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Chinese Journal of Polymer Science 2020年第2期38卷 118-125,I0005页

作者： Meng Jin Zhao-Chen Zhu Qiu-Yan liao qian-qian li Zhen li Department of Chemistry Sauvage Center for Molecular SciencesWuhan UniversityWuhan 430072China Institute of Molecular Aggregation Science Tianjin UniversityTianjin 300072China

In this study,two new dendronized nonlinear optical(NLO)polymers were synthesized with high FTC chromophore loading density by introduction of high generation chromophore dendrons on the side *** to their suitable molecular weights,both of them possessed good solubility in common *** also inherited the advantages of dendrimers(large NLO coefficient),especially for PG2 whose NLO coefficient d33 value was as high as 282 pm·V^–***,PG2 had a good temporal stability with 80%of its maximum value being retained at the temperature as high as 129℃.

关键词： Second-order nonlinear optics Dendronized polymers Chromophore

Crab lice infestation in unilateral eyelashes and adjacent eyelids: A case report

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World Journal of Clinical Cases 2021年第33期9卷 10323-10327页

作者： Wei Tang qian-qian li Department of Ophthalmology The Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical UniversityAffiliated Wuxi Clinical College of Nantong UniversityWuxi 214000Jiangsu ProvinceChina Intensive Care Unit The Affiliated Wuxi No.2 People’s Hospital of Nanjing Medical UniversityAffiliated Wuxi Clinical College of Nantong UniversityWuxi 214000Jiangsu ProvinceChina

BACKGROUND Crab lice(Phthirus pubis)infestation can occur at any age,to either males or females,and across all regions of the ***,cases involving the eyelashes and adjacent eyelids(phthiriasis palpebrarum)are *** occurring as a sexually transmitted disease,crab lice can be spread by poor hygiene or in a dirty environment through direct contact with contaminated skin(hands)or textiles(towels and clothing).CASE SUMMARY A 50-year-old woman presented to our hospital with a 2-wk history of chronic eyelid pain and itching in the right eye,which exacerbated in the evening hours and which had not resolved following a 1-wk course of antibiotics and corticosteroid ointments(for blepharitis diagnosis from another hospital).A careful ophthalmic slit-lamp and light microscope examination revealed multiple crab lice and nits on the right upper eyelashes;the right and left lower eyelashes were *** the new diagnosis of phthiriasis palpebrarum,the patient was treated by removing the affected eyelashes,the crab lice,and their nits ***,the eyelids were washed once with povidone-iodine.A follow-up examination at 2 wk later showed complete resolution of symptoms and no evidence of *** This case emphasizes the importance of correct diagnosis and complete removal of eyelashes,crab lice and nits to cure phthiriasis palpebrarum.

关键词： Crab lice Infestation Unilateral eyelashes Phthiriasis palpebrarum Treatment Case report

Graphitic carbon nitride loaded with bismuth nanoparticles displays antibacterial photocatalytic activity

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Rare Metals 2022年第5期41卷 1570-1582页

作者： Hui Zhang ling li qian-qian li Tao Ma Jia-Qi Gao Jin-Bo Xue Shuang Gao Department of Plastic Surgery Second Hospital of Shanxi Medical UniversityTaiyuan 030001China Key Laboratory of Interface Science and Engineering in Advanced Materials Taiyuan University of TechnologyMinistry of EducationTaiyuan 030024China Department of Materials and Earth Sciences Technical University of DarmstadtDarmstadt 64287Germany

Metal-free graphitic carbon nitride nanomaterials have been widely applied in the medical antibacterial field owing to their high anisotropy, excellent stability,satisfactory biocompatibility, and non-toxicity. Herein, Bi/C_(3)N_(4) nanocomposites were successfully constructed by hydrothermal method followed by loading bismuth on the surface of graphite carbon nitride. Bi nanospheres were tightly combined with the layered g-C_(3)N_(4) surface to promote effective separation of photo-induced charges, which results in the Bi/C_(3)N_(4) composite material that exhibited excellent photocatalytic activity under visible light. In addition, the surface plasmon resonance characteristics of semi-metal Bi further enhanced the visible-light absorption of the Bi/C_(3)N_(4). However, excessive Bi may inhibit the light-trapping ability of Bi/C_(3)N_(4).1.0% Bi/C_(3)N_(4) demonstrates excellent bactericidal efficiency as high as 96.4% against Escherichia coli(E. coli), which is attributed to the promotion of the production of reactive oxidative *** enhanced mechanism of Bi/C_(3)N_(4) synergistically achieving enhanced photocatalytic antibacterial activity under the coupling of multiple advantages was clarified,providing theoretical guidance for its application in the field of water disinfection and antibacterial treatment.

关键词： Carbon nitride Bi nanospheres Schottky barrier ROS Photocatalytic antibacterial

Tau Protein Associated Inhibitors in Alzheimer Disease

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Chinese Journal of Chemistry 2014年第10期32卷 964-968页

作者： qian-qian li Ting-Ting Chu Yong-Xiang Chen Yan-Mei li Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology(Ministry of Education) Department of ChemistryTsinghua UniversityBeijing 100084China Beijing Institute for Brain Disorders Beijing 100069China

Neurofibrillary tangles composed of tau protein and senile plaque accumulated by amyloid-β(Aβ)are two hallmarks in Alzheimer disease(AD).In the patients with AD,tau is abnormally hyperphosphorylated,mutated or misfolding,which endows tau with stronger tendency to *** protein has the potency to mediate neuron toxicity of Aβ.The reduction of tau level ameliorates degeneration of neuron ***,many researches are exploring new methods to regulate tau *** review will mainly focus on small molecules that can directly inhibit tau fibrillation or control tau accumulation by regulating tau phosphorylation process.

关键词： tau protein post-translational modification Alzheimer disease aggregation inhibitors

Portal hypertension in a patient with biliary hamartomas: A case report

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World Journal of Clinical Cases 2020年第9期8卷 1745-1751页

作者： qian-qian li Xiao-Zhong Guo Hong-Yu li Xing-Shun Qi Department of Gastroenterology General Hospital of Northern Theater CommandShenyang 110840Liaoning ProvinceChina Postgraduate College Dalian Medical UniversityDalian 116044Liaoning ProvinceChina

BACKGROUND Biliary hamartomas(BH)are a rare benign disease caused by malformation of the intrahepatic bile *** are occasionally diagnosed,but often lack obvious clinical *** are usually diagnosed by biopsy and imaging tests in clinical *** studies have reported the association of BH with portal *** SUMMARY A 40-year-old man was repeatedly admitted to our hospital due to *** source of bleeding was considered to be gastroesophageal varices and portal hypertensive gastropathy by *** had no history of hepatitis virus infection,alcohol abuse,drug-induced liver injury,or autoimmune liver *** underwent magnetic resonance imaging,which showed rounded,irregular,low-signal-T1 and high-signal-T2 lesions diffusely distributed on the liver,that were not communicated with the biliary system on magnetic resonance *** to the imaging examination,the patient was considered to have a diagnosis of BH with portal *** Based on the present case report,BH may be a potential etiology of portal hypertension.

关键词： Biliary hamartomas Portal hypertension Variceal bleeding Computed tomography Magnetic resonance imaging Case report

Sucrose as chiral selector for determining enantiomeric composition of phenylalanine by UV-vis spectroscopy and chemometrics

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Chinese Chemical Letters 2012年第9期23卷 1055-1058页

作者： qian qian li Jia Duan li Jun Wu Yue Huang Guo Tang Shun Geng Min College of Science China Agricultural UniversityChina Beijing 100193

The determination of enantiomeric composition by partial least squares （PLS） modeling of UV-vis spectral data was investigated for samples of phenylalanine （phe） using sucrose as a chiral auxiliary. And a new data preprocess method, reference band normalization, was introduced to eliminate the spectral variations due to the changes of total concentration of phe. The determination coefficient （R2） and the standard error of calibration set （SEC） of 13 standard samples are 0.9987 and 0.0128 respectively. The standard error of validation set （SECV） of 7 validation samples is 0.0049. The standard error of predict （SEP） of 6 blind samples for evaluating the robustness of the model is 0.0366. The regression model is robust to determine enantiomeric composition when total concentration varied. It is demonstrated that the reference band normalization is a convenient method of compensating for variations in total concentrations without knowing that in advance.

关键词： Chiral analysis Partial least squares Sucrose Enantiomer Phenylalanine

Medical assistance in fighting against COVID-19 in Wuhan,China:A frontline nurse’s experience and lessons learned

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Journal of Integrative Nursing 2020年第2期2卷 85-88页

作者： qian‑qian li Feng‑li GAO Division of Nursing Beijing Chao‑Yang HospitalCapital Medical UniversityBeijingChina

This article shared personal experiences of encountering challenges during the work at the frontline fighting against COVID-19 in Wuhan,China,and found solutions and suggestions to overcome the challenges during the period,including solutions to address challenges encountered during work,suggestions for smooth communication among different parties,and suggestions for optimizing work regulations and workflow and establishing behavior habits and professional knowledge and *** experiences would be helpful for health‑care workers to fight against the pandemic.

关键词： COVID‑19 experiences health‑care worker infection control medical assistance

Selection of right-circular-polarized harmonics from p orbital of neon atom by two-color bicircular laser fields

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Chinese Physics B 2019年第10期28卷 315-320页

作者： Chang-Long Xia Yue-Yue Lan qian-qian li Xiang-Yang Miao College of Physics and Information Engineering Shanxi Normal UniversityLinfen 041004China Key Laboratory of Spectral Measurement and Analysis of Shanxi Province Shanxi Normal UniversityLinfen 041004China

The polarization properties of high-order harmonic generation(HHG) in the two-color circularly polarized laser fields are investigated by numerically solving the two-dimensional time-dependent Schr?dinger equation. By adding a wavelength of 1600-nm right-circular-polarized field to an 800-nm left-circular-polarized field, HHG is simulated from a real model of neon atom with p orbital, but not from a hydrogen-like atom model with s orbital. The orders of 3n + 1 can be selected while the orders of 3n + 2 are suppressed by adjusting the intensities of the two pulses. The physical mechanism is analyzed by time-frequency analysis and semiclassical model.

关键词： high-order harmonic generation circular polarization field polarization selection

Magnetic properties and special morphology of barium ferrite via electrospinning

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Rare Metals 2017年第2期36卷 113-117页

作者： Gui-Fang liu Run-Hua Fan Zi-Dong Zhang Jing li Min Chen qian-qian li Lu Lu Pei-Tao Xie Key Laboratory for liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationShandong UniversityJinan 250061China

Barium ferrite micro-/nanofibers with special morphology,nanowires with diameters of 100 nm,nanoribbons with diameters of 1μm,and nanotubes with outer diameter of about 300 nm while inner diameter of 100 nm were successfully prepared via electrospinning using different solvents（dimethyl formamide（DMF）,solutions of deionized water and ethyl alcohol,and solutions of deionized water and acetic acid,respectively）.The barium ferrite micro-/nanofibers were characterized by scanning electron microscope（SEM）,X-ray diffraction analysis（XRD）,and vibration sample magnetometer（VSM）.The results demonstrate that the pure BaFe12O19 ferrite phase is successfully *** the SEM results show excellent *** magnetic hysteresis loops demonstrate that their magnetic properties are quite different with different *** specific saturation magnetization is approximately the same（46.12-49.17 A·m^2·kg^-1）,but the coercivity of the BaFe12O19 increases from wires（190.08 kA·m^-1）,ribbons（224.16 kA·m^-1） to tubes（258.88 kA·m^-1）.

关键词： Electrostatic spinning Barium ferrite Hollow fiber Ribbon fiber

Esophageal collateral veins in predicting esophageal variceal recurrence and rebleeding after endoscopic treatment:a systematic review and meta-analysis

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Gastroenterology Report 2020年第5期8卷 355-361,I0001,I0002页

作者： qian-qian li Hong-Yu li Zhao-Hui Bai Cyriac Abby Philips Xiao-Zhong Guo Xing-Shun Qi Department of Gastroenterology General Hospital of Northern Theater CommandShenyangLiaoningP.R.China Postgraduate College Dalian Medical UniversityDalianLiaoningP.R.China Postgraduate College Shenyang Pharmaceutical UniversityShenyangLiaoningChina The liver Unit and Monarch liver Lab Cochin Gastroenterology GroupErnakulam Medical CenterKochiIndia

Background:Endoscopic treatment is recommended for the management of esophageal ***,variceal recurrence or rebleeding is common after endoscopic variceal *** study aimed to systematically evaluate the prevalence of esophageal collateral veins(ECVs)and the association of ECVs with recurrence of esophageal varices or rebleeding from esophageal varices after endoscopic ***:We searched the relevant literature through the PubMed,EMBASE,and Cochrane library *** of paraesophageal veins(para-EVs),periesophageal veins(peri-EVs),and perforating veins(PVs)were *** ratio(RR)and odds ratio(OR)with 95%confidence intervals(CIs)were calculated for cohort studies and case-control studies,respectively.A random-effects model was *** among studies was ***:Among the 532 retrieved papers,28 were *** pooled prevalence of para-EVs,peri-EVs,and PVs in patients with esophageal varices was 73%,88%,and 54%,*** pooled prevalence of para-EVs and PVs in patients with recurrence of esophageal varices was 87%and 62%,*** risk for recurrence of esophageal varices was significantly increased in patients with PVs(OR=9.79,95%CI:1.95-49.22,P=0.006 for eight case-control studies),but not in those with para-EVs(OR=4.26,95%CI:0.38-38.35,P=0.24 for four case-control studies;RR=1.81,95%CI:0.83-3.97,P=0.14 for three cohort studies).Patients with para-EVs had a significantly higher incidence of rebleeding from esophageal varices(RR=13.00,95%CI:2.43-69.56,P=0.003 for two cohort studies).Statistically significant heterogeneity was notable across the ***:ECVs are common in patients with esophageal *** of ECVs could be helpful for predicting the recurrence of esophageal varices or rebleeding from esophageal varices after endoscopic treatment.

关键词： esophageal collateral veins esophageal varices prevalence rebleeding