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Dry eye rate and its relationship with disease stage in patients with primary hypertension:a cross-sectional study in Vietnam

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 653-658页

作者： Tran Tat Thang pham hong phuong Nguyen Sa Huynh Nguyen Trung Kien NguyenDuy Toan Nguyen Thi Thu Ha Le Ha Khoa Nguyen Huu Dung Thai Doan Thang Le Viet Thang Nghe An Eye Hospital Nghe An 43000Vietnam Nghe An Friendship General Hospital Nghe An 43000Vietnam Military Hospital 103 Ha Noi 100000Vietnam Vietnam Military Medical University Ha Noi 100000Vietnam Hanoi Medical University Ha Noi 100000Vietnam Bạch Mai Hospital Ha Noi 100000Vietnam TTH Vinh General Hospital Nghe An 100000Vietnam

AIM:To determine the dry eye(DE)rate and its relationship with disease stage in patients with primary ***:A cross-sectional study included 432 patients with primary hypertension(with an equal number of patients in each group:144 in stage Ⅰ,Ⅱ,and Ⅲ hypertension)and 144 healthy subjects as a control *** Ocular Surface Disease Index(OSDI)and Schirmer Ⅰ test without anesthetics were conducted on all 576 *** with OSDI scores<13 and Schirmer Ⅰ values equal to or under 10 mm were diagnosed with ***:The ratio of DE in hypertension patients was higher than in the control group(41.7%versus 18.8%;P<0.001).The proportion of patients with DE increased gradually according to the hypertension stage:27.1% in stage Ⅰ,40.3% in stage Ⅱ,and 57.6% in stage Ⅲ,P<***,duration of hypertension,plasma urea,creatinine,and high-sensitivity C-reactive protein(CRP-hs)levels in hypertension patients with DE were higher than those without DE,P<*** age,a long duration of hypertension,diabetes mellitus,elevated plasma creatinine,and CRP-hs levels were independent factors associated with DE in primary hypertension patients,P<***:DE is a common disorder associated with advanced age,a long duration of hypertension,diabetes mellitus,elevated plasma CRP-hs,and creatinine levels in patients with primary hypertension.

关键词： primary hypertension dry eye stage of hypertension plasma creatinine

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电针镇痛在甲状腺全切除术中控制术中疼痛和血流动力学的有效性和安全性：一项随机对照试验（英文）

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Journal of Traditional Chinese Medical Sciences 2024年第2期11卷 165-171页

作者： Tran,Dong phuong Nguyen,Quoc Dung Nguyen,Ninh Khac pham,Van hong Senior Specialist Clinic National Hospital of Acupuncture Vietnam National Association of Acupuncture Department of Training and Science National Hospital of Acupuncture

目的：评价电针联合其他药物在甲状腺全切除术中提供镇痛和稳定血流动力学参数的有效性和安全性。方法：该随机对照试验囊括了100例患者，这些患者于2022年10月至2023年10月在越南国立针灸医院接受了甲状腺全切除术。患者被随机分为了... 详细信息

目的：评价电针联合其他药物在甲状腺全切除术中提供镇痛和稳定血流动力学参数的有效性和安全性。方法：该随机对照试验囊括了100例患者，这些患者于2022年10月至2023年10月在越南国立针灸医院接受了甲状腺全切除术。患者被随机分为了两组。电针镇痛组（EA）对合谷穴（LI 4）、内关穴（PC 6）、水突穴（ST 10）、缺盆穴（ST 12）、翳风穴（SJ 17）5个穴位进行了电针刺激，对照组患者进行了双侧浅表颈丛神经阻滞。主要结局包括两组患者的镇痛水平和围手术期生命体征。此外，测定了EA组患者电针前后的疼痛阈值和血清β-内啡肽水平。结果：EA组和对照组分别有86%和76%的患者达到完全镇痛（A级），两组间无显著差异（P=1.00）。EA组患者接受EA后平均疼痛阈值翻倍（648.7(77.4) g/s vs. 305.3 (45.3) g/s, P <0.001），平均血清β-内啡肽水平增加了约13.5pg/m L(P <0.001)。所有患者在整个手术过程中的血流动力学维持稳定。结论：EA联合其他药物刺激了5个穴位，LI 4、PC 6、ST 10、ST 12和SJ 17，在甲状腺全切除术中耐受良好，有效地维持了适当的镇痛水平和血流动力学稳定性。

关键词：电针针灸镇痛格雷夫斯病甲状腺切除术甲状腺手术 β-内啡肽

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Influence of different land-use types on selected soil properties related to soil fertility in A Luoi District,Thua Thien Hue,Vietnam

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Soil Ecology Letters 2024年第1期6卷 131-140页

作者： Khoa Phuc Nguyen Tan Trong Tran Huy Dinh Le phuong Thuy Nguyen Hien Thao Thi pham Dien Thanh Nguyen Ngu Huu Nguyen University of Agriculture and Forestry Hue UniversityHue CityThua Thien Hue 52000Vietnam School of Biotechnology Tan Tao UniversityTan Duc ECityDuc HoaLong An850000Vietnam

Land use type affects the physicochemical properties of *** value of OM and TN is high in acacia *** acidity of soil is considered a serious constraint for *** cash crops are acacia,cassava,banana,rice and *** fertility is affected by land-use types and land management,which exacerbates soil erosion and various other forms of soil degradation in the mountainous regions of *** study was conducted in A Luoi District,Thua Thien Hue,Vietnam to identify the effects of land-use types on specific soil physicochemical characteristics related to soil *** physicochemical properties,such as organic matter(OM),total nitrogen(TN),total phosphorous(TP),and K+were significantly affected by land-use *** results showed that the soils were sandy in rice but clay loam for acacia and *** mean bulk density value of acacia soil was significantly greater than that of other *** were higher in the acacia soils than those in the rice,maize,and banana *** OM content was significantly higher in the acacia,cassava,and banana soils than those in the rice and maize *** mean of exchangeable K+in the rice soil was higher compared to those in other soils and was affected by land-use *** high exchangeable acidity content in the soils was probably due to intensive ***,both land use type and management did not affect the CEC ***,the inappropriate land use caused the disturbance of soil physicochemical properties,indicating that the conditions of rice and maize soils are becoming worse than acacia ***,lowering the intensity of cultivation,adopting incorporated soil fertility management,and applying organic fertilizer should preserve the existing conditions and enhance soil properties.

关键词： Land-use types soil characteristics soil frility suitable crop Vietnam

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Improving Supply Chain Performance Through Supplier Selection and Order Allocation Problem

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Computers, Materials & Continua 2022年第1期70卷 1667-1681页

作者： Chia-Nan Wang Ming-Cheng Tsou Chih-Hung Wang Viet Tinh Nguyen pham Ngo Thi phuong Department of Industrial Engineering and Management National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Department of Shipping Technology National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Department of International Business Shih Chien UniversityTaipei80778Taiwan Faculty of Commerce Van Lang UniversityHo Chi Minh City70000Vietnam Faculty of Industrial Engineering and Management International UniversityHo Chi Minh City70000Vietnam

Suppliers play the vital role of ensuring the continuous supply of goods to themarket for *** businesses do not maintain a strong bond with their suppliers,they may not be able to secure a steady supply of goods and products for their *** a result of failure to deliver products,the production and business activities of the business can be delayed which leads to the loss of ***,each trading enterprise will have a variety of commodity supply chains withmultiple *** play an important role and contribute to the value of the entire supply *** any supplier encounters a problem,the whole supply chain of businesses will be affected and could lead to not guaranteeing the stable supply to the ***,suppliers can be seen as a threat to businesses where they have the ability to increase input prices or decrease the quality of the required products and services they *** quantity of the business,and the supply lead time directly affect the operations and reduce the profitability of the *** paper mainly focuses on the supplier selection problemunder a variety of price level and product families when using a two-phase fuzzy multi-objective linear *** objectives of the proposed model are to minimize the total purchasing and ordering cost in order to reduce the quantity of defective materials and the late-delivery components from ***,the piecewise linear membership function is applied in themodel to determine an optimal solution which is based on the requirement of decision makers under their fuzzy *** results of this study can be applied in various business environment and provide a reliable decision tool for choosing potential suppliers relating to these *** on the results,the company canmake a good decision on supplier selection;therefore,the company can improve the quality and quantity of their final *** is because,the best supplier can su

关键词： Supplier selection multi-objective linear programming multiprice level multi-product fuzzy sets

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Embryonic, genetic and clinical outcomes of fresh versus vitrified oocyte: A retrospective cohort study

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Asian pacific Journal of Reproduction 2023年第6期12卷 266-272页

作者： phuong Dao Thi Son Dang Truong Thuan Nguyen Duc Anh pham Van Anh Do Tuan Van Hanh Nguyen HP Fertility-Hai Phong International Hospital of Obstetrics and Pediatrics Haiphong180000Vietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoi100000Vietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoi100000Vietnam

Objective:To compare embryonic development,ploidy status and clinical outcomes between fresh and frozen-thawed ***:This retrospective cohort study evaluated 83 fertilization cycles including both fresh and frozen oocytes from 79 patients at the HP Fertility Center of Hai Phong International Hospital of Obstetrics and Pediatrics in *** patient underwent several ovarian stimulation cycles to accumulate a certain number of oocytes that would be *** the last oocyte retrieval,all patient’s oocytes including both frozen and fresh would be *** outcomes included the rates of oocyte survival,cleavage embryo,blastocyst,ploidy status,pregnancy,biochemical pregnancy and clinical ***:The oocyte survival rate after thawing was 96.5%.No statistically significant difference was found when comparing fresh and frozen oocytes regarding fertilization rate(78.1%vs.75.5%,P=0.461),usable cleavage embryo rate(86.9%vs.87.2%,P=0.916)but usable blastocyst rate was found higher statistically in the frozen oocyte group(44.4%vs.54.0%,P=0.049).The percentages of euploid,aneuploid and mosaic embryos between the fresh group and the vitrified group had no significant differences(33.8%vs.31.6%,P=0.682;51.0%vs.54.2%,P=0.569;15.2%vs.12.4%,P=0.787;respectively).The rates of pregnancy,biochemical pregnancy and clinical pregnancy had no statistical difference(68.8%vs.64.8%,P=0.764;12.5%vs.3.6%,P=0.258;37.5%vs.46.4%,P=0.565).17 Mature oocytes are the minimum to have at least one euploid ***:Oocyte vitrification does not affect embryonic,genetic and clinical *** number of mature oocytes should be considered for fertilization in some cases.

关键词： Clinical outcomes Embryonic development Genetic outcomes Human oocyte Oocyte accumulation Oocyte cryopreservation Ploidy status Vitrified oocyte

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Morphology and kinematics of the gas envelope of the Mira binary W Aquilae

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Research in Astronomy and Astrophysics 2016年第7期16卷 47-54页

作者： Do Thi Hoai pham Tuyet Nhung pham Ngoc Diep Nguyen Thi phuong pham Tuan-Anh Nguyen Thi Thao Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

We analyse ALMA observations of the12CO（3-2） emission of the circumstellar envelope（CSE）of the Mira variable binary star W Aql. These provide, for the first time, spatially resolved Doppler velocity spectra of the CSE up to angular distances to the central star ofy nature of the observations（only five minutes in each of～5′′（meaning some 2000 AU）. The explorator two different configurations） does not allow for a detailed modelling of the properties of the CSE but provides important qualitative information on its morphology and kinematics. Emission is found to be enhanced along an axis moving from east/west to north-east/south-west when the angular distance from the central star projected on the plane of the sky increases from zero to four arcseconds. In parallel, the Doppler velocity distribution displays asymmetry along an axis moving from east/west to north-west/south-east. The results are discussed in the context of earlier observations, in particular of the dust morphology.

关键词： stars AGB and post-AGB (stars ) circumstellar matter stars individual(W Aql) stars mass-loss radio lines stars

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Stem cell-based therapy for human diseases

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Signal Transduction and Targeted Therapy 2022年第9期7卷 3242-3282页

作者： Duc M.Hoang phuong T.pham Trung Q.Bach Anh T.L.Ngo Quyen T.Nguyen Trang T.K.Phan Giang H.Nguyen phuong T.T.Le Van T.Hoang Nicholas R.Forsyth Michael Heke Liem Thanh Nguyen Department of Research and Development Vinmec Research Institute of Stem Cell and Gene TechnologyVinmec Healthcare SystemHanoiVietnam Department of Cellular Therapy Vinmec High.Tech CenterVinmec Healthcare SsystemHanoiVietnam Institute for Science&Technology in Medicine Keele UniversityKeeleUK a Department of Biology Stanford UniversityStanfordCAUSA

Recent advancements in stem cell technology open a new door for patients suffering from diseases and disorders that have yet to be *** cell-based therapy,including human pluripotent stem cells(hPsCs)and multipotent mesenchymal stem cells(MSCs),has recently emerged as a key player in regenerative *** are defined as self-renewable cell types conferring the ability to differentiate into various cellular phenotypes of the human body,including three germ *** are multipotent progenitor cells possessing self-renewal ability(limited in vitro)and differentiation potential into mesenchymal lineages,according to the International Society for Cell and Gene Therapy(ISCT).This review provides an update on recent clinical applications using either hPSCs or MSCs derived from bone marrow(BM),adipose tissue(AT),or the umbilical cord(UC)for the treatment of human diseases,including neurological disorders,pulmonary dysfunctions,metabolic/endocrine-related diseases,reproductive disorders,skin burns,and cardiovascular ***,we discuss our own clinical trial experiences on targeted therapies using MsCs in a clinical setting,and we propose and discuss the MSC tissue origin concept and how MSC origin may contribute to the role of MSCs in downstream applications,with the ultimate objective of facilitating translational research in regenerative medicine into clinical *** mechanisms discussed here support the proposed hypothesis that BM-MSCs are potentially good candidates for brain and spinal cord injury treatment,AT-MSCs are potentially good candidates for reproductive disorder treatment and skin regeneration,and UC-MsCs are potentially good candidates for pulmonary disease and acute respiratory distress svndrometreatment.

关键词： diseases distress treatment

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^(12)CO emission from the Red Rectangle

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Research in Astronomy and Astrophysics 2015年第12期15卷 2213-2228页

作者： pham Tuan Anh pham Ngoc Diep Do Thi Hoai pham Tuyet Nhung Nguyen Thi phuong Nguyen Thi Thao Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

Observations of an unprecedented quality made by ALMA on the Red Rectangle of CO（3-2） and CO（6-5） emissions are analysed jointly with the aim of obtaining as simple as possible a description of the gas morphology and kinematics. Evidence is found for polar conical outflows and for a broad equatorial torus in rotation and expansion. Simple models of both are proposed. Comparing CO（6-5） and CO（3-2） emissions provides evidence for a strong temperature enhancement over the polar outflows. Continuum emission （dust） is seen to be enhanced in the equatorial region. Observed asymmetries are briefly discussed.

关键词： stars: AGB and post-AGB -- circumstellar matter -- radio-lines: stars-- planetary nebulae: individual (Red Rectangle)

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Morphology and kinematics of the gas envelope of the variable AGB star π^1 Gruis

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Research in Astronomy and Astrophysics 2016年第7期16卷 97-104页

作者： pham Tuyet Nhung Do Thi Hoai pham Ngoc Diep Nguyen Thi phuong Nguyen Thi Thao pham Tuan Anh Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

Observations of the ^12CO（3–2） emission from the circumstellar envelope（CSE） of the variable star π1Gru using the compact array of the ALMA observatory have been recently made accessible to the public. An analysis of the morphology and kinematics of the CSE is presented with a result very similar to that obtained earlier for ^12CO（2–1） emission using the Submillimeter Array. A quantitative comparison is made using their flared disk model. A new model is presented that provides a significantly better description of the data, using radial winds and smooth evolutions of the radio emission and wind velocity from the stellar equator to the poles.

关键词： stars AGB and post-AGB circumstellar matter star individual(π1Gru) stars massloss radio lines stars

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ALMA observations of the circumstellar envelope around EP Aqr

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Research in Astronomy and Astrophysics 2019年第3期19卷 97-110页

作者： pham Thi Tuyet Nhung Do Thi Hoai pham Tuan-Anh Thibaut Le Bertre Pierre Darriulat pham Ngoc Diep Nguyen Thi phuong Nguyen Thi Thao Jan Martin Winters Department of Astrophysics Vietnam National Space CenterVAST LERMA UMR 8112 CNRS and Observatoire de Paris PSL Research University Graduate University of Science and Technology VAST IRAM 300 rue de la Piscine Domaine Universitaire

Atacama Large Millimetre/sub-millimetre Array(ALMA) observations of CO(1–0) and CO(2–1) emissions from the circumstellar envelope of the asymptotic giant branch(AGB) star EP Aqr have been made with four times better spatial resolution than previously available. They are analysed with emphasis on the de-projection in space of the effective emissivity and flux of matter using as input a prescribed configuration of the velocity field, assumed to be radial. The data are found to display an intrinsic axisymmetry with respect to an axis making a small angle with respect to the line of sight. A broad range of wind configurations, from prolate(bipolar) to oblate(equatorial) has been studied and found to be accompanied by significant equatorial emission. Qualitatively, the effective emissivity is enhanced near the equator to produce the central narrow component observed in the Doppler velocity spectra and its dependence on star latitude generally follows that of the wind velocity with the exception of an omni-present depression near the poles. In particular, large equatorial expansion velocities produce a flared disc or a ring of effective emissivity and mass loss. The effect on the determination of the orientation of the star axis of radial velocity gradients, and possibly competing rotation and expansion in the equatorial disc, is discussed. In general,the flux of matter is found to reach a broad maximum at distances of the order of 500 AU from the *** are given that may be used to favour one wind velocity distribution over another. As a result of the improved quality of the data, a deeper understanding of the constraints imposed on morphology and kinematics has been obtained.

关键词： stars: AGB and post-AGB (stars:) circumstellar matter stars: individual: EP Aqr stars:mass-loss radio lines: stars

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