Dry eye rate and its relationship with disease stage in patients with primary hypertension:a cross-sectional study in Vietnam
作者机构:Nghe An Eye HospitalNghe An 43000Vietnam Nghe An Friendship General HospitalNghe An 43000Vietnam Military Hospital 103Ha Noi 100000Vietnam Vietnam Military Medical UniversityHa Noi 100000Vietnam Hanoi Medical UniversityHa Noi 100000Vietnam Bạch Mai HospitalHa Noi 100000Vietnam TTH Vinh General HospitalNghe An 100000Vietnam
出 版 物:《International Journal of Ophthalmology(English edition)》 (国际眼科杂志(英文版))
年 卷 期:2024年第17卷第4期
页 面:653-658页
核心收录:
学科分类:1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
主 题:primary hypertension dry eye stage of hypertension plasma creatinine
摘 要:AIM:To determine the dry eye(DE)rate and its relationship with disease stage in patients with primary ***:A cross-sectional study included 432 patients with primary hypertension(with an equal number of patients in each group:144 in stage Ⅰ,Ⅱ,and Ⅲ hypertension)and 144 healthy subjects as a control *** Ocular Surface Disease Index(OSDI)and Schirmer Ⅰ test without anesthetics were conducted on all 576 *** with OSDI scores13 and Schirmer Ⅰ values equal to or under 10 mm were diagnosed with ***:The ratio of DE in hypertension patients was higher than in the control group(41.7%versus 18.8%;P0.001).The proportion of patients with DE increased gradually according to the hypertension stage:27.1% in stage Ⅰ,40.3% in stage Ⅱ,and 57.6% in stage Ⅲ,P***,duration of hypertension,plasma urea,creatinine,and high-sensitivity C-reactive protein(CRP-hs)levels in hypertension patients with DE were higher than those without DE,P*** age,a long duration of hypertension,diabetes mellitus,elevated plasma creatinine,and CRP-hs levels were independent factors associated with DE in primary hypertension patients,P***:DE is a common disorder associated with advanced age,a long duration of hypertension,diabetes mellitus,elevated plasma CRP-hs,and creatinine levels in patients with primary hypertension.