检索结果-南通市图书馆

The Effects of Lactobacillus rhamnosus GG on Mechanical Properties of Long Bones and Body Composition in Immunodeficient Mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2016年第3期7卷 173-179页

作者： Violetta Naughton Dorian Dixon Lisa Rainey Cormac McGarrigle patrick j. Naughton Biomedical Sciences Research Institute School of Biomedical Sciences Ulster University Coleraine UK Engineering Research Institute School of Engineering Ulster University Jordanstown UK Centre for Cancer Research and Cell Biology School of Medicine Dentistry and Biomedical Sciences Queen’s University Belfast UK

This study aimed to assess whether a daily supplementation with Lactobacillus rhamnosus GG (LGG) can alter the body composition as well as bone turnover and the mechanical properties of the bones in systemic immunodeficiency. For this, we use an in vivo model of severe combined immunodeficient (scid) mice supplemented daily with LGG over 8 weeks period. After 8 weeks of the treatment, the animals were assessed by DEXA and then the blood was collected from the hepatic portal vein for bone turnover biomarkers;post-mortem, the caecum was removed for isolation and enumeration of the gut bacteria, while femurs/tibiae were excised for the assessment of their mechanical properties. LGG treatment affected the composition of the gut microbiota at the order level, and it decreased (P = 0.002) total adipose tissue content. Moreover, LGG treatment decreased the stiffness (N/mm) of both femurs (P = 0.008) and tibiae (P = 0.011). To conclude, this study shows that dietary supplementation with LGG in immunodeficient animals can alter mechanical properties of the long bones and concomitantly it can modify host’s total adiposity level.

关键词： Lactobacilli Bone Body Composition

Saturation-excess overland flow in the European loess belt:An underestimated process?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Soil and Water Conservation Research 2023年第4期11卷 688-699页

作者： Valentin Landemaine Olivier Cerdan Thomas Grangeon Rosalie Vandromme Benoit Laignel Olivier Evrard Sébastien Salvador-Blanes j.patrick Laceby BRGM F-45060OrléansFrance University of Rouen M2CRouenFrance Laboratoire des Sciences du Climat et de l'Environnement(LSCE/IPSL) UnitéMixte de Recherche 8212(CEA/CNRS/UVSQ)UniversitéParis-SaclayGif-sur-YvetteFrance University of Tours UR 6293-GéoHydrosystèmes Continentaux(GEHCO)France Alberta Environment and Protected Areas CalgaryCanada

A maj.r challenge in runoff and soil erosion modelling is the adequate representation of the most relevant processes in models while avoiding over *** the European loess belt,pro-gressive soil crusting during rainfall events,resulting in infiltration-excess runoff,is usually considered the dominant process generating runoff on catchments covered with silty ***-excess may also occur and affect their runoff and erosion ***,saturation-excess runoff occurrence and quantification have rarely been performed and is usually not taken into account when modelling runoff and erosion in these ***,a continuous simulation of the Austreberthe catchment(214 km^(2)),located in the European loess belt(Normandy,France),was conducted with the new Water and Sediment(WaterSed)model over 12 years,corresponding to more than 780 individual rainfall events,at a 25 m spatial *** inter-annual variability of runoff and erosion was closely linked to the number of intense events per year and their distribution through the *** model was properly calibrated over a representative set of 35 rainfall events,considering either infiltration-excess and/or saturation-excess *** was also able to reproduce the measured runoff volume for most of the monitoring ***,the three years with most rainfall were adequately modelled only including saturation-excess *** analysis performed at the seasonal scale revealed that saturation was modelled in the catchment during almost all of the modelling period,suggesting the importance of this often overlooked process in current modelling attempts.

关键词： European loess belt Soil erosion Saturation-excess runoff WaterSed model

Understanding temporal stability:a long-term analysis of USDA ARS watersheds

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International j.urnal of Digital Earth 2021年第10期14卷 1243-1254页

作者： Evan j.Coopersmith Michael H.Cosh patrick j.Starks David D.Bosch Chandra Holifield Collins Mark Seyfried Stan Livingston j.hn Prueger Soil Insight LLCWashington D.C.USA USDA-Agricultural Research Service Beltsville Agricultural Research CenterHydrology and Remote Sensing LaboratoryBeltsvilleUSA USDA-Agricultural Research Service-Grazinglands Research Laboratory El RenoUSA USDA-Agricultural Research Service-Southeast Watershed Research Laboratory TiftonUSA USDA-Agricultural Research Service-Southwest Watershed Research Center TucsonUSA USDA-Agricultural Research Service-Northwest Watershed Research Laboratory BoiseUSA USDAAgricultural Research Service-National Soil Erosion Research Laboratory West LafayetteUSA USDA-Agricultural Research Service-National Laboratory for Agriculture and Environment AmesUSA

The *** of Agriculture’s Agricultural Research Service(USDAARS)maintains seven in situ soil moisture networks throughout the continental United States,some since *** networks are crucial for understanding the spatial and temporal extent of droughts in their historical context,parameterization of hydrologic models,and local agricultural decision ***,the estimates from these networks are dependent upon their ability to provide reliable soil moisture information at a large *** is also not known how many network stations are sufficient to monitor watershed scale ***,the obj.ctives of this research were to:(1)determine how temporally stable these networks are,including the relationships between various sensors on a year-to-year and seasonal basis,and(2)attempt to determine how many sensors are required,within a network,to approximate the full network *** data from seven in situ,it is concluded that approximately 12 soil moisture sensors are sufficient in most environments,presuming their locations are distributed to capture the hydrologic heterogeneity of the *** is possible to install a temporary network containing a suitable number of sensors for an appropriate length of time,glean stable relationships between locations,and retain these insights moving forward with fewer sensor resources.

关键词： Soil moisture temporal stability in situ networks

Hemispheric Specialization of the Primate Inferior Parietal Lobule

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neuroscience Bulletin 2022年第3期38卷 334-336页

作者： Sam Vickery Simon B Eickhoff patrick Friedrich Institute of Neuroscience and Medicine Brain&Behaviour(INM-7)Research Centre Jülich52428JülichGermany Institute of Systems Neuroscience Medical FacultyHeinrich-Heine University Düsseldorf40225DüsseldorfGermany

Hemispheric asymmetries can be seen as one of the evolutionary adaptations that allowed the human brain to muster more complex cognitive processes than other *** this vein,the study published by Cheng et al.[1]presents a pivotal investigation of both the regional and connectional asymmetries within the inferior parietal lobule(IPL)in human,chimpanzee,and *** investigating 4 sub-divisions of the IPL across the three species,Cheng and colleagues showed that the macroanatomical and connectional architecture of the IPL became more asymmetric throughout the primate *** macaques show little to no structural asymmetries,chimpanzees display a more asymmetric architecture but with both leftward and rightward asymmetries in various *** contrast,the human IPL displayed the highest number of asymmetries among the three species with a clear tendency towards more *** evolutionary trend towards a more lateralized organization of the IPL may have accompanied an improved command of tool-use,stronger forelimb asymmetries,and the increasing complexity of communicative behavior.

关键词： asymmetric erior allowed

Stress rise precursor to earthquakes in the Tibetan Plateau

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural Science 2013年第8期5卷 46-55页

作者： Zhenhan Wu Qunce Chen patrick j. Barosh Hua Peng Daogong Hu Chinese Academy of Geological Sciences Beijing China Institute of Geomechanics Chinese Academy of Geological Sciences Beijing China P.j. Barosh and Associates Bristol USA

Earthquake prediction thus far has proven to be a very difficult task, but changes in situ stress appear to offer a viable approach for forecasting large earthquakes in Tibet and perhaps other continental regions. High stress anomalies formed along active faults before large earthquakes and disappeared soon after the earthquakes occurred in the Tibetan Plateau. Principle stress increased up to ~2 -?5 times higher than background stress to form high stress anomalies along causative faults before the Ms 8.1 West Kunlun Pass earthquake in November 2001, Ms 8.0 Wenchuan earthquake in May 2008, Ms 6.6 Nimu earthquake in October 2009, Ms 7.1 Yushu earthquake in April 2010 and the Ms 7.0 Lushan earthquake in April 2013. Stress near the epicenters rapidly increased 0.10 - 0.12 MPa over 45 days, ~8 months before the Ms 6.6 Nimu earthquake occurred. The high principle stress anomalies decreased quickly to the normal stress state in ~8 -?12 months after the Ms 8.1 West Kunlun Pass and the Ms 8.0 Wenchuan earthquakes. These high stress anomalies and their demise appear directly related to the immediate stress rise along a fault prior to the earthquakes and the release during the event. Thus, the stress rise appears to be a viable precursor in prediction of large continental earthquakes as in the Tibetan Plateau.

关键词： Earthquake Prediction High Stress Anomalies In-Situ Stress Measurement Large Earthquakes Seismic Fault Tibetan Plateau

Gas flow in rotary kilns

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2010年第6期8卷 613-616页

作者： patrick R.Davies Michael j.S.Norton D.Ian Wilson j.hn F.Davidson David M.Scott Department of Chemical Engineering and Biotechnology University of CambridgePembroke StreetCambridgeCB2 3RAUK

This paper describes an experimental investigation on the flow characteristics within a rotating cylinder containing a rolling bed of sand. The axis of the cylinder was horizontal and there was no axial bulk flow of particles. The velocity field of the gas flowing through the cylinder was measured by hot-wire anemometry. The measurements indicate that the velocity field is asymmetric with respect to a diameter perpendicular to the granular bed. CFD calculations confirm this finding. The gas velocity profiles are crucial in determining heat transfer from gas to solid.

关键词： Rotating cylinderVelocity profile

Geomorphic Habitat Type, Drift Cell, Forage Fish and j.venile Salmon： Are They Linked？

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

j.urnal of Environmental Science and Engineering(A) 2012年第5期1卷 688-703页

作者： j. Anne Shaffer patrick Crain Todd Kassler Dan Penttila Dwight Barry Coastal Watershed Institute Port Angeles Washington 98362 USA Olympic National Park Port Angeles Washington 98362 USA Washington Department ofFish and Wildlife Molecular Genetics Laboratory Olympia Washington 98501 USA Salish Sea Biological Incorporated Anacortes Washington 98221 USA Huxley College of the Environment-Peninsulas Western Washington University Port Angeles Washington 98362 USA

The role of geomorphic habitat type, drift cell scale, and geographic scale in defining fish use of nearshore habitats is poorly known, particularly for Pacific salmon and their prey. In this study, key areas of nearshore habitat in central and western Strait of j.an de Fuca were categorized by geomorphic habitat type and assessed for fish use within a degraded （Elwha） and intact comparative drift cells over a one year period. j.venile Chinook and coho salmon were also sampled for genetic analysis to define regional dispersal patterns. Key findings are：（1） Ecological function of the area＇s nearshore is complex, with very strong seasonal variation in fish use both within and across GMHT （geomorphic habitat type）; （2） GMHT link to nearshore function for fish use differs depending on the fish species and time of year. Surf smelt and sand lance were the most abundant. And they were seasonally used embayed, spit, and bluff shorelines more than lower rivers. j.venile Chinook, coho, and chum salmon occurred in much lower density than forage fish species, and used lower rivers more than other GMHTs; （3） When GMHTs were combined and analyzed at the drift cell scale, the degraded drift cell had different ecological patterns than the intact drift cell; （4） Cross regional j.venile fish use of nearshore is an important component of habitat use： j.venile Chinook and coho from as far away as the Columbia River Oregon and Klamath River California utilize central Strait of j.an de Fuca shorelines. Forage fish species may do so as well. Drift cell and cross regional scales are therefore most important for accurately defining nearshore ecological function, management, and restoration actions.

关键词： Nearshore geomorphic habitat type fish use Elwha Chinook.

Cost-effectiveness analysis comparing robotic sacrocolpopexy to a vaginal mesh hysteropexy for treatment of uterovaginal prolapse

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open j.urnal of Obstetrics and Gynecology 2013年第8期3卷 613-620页

作者： patrick j. Culligan Charbel Salamon Christa Lewis Troy D. Abell Atlantic Health System Division of Urogynecology and Reconstructive Pelvic Surgery Morristown USA

Obj.ctive: To compare costs and QoL associated with 2 minimally invasive operations to treat uterovaginal prolapse. Study Design: A decision analytic cost-effectiveness model comparing vaginal mesh hysteropexy to robotic-assisted sacrocolpopexy. Costs were derived from a hospital perspective. QoL estimates focused on: recurrent prolapse;erosion;infection;transfusion;cystotomy;chronic pain;lower urinary tract symptoms;and mortality. Actual procedural costs at our institution were calculated. Costs and quality adj.sted life years were examined over 1 year. Results: The costs ($21,853) and QALYs (0.9645) for robotic sacrocolpopexy produced a CE Ratio of $22,657 per QALY. The costs ($14,890) and QALYs (0.9309) for vaginal mesh produced a CE Ratio of $15,995 per QALY. The incremental cost per QALYs for robotic surgery was $207,232. Sensitivity analysis on all utilities, cost estimates, and complication estimates didn’t cross any thresholds. Conclusion: Vaginal mesh was more cost-effective than robotic sacrocolpopexy even when the cost of the robot was not factored.

关键词： Cost-Effectiveness Robotic-Sacrocolpopexy Uterovaginal Prolapse Vaginal-Mesh

A concise introduction to logic 8th ed.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A concise introduction to logic