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Jamun(Syzygium cumini(L.)Skeels)seed bioactives and its biological activities:A review

Food Bioscience 2022年第6期50卷 2035-2050页

作者： Manoj Kumar Muzaffar Hasan Jose M.Lorenzo Sangram Dhumal Jyoti Nishad Nadeem Rais Aman Verma Sushil Changan Mrunal Deepak Barbhai Radha Deepak Chandran Ravi Pandiselvam Marisennayya Senapathy Abhijit Dey Prakash Chandra Pradhan pran mohankumar Vishal P.Deshmukh Ryszard Amarowicz Mohamed Mekhemar Baohong Zhang Chemical and Biochemical Processing Division ICAR – Central Institute for Research on Cotton TechnologyMumbai400019India Department of Biology East Carolina UniversityGreenvilleNC27858USA Agro Produce Processing Division ICAR – Central Institute of Agricultural EngineeringBhopal462038India Centro Tecnológico de la Carne de Galicia rúa Galicia n◦4Parque Tecnológico de GaliciaSan Cibrao das Viñas32900OurenseSpain Área de Tecnología de los Alimentos Facultad de Ciencias de OurenseUniversidad de Vigo32004OurenseSpain Division of Horticulture RCSM College of AgricultureKolhapur416004MaharashtraIndia Department of Food Technology Shaheed Rajguru College of Applied Sciences for WomenUniversity of Delhi110096India Department of Pharmacy Bhagwant UniversityAjmer305004India Division of Plant Improvement and Pest Management ICAR – Central Arid Zone Research Institute (CAZRI)JodhpurIndia Division of Crop Physiology Biochemistry and Post-Harvest TechnologyICAR – Central Potato Research InstituteShimla171001India School of Biological and Environmental Sciences Shoolini University of Biotechnology and Management SciencesSolan173229India Department of Veterinary Sciences and Animal Husbandry Amrita School of Agricultural SciencesAmrita Vishwa Vidyapeetham UniversityCoimbatore642109Tamil NaduIndia Division of Physiology Biochemistry and Post-Harvest TechnologyICAR – Central Plantation Crops Research Institute (CPCRI)Kasaragod671 124KeralaIndia Department of Rural Development and Agricultural Extension College of AgricultureWolaita Sodo UniversityWolaita SodoEthiopia Department of Life Sciences Presidency University86/1 College StreetKolkata700073West BengalIndia Sardarkrushinagar Dantiwada Agricultural University BanaskanthaGujarat385506India School of Agricultural Sciences Karunya Institute of Technology and SciencesCoimbatore641114Tamil NaduIndia Bharati Vidyapeeth (Deemed to be University) Yashwantrao Mohite Institute of ManagementKaradIndia Institute of Animal

Jamun(Syzygium cumini Skeels)is a nutritious fruit and has historically been used as both as an edible and a traditional *** jamun seed is an inedible by-product of the ***,their high concentration of phytochemicals makes them valuable components of *** studies on diverse biological activities of jamun seeds have warranted their application in human health and biomedical *** review paper discusses critically the phytochemical composition of jamun seeds and the bioactivities,including their antioxidant,anti-inflammatory,anti-cancer,antidiabetic,anti-microbial,anti-obesity,hepato-protective,cardio and gastro-protective *** bioactivity of jamun seed is related to the presence of phenols,flavonoids,steroids,alkaloids,triterpenoids,tannins,and *** research in vivo,and in vitro experiments with human and animal cell models support the idea that jamun seed extract can be valuable additions in food and biomedical fields due to the diverse bio-functional ***,in-depth and systematic in vivo clinical trials using human subjects must be conducted to confirm the safe consumption limit and establish other therapeutic roles of jamun seeds for their abundant utilization as a nutraceutical or pharmacological ***,research is required to understand the exact mechanisms of the bioactivities exhibited by jamun seeds.

关键词： Bioactivity Jamun seeds Phytochemicals Health promoting activity

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Apple(Malus domestica Borkh.)seed:A review on health promoting bioactivities and its application as functional food ingredient

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Food Bioscience 2022年第6期50卷 2051-2066页

作者： Manoj Kumar Mrunal D.Barbhai Tuba Esatbeyoglu Baohong Zhang Vijay Sheri Sangram Dhumal Nadeem Rais Radha Eman Mohammad Said Al Masry Deepak Chandran Ravi Pandiselvam Marisennayya Senapathy Abhijit Dey Sheetal Vishal Deshmukh Mohamed El Sayed Negm Marthandan Vishvanathan Sangeetha Kizhakkumkara Sathyaseelan Sabareeshwari Viswanathan pran mohankumar José M.Lorenzo Chemical and Biochemical Processing Division ICAR—Central Institute for Research on Cotton TechnologyMumbai400019India Department of Food Development and Food Quality Institute of Food Science and Human NutritionGottfried Wilhelm Leibniz University HannoverAm Kleinen Felde 3030167HannoverGermany Department of Biology East Carolina UniversityGreenville27858USA Division of Horticulture RCSM College of AgricultureKolhapur416004India Department of Pharmacy Bhagwant UniversityAjmerRajasthan305004India School of Biological and Environmental Sciences Shoolini University of Biotechnology and Management SciencesSolan173229India Faculty of Libral Arts and Ancient Indian Wisdom Shoolini UniversitySolan173229India Department of Veterinary Sciences and Animal Husbandry Amrita School of Agricultural SciencesAmrita Vishwa Vidyapeetham UniversityCoimbatore642109India Division of Physiology Biochemistry and Post-Harvest TechnologyICAR-Central Plantation Crops Research Institute (CPCRI)KasaragodKerala671124India Department of Rural Development and Agricultural Extension College of AgricultureWolaita Sodo UniversityWolaita SodoSNNPREthiopia Department of Life Sciences Presidency University86/1 College StreetKolkata700073India Bharati Vidyapeeth (Deemed to be University) Yashwantrao Mohite Institute of ManagementKaradIndia Cotton Research Institute Agriculture Research CenterGiza3725004Egypt Department of Seed Science and Technology Amrita School of Agricultural SciencesAmrita Vishwa Vidyapeetham UniversityCoimbatore642109India Department of Plantation Crops and Spices Kerala Agricultural UniversityVellanikkaraThrissur680656KeralaIndia Department of Soil Science and Agricultural Chemistry Amrita School of Agricultural SciencesAmrita Vishwa Vidyapeetham UniversityCoimbatore642109India School of Agricultural Sciences Karunya Institute of Technology and SciencesCoimbatore - 641114India Centro Tecnológico de la Carne de Galicia Parque Tecnológico de GaliciaAvd.Galicia n° 4Sa

Recent trends in food industry focus on utilization of fruit processing waste and by-products as novel ingredients due to their nutritional *** seed is one such novel ingredient that can find application as functional ingredient in food,nutraceutical and pharmaceutical *** existing studies suggest that apple seed is a rich source of amino acids,fatty acids and polyphenolic *** review discusses the nutritional and phytochemical profile as well as biological activities exhibited by the apple *** also highlights the current application of apple seed in food,pharmaceutical and nutraceutical industries along with the safety aspects considering the presence of *** apple seed meal,extracts or seed oil as novel ingredient can find various industrial applications given their dense nutritional *** their functionality,rigorous and extensive research is required to promote its usage at industrial level for harnessing the benefits of apple seeds.

关键词： Apple seed Biological activities Industrial applications Phytochemicals

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Perspectives on Higgs boson and supersymmetry

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Frontiers of physics 2013年第3期8卷 294-301页

作者： pran Nath Department of Physics Northeastern University Boston MA 02115-5005 USA

We review the recent discovery of the Higgs like particle at - 125 GeV and its implications for par- ticle physics models. Specifically the implications of the relatively high Higgs mass for the discovery of supersymmetry are discussed. Several related topics such as naturalness and supersymmetry, dark matter and unification are also discussed.

关键词： 125 GeV Higgs supersymmetry (SUSY) dark matter unification

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Geomorphic signatures of active tectonics in Subansiri River Basin, eastern Himalayas

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Journal of Mountain Science 2020年第6期17卷 1523-1540页

作者： Diganta KUMAR Bhagawat pran DUARAH Department of Geological Sciences Gauhati UniversityGuwahatiAssam-781014India

The Subansiri,a major tributary of the Brahmaputra with its catchment area(35763 km^2)spreading almost entirely in the Eastern Himalayas across almost all the major and local tectonic features in the area witnesses large numbers of seismic *** tectonic indices like relief and slope,drainage pattern,longitudinal profile,valley profile,hypsometry,valley asymmetry factors and transverse topographic symmetry index,stream length gradient,valley floor-height ratio extracted from SRTM 3 arcsecond data prove that the evolving basin morphology has substantial contribution from the Himalayan *** data are incorporated in the study to establish the potentially active tectonic elements in the catchment *** study shows that the western part of the Subansiri River Basin is profoundly tilted towards north in the upper catchment and towards east in the lower and middle part of the *** predominant tectonic movements in the western part of the basin caused the tilting of the basin towards north in the upstream and towards east in the middle and lower parts.

关键词： Eastern Himalayas Active tectonics Subansiri Geomorphometry SRTM DEM Seismicity

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Development of a set of SSR markers for genetic polymorphism detection and interspecific hybrid jute breeding

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The Crop Journal 2017年第5期5卷 416-429页

作者： Dipnarayan Saha Rajeev Singh Rana Sukla Chakraborty Subhojit Datta Arroju Anil Kumar Asim Kumar Chakraborty pran Gobinda Karmakar Division of Crop Improvement Indian Council of Agricultural Research (ICAR)-Central Research Institute for Jute and Allied Fibers

Corchorus capsularis(white jute) and C. olitorius(dark jute) are the two principal cultivated spedes of jute that produce natural bast fiber of commercial importance. We have identified 4509 simple sequence repeat(SSR) loci from 34,163 unigene sequences of C. capsularis to develop a non-redundant set of 2079 flanking primer pairs. Among the SSRs, trinudeotide repeats were most frequent(60%) followed by dinucleotide repeats(37.6%). Annotation of the SSR-containing unigenes revealed their putative functions in various biological and molecular processes, including responses to biotic and abiotic signals. Eighteen expressed gene-derived SSR(eSSR) markers were successfully mapped to the existing single-nucleotide polymorphism(SNP) linkage map of jute,providing additional anchor points. Amplification of 72% of the 74 randomly selected primer pairs was successful in a panel of 24 jute accessions, comprising five and twelve accessions of *** and C. olitorius, respectively, and seven wild jute spedes. Forty-three primer pairs produced an average of 2.7 alleles and 58.1% polymorphism in a panel of 24 jute accessions. The mean PIC value was 0.34 but some markers showed PIC values higher than 0.5, suggesting that these markers can efficiently measure genetic diversity and serve for mapping of quantitative trait loci(QTLs) in jute. A primer polymorphism survey with parents of a wide-hybridized population between a cultivated jute and its wild relative revealed their efficacy for interspecific hybrid identificatioii. For ready accessibility of jute eSSR primers, we compiled all information in a user-friendly web database, JuteMarkerdb(http://***/) for the first time in *** eSSR resource in jute is expected to be of use in characterization of germplasm, interspecific hybrid and variety identification, and marker-assisted breeding of superior-quality jute.

关键词： Database Genic-SSR Jute Interspecific hybrid identification Unigene sequences

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Blockchain-based COVID vaccination registration and monitoring

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Blockchain(Research and Applications) 2022年第4期3卷 44-55页

作者： Shirajus Salekin Nabil Md Sabbir Alam pran Ali Abrar Al Haque Narayan Ranjan Chakraborty Mohammad Jabed Morshed Chowdhury Md Sadek Ferdous Daffodil International University Dhaka1207Bangladesh La Trobe University VIC3086Australia BRAC University Dhaka1212Bangladesh

COVID-19 has changed almost all aspects of our *** around the world have imposed lockdowns to slow down the ***,we have found the vaccine,in fact,a good number of ***,managing the testing and vaccination process of the total population is a mammoth ***,there are always delays or data silo problems in multi-organizational ***,streamlining this process is vital to improve efficiency and save more *** of its effective data sharing mechanism among different entities with a number of security features,blockchain can be an effective tool for different applications in the health ***,blockchain provides a distributed system along with greater privacy,transparency,and *** this article,we have presented a blockchain-based system that seamlessly integrates testing and vaccination systems,allowing the system to be *** instant verification of any tamper-proof COVID-19 test result has been developed,which will serve as“Test Certificates”.A transparent and efficient vaccination system has also been exhibited and implemented as the“Digital Vaccine Passport”(DVP)*** infection rate-based prioritization will ensure a transparent and fair vaccination process as well as tackle the distribution issue of the limited amount of *** comparative review with other existing works is also discussed,highlighting a clear difference from the existing *** proposed system is distinctive on the basis of prioritization of vaccines and seamless integration of test certificates and vaccine passports,which will aid in controlling the pandemic *** system will also be handy in the case of tackling any future pandemics initially.

关键词： COVID-19 Blockchain Solidity Digital vaccine passport Vaccination

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An Evolutionary Algorithm Coupled to an Outranking Method for the Multicriteria Shortest Paths Problem

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American Journal of Operations Research 2019年第3期9卷 114-128页

作者： Frédéric Guidana Gazawa Kolyang Irépran Damakoa Department of Mathematics and Computer Science Faculty of Science The University of Ngaoundere Ngaoundere Cameroon Department of Computer Science Higher Teacher’s Training College The University of Maroua Maroua Cameroon Department of Applied Mathematics and Computer Science School of Geology and Mining Engineering The University of Ngaoundere Ngaoundere Cameroon

In this article, we are interested in solving a combinatorial optimization problem, the shortest path problem in a multi-attribute graph, by the out-ranking methods. A multi-attribute graph has simultaneously qualitative and quantitative criteria. This situation gives rise to incomparable paths thus forming the Pareto front. Outranking methods in Multi-criteria Decision Making (MCDM) are the only methods that can take into account this situation (incomparability of actions). After presenting the categories of Multi-criteria Decision Making (MCDM) and the difficulties related to the problems of the shortest paths, we propose an evolutionary algorithm based on the outranking methods to solve the problem of finding “best” paths in a multi-attribute graph with non-additive criteria. Our approach is based on the exploration of induced subgraphs of the outranking graph. Properties have been established to serve as algorithmic basis. Numerical experiments have been carried out and the results presented in this article.

关键词： Multi-Criteria Decision Making Evolutionary Algorithm Shortest Path Outranking Method Induced Subgraphs

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面包小麦产量及其构成性状的杂种优势研究

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国外作物育种 1999年第3期18卷 33-34页

作者： pran,KDP Haqu.,MF

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艾滋病的眼部感染和肿瘤

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德国医学 1989年第3期6卷 179-180页

作者： pran.,F 宋佩辉

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The Development of the Electrophilic α-Cyanation Reactions

The Development of the Electrophilic α-Cyanation Reactions

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中国化学会第十四届全国有机合成化学学术研讨会

作者： Jia-Shen Qiu pran Gopal Karmaker Di Wu Hong-Quan Yin Fu-Xue Chen School of Chemistry & Chemical Engineering Beijing Institute of Technology

Cyano exists extensively in natural compounds and biologically active molecules as a result of its fascinating bioactivity, together with its compelling transformations to divers functional groups. Despite virtually developed nucleophilic addition reactions of cyanide to varying substrates bearing an sp prochiral moiety such as C=C, C=O, and C=N double bonds, the directly catalytic enantioselective introduction of cyano group to the sp carbon chain remains challenging. Early in 2015, we firstly found the hypervalent iodine cyano reagent 1 serving as a very good cationic cyano source thus readily achieving the racemic α-cyanation of β-keto ester/amine without additional catalyst in DMF promptly. Considering the tuneable reactivity of cyanates, 4-acetylphenyl cyanate(2) was employed as the electrophilic cyano reagent to develop a highly enantioselective α-cyanation of cyclic β-keto carbonyls by Lewis acid catalysis. Using the same reagent, a series of all-carbon quaternary 3-aryl-3-cyano oxindoles were synthesized by a Zinc complex of a chiral pincer ligand as the catalyst in high yields and excellent enantioselectivities for the first time in our group.

关键词： asymmetric catalysis α-cyanation enantioselectivity nitriles electrophilic substitution

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