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Asian Pacific Journal of Tropical Medicine 2024年第10期17卷 465-472页

作者： Priyanka Gupta Neeraj kumar Ravindra kumar Garg Hardeep Singh Malhotra Imran Rizvi Rajesh Verma praveen kumar sharma Ravi Uniyal Shweta Pandey Amita Jain Parul Jain Department of Neurology King George’s Medical UniversityLucknowIndia Department of Microbiology King George’s Medical UniversityLucknowIndia

Objective:To identify the clinical,laboratory,and radiological markers that could predict a positive GeneXpert result in patients suspected of tuberculous ***:In this prospective,observational study,patients with tuberculous meningitis were systematically *** clinical,laboratory[including cerebrospinal fluid(CSF)microscopy,culture,and GeneXpert],and neuroimaging factors were *** participants were administered anti-tuberculous treatment and corticosteroids.A six-month follow-up was done to evaluate the ***:Of the 116 patients studied,54(46.6%)tested positive for GeneXpert,while 62(53.4%)were *** cranial nerve involvement(OR 3.71,95%CI 1.052-13.09,P=0.04)and the presence of basal exudates on neuroimaging(OR 5.22,95%CI 2.03-13.42,P=0.001)emerged as independent predictive factors for a positive GeneXpert result.A positive CSF GeneXpert result(P=0.002)and drug resistance(P=0.004)were significantly linked to adverse ***,a high score on the Medical Research Council stageⅢ(OR 5.64,95%CI 1.18-26.87,P=0.03)and elevated CSF cell counts(OR 1.002,95%CI 1.00-1.001,P=0.03)were identified as independent predictors of poor ***:Third cranial nerve involvement and the presence of basal exudates were significant indicators of a positive GeneXpert *** stageⅢdisability and elevated CSF cell counts predicted poor outcomes.

关键词： Tuberculous meningitis Mycobacterium tuberculosis Cerebrospinal fluid Ziehl-Neelsen staining GeneXpert

Oxidative Stressand Antioxidant Responses in Young Leaves of Mulberry Plants Grown Under Nitrogen, Phosphorus or Potassium Deficiency

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Journal of Integrative Plant Biology 2007年第3期49卷 313-322页

作者： Rajesh kumar Tewari praveen kumar Parma Nand sharma Department of Botany University of LucknowLucknow226007India

The aim of this study was to associate the generation of reactive oxygen species （ROS） with Induced antloxidant responses and disturbed cellular redox environment in the nitrogen-（N）, phosphorus-（P）, or potassium-（K） deftcient mulberry （Morus alba L. var. Kanva-2） plants. The indicators of oxidative stress and cellular redox environment and antioxldant defense-related parameters were analyzed. Oeficlency of N, P or K suppressed growth, accelerated senescence, and decreased concentrations of chloroplastic pigments and glutathione. Lipid peroxidation and activities of superoxide dismutase, ascorbate peroxidase and glutathione reductase were also increased in these N, P, or K deprived plants. Concentration of hydrogen peroxide Increased in plants deficient in N or P. Oeficlency of N or P particularly altered the cellular redox environment as indicated by changes in the redox couples, namely ascorbic acid/total ascorbate decreased in P-, glutathione sulfydryl/total glutathione decreased in N-, and Increased in P-deficient plants. Activity staining of native gels for superoxide dismutase revealed Increased activity as Indicated by Increased intensity of bands, and induction of few new isoforms in P- and K-deficient plants. Oifferences in the patterns of superoxide dismutase isoforms and redox status （ascorbic acid/total ascorbate and glutathlone sulfydryl/total glutathione） Indicate that N-, P-, or K-deficiency altered antioxidant responses to varying extents in mulberry plants.

关键词： antioxidants potassium-deficiency lipid peroxidation Morus alba mulberry nitrogen-deficiency oxidative stress phosphorus-deficiency reactive oxygen species

Effect of cooling media on bead geometry,microstructure,and mechanical properties of wire arc additive manufactured IN718 alloy

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Advances in Manufacturing 2024年第1期12卷 124-149页

作者： Parveen kumar Satish kumar sharma Ratnesh kumar Raj Singh Department of Mechanical Engineering Thapar Institute of Engineering and TechnologyPatialaPunjab147004India

This work aims to present and explore thermal management techniques for the wire arc additive manufacturing(WAAM)of IN718 *** heat can be mitigated via air or water *** this study,the material was deposited under four different heat-input conditions with air or water *** air cooling,the layer is deposited in a normal atmospheric air environment,whereas with water cooling,the material is deposited inside a water tank by varying the water *** validate the air and water cooling thermal management techniques,IN718 single-pass and multilayer linear walls were deposited using the bidirectional gas metal arc welding based WAAM setup under four different heat input *** the deposition of single layers,the temperature profiles were recorded,and the geometric and microstructural features were *** multilayer wall structures,the mechanical properties(hardness,tensile strength,and elongation)were determined and assessed using the corresponding microstructural features explored through scanning electron microscopy(SEM),energy dispersive spectroscopy(EDS),and electron backscatter diffraction(EBSD)*** microstructure observed through SEM analysis in the building direction was found to be nonhomogenous compared with that in the deposition ***,water cooling was found to govern bead characteristics,such as wall width and *** grain size and anisotropy of the mechanical properties also decreased in the water-cooled ***,water cooling is an economical and efficient method to mitigate excessive heat accumulation in WAAM-deposited IN718.

关键词： Air cooling Water cooling IN718 Bead characteristics Microstructure Electron backscatter diffraction(EBSD)

Designing Sustainable Thermal Energy System with Electro-Photo Conversion

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Journal of Thermal Science 2024年第5期33卷 1642-1656页

作者： praveen BARMAVATU Sunil kumar KOTHAPALLI Abilash RADHAKRISHNAN Dani Jermisha RAILIS Department of Mechanical Engineering Faculty of EngineeringUniversidad Tecnologica MetropolitanaSantiago 7810003Chile SRKR Engineering College BhimavaramWest GodavariAndhra Pradesh 534204India Maria College of Engineering and Technology Attoor629177Tamil NaduIndia

Thermal energy conversion and also storage system is to advance knowledge and develop practical solutions at the intersection of micro and nano-scale engineering,energy conversion,and *** research addresses the challenge of enhancing these critical aspects to ensure prolonged system performance and durability in the context of evolving energy *** research analyses the anti-oxidation and filtration behaviours of micro and nano-scale structures in the context of electro-and photo-thermal energy conversion and also storage systems.A micro multiscale hierarchical structure strategy is presented to fabricate multi-scale double-layer porous wick evaporators with the electrospun nanofibers made of gelatin-polyamide 6(GPA6)and Ti_(3)C_(2)T_(x)MXene/silver nanowire with Cellulose Micro/NanoFibers(CMNF)cryogens by using spark plasma sintering(SPS)based high-pressure hydrothermal treatment *** excellent anti-oxidation effect was offered by coating the film in thermal conditions and the anti-oxidation properties were further examined from 500℃to850℃.The results are analysed using Matlab software to improve the efficiency of energy conversion processes by integrating nanostructures into thermal systems,to increase energy output while minimizing *** silver nanowire is with a heat transfer coefficient of 78%,a mass remaining rate of 98.7%,and an energy storage efficiency of 23.8%.This study enhances energy density and duration by integrating nanostructures into thermal systems while minimizing energy losses,and it not only exhibits excellent anti-oxidation properties but also possesses superior filtration capabilities for designing and engineering multifunctional nanomaterials.

关键词： heat exchanger micro and nano-scale structure electro-and photo-thermal energy conversion and storage system anti-oxidation filtration behaviour

A Novel Multi-objective Protection Coordination Scheme for a Microgrid with Optimal Deployment of Dual-setting ROCOV Based Relays

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Protection and Control of Modern Power Systems 2024年第4期9卷 23-38页

作者： praveen kumar Gupta Priyanshul Niranjan Niraj kumar Choudhary Nitin Singh Ravindra kumar Singh the Department of Electrical Engineering Motilal Nehru National Institute of Technology AllahabadPrayagraj 211004India

Relay coordination is crucial in electrical power systems to protect against malfunctions and damage caused by unexpected events like short *** address the challenge associated with the reverse direction of fault current,dual-setting(DS)directional over-current relays have evolved but failed to provide proper coordination during changes of load,generation,and *** the meantime,with the increasing number of DS relays,the total relay operating time tends to ***,this paper proposes a protection scheme based on the optimal deployment of conventional and dual-setting rate of change of voltage(DS-ROCOV)relays in distribution *** holds true for varying network topologies and is unaffected by variations in load and *** objective of the proposed scheme is to ensure reliable and efficient protection against faults in distribution systems by minimizing the overall operating time with the optimal number of DS-ROCOV *** proposed protection scheme’s performance is evaluated for different coordination time interval values as well as in different microgrid *** paper outlines the design and implementation of the proposed protection scheme which is validated on the modified IEEE 14-bus system using simulations in Matlab/Simulink.

关键词： Coordination time interval DS-ROCOV relay multi-objective optimization optimal-deployment protection coordination

Wharton’s jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury

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World Journal of Stem Cells 2024年第7期16卷 742-759页

作者： Prashasti sharma Dharmendra kumar Maurya Life Sciences Homi Bhabha National InstituteMumbai 400094MaharashtraIndia Radiation Biology&Health Sciences Division Bhabha Atomic Research CentreMumbai 400085MaharashtraIndia

Wharton’s jelly mesenchymal stem cells(WJ-MSCs)are gaining significant attention in regenerative medicine for their potential to treat degenerative diseases and mitigate radiation ***-MSCs are more naïve and have a better safety profile,making them suitable for both autologous and allogeneic *** review highlights the regenerative potential of WJ-MSCs and their clinical applications in mitigating various types of radiation *** this review,we will also describe why WJ-MSCs will become one of the most probable stem cells for future regenerative medicine along with a balanced view on their strengths and ***,the most updated literature related to both preclinical and clinical usage of WJ-MSCs for their potential application in the regeneration of tissues and organs will also be compiled.

关键词： Stem cells Wharton’s jelly mesenchymal stem cells Radiotherapy Xerostomia Lung fibrosis

Intrusion detection systems for wireless sensor networks using computational intelligence techniques

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Cybersecurity 2024年第2期7卷 81-95页

作者： Vaishnavi Sivagaminathan Manmohan sharma Santosh kumar Henge Lovely Professional University PhagwaraIndia

Network Intrusion Detection Systems(NIDS)are utilized to find hostile network *** can be accom-plished by looking at traffic network activity,but it takes a lot of *** NIDS heavily utilizes approaches for data extraction and machine learning to find *** terms of feature selection,NIDS is far more *** is accurate since anomaly identification uses a number of time-consuming *** of this,the feature selec-tion method influences how long it takes to analyze movement patterns and how clear it *** goal of the study is to provide NIDS with an attribute selection *** has been used for that *** Network Intrusion Detection System that is being developed will be able to identify any malicious activity in the network or any unusual behavior in the network,allowing the identification of the illegal activities and safeguarding the enormous amounts of confidential data belonging to the customers from being *** the research,datasets were produced utilising both a network infrastructure and a simulation *** is used to gather data packets whereas Cisco Packet Tracer is used to build a network in a simulated ***,a physical network consisting of six node MCUs connected to a laptop and a mobile hotspot,has been built and communication packets are being recorded using the Wireshark *** train several machine learning models,all the datasets that were gatheredcre-ated datasets from our own studies as well as some common datasets like NSDL and UNSW acquired from Kaggle-were ***,PsO,which is an optimization method,has been used with these ML algorithms for feature *** the research,KNN,decision trees,and ANN have all been combined with PSO for a specific case *** it was found demonstrated the classification methods PSO+ANN outperformed PSO+KNN and PSO+DT in this case study.

关键词： Network intrusion detection systems(NIDS) Cisco packet tracer Wireshark tool Machine learning PSO Cybersecurity Optimization

Improved Energy Management Strategy for Prosumer Buildings with Renewable Energy Sources and Battery Energy Storage Systems

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 381-392页

作者： Pavitra sharma Krishna kumar Saini Hitesh Datt Mathur Puneet Mishra Department of Electrical&Electronics Engineering Birla Institute of Technology&SciencePilaniIndia IEEE

The concept of utilizing microgrids(MGs)to convert buildings into prosumers is gaining massive popularity because of its economic and environmental *** pro-sumer buildings consist of renewable energy sources and usually install battery energy storage systems(BESSs)to deal with the uncertain nature of renewable energy ***,because of the high capital investment of BESS and the limitation of available energy,there is a need for an effective energy management strategy for prosumer buildings that maximizes the profit of building owner and increases the operating life span of *** this regard,this paper proposes an improved energy management strategy(IEMS)for the prosumer building to minimize the operating cost of MG and degradation factor of ***,to estimate the practical operating life span of BESS,this paper utilizes a non-linear battery degradation *** addition,a flexible load shifting(FLS)scheme is also developed and integrated into the proposed strategy to further improve its *** proposed strategy is tested for the real-time annual data of a grid-tied solar photovoltaic(PV)and BESS-powered AC-DC hybrid MG installed at a commercial ***,the scenario reduction technique is used to handle the uncertainty associated with generation and load *** validate the performance of the proposed strategy,the results of IEMS are compared with the well-established energy management *** simulation results verify that the proposed strategy substantially increases the profit of the building owner and operating life span of ***,FLS enhances the performance of IEMS by further improving the financial profit of MG owner and the life span of BESS,thus making the operation of prosumer building more economical and efficient.

关键词： Prosumer building battery energy storage system(BESS) battery degradation factor demand response energy management microgrid solar photovoltaic(PV)system

Pharmacological potential of Manilkara zapota(L.)***(Sapodilla):a narrative review

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Journal of Traditional Chinese Medicine 2024年第2期44卷 403-407页

作者： Priyanka sharma Aakash Deep Harish kumar Nitin Bansal Sanjiv kumar Arun Davinder kumar Department of Pharmaceutical Sciences Chaudhary Bansi Lal UniversityBhiwani 127021India Department of Pharmaceutical Sciences Maharishi Dayanand UniversityRohtak 124001India

Herbal medicine is safe and effective in treating various *** herbal medicine plays a tremendous role in treatment of various diseases and accompanying complications,hence herbal medicine requires remarkable attention in further research for the development of numerous active formulations for treatment of health *** plant needs special consideration for development and research of unidentified compound and characterization of novel active molecules that overcome multiple pathological *** genus Manilkara contains 135 plants around the *** overview discusses all the virtues of most important and commonly used plant Manilkara zapota(L.)***(***),also known as *** has various traditional beneficial effects in treatment of various diseases and disorders dating back to prehistoric times and used in ancient traditional system of herbal medicine.

关键词： herbal medicine Manilkara zapota phytoconstituents pharmacological activity review

SHT-based public auditing protocol with error tolerance in FDL-empowered IoVs

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Digital Communications and Networks 2024年第1期10卷 142-149页

作者： Kui Zhu Yongjun Ren Jian Shen Pandi Vijayakumar Pradip kumar sharma School of Computer and Software Nanjing University of Information Science&TechnologyNanjing210044China Peng Cheng Laboratory Shenzhen518000China Department of Computer Science and Engineering University College of Engineering TindivanamTamil Nadu604001India Department of Computing Science University of AberdeenAberdeenAB243UEUK

With the intelligentization of the Internet of Vehicles(lovs),Artificial Intelligence(Al)technology is becoming more and more essential,especially deep *** Deep Learning(FDL)is a novel distributed machine learning technology and is able to address the challenges like data security,privacy risks,and huge communication overheads from big raw data ***,FDL can only guarantee data security and privacy among multiple clients during data *** the data sets stored locally in clients are corrupted,including being tampered with and lost,the training results of the FDL in intelligent IoVs must be negatively *** this paper,we are the first to design a secure data auditing protocol to guarantee the integrity and availability of data sets in FDL-empowered ***,the cuckoo filter and Reed-Solomon codes are utilized to guarantee error tolerance,including efficient corrupted data locating and *** addition,a novel data structure,Skip Hash Table(SHT)is designed to optimize data ***,we illustrate the security of the scheme with the Computational Diffie-Hellman(CDH)assumption on bilinear *** theoretical analyses and performance evaluations demonstrate the security and efficiency of our scheme for data sets in FDL-empowered IoVs.

关键词： Internet of vehicles Federated deep learning Data security Data auditing Data locating and recovery