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Gastric cancer stem cells in gastric carcinogenesis,progression,prevention and treatment

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World Journal of Gastroenterology 2014年第18期20卷 5420-5426页

作者： Kang Li zeng Dan Yu-qiang Nie Department of Gastroenterology People’s Hospital of Tibet Autonomous Region Department of Gastroenterology Guangzhou First People’s HospitalGuangzhou Medical University

In recent decades,the study of the mechanism of tumorigenesis has brought much progress to cancer ***,cancer stem cell(CSC)theory has changed previous views of tumors,and has provided a new method for treatment of *** discovery of CSCs and their characteristics have contributed to understanding the molecular mechanism of tumor genesis and development,resulting in a new effective strategy for cancer *** CSCs(GCSCs)are the basis for the onset of gastric *** may be derived from gastric stem cells in gastric tissues,or bone marrow mesenchymal stem *** with other stem cells,GCSCs highly express drug-resistance genes such as aldehyde dehydrogenase and multidrug resistance,which are resistant to chemotherapy and thus form the basis of drug *** specific molecular markers such as CD44 and CD133 have been used for identification and isolation of GCSCs,diagnosis and grading of gastric cancer,and research on GCSC-targeted therapy for gastric ***,discussion of the recent development and advancements in GCSCs will be helpful for providing novel insight into gastric cancer treatment.

关键词： Cancer stem cells Gastric cancer Drug resistance Cancer treatment Molecular mechanism

MEASUREMENT OF THE NUCLEAR SPIN RELAXATION OF ^(131)Xe IN ^(87)Rb ATOMS

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Chinese Physics Letters 1990年第9期7卷 388-390页

作者： LIU Zidong SUN Xianping zeng Xizhi HE qiang Wuhan Institute of Physics Academia SinicaWuhan 430071

131Xe nuclear spin relaxation rate as a function of cell temperature and buffer gas pressure has been measured by Faraday rotation *** results show that spin exchange rate of 131Xe with 87Rb is C=1.68 ×10^(-21) m^(3)s^(-1),Breit-Rabi parameter is X=4.4,and rate constant for three body formation of Van der Waals molecules is Z=5.1× 10^(-44)m^(6) s^(-1).

关键词： method. relaxation rotation

Use of Spent Mushroom Substrate as Growing Media for Tomato and Cucumber Seedlings

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Pedosphere 2012年第3期22卷 333-342页

作者： ZHANG Run-Hua DUAN zeng-qiang LI Zhi-Guo State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008(China) Wuhan Vegetable Research Institute Wuhan 430065(China) Key Laboratory of Aquatic Botany and Watershed Ecology Wuhan Botanical GardenChinese Academy of SciencesWuhan 430074(China)

The aim of this research was to evaluate weathered spent mushroom substrate （SMS）, made from spent Flammulina velutipes mushroom substrate, as a growing medium for nursery seedlings. Two vegetable species, cucumber （Cucumis sativus L. cv. Jinchun No. 2） and tomato （Solanurn lycopersicum L. cv. Mandy）, were grown in 8 media of SMS in various ratios with perlite or vermiculite. A mixed substrate of peat with perlite （1：1; v：v） was used as the control （CK）. The experiment was arranged in a completely randomized design under greenhouse conditions. Prior to sowing, some physical and chemical properties of the growing media were determined. Results showed that all the mixtures had desirable physical and chemical properties for their use in nursery tomato and cucumber seedlings except for the T4 （SMS：vermiculite = 1：1; v：v） and the T8 （SMS：perlite = 2：1; v：v） mixtures. Compared with the CK, increased plant height, leaf area, fresh weight, dry weight and index of seedling quality were found in the T3 （SMS：vermiculite = 2：1; v：v） and T6 （SMS：perlite = 4：1; v：v） growing media. SMS should be considered as an alternative for the widely used but expensive and resource-limited peat in greenhouse cultivation.

关键词： mushroom substrnte nursery seedlings peat perlite vermiculite

Inverted Organic Solar Cells with Improved Performance using Varied Cathode Buffer Layers

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Chinese Journal of Chemical Physics 2012年第5期25卷 625-630,I0004页

作者： Zhi-qiang Guan Jun-sheng Yu Yue Zang Xing-xin zeng State Key Laboratory of Electronic Thin Films and Integrated Devices School of Optoelectronic Infor-mationUniversity of Electronic Science and Technology of ChinaChengdu 510054China

Organic solar cells with inverted planar heterojunction structure based on subphthalocya- nine and C60 were fabricated using several kinds of materials as cathode buffer layer （CBL）, including tris-8-hydroxy-quinolinato aluminum （Alq3）, bathophenanthroline （Bphen）, bathocuproine, 2,3,8,9,14,15-hexakis-dodecyl-sulfanyl-5,6,11,12,17,18-hexaazatrinaphthylene （HATNA）, and an inorganic compound of Cs2CO3. The influence of the lowest unoccupied molecular orbital level and the electron mobility of organic CBL on the solar cells perfor- mance was compared. The results showed that Alq3, Bphen, and HATNA could significantly improve the device performance. The highest efficiency was obtained from device with an- nealed HATNA as CBL and increased for more than 7 times compared with device without CBL. Furthermore~ the simulation results with space charge-limited current theory indicated that the Schottky barrier at the organic/electrode interface in inverted OSC structure was reduced for 27% by inserting HATNA CBL.

关键词： Organic solar cell Inverted structure Subphthalocyanine/C60 Cathode bufferlayer Space charge-limited current theory

Best bounds on the distance between 3-direction quartic box spline surface and its control net

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Applied Mathematics(A Journal of Chinese Universities) 2013年第2期28卷 147-157页

作者： zeng Xiao-ming ZHOU Guo-rong YANG Lian-qiang Department of Mathematics Xiamen University School of Mathematics Anhui University

We present the best bounds on the distance between 3-direction quartic box spline surface patch and its control net by means of analysis and computing for the basis functions of 3-direction quartic box spline *** the local bounds and the global bounds are given by the maximum norm of the first differences or second differences or mixed differences of the control points of the surface patch.

关键词： Box spline bound parametric surface basis function differences of control point.

Verification analysis of self-verifying automata via semi-tensor product of matrices

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The Journal of China Universities of Posts and Telecommunications 2014年第4期21卷 96-104页

作者： YAN Yong-yi CHEN zeng-qiang LIU Zhong-xin College of Computer and Control Engineering Nankai University College of Science Civil Aviation University of China

The semi-tensor product （STP） of matrices was used in the article, as a new matrix analysis tool, to investigate the problem of verification of self-verifying automata （SVA）. SVA is a special variant of finite automata which is essential to nondeterministic communication with a limited number of advice bits. The status, input and output symbols are expressed in vector forms, the dynamic behaviour of SVA is modelled as matrix product is STP. By such algebraic formulation, three an algebraic equation of the states and inputs, in which the necessary and sufficient conditions are presented for the verification problem, by which three algorithms are established to find out all the strings which are accepted, rejected, or unrecognized by a SVA. Testing examples show the correctness of the results.

关键词： SVA recognition power matrix approach STP matrices

Evolution Behavior of γ-Al_(3.5)FeSi in Mg Melt and a Separation Method of Fe from Al–Si–Fe Alloys

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Acta Metallurgica Sinica(English Letters) 2018年第1期31卷 48-54页

作者： Tong Gao zeng-qiang Li Yao-Xian Zhang Xiang-Fa Liu Key Laboratory for Liquid–Solid Structural Evolution and Processing of Materials Ministry of Education Shandong University

The recycling of high Fe-content Al-Si alloys is a green industry. Eliminating the harmful effect of Fe, achieving the separation of Al and Fe is one of the key problems. Different from traditional methods for iron removal, a novel method using magnesium melt to separate Al and Fe is proposed. By introducing Al-14Si-5Fe alloy into Mg melt, it was found that the γ-Al3.5FeSi phase evolves to Al3SiFe3.5 and Al5Fe2 through the melting and solidification process. Compared with the primary Al-rich γ-Al3.5FeSi phase, the formation of Fe-rich A13SiFe3.5 is quite beneficial for the separation of Al and Fe. Mg-Si-Al and Mg-Si-Fe alloys can be obtained at the top and bottom of the cooled ingot, respectively. The results in this study provide meaningful suggestions for recycling scrap Al-Si-Fe materials.

关键词： Al-Si-Fe Mg melt Fe-rich phase evolution Separation

Fast nuclide identification based on a sequential Bayesian method

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Nuclear Science and Techniques 2021年第12期32卷 116-127页

作者： Xiao-Zhe Li Qing-Xian Zhang He-Yi Tan Zhi-qiang Cheng Liang-Quan Ge Guo-qiang zeng Wan-Chang Lai Chengdu University of Technology The College of Nuclear Technology and Automation EngineeringChengdu 610059China

The rapid identification of radioactive substances in public areas is ***,traditional nuclide identification methods only consider information regarding the full energy peaks of the gamma-ray spectrum and require long recording times,which lead to long response *** this paper,a novel identification method using the event mode sequence(EMS)information of target radionuclides is *** EMS of a target radionuclide and natural background radiation were established as two different probabilistic models and a decision function based on Bayesian inference and sequential testing was *** proposed detection scheme individually processes each *** a photon is detected and accepted,the corresponding posterior probability distribution parameters are estimated using Bayesian inference and the decision function is ***,value of the decision function is compared to preset detection thresholds to obtain a detection ***ments on different target radionuclides(137Cs and 60Co)were *** count rates of the regions of interest(ROI)in the backgrounds between[651,671],[1154,1186],and[1310,1350]keV were 2.35,5.14,and 0.57 CPS,*** experimental results demonstrate that the average detection time was 6.0 s for 60Co(with an activity of 80400 Bq)at a distance of 60 cm from the *** average detection time was 7 s for 137Cs(with an activity of 131000 Bq)at a distance of 90 cm from the *** results demonstrate that the proposed method can detect radioactive substances with low activity.

关键词： Natural radiation Nuclide identification Sequential testing Nuclear safety

Analog rise-time discriminator for CdZnTe detector

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Nuclear Science and Techniques 2017年第4期28卷 59-65页

作者： Chuan-Hao Hu Guo-qiang zeng Liang-Quan Ge Shi-Long Wei Jian Yang qiang Li Hong-Zhi Li Chengdu University of Technology Chengdu 610059 China National Ocean Technology Center Tianjin 300112 China

Due to variable time for charge collection,energy resolution of nuclear detectors declines,especially compound semiconductor detectors like cadmium zinc telluride(CdZnTe) *** solve this problem,an analog rise-time discriminator based on charge comparison principle is *** reference charge signal after attenuation is compared with the deconvoluted and delayed current *** is found that the amplitude of delayed current signal is higher than that of the reference charge signal when rise time of the input signal is shorter than the discrimination time,thus generating gating signal and triggering DMCA(digital multi-channel analyzer) to receive the total integral charge *** rise time of the input signal is longer than discrimination time,DMCA remains inactivated and the corresponding total integral charge signal is *** results show that combination of the designed rise-time discriminator and DMCA can reduce hole tailing of CdZnTe detector *** resolution of the system is 0.98%@662 keV,and it is still excellent under high counting rates.

关键词： Analog rise-time discriminator CdZnTe detector Charge comparison principle