Stroke in COVID-19: a single-centre initial experience in a hotspot of the pandemic
作者机构：Department of Neurology and NeurosciencesNew Jersey Medical SchoolNewarkNew JerseyUSA Department of Neurological SurgeryNew Jersey Medical SchoolNewarkNew JerseyUSA
出 版 物：《Stroke & Vascular Neurology》 (卒中与血管神经病学（英文）)
年 卷 期：2020年第5卷第4期
页 面：331-336页
核心收录：
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
主 题：admitted nasopharyngeal acute
摘 要：Background COVID-19,caused by SARS-CoV-2,is a global pandemic that has been an immense burden on healthcare systems all over the *** patients may be at higher risk for acute ischaemic stroke(AIS).We present our experience with AIS in patients with *** We reviewed all patients admitted to our hospital during a 6-week period with a positive nasopharyngeal swab test for *** these patients,we identified *** reviewed the demographics,clinical,laboratory,imaging characteristics,treatments received and outcomes of AIS in patients with *** We identified 683 patients admitted with COVID-19 during the study period,of which 20 patients had ***-vessel occlusion(LVO)was noted in 11 patients(55%).Intravenous alteplase was administered in four patients(20%)and mechanical thrombectomy was performed in five patients(25%).Respiratory symptoms preceded the onset of AIS in most of the patients(70%)by 1 to 21 *** in patients with AIS was 50%compared with 26%of all COVID-19 *** of these patients died due to non-neurological causes(70%).Three patients with AIS had clinical and imaging findings consistent with COVID-19,but were negative for multiple nasopharyngeal swab *** LVO was more common in patients with AIS and *** had more severe disease and higher mortality *** of the patients had respiratory symptoms preceding AIS by days to *** could explain certain patients with clinical picture of COVID-19 but negative nasopharyngeal swab tests.
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