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First 150 years of catatonia:Looking back at its complicated history and forward to the road ahead

World Journal of Psychiatry 2024年第5期14卷 600-606页

作者： Levente Csihi Gabor S Ungvari Stanley N caroff Gábor Gazdag Department of Psychiatry and Psychiatric Rehabilitation Jahn Ferenc South Pest HospitalBudapest 1204Hungary Division of Psychiatry School of MedicineUniversity of Western AustraliaCrawley 6009Western AustraliaAustralia Section of Psychiatry University of Notre DameFremantle 6160Western AustraliaAustralia Behavioral Health Service Corporal Michael J CresenczVeterans Affairs Medical CenterPhiladelphiaPA 19104United States Department of Psychiatry University of PennsylvaniaPerelman School of MedicinePhiladelphiaPA 19104United States Department of Psychiatry and Psychotherapy Faculty of MedicineSemmelweis UniversityBudapest 1083Hungary

Karl Ludwig Kahlbaum(1828-1899)was the first to conceptualize and describe the main clinical features of a novel psychiatric illness,which he termed catatonia in his groundbreaking monograph published 150 years *** Kahlbaum postulated catatonia as a separate disease entity characterized by psychomotor symptoms and a cyclical course,a close examination of his 26 cases reveals that most of them presented with motor symptom complexes or syndromes associated with various psychiatric and medical *** his classification system,Kraepelin categorized catatonic motor symptoms that occur in combination with psychotic symptoms and typically have a poor prognosis within his dementia praecox(schizophrenia)disease *** of the substantial influence of Kraepelin’s classification,catatonia was predominantly perceived as a component of schizophrenia for most of the 20th ***,with the advent of the psychopharmacotherapy era starting from the early 1950s,interest in catatonia in both clinical practice and research subsided until the early *** past two decades have witnessed a resurgence of interest in *** Diagnostic and Statistical Manual of Mental Disorders Fifth Edition,marked a paradigmatic shift by acknowledging that catatonia can occur secondary to various psychiatric and medical *** introduction of an independent diagnostic category termed“Catatonia Not Otherwise Specified”significantly stimulated research in this *** authors briefly review the history and findings of recent catatonia research and highlight promising directions for future exploration.

关键词： Catatonia Historical overview Psychopharmacology Diagnostic and Statistical Manual of Mental Disorders-5 Wernicke-Kleist-Leonhard school

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Anomalous negative magnetoresistance in quantum dot Josephson junctions with Kondo correlations

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Science China(Physics,Mechanics & Astronomy) 2024年第8期67卷 3-13页

作者： Mingtang Deng Chunlin Yu Guangyao Huang Rosa López phil.ppe.caroff Sepideh Ghalamestani Gloria Platero Hongqi Xu Institute for Quantum Information&State Key Laboratory of High Performance Computing College of Computer Science and TechnologyNational University of Defense TechnologyChangsha 410073China NanoLund and Division of Solid State Physics Lund UniversityLund S-22100Sweden China Greatwall Quantum Laboratory Changsha 410006China Institut de Física Interdisciplinària i de Sistemes Complexos IFISC Palma de Mallorca E-07122Spain Instituto de Ciencia de Materiales de Madrid Madrid 28049Spain Beijing Key Laboratory of Quantum Devices Key Laboratory for the Physics and Chemistry of Nanodevicesand Department of ElectronicsPeking UniversityBeijing 100871China Beijing Academy of Quantum Information Sciences Beijing 100193China Hefei National Laboratory Hefei 230088China

The interplay between superconductivity and the Kondo effect has stimulated significant interest in condensed matter *** compete when their critical temperatures are close and can give rise to a quantum phase transition that can mimic Majorana zero ***,we have fabricated and measured Al-InSb nanowire quantum dot-Al *** the Kondo regime,a supercurrent-induced zero-bias conductance peak *** zero-bias peak shows an anomalous negative magnetoresistance(NMR)at weak magnetic *** attribute this anomalous NMR to quasiparticle trapping at vortices in the superconductor leads as a weak magnetic field is *** trapping effect lowers the quasiparticle-caused dissipation and thus enhances the Josephson *** work connects the vortex physics and the supercurrent tunneling in Kondo regimes and can help further understand the physics of Josephson quantum dot system.

关键词： quantum dot Kondo correlation InSb nanowire quasiparticle trapping

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Experimental study on influence of blade angle and particle size on particle mechanics on a batch-operated single floor of a multiple hearth furnace

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Particuology 2024年第2期85卷 224-240页

作者： Max Kriegeskorte Nikoline Hilse phil Spatz Viktor Scherer Institute for Energy Plant Technology(LEAT) Ruhr University BochumUniversitätsstraβe 15044780 BochumGermany

In industry,multiple hearth furnaces are used for the thermal treatment of particulate *** current contribution concentrates on the experimental analysis of particle mechanics for a batch-operated single floor of a multiple hearth *** particles are agitated on the circular floor by a single,rotating rabble arm equipped with three flat rabble blades of 10 mm *** blade angle,defined as the angle,which the blade is inclined against the tangential direction,is varied from 0°to 90°.A single layer of spherical polyoxymethylene(POM)particles with three different diameters(5,10 and 20 mm)is placed on the *** analyze the results,two parameters have been extracted from image analysis when the bed of particles is agitated,first,the area not covered by particles and second,the frequency distribution of the mean distance among the *** particle free surface area increases with the inclination of the *** evolution of the particle free surface area differs for the different particle *** general,the maximum particle free area for all blade angles is the largest for the 5 mm particles followed by the 20 mm *** the 10 mm particles,the particle free surface area starts for a blade angle of 0°at larger values than for the 20 mm particles but the values fall below the values for the 20 mm particles for larger blade *** reason for this behavior is discussed in *** mean distance among the particles is a parameter characterizing the length scales dominating the effects on the *** frequency distribution of the mean distance among particles provides infor-mation about the morphology of the particle bulk,for example,whether the free surface area is inter-spersed with particles.

关键词： Hearth furnace floor Particle movement Spherical particles Particle free surface area Mean distance among particles

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A framework for dynamic modelling of railway track switches considering the switch blades,actuators and control systems

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Railway Engineering Science 2024年第2期32卷 162-176页

作者： Saikat Dutta Tim Harrison Christopher Ward Roger Dixon phil Winship Institute of Thermofluids School of Mechanical EngineeringUniversity of LeedsLeedsWest YorkshireUK Wolfson School of Mechanical Electrical and Manufacturing EngineeringLoughborough UniversityLoughboroughLeicestershireUK Birmingham Centre for Railway Research and Education School of EngineeringUniversity of BirminghamBirminghamWest MidlandsUK Network Rail Milton KeynesBuckinghamshireUK

The main contribution of this paper is the development and demonstration of a novel methodology that can be followed to develop a simulation twin of a railway track switch system to test the functionality in a digital *** is important because,globally,railway track switches are used to allow trains to change routes;they are a key part of all railway ***,because track switches are single points of failure and safety-critical,their inability to operate correctly can cause significant delays and concomitant *** order to better understand the dynamic behaviour of switches during operation,this paper has developed a full simulation twin of a complete track switch *** approach fuses finite element for the rail bending and motion,with physics-based models of the electromechanical actuator system and the control ***,it provides researchers and engineers the opportunity to explore and understand the design space around the dynamic operation of new switches and switch machines before they are *** is useful for looking at the modification or monitoring of existing switches,and it becomes even more important when new switch concepts are being considered and *** simulation is capable of running in real time or faster meaning designs can be iterated and checked *** paper describes the modelling approach,demonstrates the methodology by developing the system model for a novel“REPOINT”switch system,and evaluates the system level performance against the dynamic performance requirements for the *** the context of that case study,it is found that the proposed new actuation system as designed can meet(and exceed)the system performance requirements,and that the fault tolerance built into the actuation ensures continued operation after a single actuator failure.

关键词： Railway track switch Mathematical modelling Redundant actuation Finite element analysis

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Biorenewable materials for water remediation: The central role of cellulose in achieving sustainability

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Journal of Bioresources and Bioproducts 2024年第3期9卷 253-282页

作者： Kirti Mishra Samarjeet Singh Siwal Thandiwe Sithole Nirankar Singh phil Hart Vijay Kumar Thakur Department of Chemistry M.M.Engineering CollegeMaharishi Markandeshwar(Deemed to be University)Haryana 133207India Department of Chemical Engineering University of JohannesburgDoornfontein 2088South Africa Biorefining and Advanced Materials Research Center Scotland’s Rural CollegeEdinburgh EH93JGUnited Kingdom Renewable and Sustainable Energy Research Centre Technology Innovation InstituteAbu Dhabi 9639United Arab Emirates School of Engineering University of Petroleum&Energy StudiesDehradun 248007India

As the population increases and manufacturing grows,greenhouse gas and other harmful emissions *** with chemicals such as dyes,pesticides,pharmaceuticals,oil,heavy metals or radionuclides,wastewater purification has become an urgent *** technologies exist that can remove these contaminants from wastewater sources,but they often demand high energy and/or high cost,and in some cases produce contaminant laden sludge that requires safe *** need for methods which are less capital intensive,less operationally costly and more environmentally friendly is ***-based materials have emerged as promising candidates for wastewater treatment due to their renewability,low cost,biodegradability,hydrophilicity,and antimicrobial *** this review article,we focussed on developing sustainable and biodegradable cellulose-based materials for wastewater *** article deals with cellulose-based materials’scope and their conversion into valuable products like hydrogel,aerogel,cellulose composites,and *** cellulose-based materials have no harmful environmental impact and are *** modified cellulose-based materials applying as membrane,adsorbent,sorbent,and beads to purify the wastewater were ***,the challenges and future prospects of cellulose-based materials for wastewater treatment were considered,emphasizing their potential to be sustainable and eco-friendly alternatives to traditional materials used in wastewater treatment.

关键词： Cellulose Wastewater treatment Hydrogel Nanocrystal Cellulose membrane

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The Use of Far Infrared Treatment Prior to Exercise in Horses: An mfBIA and Acoustic Myography Three Case Study

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Open Journal of Veterinary Medicine 2024年第4期14卷 69-89页

作者： Adrian Harrison D.phil Department for Veterinary and Animal Sciences (IVH) Faculty of Health & Medical Sciences University of Copenhagen K&#248benhavn Denmark

Background: Acute effects of Far Infrared (FIR) treatment in horses are unknown, especially short periods of 30 minutes, as is any effect on such muscle parameters as warm-up balance, overall exercise balance and laterality asymmetries. Aim: This study examines three equine cases in detail to measure any effects of a short period of FIR treatment. Methods: Multi-frequency bioimpedance (mfBIA) and acoustic myography (AMG), non-invasive techniques, were applied pre- and post-treatment with FIR to the back (T5-L4/5) and for *** dorsi and *** medius was recorded during a 15-minute warm-up regimen. mfBIA parameters included extracellular resistance (Re), centre frequency (fc), membrane capacitance (Mc), intracellular resistance (Ri) and phase angle (PA) which indicates level of training and health status. Results: FIR treatment responses for mfBIA parameters were found to be horse-specific and different, whilst in terms of AMG, FIR treatment for 30 minutes had a beneficial effect on overall balance in all three horses (5 out of 6 muscles), and a beneficial effect on the AMG parameter ST (force symmetry) in all three horses (6 out of 6 muscles). An overall improvement for combined balance and ST values for both muscles and all three horses of 86% was noted with FIR treatment, compared to 56% without. Conclusions: This preliminary study of FIR treatment in three horses, has been found to result in an overall improvement in combined balance and ST values for both muscles. FIR has potential as a promising treatment to reduce the risk of warm-up-related injuries in athletic horses.

关键词： Equine FIR Muscle Balance Muscle Force Injury Prevention

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Evaluating Global Navigation Satellite System (GNSS) Constellation Performance for Unmanned Aerial Vehicle (UAV) Navigation Precision

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Journal of Computer and Communications 2024年第9期12卷 39-62页

作者： Ahad Alotaibi Chris Chatwin phil Birch Department of Engineering and Design School of Engineering and Informatics University of Sussex Brighton UK

Accurate localization is paramount for unmanned aerial vehicles (UAVs) spanning various technical and industrial domains, necessitating a comprehensive assessment of global navigation satellite system (GNSS) precision. This study investigates the performance of distinct GNSS constellations in determining the precise location of a building utilizing a high-precision GNSS receiver. The receiver, incorporating advanced multi-frequency and full-constellation positioning capabilities, was integrated with a smartphone via Bluetooth to enable the UAV’s acquisition of centimeter-level positioning data. Sequential utilization of single satellite systems—such as GPS-only, GLONASS-only, Galileo-only, SBAS-only, and BeiDou-only—facilitated the documentation of latitude and longitude coordinates for the designated building. Subsequent comparison of these coordinates with a specialized Geographic Information System (GIS) was conducted to evaluate their positional accuracy. The comparative analysis underscores significant variability in the precision offered by each satellite constellation, providing valuable insights for optimizing UAV navigation across GIS, IoT, construction, and other sectors requiring high-precision localization. This research underscores the significance of high-precision GNSS receivers in enhancing UAV-based geospatial assessments, emphasizing the critical selection of appropriate satellite systems for tailored localization tasks. The study contributes to advancing UAV navigation strategies, ensuring robust and accurate geospatial data collection within diverse operational frameworks.

关键词： UAV GNSS Localization Precision Comparative GIS

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Organization of microtubule plus-end dynamics by phase separation in mitosis

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Journal of Molecular Cell Biology 2024年第2期16卷 24-35页

作者： Fengrui Yang Mingrui Ding Xiaoyu Song Fang Chen Tongtong Yang Chunyue Wang Chengcheng Hu Qing Hu Yihan Yao Shihao Du phil YYao Peng Xia Gregory Adams Jr Chuanhai Fu Shengqi Xiang Dan Liu Zhikai Wang Kai Yuan Xing Liu MOE Key Laboratory for Membraneless Organelles&Cellular Dynamics Hefei National Research Center for Cross-disciplinary SciencesCenter for Advanced Interdisciplinary Science and Biomedicine of IHMDivision of Life Sciences and MedicineUniversity of Science&Technology of ChinaHefei 230027China Anhui Key Laboratory for Cellular Dynamics and Chemical Biology University of Science&Technology of ChinaHefei 230027China Keck Center for Organoids Plasticity Morehouse School of MedicineAtlantaGA 30310USA Hunan Key Laboratory of Molecular Precision Medicine Central South UniversityChangsha 410083China

In eukaryotes,microtubule polymers are essential for cellular plasticity and fate ***-binding(EB)proteins serve as scaffolds for orchestrating microtubule polymer dynamics and are essential for cellular dynamics and chromosome segregation in ***,we show that EB1 forms molecular condensates with TIP150 and MCAK through liquid–liquid phase separation to compartmentalize the kinetochore–microtubule plus-end machinery,ensuring accurate kinetochore–microtubule interactions during chromosome segregation in *** of EB1–TIP150 polymer formation by a competing peptide prevents phase separation of the EB1-mediated complex and chromosome alignment at the metaphase equator in both cultured cells and Drosophila ***220 of EB1 is dynamically acetylated by p300/CBP-associated factor in early mitosis,and persistent acetylation at Lys220 attenuates phase separation of the EB1-mediated complex,dissolves droplets in vitro,and harnesses accurate chromosome *** data suggest a novel framework for understanding the organization and regulation of eukaryotic spindle for accurate chromosome segregation in mitosis.

关键词： phase separation mitosis microtubule dynamics EB1 acetylation

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运用18世纪的技术突破21世纪凸版印刷实验的界限

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装饰 2024年第2期 56-67页

作者： [英]高云飞汪芸密德萨斯大学《装饰》

高云飞是一位屡获殊荣的平面设计师、作家和艺术家。他的个性是在伦敦这个迷宫般的城市中形成的,同时,也受到了朋克、远东文化以及一些设计行业最著名和最有影响力的领导者的影响。他是安东尼·弗罗肖格的弟子。自1977年开始,他分别在... 详细信息

高云飞是一位屡获殊荣的平面设计师、作家和艺术家。他的个性是在伦敦这个迷宫般的城市中形成的,同时,也受到了朋克、远东文化以及一些设计行业最著名和最有影响力的领导者的影响。他是安东尼·弗罗肖格的弟子。自1977年开始,他分别在五角设计公司的艾伦·弗莱彻、荷兰TD的维姆·克劳维尔以及沃利·奥林斯设计事务所的迈克尔·沃尔夫的指导下磨练了自己的设计和排版技巧。目前,他运营着etal设计顾问公司。这是一家专业品牌代理机构,已创建了130多个品牌,其中包括在全球范围内为Visa重塑品牌,并以绘制Visa标识而知名。同时,他是伦敦密德萨斯大学创意产业专业的教授。他在世界各地举办有关创造力和设计的讲座,其早期的印刷作品存档于圣布莱德印刷图书馆(St Bride’s Printing Library)。他的书籍设计被V&A博物馆国家艺术图书馆(National Art Library)永久收藏。本文记录了高云飞近年来的实验性探索作品《我所挚爱的版式设计、字体与诗歌》,回溯了该作品与其45年前所做的金属手工字体实验之间的历史渊源,就版式和网格中的字体形式和结构系统的解构与重建进行了深入的探讨,并阐释了如何运用18世纪的技术突破21世纪凸版印刷实验的界限。

关键词：版式设计设计事务所高云飞艾伦平面设计师沃尔夫书籍设计弗莱彻

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基于多光谱图像的小麦种子形态和成分性状的自动化检测算法开发

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植物生理学报 2024年第4期60卷 739-752页

作者：李鸿岩戴杰周洁闻桢杰 phil Howell 周济南京农业大学前沿交叉研究院/工学院/作物表型组学交叉研究中心南京210095 英国国立农业植物研究所/剑桥作物研究中心英国剑桥CB3OLE

在全球气候变化加剧的背景下,小麦(Triticum aestivum)产量与中国粮食安全密切相关,因此,基于小麦种子外部形态与内部成分的快速、无损检测对高通量鉴定其品质和活力意义重大。针对当前种子检测通量及准确性的限制,本研究通过多学科融合... 详细信息

在全球气候变化加剧的背景下,小麦(Triticum aestivum)产量与中国粮食安全密切相关,因此,基于小麦种子外部形态与内部成分的快速、无损检测对高通量鉴定其品质和活力意义重大。针对当前种子检测通量及准确性的限制,本研究通过多学科融合,结合多光谱成像、计算机视觉、自动化图像处理等技术,开发了一种通过多光谱图像从近百粒种子中快速提取单粒、并在单粒尺度完成外部形态(如种子面积、长度、宽度与圆度等)和内部物质成分(如植物色素、淀粉、植物油脂与水分含量等)量化分析的算法。针对所选的15个小麦品种,算法对1 347粒种子形态性状的分析结果与人工测量结果间的决定系数(R2)为面积0.900 (RMSE=1.504)、长度0.981 (RMSE=0.188)、宽度0.911 (RMSE=0.795);对513粒种子的六个关键光谱波段的R2为0.973、0.970、0.983、0.953、0.891、0.893;以上P值均小于0.005。在此基础上,通过形态与光谱性状的聚类和主成分分析,本研究还构建了区分不同品种小麦种子的分类方法,进而探索了重要种子农艺性状(如种子破损区域及种胚检测等)的自动鉴选算法,为种子活力和品质的高通量检测研究提供了新思路和新方法。

关键词：种子形态分析种子成分表征多光谱成像技术自动化图像处理小麦

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