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Advances in fabricating spherical alginate hydrogels with controlled particle designs by ionotropic gelation as encapsulation systems

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Particuology 2016年第1期14卷 44-60页

作者： Jun-Yee Leong Weng-Hoong Lam Kiang-Wei Ho Wan-Ping Voo Micky Fu-Xiang Lee Hui-peng lim Swee-Lu lim Beng-Ti Tey Denis Poncelet alan Lagoon Selatan Bandar Sunway Selangor 46150 Malaysia Advanced Engineering Platform Monash University Malaysia Jalan Lagoon Selatan Bandar Sunway Selangor 46150 Malaysia Oniris UMR CNRS 6144 GEPEA rue de la Geraudiere BP82225 Nantes 44322 France

Alginate is a biopolymer that has exceptional gelling properties, which allow easy gel formation under safe and mild conditions. Consequently, it is often used to encapsulate a variety of cargos, such as cells, enzymes, and lipids, and is typically employed as a model to study hydrogel-based encapsulation sys- tems. Since the first use of alginate in the encapsulation field in the 1970s, many methods have been developed to produce alginate hydrogel particles of different sizes, structures, and morphologies. This review provides an overview of the current progress in the fabrication of alginate hydrogels with vari- ous particle designs, including a discussion of dispersion techniques to pre-template alginate particles, gelation mechanisms, considerations in selecting suitable fabrication methods, and future directions.

关键词： Alginate lonotropic gelation Immobilization Encapsulation Hydrogel

An Ensemble Application of Conflict-Resolving ART-Based Neural Networks to Fault Detection and Diagnosis

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Journal of Measurement Science and Instrumentation 2011年第4期2卷 371-377页

作者： Shing-chiang TAN Chee-peng lim Faculty of Information Science ＆ Technology Multimedia University Bukit Beruang Melaka 75450 Malaysia School of Computer Science of University of Science Malaysia Gelugor Penang 11700 Malaysia

Accurate fault detection and diagnosis is important for secure and profitable operation of modern power *** this paper,an ensemble of conflict-resolving Fuzzy ARTMAP classifiers,known as Probabilistic Multiple Fuzzy ARTMAP with Dynamic Decay Adjustment(PMFAMDDA),for accurate discrimination between normal and faulty operating conditions of a Circulating Water(CW)system in a power generation plant is *** decisions of PMFAMDDA are reached through a probabilistic plurality voting strategy that is in agreement with the Bayesian *** results of the proposed PMFAMDDA model are compared with those from an ensemble of Probabilistic Multiple Fuzzy ARTMAP(PMFAM)*** outcomes reveal that PMFAMDDA,in general,outperforms PMFAM in discriminating operating conditions of the CW system.

关键词： fault detection and diagnosis fuzzy ARTMAP dynamic decay adjustment algorithm pluralityvoting circulating water system

New mesogenic Schiff base esters comprising benzothiazole moiety:Synthesis and mesomorphic properties

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Chinese Chemical Letters 2009年第9期20卷 1081-1084页

作者： Sie Tiong Ha Teck Ming Koh Guan Yeow Yeap Hong Cheu Lin Jun Kit Beh Yip Foo Win peng lim Boey Faculty of Engineering & Science Universiti Tunku Abdul RahmanJln Genting KlangSetapak 53300 Kuala LumpurMalaysia Liquid Crystal Research Laboratory School of Chemical SciencesUniversiti Sains Malaysia 11800 MindenPenangMalaysia Department of Materials Science & Engineering National Chiao Tung University1001 Ta-Hsueh RoadHsinchu 300Taiwan Faculty of Science Engineering & TechnologyUniversiti Tunku Abdul RahmanJln UniversitiBandar Barat 31900 KamparPerakMalaysia

A homologous series of Schiff base esters, 6-methoxy-2-（2-hydroxy-4-alkanoyloxybenzylidenamino）benzothiazoles, compris- ing a benzothiazole moiety as the core was synthesized. All the members of this series exhibited an enantiotropic nematic phase. The azomethine linkage along with the lateral hydroxyl and terminal methoxyl groups were found to exert an effect on the mesomorphic properties. 2009 Sie Tiong Ha. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Schiff bases Benzothiazoles Mesomorphic Nematic Structure-liquid crystal property relationship

A Cascade Genetic Algorithm and Particle Swarm Approach for Solving Unit Commitment and Economic Dispatch Problems

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A Cascade Genetic Algorithm and Particle Swarm Approach for ...

第二届亚洲机械电子学学术会议

作者： Siew Chin Neoh Norhashimah Morad Chee peng lim Zalina Abdul Aziz School of Electrical and Electronic Engineering Universiti Sains Malaysia Engineering Campus Nibong Tebal 14300 Pulau Pinang Malaysia

Unit commitment and economic dispatch are two important decisions in thermal power generation scheduling. The tasks involve determination and allocation of power generation to thermal units that minimize the total power generation cost and satisfy the production *** paper presents a cascade Genetic Algorithm and Particle Swarm Optimization(GA-PSO)approach for solving thermal power generation scheduling based on a layered matrix encoding *** proposed hybrid method is compared to layered matrix encoding GA using the thermal power generation problem given in Williams[1]to demonstrate its effectiveness in generating an optimal,cost-effective power generation *** results showed that cascade GA-PSO outperformed the layered matrix encoding GA in minimizing the total power production cost for unit commitment and power dispatch problems.

关键词： Particle Swarm Optimization Genetic Algorithms Thermal Power Scheduling

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DMFC燃料电池便携式应用前景

电子产品世界 2009年第1期16卷 70-73页

作者： peng lim MTI公司

由于电池技术跟不上电子产品的发展速度,便携式电源亟待创新。直接甲醇燃料电池(DMFC)技术可确保更长的运行时间,并可在任何远离电网电源的地方即时充电,因而可提供真正的移动性。

关键词： DMFC 燃料电池便携产品甲醇

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亚太地区的两种重要禽病

国外畜牧科技 1994年第3期21卷 44-45页

作者： lim peng Guan 祁保民

1 超强毒型传染性法氏囊病通过种鸡和21日龄雏鸡两次灭活苗免疫,曾在70年代末和80年代初称之为临床型的传染性法氏囊病现在已转变为亚临床型。然而,1987年首次在比利时,随后英国报道了发生临床型的超强毒型传染性法氏囊病(vvIBD),并认... 详细信息

1 超强毒型传染性法氏囊病通过种鸡和21日龄雏鸡两次灭活苗免疫,曾在70年代末和80年代初称之为临床型的传染性法氏囊病现在已转变为亚临床型。然而,1987年首次在比利时,随后英国报道了发生临床型的超强毒型传染性法氏囊病(vvIBD),并认为由vvIBD病毒引起。其临床症状与标准毒株引起的相似,但死亡率高达30％～70％,且雏鸡发病较早。最后该病迅速传播整个欧洲。

关键词：禽病头肿综合症亚太地区 IBD

一位药物性牙龈增生患者的诊断、治疗和长期疗效

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中国口腔医学继续教育杂志 2009年第3期12卷 27-34页

作者： Wah Ching Tan Lure peng lim Niklaus Peter Lang 乔敏（译）徐莉审不详北京大学口腔医学院牙周科北京海淀区中关村南大街22号100081

本文报告了1例服用环孢素和硝苯地平相关牙龈增生（肥大）患者的诊断、治疗和长期疗效。该患者在未更换全身用药情况下对牙龈增生进行了成功治疗。治疗的主要目的是降低牙龈增生的程度，进而恢复牙齿的健康、功能和美观。治疗过程是先... 详细信息

本文报告了1例服用环孢素和硝苯地平相关牙龈增生（肥大）患者的诊断、治疗和长期疗效。该患者在未更换全身用药情况下对牙龈增生进行了成功治疗。治疗的主要目的是降低牙龈增生的程度，进而恢复牙齿的健康、功能和美观。治疗过程是先行牙周基础治疗，后行牙周手术治疗，术后观察2年．牙龈增生未见复发。

关键词：环孢菌素牙龈肥大维护治疗硝苯地平

Transcription factor EHF interacting with coactivator AJUBA aggravates malignancy and acts as a therapeutic target for gastroesophageal adenocarcinoma

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2119-2136页

作者： Li peng Yanyi Jiang Hengxing Chen Yongqiang Wang Qiusheng Lan Shuiqin Chen Zhanwang Huang Jingyuan Zhang Duanqing Tian Yuntan Qiu Diankui Cai Jiangyun peng Daning Lu Xiaoqing Yuan Xianzhu Yang Dong Yin Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Guangdong-Hong Kong Joint Laboratory for RNA MedicineSun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Medical Research Center Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Hefei Institutes of Physical Science Chinese Academy of SciencesHefei 230031China Department of Gastrointestinal Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Department of Hepatobiliary Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China School of Biomedical Sciences and Engineering South China University of TechnologyGuangzhou International CampusGuangzhou 511442China

Transcriptional dysregulation of genes is a hallmark of tumors and can serve as targets for cancer drug ***,it is extremely challenging to develop small-molecule inhibitors to target abnormally expressed transcription factors(TFs)except for the nuclear receptor family of *** is known about the interaction between TFs and transcription cofactors in gastroesophageal adenocarcinoma(GEA)or the therapeutic effects of targeting TF and transcription cofactor *** this study,we found that ETS homologous factor(EHF)expression is promoted by a core transcriptional regulatory circuitry(CRC),specifically ELF3-KLF5-GATA6,and interference with its expression suppressed the malignant biological behavior of GEA ***,we identified Ajuba lim protein(AJUBA)as a new coactivator of EHF that cooperatively orchestrates transcriptional network activity in ***,we identified KRAS signaling as a common pathway downstream of EHF and ***,dual targeting of EHF and AJUBA by lipid nanoparticles cooperatively attenuated the malignant biological behaviors of GEA in vitro and in *** conclusion,EHF is upregulated by the CRC and promotes GEA malignancy by interacting with AJUBA through the KRAS *** of both EHF and its coactivator AJUBA through lipid nanoparticles is a novel potential therapeutic strategy.

关键词： EHF AJUBA KRAS pathway Enhancer Core transcriptional regulatory circuitry Gastroesophageal adenocarcinoma Gastric adenocarcinoma Esophageal adenocarcinoma Transcription factor Coactivator Lipid nanoparticles

Steady formation analysis onmulti-robot systems

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Journal of Control and Decision 2017年第1期4卷 12-31页

作者： Yutong Liu Hongjun Yu Cheng-Chew lim peng Shi School of Electrical and Electronic Engineering University of AdelaideAdelaideAustralia

In this paper,a controller is designed for a group of cooperative robots to achieve the stable *** network among the robots is assumed unavailable and each robot can only measure the displacements relative to their *** controller will enable the robots to move to a predefined formation or a special formation under a suitable protocol which we will *** will discuss the effect of different sizes of the multi-vehicle system and conduct simulations to verify the effectiveness of the proposed controller and the formation protocols.

关键词： Formation control limited sensing range controller design size of multi-vehicle system