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Regulation of sleep by astrocytes in the hypothalamic ventrolateral preoptic nucleus

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Neural Regeneration Research 2025年第4期20卷 1098-1100页

作者： jae-Hong kim Ruqayya Afridi Il-Sung Jang Maan Gee Lee Kyoungho Suk Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents School of MedicineKyungpook National UniversityDaeguRepublic of Korea Department of Pharmacology School of MedicineKyungpook National UniversityDaeguRepublic of Korea Department of Pharmacology School of DentistryKyungpook National UniversityDaeguRepublic of Korea Brain Science&Engineering Institute Kyungpook National UniversityDaeguRepublic of Korea

Astrocytes are functionally dynamic cells that support neurons in multiple ways throughout an organism’s *** astrocytic regulation of neuronal activity has been increasingly recognized in recent *** are now recognized as playing a more complex role than mere bystanders in the central nervous ***,their role in regulating the sleep neurocircuitry is not well *** this perspective,we highlight the role of astrocytes in sleep modulation,with a particular focus on regulatory mechanisms related to the ventrolateral preoptic nucleus(VLPO)of the *** briefly discuss recent literature reporting the role of VLPO astrocytes in regulating sleep-associated behaviors.

关键词： sleep ventrolateral astrocytes

Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer

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World Journal of Gastroenterology 2014年第15期20卷 4370-4376页

作者： Bun kim Soo Jung Park jae Hee Cheon Tae Il kim Won Ho kim Sung pil Hong Department of Internal Medicine Institute of GastroenterologyYonsei University College of MedicineSeoul 120-752South Korea

AIM: To evaluate the clinicopathological features of colorectal cancer (CRC) with a v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) mutation and its molecular interaction with microsatellite instability (MSI) an... 详细信息

关键词： BRAF Colorectal cancer Molecular features Chemotherapy response Prognosis

Conventional endoscopic features are not sufficient to differentiate small, early colorectal cancer

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World Journal of Gastroenterology 2014年第21期20卷 6586-6593页

作者： Wan Park Bun kim Soo Jung Park jae Hee Cheon Tae Il kim Won Ho kim Sung pil Hong Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of MedicineSeoul 120-752South Korea

AIM: To evaluate the depth of invasion of small, early colorectal cancers (ECCs) using conventional endoscopic features.

关键词： Colonoscopy Colorectal neoplasms Differential diagnosis

Effect of gadolinium incorporation on optical characteristics of YNbO_4:Eu^(3+) phosphors for lamp applications

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Journal of Rare Earths 2012年第3期30卷 205-209页

作者： Sung Hwan Choi G. Anoop Dong Wook Suh Kyung pil kim Hyun Ju Lee jae Soo Yoo Display Materials Laboratory School of Chemical Engineering and Materials Science Chung-Ang University

Eu3＋-doped （Y,Gd）NbO4 phosphor was synthesized by solid-state reaction for possible application in cold cathode fluorescent lamps. A broad absorption band with peak maximum at 272 nm was observed which was due to the charge transfer between Eu3＋ ions and neighboring oxygen anions. A deep red emission at the peak wavelength of 612 nm was observed which could be attributed to the 5D0→7F2 transition in Eu3＋ ions. The highest luminance for Y1-x-yGdyNbO4：Eux3＋ under 254 nm excitation was achieved at Eu3＋ concentration of 18 mol.% （x=0.18） and Gd3＋ concentration of 8.2 mol.% （y=0.082）. The luminance of Y0.738Gd0.082NbO4：Eu3＋0.18 was higher than that of a typical commercial phosphor Y2O3：Eu3＋ and the CIE chromaticity coordinate was （0.6490, 0.3506）, which was deeper than that of Y2O3：Eu3＋. The particle size of the synthesized phosphors was controlled by the NaCl flux and particle size as high as 8 μm with uniform size distribution of particles was obtained.

关键词： YNbO4:Eu oxide phosphors rare earths

THE ENERGY CONSERVATIONS AND LOWER BOUNDS FOR POSSIBLE SINGULAR SOLUTIONS TO THE 3D INCOMPRESSIBLE MHD EQUATIONS

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Acta Mathematica Scientia 2020年第1期40卷 237-244页

作者： jae-Myoung kim Department of Mathematics Education Andong National University AndongRepublic of Korea

In this note,we give a new proof to the energy conservation for the weak solutions of the incompressible 3D MHD ***,we give the lower bounds for possible singular solutions to the incompressible 3D MHD equations.

关键词： MHD equation lower bounds incompressible

Effect of soil pH on the sorption capacity of soil organic matter for polycyclic aromatic hydrocarbons in unsaturated soils

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Pedosphere 2023年第2期33卷 365-371页

作者： pil-Gon kim Abhrajyoti TARAFDAR Jung-Hwan KWON Division of Environmental Science and Ecological Engineering Korea University145 Anam-roSeongbuk-guSeoul 02841(Korea)

Sorption by soil organic matter(SOM)is considered the most important process affecting the bioavailability of hydrophobic organic chemicals(HOCs)in *** sorption capacity of SOM for HOCs is affected by many environmental *** this study,we investigated the effects of soil pH and water saturation level on HOC sorption capacity of SOM using batch sorption *** of soil organic carbon-water partition coefficient(K_(OC))of six selected polycyclic aromatic hydrocarbons(PAHs)were measured in an artificial soil under various soil pH and water saturation *** sampling was used to measure K_(OC)with polydimethylsiloxane as the sampling *** of soil pH,K_(OC)increased with increasing soil water saturation level for lower-molecular-weight *** contrast,K_(OC)decreased with increasing soil water saturation level for higher-molecular-weight *** some fluctuations,K_(OC)tended to decrease with increasing soil pH at all water saturation *** indicates that earlier studies on the effects of soil pH on K_(OC)under saturated conditions could be extended to unsaturated *** K_(OC)tendencies were reproduced in three different natural soils,suggesting that the effects of soil water saturation level and pH might be generalized,at least for *** PAH sorption capacity of SOM was found to be resilient under dynamic soil pH conditions,which can be used to adjust the effects of soil pH.

关键词： contaminated soil hydrophobic organic chemical partition coefficient passive sampling pollutant soil water saturation level

Intestinal Behet's disease appearing during treatment with adalimumab in a patient with ankylosing spondylitis

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World Journal of Gastroenterology 2013年第32期19卷 5389-5392页

作者： Sook Hee Chung Soo Jung Park Sung pil Hong jae Hee Cheon Tae Il kim Won Ho kim Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of Medicine

Behet’s disease(BD)is a chronic inflammatory disease affecting multiple organ systems,such as the skin,joints,blood vessels,central nervous system,and gastrointestinal *** BD is characterized by intestinal ulcerations and gastrointestinal *** medical treatment of intestinal BD includes corticosteroids and *** have been several reports of tumor necrosis factor-α (TNF-α)blockers being successful in treatment of refractory intestinal ***,we report on a patient who was diagnosed with intestinal BD despite treatment with the fully humanized TNF-α blocker(adalimumab)for underlying ankylosing *** patient achieved clinical remission and complete mucosal healing through the addition of a steroid and azathioprine to the adalimumab regimen.

关键词： Intestinal Behet's disease Tumor necrosis factor-α Adalimumab

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World Journal of Gastroenterology 2014年第45期20卷 17120-17126页

作者： Sook Hee Chung Soo Jung Park Hye Sun Lee Sung pil Hong jae Hee Cheon Tae Ⅱ kim Won Ho kim Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of Medicine Department of Internal Medicine and institute of Gastroenterology Ajou University College of Medicine Department of Biostatistics Yonsei University College of Medicine

AIM: To investigate differences of clinical characteristics and disease courses between familial and sporadic inflammatory bowel disease (IBD) patients.

关键词： Inflammatory bowel disease Family history Crohn’ s disease Ulcerative colitis Clinical characteristics

Rice breeding for low methane and high yields

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Plant Communications 2024年第5期5卷 94-96页

作者： Suvendu Das pil Joo kim Institute of Agriculture and Life Sciences Gyeongsang National UniversityJinju 660-701South Korea Division of Applied Life Science Gyeongsang National UniversityJinju 660-701South Korea

Rice is the staple food for more than half of the world’s population,and the demand for rice is expected to increase by 28%by 2050(Jiang et al.,2017).However,rice production is one of the largest anthropogenic sources of the potent greenhouse gas methane(CH4),accounting for 22%of total agricultural CH4 emissions(Qian et al.,2023).Therefore,to achieve sustainable intensification of rice cultivation,it is necessary to increase yields while reducing CH4 *** management techniques to reduce CH4 emissions while maintaining high yields have been studied extensively over the past few decades,but crop breeding to reduce CH4 emissions without compromising yields has received less attention(Kwon et al.,2023).

关键词： breeding methane yields