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Cork and Sustainability:Discussing the Sustainable Use of the Material from a Design Perspective

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Journal of Shanghai Jiaotong university(Science) 2012年第3期17卷 360-363页

作者： ana carina pereira HAN Brezet HELENA pereira JOOST Vogtlnder Design for Sustainability Faculty Industrial Design EngineeringDelft University of Technology2628 CE DelftThe Netherlands Forest Research Centre School of AgronomyTechnical University of LisbonLisbon 1349-017Portugal

There is the challenge to use materials in a more sustainable *** though cork has an interesting eco-profile as a material,other aspects contributing to an enhanced sustainable use of the resource are discussed:addres... 详细信息

关键词： sustainability design and materials cork products and materials eco-materials

Diet as an epigenetic factor in inflammatory bowel disease

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World Journal of Gastroenterology 2023年第41期29卷 5618-5629页

作者： Karina Marangoni Gilson Dorneles Daniella Miranda da Silva Letícia pereira Pinto carina Rossoni Sabrina Alves Fernandes Egas Moniz School of Health and Science Caparica-AlmadaPortugalCaparica 2820-062Portugal National Institute of Sciences and Technology-Theranostics and Nanobiotechnology Federal University of Uberlandia-MGBrazilUberlândia 38400-902Brazil Corporate Social Responsibility Hospital Moinhos de VentoPorto Alegre 90035-004Brazil Postgraduate Program in Gastroenterology Universidade Federal do Rio Grande do SulPorto Alegre 91540-000Brazil Department of Nutrition Uniasselvi-Group VitruSanta Catarina 89082-262Brazil Postgraduate Program in Hepatology Universidade Federal de Ciências da Saúde de Porto AlegrePorto Alegre 90050-170Brazil Master in Physical Activity and Health Polytechnic Institute of BejaBeja 7800-000Portugal Degree in Nutrition Sciences Lusófona UniversityLisboa 1749-024Portugal

Inflammatory bowel disease(IBD)has as a main characteristic the exacerbation of the immune system against enterocytes,compromising the individual’s intestinal *** inflammatory cascade causes several nutritional deficiencies,which further compromise immunological functioning and,as a result,worsen the *** vicious cycle can be interrupted as the patient’s dietary pattern meets their needs according to their clinical condition,acting directly on the inflammatory process of IBD through the interaction of food,intestinal microbiota,and *** nutritional intervention for IBD has a crucial role in preventing and managing disease *** review addresses epigenetic modifications through dietary compounds as a mechanism for modulating the intestinal microbiota of patients with IBD.

关键词： Inflammatory bowel disease Epigenetics Nutrition Nutrigenetics

Genoprotection and metabolic benefits of marine macroalgae-Insights into the concept of functional foods through direct and indirect consumption

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Food Bioscience 2022年第3期47卷 524-533页

作者： ana Marques João Ferreira ana Cerqueda-Pacheco Vitória pereira Helena Abreu Rui pereira Maria João Pires Fernanda Seixas Paula Oliveira Isabel Gaivão Mário Pacheco Laboratory of Physiotoxicology CESAM-Centre for Environmental and Marine StudiesDepartment of BiologyUniversity of AveiroCampus Universitário de Santiago3810-193AveiroPortugal CECAV-Animal and Veterinary Research Center AL4AnimalsUniversity of Trás-os-Montes and Alto DouroQuinta de Prados5000-801Vila RealPortugal Department of Genetics and Biotechnology University of Trás-os-Montes and Alto DouroQuinta de Prados5000-801Vila RealPortugal Department of Biology and Environment University of Trás-os-Montes and Alto DouroQuinta de Prados5000-801Vila RealPortugal CITAB-Centre for the Research and Technology of Agro-Environmental and Biological Sciences Inov4AgroUniversity of Trás-os-Montes and Alto DouroQuinta de Prados5000-801Vila RealPortugal Department of Veterinary Sciences University of Trás-os-Montes and Alto DouroQuinta de Prados5000-801Vila RealPortugal ALGAplus Lda.Travessa Alexandre da Conceição s/n3830-196ÍlhavoPortugal

The consumption of marine macroalgae has been linked with health benefits,albeit some actions,including genoprotection,remain ***,we evaluated the genoprotective potential of a mixture of Ulva rigida,Fucus vesiculosus and Gracilaria gracilis,through direct consumption or via indirect intake using fish(Sparus aurata)as a vector of algal ***(Mus musculus)were subjected to a 1-month dietary supplementation with 5%of macroalgae mix or 10%of fillet of fish previously fed with an algae-supplemented aquafeed(for comparison purposes,10%supplementation with fillet of fish standardly fed was also considered).Thereafter,mice were challenged by the genotoxicant methyl methanesulfonate(MMS),and the genetic damage was evaluated through the micronuclei ***,a wider evaluation was carried out encompassing the assessment of energy metabolism,haematological and histological parameters,as well as growth *** unequivocally protected against MMS-induced *** activity profile of hepatic lactate and isocitrate dehydrogenases promoted by the supplemented diets reflected an improved energy *** properties were not transferred via fish fed with the algae-supplemented aquafeed,though the transference of phytocomponents with beneficial properties(*** balance improvement)should not be ***,these findings highlighted the genoprotection afforded by marine macroalgae,likely promoted by desmutagenic factors,reinforcing their definition as functional *** possibility of using fish as an indirect source of algae-borne phytocomponents proved to be plausible and worthy of further investigations.

关键词： Antigenotoxicity Desmutagens Fish consumption Functional food Marine macroalgae consumption Metabolic benefits

Adsorbents Derived from Xylan Hemicellulose with Removal Properties of Pollutant Metals

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Chinese Journal of Polymer Science 2023年第6期41卷 874-886,I0007页

作者： Elizabeth Elgueta Yerko Becerra ana Martínez Miguel pereira Isabel Carrillo-Varela Felipe Sanhueza Dariela Nuez BernabéL.Rivas Centro de Investigación de Polímeros Avanzados CIPAAvenida Collao 1202Edificio de LaboratoriosConcepcionChile Departamento de Química Ambiental Facultad de CienciasUniversidad Católica de la Santísima ConcepciónCaila 160-cConcepcionChile Polymer Department Faculty of ChemistryUniversity of ConcepciónCasilla 160-CConcepcionChile Departamento de Ingeniería Química Facultad de IngenieríaUniversidad de ConcepciónConcepcionChile Department of Materials Engineering Faculty of EngineeringUniversidad de ConcepciónConcepcionChile

The adsorption capacity of hydrogels derived from modified xylan hemicellulose has been tested in order to develop new bio-based adsorbent materials useful for removing metal ions pollutants,such as Cd(Ⅱ),Cu(Ⅱ)and Pb(Ⅱ)from an aqueous *** was extracted from bleached kraft pulp of eucalyptus and subsequently modified with different proportions of functional sulfonic acid groups(HA3-HA7)and sulfonate groups(HS30-HS70)to generate *** results showed that all the synthesized hydrogels were capable of adsorbing metal ions,being the hydrogels with 30%and 50%xylan the ones that presented the highest adsorption *** capacity studies at different initial concentrations revealed that at an initial concentration of 300 mg·L-1,the HA3 hydrogel presented an adsorption capacity of 193mg Pb(Ⅱ),182 mg Cd(Ⅱ),and 66 mg Cu(Ⅱ)per g *** HA5 hydrogel presented a capacity of 185 mg Pb(Ⅱ),113 mg Cd(Ⅱ),and 48 mg Cu(Ⅱ)per g *** HS30 hydrogel exhibited an adsorption of 205 mg Pb(Ⅱ),174 mg Cd(Ⅱ),and 71 mg Cu(Ⅱ)per g hydrogel,and HS50 hydrogel exhibited an adsorption capacity of 273 mg Pb(Ⅱ),143 mg Cd(Ⅱ),and 45 mg Cu(Ⅱ)per g *** results show that modified Xylan hemicellulose is a promising adsorbent for removal Cd(Ⅱ),Cu(Ⅱ),and Pb(Ⅱ)ions from aqueous solutions.

关键词： Pb(Ⅱ) solution capacity

Neotropical mustelids: fecal metabolome diversity and its potential for taxonomic discrimination

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Integrative Zoology 2023年第3期18卷 518-529页

作者： Lana Resende de ALMEIDA Marina Amaral ALVES ana Maria Obino MASTELLA Rafael GARRETT Maria João Ramos pereira Bird and Mammal Evolution Systematics and Ecology LabPrograma de Pós-Graduação em Biologia AnimalUniversidade Federal do Rio Grande do SulPorto AlegreRio Grande do SulBrazil Programa de Pós-Graduação em Biologia Animal Universidade Federal do Rio Grande do SulPorto AlegreRio Grande do SulBrazil Chemistry Institute Metabolomics Laboratory(LabMeta–LADETEC/IQ–UFRJ)Avenida Horácio MacedoFederal University of Rio de JaneiroRio de JaneiroRJBrazil Walter Mors Institute of Research on Natural Products Universidade Federal do Rio de JaneiroRio de JaneiroRJBrazil

Chemical proﬁles of non-invasive biological material,such as feces,have great potential to study elusive animals or those with low population ***,we use a metabolomic approach to evaluate Neotropical mustelids as a biological model to describe the diversity of the metabolites present in fecal samples,as well as to evaluate the potential of chemical proﬁles for taxonomic *** collected fecal samples from captive individuals of 5 species of mustelids occurring in Brazil and analyzed them by liquid chromatography coupled to high-resolution mass *** 200 compounds have been annotated;“bile acids,alcohols and derivatives”was the most expressive class in the metabolome of all the *** successfully discriminated 3 taxonomic groups:1—tayra(Eira barbara);2—otters(Lontra longicaudis and Pteronura brasiliensis;1);and 3—grisons(Galictis vittata and Galictis cuja).Several compounds seemed to be associated with food intake and the digestive process,while others were found for theﬁrst time in Neotropical *** concluded that mustelids show high metabolome diversity and that species-speciﬁc identiﬁcation through metabolomic proﬁles is possible,thus contributing to the development and implementation of additional non-invasive approaches in the study of mustelids.

关键词： chemical proﬁles ecology high-resolution mass spectrometry metabolomics Mustelidae

Noninvasive diagnosis of periportal fibrosis in schistosomiasis mansoni:A comprehensive review

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World Journal of Hepatology 2022年第4期14卷 696-707页

作者： Joelma Carvalho Santos Caroline Louise Diniz pereira ana Lúcia Coutinho Domingues Edmundo Pessoa Lopes Postgraduate Program in Tropical Medicine Center of Health SciencesUniversidade Federal de PernambucoRecife 50670-901PernambucoBrazil Gastroenterology Division Department of Internal Medicine of Center of Health SciencesHospital das Clínicas-Universidade Federal de PernambucoRecife 50670-901PernambucoBrazil

Schistosomiasis mansoni is a neglected disease and key public health problem,mainly due to its high prevalence,the scarcity of public policies,and the severity of some clinical *** fibrosis(PPF)is the commonest complication of chronic schistosomiasis mansoni and its diagnosis requires different *** though wedge biopsy of the liver is considered the gold standard,it is not justified in non-surgical patients,and percutaneous liver biopsy may be informative but does not have sufficient *** PPF tests mostly include biological(serum biomarkers or combined scores)or physical assessments(imaging assessment of fibrosis pattern or tissue stiffness).Moreover,imaging techniques,such as ultrasound,computed tomography,magnetic resonance imaging,and elastography are applied not only to support the diagnosis of schistosomiasis,but also to assess and detect signs of portal hypertension and organ damage due to chronic schistosomiasis.A combination between a comprehensive history and physical examination with biomarkers for liver fibrosis and imaging methods seems to offer the best approach for evaluating these *** addition,understanding their strengths and limitations will allow a more accurate interpretation in the clinical context and can lead to greater accuracy in estimating the degree of fibrosis in patients with Schistosomiasis mansoni(***)*** review will discuss the different noninvasive methods that are currently available for the evaluation of PPF in *** infection,and their application,advantages,and limitations in clinical practice.

关键词： Schistosoma mansoni Parasitic liver diseases Liver fibrosis Biomarkers Elasticity imaging techniques Ultrasonography

Hepatic“pregnancy”:hepatocellular carcinoma with extensive extrahepatic growth

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Hepatobiliary Surgery and Nutrition 2023年第4期12卷 641-642页

作者： ana Rita Ferreira Bárbara Castro Jose Daniel Martins João Varanda Alexandre Costa Bela pereira Manuel Oliveira General Surgery Centro Hospitalar Vila Nova de Gaia/EspinhoVila Nova de GaiaPortugal

A female in her 50s,no previous personal history,presented to the Emergency Department with a 7 months history of progressively worsening abdominal diffuse pain associated with increasing abdominal *** physical examin... 详细信息

关键词： pregnancy Hepatic Figure

Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers: neurodegenerative diseases, tissue engineering and regenerative medicine

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Military Medical Research 2023年第5期10卷 699-725页

作者： Daniela Lopes Joana Lopes Miguel pereira-Silva Diana Peixoto Navid Rabiee Francisco Veiga Omid Moradi Zhan-Hu Guo Xiang-Dong Wang Joao Conde Pooyan Makvandi ana Claudia Paiva-Santos Department of Pharmaceutical Technology Faculty of Pharmacy of the University of CoimbraUniversity of Coimbra3000-548 CoimbraPortugal REQUIMTE/LAQV Group of Pharmaceutical TechnologyFaculty of Pharmacy of the University of CoimbraUniversity of Coimbra3000-548 CoimbraPortugal School of Engineering Macquarie UniversitySydneyNsW 2109Australia Centre for Molecular Medicine and Innovative Therapeutics Murdoch UniversityPerthWA 6150Australia Department of Chemistry Shahr-e-Qods BranchIslamic Azad UniversityTehran 374-37515Iran lntegrated Composites Laboratory(iCL) Department of Mechanical and Construction EngineeringNorthumbria UniversityNewcastle Upon Tyne NE18STUK Department of Pulmonary and Critical Care Medicine Zhongshan HospitalFudan University Shanghai Medical CollegeShanghai 200032China Faculdade de Ciencias Medicas NOVA Medical SchoolUniversidade Nova de Lisboa1169-056 LisbonPortugal Centre for Toxicogenomics and Human Health GeneticsOncology and Human ToxicologyFaculdade de Ciencias MedicasNOVA Medical SchoolUniversidade Nova de Lisboa1169-056 LisbonPortugal school of Engineering Institute for Bioengineeringthe University of EdinburghEdinburgh EH93JLUK.

A bio-inspired strategy has recently been developed for camouflaging nanocarriers with biomembranes,such as natural cell membranes or subcellular structure-derived *** strategy endows cloaked nanomaterials with improved interfacial properties,superior cell targeting,immune evasion potential,and prolonged duration of systemic ***,we summarize recent advances in the production and application of exosomal membrane-coated *** structure,properties,and manner in which exosomes communicate with cells are first *** is followed by a discussion of the types of exosomes and their fabrication *** then discuss the applications of biomimetic exosomes and membrane-cloaked nanocarriers in tissue engineering,regenerative medicine,imaging,and the treatment of neurodegenerative ***,we appraise the current challenges associated with the clinical translation of biomimetic exosomal membrane-surface-engineered nanovehicles and evaluate the future of this technology.

关键词： Biomimetic Cell membrane coating Exosome Exosomal-membrane-coated nanoparticle Extracellular vesicle(EV)

An illustrated checklist of macrofaunal molluscs from soft-sediments of the Abrolhos Parcel(northeastern,Brazil)with 15 new records

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Journal of Oceanology and Limnology 2021年第2期39卷 671-682页

作者： Flávia Maria pereira da COSTA ana Maria Setubal PIRES-VANIN Departamento de Oceanografi a Biológica Instituto Oceanográfi coUniversidade de São PauloSão Paulo 05508-120Brazil

Comprehensive understanding of marine biodiversity is essential for conservation,especially for vulnerable *** this paper,we implemented and illustrated a checklist of molluscs from the Abrolhos Parcel,Brazil,the most important coralline area in South Atlantic *** list features 100 species belonging to 4 classes and 85 genera,of which 15 are new records for Bahia State,northeast *** results highlight the potential for new records in the *** species came from 54 unconsolidated sediment samples collected from the bottom of the reef with a 0.042-m^(2) van Veen *** the listed species,Curveulima sp.,Notarchus *** Guyanella clenchi are new records for the South Atlantic,while Caecum metamorphosicum,Eratoidea janeiroensis,Volvarina serrei,Solemya notialis,Solariorbis shimeri,and Amphithalamus glabrus are endemic to Brazilian waters.A comparison of our results with those obtained in other reef environments indicates that the Abrolhos Parcel has a rich malacofauna and suggests that many more species can still be found with more samplings.

关键词： Bivalvia Gastropoda micromolluscs Scaphopoda Solenogastres southwest Atlantic