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Polymorphism of CYPIAl and GSTMl genes associated with susceptibility of gastric cancer in Shandong Province of China

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World Journal of Gastroenterology 2005年第37期11卷 5757-5762页

作者： Hao li Xue-liang Chen hui-qing li the Center of Tumour Treatment Qilu Hospital of Shandong University Jinan 250012 Shandong Province China the Institute of Basic Medicine Shandong Academy of Medical Sciences Jinan 250062 Shandong Province China

AIM： To explore whether polymorphisms of the CYPIA1 and GSTM1 genes are associated with susceptibility of stomach cancer. METHODS： A total of 102 stomach cancer cases and 62 healthy persons were diagnosed by pathology in 1998- 2000 in the Qilu Hospital of Shandong University. Gene polymorphisms were detected by the PCR using sequencespecific primers. Data analysis of the case-control study was carried out using the unconditional logistic method. RESULTS： After adjustment for age, sex, educational levels, and occupation, the risk factors for stomach cancer were shown to be smoking, Helicobacter pylori （H pylon）, and presence of the CYPIM G/G and GSTM1O/O genotypes. Interaction was observed between the combined genotypes of either CYPIA1 G/G and GSTM1O/O or Hpyloriinfection, or GSTM1O/O and Hpyloriinfection or smoking. CONCLUSION： Polymorphisms of the CYPIA1 and GSTM1 genes, Hpyloriinfection and smoking are related to susceptibility to stomach cancer.

关键词： Stomach cancer CYPIA1 GSTM1 Polymorphism

Sr2+-doped rhombohedral liHf2(PO4)3 solid electrolyte for allsolid-state li-metal battery

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Rare Metals 2020年第9期39卷 1092-1098页

作者： qing-hui li Chang Xu Bing Huang Xin Yin College of Electrical and Information Engineering Hunan UniversityChangsha 410082China State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China School of Materials Science and Engineering Tianjin UniversityTianjin 300072China

Solid-state electrolytes in rechargeable all-solidstate li-metal batteries,which have better safety and higher specific capacity than conventional rechargeable liion batteries with liquid electrolytes,are limited by the low li-ion conductivity of the solid electrolyte and the large electrolyte/electrode interfacial ***,we report a new rhombohedral NAS ICON structure li1.4Sr0.2Hf1.8(PO4)3 with a high li-ion conductivity of 1.62×10-5 S·cm-1 at 25℃,and its conductivity can be improved to 3.4×10-5 S·cm-1 after the densification of the pellet by hot ***1.4Sr0.2Hf1.8(PO4)3 coated by a thin layer of polymer electrolyte showed a stable lowimpedance dendrite-free plating/stripping process in a symmetric li/li cell for 100 h;moreover,the li1.4Sr0.2Hf1.8(PO4)3 electrolyte had a small interfacial resistance in all-solid-state li/liFePO4 cell,which allows a high Coulombic efficiency and good cycling of the cell.

关键词： Solid-state electrolyte NASICON Rhombohedral phase Interfacial resistance All-solid-state battery

Formation Mechanism and Binding Energy for Body-Centred Regular Octahedral Structure of li7 Cluster

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Communications in Theoretical Physics 2007年第4X期48卷 717-720页

作者： MA Hai-Rong li Ping GOU qing-Quan li hui-li Institute of Atomic and Molecular Physics Sichuan University Chengdu 610065 China

The formation mechanism for the body-centred regular octahedral structure of li7 cluster is proposed. The curve of the total energy versus the separation R between the nucleus at the centre and nuclei at the apexes for this structure of li7 has been calculated by using the method of Gou＇s modified arrangement channel quantum mechanics （MACQM）. The result shows that the curve has a minimal energy of-52.169 73 a.u. at R = 5.06ao. When R approaches infinity, the total energy of seven lithium atoms has the value of-51.996 21 a.u. So the binding energy of li7 with respect to seven lithium atoms is 0.173 52 a.u. Therefore the binding energy per atom for li7 is 0.024 79 a.u. or 0.674 eV, which is greater than the binding energy per atom of 0.453 eV for li2, the binding energy per atom of 0.494 eV for li3 and the binding energy per atom of 0.632 eV for li5 calculated previously by us. This means that the li7 cluster may be formed stably in a body-centred regular octahedral structure with a greater binding energy.

关键词： li7 cluster formation mechanism binding energy

Hawking Radiation of Charged Particles via Tunneling from a Cylindrically Symmetric Black Hole in Anti-de Sitter Space-Time

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Communications in Theoretical Physics 2006年第4X期46卷 643-646页

作者： YANG Shu-Zheng JIANG qing-Quan li hui-ling Institute of Theoretical Physics China West Normal University Nanchong 637002 China

Applying Parikh-Wilzcek＇s semi-classical quantum tunneling model, we study the Hawking radiation of charged particles as tunneling from the event horizon of a cylindrically symmetric black hole in anti-de Sitter space-time. The derived result shows that the tunneling rate of charged particles is related to the change of Bekenstein-Hawking entropy and that the radiation spectrum is not strictly pure thermal after taking the black hole background dynamical and self-gravitation interaction into account, but is consistent with the underlying unitary theory.

关键词： cylindrically symmetric black hole Bekenstein-Hawking entropy energy conservation charge conservation tunneling rate

Fast li-ion conduction enabled by graphite fluoride flakes in solid polymer electrolyte

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Rare Metals 2023年第10期42卷 3337-3344页

作者： qing-hui li Xiao-Fen Wang Shi-Yuan Zhu qing-Dong Zhong Song-li liu Qiong-Yu Zhou School of Electrical and Information Engineering Changsha University of Science and TechnologyChangsha410114China School of Materials Science and Hydrogen Energy Foshan UniversityFoshan528000China School of Materials Science and Engineering Shanghai UniversityShanghai200444China School of Materials Science and Engineering Yangtze Normal UniversityChongqing400715China

The li-metal anode in rechargeable li-metal batteries with a high energy density suffers the side reaction with the liquid electrolytes,resulting in the associated capacity degradation and safety *** electrolytes are designed to solve the safety problems caused by dendrite growth and the limited electrochemical stability of liquid ***,a poly(ethylene oxide)(PEO)-lithium bis(trifluoromethanesulfonyl) imide(liTFSI) solid polymer electrolyte(SPE) with cost-wise.

关键词： electrolyte conduction polymer

Association of Interleukin-6-174G/C Polymorphism with the Risk of Diabetic Nephropathy in Type 2 Diabetes:A Meta-analysis

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Current Medical Science 2019年第2期39卷 250-258页

作者： Zhen-hai CUI Xiao-ting LU Kang-li XIAO Yang CHEN hui-qing li Department of Endocrinology Union HospitalTongji Medical CollegeHucizhong University of Science and TechnologyWuhan 430022China Department of Radiology Union HospitalTongji Medical CollegeHucizhong University of Science and TechnologyWuhan 430022China

Previous studies reported the association between interleukin-6(IL-6)-174G/C gene polymorphism and the risk of diabetic nephropathy in type 2 diabetes mellitus(T2DN).However,the results remain *** the present study,we conducted a meta-analysis to further examine this relationship between IL-6-174G/C gene polymorphism and *** databases(PubMed,SinoMed and ISI Web of Science)were used to search clinical case-control studies about IL-6-174G/C polymorphism and T2DN published until Apr.14,***-or random-effects n lodels were used to calculate the effect sizes of odds ratio(OR)and 95%confide nee intervals(95%CI).Moreover,subgroup analysis was performed in tenns of the excretion rate of *** the statistical analyses were con ducted using Stata 12.0.A total of 11 case-control studies were included in this study,involving 1203 cases of T2DN and 1571 cases of T2DM without *** showed that there was an association between IL-6-174G/C polymorphism and increased risk of T2DN under the allelic and recessive genetic models(G vs.C:OR=1.10,95%CI 1.03-1」&P=0.006;GG ***+GC:OR=1.11,95%CI 1.02-1.21,P=0.016).In the subgroup analysis by albuminuria,a significant association of IL-6-174G/C polymorphism with risk of T2DN was noted in the microalbuminuria group under the recessive model(OR=1.54,95%CI 1.02-2.32,P=0.038).In conclusion,this meta-analysis suggests that IL-6-174G/C gene polymorphism is associated with the risk of T2DN.

关键词： interleukin-6(IL-6)-174G/C gene polymorphism diabetic nephropathy type 2 diabetes mellitus meta-analysis

Synthesis and characterization of novel polypropylene paper releasing anion

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Chinese Chemical Letters 2009年第4期20卷 483-486页

作者： li Qiu Wang qing Shan li hui Peng Ma Xiao Feng Guo Rui Hong Wang Gang Yao College of Environmental and Chemical Engineering State Key Laboratory of Metastable Materials Science and Technology Yanshan University State Key Laboratory of Metastable Materials Science and Technology Qinhuangdao 066004 China

Polypropylene synthetic paper releasing anion was prepared from polypropylene resin, anion additives, titanium dioxide, etc., by calendar forming method. The synthetic paper was tested by anion detector, SEM, AFM, etc. Tensile strength, elongation at break, fight angle tear strength of the polypropylene synthetic paper reached the GB 13022 or QB/T1130 Standard. The synthetic paper was water and oil resistance, and released anions 10,530 cm^-3. It was environment-friendly, and a kind of good material for human＇s health.

关键词： Synthetic paper Polypropylene Functional polymer Health material Anions releasing

Synthesis for Spatially Interconnected Systems with Distributed Output Feedback Controllers

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自动化学报 2009年第8期35卷 1128-1135页

作者： HUANG Huang WU qing-He li hui Department of Automation Beijing Institute of Technology Bei- jing 100081 P.R. China

This paper considers the design of distributed control architecture for spatially interconnected systems that are composed of several similar interconnected sub-units. Each sub-unit is a linear continuous time system and directly interacts with its nearest neighbors. This class of systems exists in several applications such as automated highway systems, power systems, and computer networks. Hybrid Lyapunov criterion and the hybrid real bounded lemma are derived to determine the stability and H∞ performance of the overall system. In order to stabilize this class of systems, distributed dynamic output feedback controllers are considered, and tractable linear matrix inequality (LMI)-based algorithms for the derivation of distributed controllers are presented. The change variable approach is introduced in the LMI-based algorithms due to its higher efficiency and numerically stable implementation than the elimination algorithm as introduced in previous works. It is shown through a numerical example that the distributed H∞ controllers developed in this article are superior to decentralized controllers in several aspects.

关键词：空间互联系统自动化系统反馈控制器稳定性

Association of genetic polymorphisms of aldehyde dehydrogenase-2 with esophageal squamous cell dysplasia

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World Journal of Gastroenterology 2010年第27期16卷 3445-3449页

作者： Ying-Zhi Zhou Yu-Tao Diao Hao li hui-qing li qing Ma Jia Cui School of Economics Shandong University 27# Shanda Nanlu Jinan 250100 Shandong Province China Department of Epidemiology and Health Statistics School of Public Health 44# Wenhuaxi Road Jinan 250012 China Tumor Center Qilu Hospital of Shandong University107# Wenhuaxi RoadJinan 250012Shandong ProvinceChina Department of Epidemiology Institute of Basic MedicineShandong Academy of Medical Sciences18877# Jingshi RoadJinan 250062Shandong ProvinceChina

AIM:To demonstrate the possible associations between genetic polymorphisms of aldehyde dehydrogenase-2(ALDH2) and esophageal squamous cell dysplasia(ESCD).METHODS:All participants came from an area of high incidence of esophageal cancer and underwent an endoscopic staining examination;biopsies were taken from a non-staining area of the mucosa and diagnosed by *** on the examinations,the subjects were divided into the control group with normal esophageal squamous epithelial cells and the ESCD ***2 genotypes of 396 cases were determined including 184 ESCD cases and 212 *** odds ratio(OR) and 95% confidence intervals(95% CI) were calculated by binary logistic regression ***:The distribution of ALDH2 genotypes showed significant differences between the two *** adjustment factors were gender and age in the logistic regression *** with 2*2/2*2 genotype,2*1/2*1 genotype was found to be a risk factor for ESCD,and the OR(95% CI) was 4.50(2.21-9.19).There were significant correlations between ALDH2 genotypes and alcohol drinking/smoking/history of esophageal ***:The ALDH2 polymorphism is significantly associated with ESCD.

关键词： Aldehyde dehydrogenase 2 Polymorphism Alcohol Smoking Esophageal squamous cell dysplasia History of esophageal cancer