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Stroke in COVID-19: a single-centre initial experience in a hotspot of the pandemic

Stroke & Vascular Neurology 2020年第4期5卷 331-336页

作者： Ivo Bach Pratibha Surathi Nora Montealegre Osama Abu-Hadid Sara Rubenstein Sviatoslav Redko Siddharth Gupta Machteld Hillen Pratit Patel priyank khandelwal Adham Kamel Department of Neurology and Neurosciences New Jersey Medical SchoolNewarkNew JerseyUSA Department of Neurological Surgery New Jersey Medical SchoolNewarkNew JerseyUSA

Background COVID-19,caused by SARS-CoV-2,is a global pandemic that has been an immense burden on healthcare systems all over the *** patients may be at higher risk for acute ischaemic stroke(AIS).We present our experience with AIS in patients with *** We reviewed all patients admitted to our hospital during a 6-week period with a positive nasopharyngeal swab test for *** these patients,we identified *** reviewed the demographics,clinical,laboratory,imaging characteristics,treatments received and outcomes of AIS in patients with *** We identified 683 patients admitted with COVID-19 during the study period,of which 20 patients had ***-vessel occlusion(LVO)was noted in 11 patients(55%).Intravenous alteplase was administered in four patients(20%)and mechanical thrombectomy was performed in five patients(25%).Respiratory symptoms preceded the onset of AIS in most of the patients(70%)by 1 to 21 *** in patients with AIS was 50%compared with 26%of all COVID-19 *** of these patients died due to non-neurological causes(70%).Three patients with AIS had clinical and imaging findings consistent with COVID-19,but were negative for multiple nasopharyngeal swab *** LVO was more common in patients with AIS and *** had more severe disease and higher mortality *** of the patients had respiratory symptoms preceding AIS by days to *** could explain certain patients with clinical picture of COVID-19 but negative nasopharyngeal swab tests.

关键词： admitted nasopharyngeal acute

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