检索结果-南通市图书馆

An Interview with peter Deadman—Acupuncture Pioneer and Founder of The Journal of Chinese Medicine

在线全文

学校读者我要写书评

暂无评论

Chinese Medicine and Culture 2024年第1期7卷 19-28页

作者： Ioannis Solos Charles Buck peter Deadman Saint george Clinic and Research Institute Scottsdale 85251the United States of America Northern College of Acupuncture Micklegate YO16LJthe United Kingdom British Acupuncture Council London W129HQthe United Kingdom The Register of Chinese Herbal Medicine London WC1N 3GSthe United Kingdom

This interview was conducted on August 21st, 2022 by Charles Buck and Ioannis Solos. peter Deadman has worked in the field of health promotion for 50 years. He co-founded Infinity Foods(an organic and natural foods workers co-op) in 1971, followed by the Brighton Natural Health Centre-a charity dedicated to teaching ways to improve personal, community and planetary health and wellbeing. He qualified as an acupuncturist in 1978 and in Chinese herbal medicine in 1990. He founded The Journal of Chinese Medicine(UK) in 1979(Fig. 1), and co-authored A Manual of Acupuncture(published in 1998). He is the author of Live Well Live Long: Teachings from the Chinese Nourishment of Life Tradition. He has taught Chinese medicine and health promotion internationally for decades and is a dedicated practitioner and teacher of Qi gong(气功).

关键词： Acupuncture Medicine herbal

Experimental investigation on slip conditions during thread rolling with flat dies

在线全文

学校读者我要写书评

暂无评论

Friction 2024年第1期12卷 136-143页

作者： Stefan VOLZ peter gROCHE Institute for Production Engineering and Forming Machines Technical University DarmstadtOtto-Berndt Straße 2Darmstadt 64287Germany

The process design of flat die rolling operations can be a tedious and costly process due to the challenges posed by small process *** this work,an effort is made to closely investigate and understand the process limits caused by excessive slippage of the *** measurements are carried out to capture the characteristics of excessive slippage and the influence of the stroke rate and the tribological system on this process *** differences in slippage were observed,depending on the tribological *** systems with polymer based lubricants showed excessive slippage at low stroke rates,systems using oil or no lubricant endured higher stroke rates before process limits were *** optical measurements revealed three major forms of slippage:successful rolling without slippage,failure due to excessive slippage at process start,and failure due to excessive slippage at around one workpiece rotation.

关键词： rolling incremental forming thread rolling slippage profile rolling

Highly-sensitive wafer-scale transfer-free graphene MEMS condenser microphones

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microsystems & Nanoengineering 2024年第1期10卷 267-275页

作者： Roberto Pezone Sebastian Anzinger gabriele Baglioni Hutomo Suryo Wasisto Pasqualina M.Sarro peter g.Steeneken Sten Vollebregt Laboratory of Electronic Components Technology and Materials(ECTM)Department of MicroelectronicsDelft University of TechnologyDelftThe Netherlands Infineon Technologies Ag Am Campeon 1-15Neubiberg 85579Germany Kavli Institue of Nanoscience Department of Quantum NanoscienceDelft University of TechnologyDelftthe Netherlands Department of Precision and Microsystems Engineering(PME) Delft University of TechnologyDelftThe Netherlands

Since the performance of micro-electro-mechanical system(MEMS)-based microphones is approaching fundamental physical,design,and material limits,it has become challenging to improve *** works have demonstrated graphene’s suitability as a microphone *** potential for achieving smaller,more sensitive,and scalable onchip MEMS microphones is yet to be *** address large graphene sizes,graphene-polymer heterostructures have been proposed,but they compromise performance due to added polymer mass and *** work demonstrates the first wafer-scale integrated MEMS condenser microphones with diameters of 2R=220-320μm,thickness of 7 nm multi-layer graphene,that is suspended over a back-plate with a residual gap of 5μ*** microphones are manufactured with MEMS compatible wafer-scale technologies without any transfer steps or polymer layers that are more prone to contaminate and wrinkle the *** designs,all electrically integrated are fabricated and characterized allowing us to study the effects of the introduction of a back-plate for capacitive *** devices show high mechanical compliances C_(m)=0.081-1.07μmPa^(−1)(10-100×higher than the silicon reported in the state-of-the-art diaphragms)and pull-in voltages in the range of 2-9.5 *** addition,to validate the proof of concept,we have electrically characterized the graphene microphone when subjected to sound *** estimated sensitivity of S_(1kHz)=24.3-321 mV Pa^(−1)for a V_(bias)=1.5 V was determined,which is 1.9-25.5×higher than of state-of-the-art microphone devices while having a~9×smaller area.

关键词： transfer plate approaching

Organochlorides Mediate Oxidation Reactions Induced by Low Dose Ionizing Radiation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CCS Chemistry 2024年第7期6卷 1712-1720页

作者： Juncheng Liu Tobias g.Brevé Bing Xu peter-Leon Hagedoorn Antonia g.Denkova Rienk Eelkema Department of Radiation Science and Technology Delft University of Technology2629 JB Delft Department of Chemical Engineering Delft University of Technology2629 HZ Delft Department of Biotechnology Delft University of Technology2629 HZ Delft

The controlled release of drugs using local ionizing radiation presents a promising approach for targeted cancer treatment,particularly when applied in concurrent *** these approaches,radiation-generated reactive species often play an important ***,the reactive species that can be used to trigger release have low yield and lack ***,we demonstrate the generation of highly oxidative species when aqueous solutions containing low concentrations of organochlorides(such as chloroform)are irradiated with ionizing radiation at therapeutically relevant *** reactive species were identified as peroxyl radicals,which formed in a reaction cascade between organochlorides and aqueous *** employed stilbene-based probes to investigate the oxidation process,showing double bond oxidation and *** translate this reactivity into a radiation-sensitive material,we synthesized a micelle-forming amphiphilic block copolymer that has stilbene as the linker between two *** exposure to ionizing radiation,the oxidation of stilbene led to the cleavage of the polymer,which induces the dissociation of the block-copolymer micelles and the release of loaded drugs.

关键词： drug delivery micelles radiation chemistry reactive oxygen species ionizing radiation reaction mechanisms

Skeletal muscle as a molecular and cellular biomarker of disease progression in amyotrophic lateral sclerosis:a narrative review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第4期19卷 747-753页

作者： peter H.King Department of Neurology and Center for Neurodegeneration and Experimental Therapeutics The University of Alabama at BirminghamBirminghamALUSA Birmingham Veterans Affairs Medical Center BirminghamALUSA

Amyotrophic lateral sclerosis is a fatal multisystemic neurodegenerative disease with motor neurons being a primary *** progressive weakness is a hallmark feature of amyotrophic lateral sclerosis,there is considerable heterogeneity,including clinical presentation,progression,and the underlying triggers for disease *** on longitudinal studies with families harboring amyotrophic lateral sclerosis-associated gene mutations,it has become apparent that overt disease is preceded by a prodromal phase,possibly in years,where compensatory mechanisms delay symptom *** 85-90%of amyotrophic lateral sclerosis is sporadic,there is a strong need for identifying biomarkers that can detect this prodromal phase as motor neurons have limited capacity for *** Food and Drug Administration-approved therapies work by slowing the degenerative process and are most effective early in the *** muscle,including the neuromuscular junction,manifests abnormalities at the earliest stages of the disease,before motor neuron loss,making it a promising source for identifying biomarkers of the prodromal *** accessibility of muscle through biopsy provides a lens into the distal motor system at earlier stages and in real *** advent of“omics”technology has led to the identification of numerous dysregulated molecules in amyotrophic lateral sclerosis muscle,ranging from coding and non-coding RNAs to proteins and *** technology has opened the door for identifying biomarkers of disease activity and providing insight into disease mechanisms.A major challenge is correlating the myriad of dysregulated molecules with clinical or histological progression and understanding their relevance to presymptomatic phases of *** are two major goals of this *** first is to summarize some of the biomarkers identified in human amyotrophic lateral sclerosis muscle that have a clinicopathological correlation with disease activi

关键词： amyotrophic lateral sclerosis biomarkers clinicopathological correlation disease progression muscle biomarkers neurogenic atrophy neuromuscular junction non-coding RNAs presymptomatic stages skeletal muscle SOD1g93A mouse model

A product version of the Hilton-Milner-Frankl theorem

在线全文

学校读者我要写书评

暂无评论

Science China Mathematics 2024年第2期67卷 455-474页

作者： peter Frankl Jian Wang Alfréd Rényi Institute of Mathematics Hungarian Academy of SciencesBudapest H-1053Hungary Department of Mathematics Taiyuan University of TechnologyTaiyuan 030024China

Two families F and g of k-subsets of {1, 2,..., n} are called non-trivial cross t-intersecting if|F ∩ g|≥t for all F ∈ F, g ∈ g and | ∩ {F : F ∈ F}| < t, | ∩ {g : g ∈ g}| < t. In the present paper,we determine... 详细信息

Two families F and g of k-subsets of {1, 2,..., n} are called non-trivial cross t-intersecting if|F ∩ g|≥t for all F ∈ F, g ∈ g and | ∩ {F : F ∈ F}| g : g ∈ g}| g families of k-subsets of{1, 2,..., n} for n≥4(t + 2)2k2, k≥5, which is a product version of the Hilton-Milner-Frankl theorem.

关键词： extremal set theory cross t-intersecting family product version non-trivial

A Population Dynamics Approach to the Distribution of Space Debris in Low Earth Orbit

在线全文

学校读者我要写书评

暂无评论

Communications on Applied Mathematics and Computation 2024年第1期6卷 340-353页

作者： John Jurkiewicz peter Hinow Department of Mathematical Sciences University of Wisconsin-MilwaukeeMilwaukeeWI53201USA

The presence of the debris in the Earth’s orbit poses a significant risk to human activity in outer *** debris population continues to grow due to ground launches,the loss of external parts from space ships,and uncontrollable collisions between objects.A computationally feasible continuum model for the growth of the debris population and its spatial distribution is therefore *** we propose a diffusion-collision model for the evolution of the debris density in the low-Earth orbit and its dependence on the ground-launch *** parametrize this model and test it against data from publicly available object catalogs to examine timescales for the uncontrolled ***,we consider sensible launch policies and cleanup strategies and how they reduce the future risk of collisions with active satellites or space ships.

关键词： Population dynamics Space debris Kessler syndrome Diffusion Low-Earth orbit

Diagnostic tools for fecal incontinence: Scoring systems are the crucial first step

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of gastroenterology 2024年第6期30卷 516-522页

作者： peter Liptak Martin Duricek peter Banovcin Clinic of Internal Medicine-gastroenterology University Hospital in MartinJessenius Faculty of Medicine in MartinComenius UniversityMartin 03601Slovakia

The main aim of this editorial is to comment on the recent article published by garg et al in the World Journal of gastroenterology 2023;29:*** original research presents a new scoring system for fecal *** incontinence is a chronic disease with a severe impact on the quality of life of the *** social stigmatization often leads to significant underreporting of the condition even during visits to a specialist and could lead to further misman-agement or non-existent management of the *** important fact is that patients are often unable to describe their condition when not asked precisely defined *** problem is partially resolved by scoring *** scoring systems are commonly used;however,each of them has their *** example,the absence of different kinds of leakage besides flatus and stool could further lead to underscoring the incontinence ***,there has long been a call for a more precise scoring *** correct identification of the presence and severity of fecal incontinence is paramount for further diagnostic approach and for choosing the appropriate therapy *** editorial describes fecal incontinence,its effect on quality of life in general and further evaluates the diagnostic approach with a particular focus on symptom scoring systems and their implications for clinical practice.

关键词： Incontinence Fecal Scoring system Questionary Quality of life

Identific tion of quantitative trait loci and associated candidate genes for pregnancy success in Angus–Brahman crossbred heifers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2024年第1期15卷 162-170页

作者： Quinn A.Hoorn gabriel A.Zayas Eduardo E.Rodriguez Laura M.Jensen Raluca g.Mateescu peter J.Hansen Department of Animal Sciences Donald Henry Barron Reproductive and Perinatal Biology Research Programand the Genetics InstituteUniversity of FloridaGainesvilleFLUSA School of Applied Systems Biology La Trobe UniversityBundooraVIC 3083Australia

Background In beef cattle, more than 50% of the energy input to produce a unit of beef is consumed by the female that produced the calf. Development of genomic tools to identify females with high genetic merit for reproductive function could increase the profitability and sustainability of beef *** genome-wide association studies(gWAS) were performed using a single-step genomic best linear unbiased prediction approach on pregnancy outcome traits from a population of Angus–Brahman crossbred heifers. Furthermore, a validation gWAS was performed using data from another farm. Heifers were genotyped with the Bovine ggP F250 array that contains 221,077 SNPs. In the discovery population, heifers were bred in winter breeding seasons involving a single round of timed artificial insemination(AI) followed by natural mating for 3 months. Two phenotypes were analyzed: pregnancy outcome to first-service AI(PAI;n = 1,481) and pregnancy status at the end of the breeding season(PEBS;n = 1,725). The heritability was estimated as 0.149 and 0.122 for PAI and PEBS, respectively. In the PAI model, one quantitative trait locus(QTL), located between 52.3 and 52.5 Mb on BTA7, explained about 3% of the genetic variation, in a region containing a cluster of γ-protocadherin genes and SLC25A2. Other QTLs explaining between 0.5% and 1% of the genetic variation were found on BTA12 and 25. In the PEBS model, a large QTL on BTA7 was synonymous with the QTL for PAI, with minor QTLs located on BTA5, 9, 10, 11, 19, and 20. The validation population for pregnancy status at the end of the breeding season were Angus–Brahman crossbred heifers bred by natural mating. In concordance with the discovery population, the large QTL on BTA7 and QTLs on BTA10 and 12 were *** In summary, QTLs and candidate SNPs identified were associated with pregnancy outcomes in beef heifers, including a large QTL associated with a group of protocadherin genes. Confirmation of these associations

关键词： Beef cattle Fertility gWAS QTL