工工作—家庭分割偏好特征的调节作用。结果表明,WEC_NWT频率正向影响员工情绪耗竭和离职意向;而WEC_NWT积极情感基调则负向影响情绪耗竭和离职意向。另外,SSG可以缓冲WEC_NWT频率对情绪耗竭的正向影响,即高SSG情境下,频率对情绪耗竭的正向作用相对较弱;而SSG可以强化WEC_NWT积极情感基调对情绪耗竭的负向影响,即高SSG情境下,积极情感基调对员工情绪耗竭的负向影响更强。再者,工作—家庭分割偏好强化WEC_NWT频率对情绪耗竭和离职意向的正向关系,即高分割偏好个体,WEC_NWT频率对情绪耗竭和离职意向的正向影响均更强;工作—家庭分割偏好可以部分抵销WEC_NWT积极情感基调对情绪耗竭的负向影响,即高分割偏好个体,积极情感基调对情绪耗竭的负向影响相对较弱。

关键词：非工作时间的工作相关电子通讯(WEC_NWT) 情绪耗竭离职意向上下级关系(SSG) 工作—家庭分割偏好

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting Li wei Zhang Jian Wu Hui Hong wei quan Xinyu Qiao Chun Cui Chenmeng Qiao weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

海南椰心叶甲病原菌金龟子绿僵菌的分离、鉴定及其生防潜力(英文)

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生态学报 2007年第4期27卷 1558-1564页

作者：詹儒林覃伟权宋妍张世清 H H HO 许天委黄俊生热带作物生物技术国家重点实验室中国热带农业科学院椰子研究所 Department of Biology State University of New YorkNew PalzUSA 12561

椰心叶甲[Brontispa longissima(Gestro)]是椰子的重要害虫,近年来,该虫在海南岛发生普遍,椰子受害严重。由于椰心叶甲受到自然界中某些致病微生物的侵袭,在受害的椰子树心叶上常可发现椰心叶甲僵虫,并发现大部分僵虫表面长出了霉菌,本... 详细信息

椰心叶甲[Brontispa longissima(Gestro)]是椰子的重要害虫,近年来,该虫在海南岛发生普遍,椰子受害严重。由于椰心叶甲受到自然界中某些致病微生物的侵袭,在受害的椰子树心叶上常可发现椰心叶甲僵虫,并发现大部分僵虫表面长出了霉菌,本研究的目的在于从椰心叶甲僵虫表面的霉菌中分离出绿僵菌,并对分离菌株进行鉴定和致病性测定。从僵虫表面刮下孢子或菌丝体,置于绿僵菌选择性培养基(DOA)上培养,挑出真菌菌落,经纯化后,进行生物学特性、菌落生长速率及产孢量的测定,并从PPDA、OMA、V8A和PDA中筛选菌落生长及产孢最适培养基,同时对所分离的菌株进行对椰心叶甲的致病性测定。结果表明,所有分离菌株均鉴定为金龟子绿僵菌[Metarhizium anisopliae (Metschnikoff)],PPDA是菌落生长及产孢的最适培养基,大多数菌株对椰心叶甲有较强的致病力。选取强毒菌株MA4在田间进行防治效果的初步测定,结果表明,该菌株能显著降低椰心叶甲成虫的虫口密度。这些金龟子绿僵菌菌株是首次从海南的椰心叶甲僵虫中分离到的昆虫病原真菌,该菌对海南的椰心叶甲具有很好的生防潜能。

关键词：金龟子绿僵菌分离鉴定生物防治椰心叶甲

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu wei Wan Xiuqin Rao Yue Lin Gen wei Jun Ying Fuzhou Hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

Relationship between longitudinal changes in lipid composition and ischemic stroke among hypertensive patients

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World Journal of Clinical Cases 2025年第4期13卷 18-27页

作者： Cheng-Cheng wei Yu-qing Huang Cheng-Hong Yu Department of Cardiology Tongxiang First People's HospitalTongxiang 314500Zhejiang ProvinceChina Department of Cardiology Guangdong Cardiovascular InstituteGuangzhou 510080Guangdong ProvinceChina

BACKGROUND Dyslipidemia was strongly linked to stroke,however the relationship between dyslipidemia and its components and ischemic stroke remained *** To investigate the link between longitudinal changes in lipid profiles and dyslipidemia and ischemic stroke in a hypertensive *** Between 2013 and 2014,6094 hypertension individuals were included in this,and ischemic stroke cases were documented to the end of *** changes of lipid were stratified into four groups:(1)Normal was transformed into normal group;(2)Abnormal was transformed into normal group;(3)Normal was transformed into abnormal group;and(4)Abnormal was transformed into abnormal *** examine the link between longitudinal changes in dyslipidemia along with its components and the risk of ischemic stroke,we utilized multivariate Cox proportional hazards models with hazard ratio(HR)and 95%*** The average age of the participants was 62.32 years±13.00 years,with 329 women making up 54.0%of the *** the course of a mean follow-up of 4.8 years,143 ischemic strokes *** normal was transformed into normal group was used as a reference,after full adjustments,the HR for dyslipidemia and ischemic stroke among abnormal was transformed into normal group,normal was transformed into abnormal group and abnormal was transformed into abnormal wei CC et *** changed and ischemic stroke WJCC https://*** 2 February 6,2025 Volume 13 Issue 4 group were 1.089(95%CI:0.598-1.982;P=0.779),2.369(95%CI:1.424-3.941;P<0.001)and 1.448(95%CI:1.002-2.298;P=0.047)(P for trend was 0.233),*** In individuals with hypertension,longitudinal shifts from normal to abnormal in dyslipidemia-particularly in total and low-density lipoprotein cholesterol-were significantly associated with the risk of ischemic stroke.

关键词： Longitudinal change Hypertension Dyslipidemia Lipid profile Ischemic stroke

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开关型霍尔传感器的原理与工程实现

物理实验 2003年第7期23卷 6-9页

作者：宋青权伟龙齐新元兰州铁道学院基础科学系甘肃兰州730070

介绍了开关型霍尔传感器的工作原理 ,设计了适用于工程测量的具体线路 ,并分析了该线路的特点 .

关键词：开关型霍尔传感器工作原理工程实现差动放大电路设计