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Downwash airflow distribution pattern of hexa-copter unmanned aerial vehicles

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International Journal of Agricultural and Biological Engineering 2024年第4期17卷 24-34页

作者： Dengeru Yallappa Ramasamy Kavitha Allimuthu Surendrakumar Kannan Balaji Balakrishnan Suthakar Ayyasamy paramasivam Mohan Kumar Yathendranaik Ravi Narayananaik Ashoka Kumar Kavan Department of Farm Machinery and Power Engineering Agricultural Engineering College and Research InstituteTamil Nadu Agricultural UniversityCoimbatore

In recent times,the use of vertical take-off and landing(VTOL)multi-rotor Unmanned Aerial Vehicle(UAVs)for spraying chemical pesticides against weeds and pests has recently become *** current aerial spray application research is primarily focused on examining the influence of UAV spraying parameters such as flight height,travel speed,rotor configuration,droplet size,payload and wind *** downwash airflow velocity generated by the UAV rotor propeller has a significant impact on the droplet deposition process.A test rig was developed to measure the downwash airflow pattern generated by the rotor propeller of a *** this investigation,a six-rotor electric autonomous UAV sprayer was used to investigate the parameters and distribution laws of downwash airflow *** downwash airflow velocity was measured using portable anemometers mounted on the test rig at radial positions viz.,0 m,0.5 m,1 m,1.5 m and 2 m,perpendicular to(X)and parallel to the UAV’s flight direction(Y).The experiment was conducted at three levels of hover height,viz.,1 m,2 m and 3 m(Z)and three levels of payload,viz.,0 kg,5 kg,and 10 *** special downwash airflow distribution pattern was analysed using the Python programming language(Version 3.7).Results show that the downwash airflow velocity generated by the radial position of the UAV rotor is evenly distributed on the rotating loop and the standard deviation of the downwash airflow velocity is less than 0.5 m/*** maximum downwash airflow velocity of 13.8 m/s was observed below the rotor at 10 kg payload capacity,1 m hover height(Z),and 0.5 m in the *** minimum downwash wind field of 0.3 m/s was observed at 0 kg pay load capacity,1 m height,and 2 m in the *** downwash airflow velocity along each position in the radial direction of the rotor increases initially and then *** downwash airflow distribution results helps in mounting of spray nozzle configuration to drone sprayer which helps to

关键词： downwash air payload rotor propeller flight height distribution analysis flight direction

Ceric ammonium nitrate supported HY-zeolite:An efficient catalyst for the synthesis of 1,8-dioxo-octahydroxanthenes

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Chinese Chemical Letters 2014年第2期25卷 321-323页

作者： paramasivam sivaguru Appaswami Lalitha Department of Chemistry Periyar University

Ceric ammonium nitrate （CAN） supported HY-zeolite has been used as an efficient catalyst for the one- pot synthesis of 1,8-dioxo-octahydroxanthenes from the readily available 1,3-diketone and aromatic aldehydes under solvent-free conditions. The present methodology is cost-effective in addition to other advantages like high yields of products in shorter reaction time and simple workup procedure without the use of any injurious solvents.

关键词： Ceric ammonium nitrate supported HY-zeolite 1,8-Dioxo-octahydroxanthenes One-pot synthesis Solvent-free conditions

Novel insights into m6A modification in circular RNA and implications for immunity

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Cellular & Molecular Immunology 2020年第6期17卷 668-669页

作者： Arumugam paramasivam Jayaseelan Vijayashree Priyadharsini Saveetha UniversityChennaiIndia

Chemical modifications play an important role in modifying and regulating the functions of coding and noncoding *** RNAs mainly include microRNAs(miRNAs),long noncoding RNAs(lncRNAs),and circular RNAs(circRNAs).A common feature of these noncoding RNAs is that they are all transcribed from the genome and can perform biological ***,the stable expression of noncoding RNAs in vivo makes them potential biomarkers for the diagnosis,prognosis,and clinical treatment of cancers and a variety of immunological diseases.

关键词： immunity diagnosis circular

Dissecting the theranostic potential of exosomes in autoimmune disorders

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Cellular & Molecular Immunology 2019年第12期16卷 935-936页

作者： Vijayashree Priyadharsini Jayaseelan paramasivam Arumugam Biomedical Research Unit and Laboratory Animal Centre-Dental Research Cell Saveetha Dental CollegeSaveetha Institute of Medical and Technical Sciences(SIMATS)Saveetha UniversityChennaiTamil Nadu 600077India

The biology of exosomes is a fascinating field of science that has attracted much attention from clinical researchers due to the plethora of associated *** biological cargoes serve as a hub of information about the health status of a cell or a group of *** reports on exosome-derived biomolecules in relation to diseases such as cancer,neurodegenerative diseases,and infectious diseases have spurred interest in exploring their role in the pathogenesis of other debilitating disease *** research into autoimmune disorders(ADs)in relation to exosome biology has identified novel therapeutic leads aiming to improve the life expectancy of individuals suffering from such disorders.1 One such important,notable contribution was recently shared by Guay et *** provided concreate evidence on the mechanism ofβcell apoptosis induced by the transfer of exosomal miRNAs derived from T cells,which eventually leads to type I diabetes *** crucial mediators of the process were T-lymphocyte-derived exosomes harboring miR-142-3p,miR-142-5p,and ***-miRs designed to block the interactions of miRNAs with their target genes insideβcells prevented the process of apoptosis,eventually rescuingβcells.2 Thus,targeting the mediators of crosstalk or blocking the function of exosomal miRNAs could serve as an interesting therapeutic strategy for type I diabetes mellitus(Fig.1).Consistent with the above report,this review highlights the contribution of exosomes to the development of autoimmune *** addition,this review also reveals the possible“theranostic”markers(therapeutic and diagnostic biomarkers)associated with ADs.

关键词： disorders autoimmune eventually

SVM Algorithm for Vibration Fault Diagnosis in Centrifugal Pump

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Intelligent Automation & Soft Computing 2023年第3期35卷 2997-3020页

作者： Nabanita Dutta Palanisamy Kaliannan paramasivam Shanmugam School of Electrical Engineering Vellore Institute of TechnologyVelloreTamilNaduIndia ESAB India Limited ChennaiIndia

Vibration failure in the pumping system is a signiﬁcant issue for indus-tries that rely on the pump as a critical device which requires regular *** save energy and money,a new automated system must be developed that can detect anomalies at an early *** paper presents a case study of a machine learning(ML)-based computational technique for automatic fault detection in a cascade pumping system based on variable frequency drive(VFD).Since the intensity of the vibrational effect depends on which axis has the most signiﬁcant effect,a three-axis accelerometer is used to measure it in the pumping *** emphasis is on determining the vibration effect on different *** experiment,various ML algorithms are investigated on collected vibratory data through Matlab software in x,y,z axes and performances of the algorithms are compared based on accuracy rate,prediction speed and training *** on the proposed research results,the multiclass support vector machine(MSVM)is found to be the best suitable algorithm compared to other *** has been demonstrated that ML algorithms can detect faults automatically rather than conventional *** is used for the proposed work because it is less complex and pro-duces better results with a limited data set.

关键词： Fault diagnosis machine learning pump vibration analysis variable frequency drive

Novel Power-Aware Optimization Methodology and Efficient Task Scheduling Algorithm

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Computer Systems Science & Engineering 2022年第4期41卷 209-224页

作者： K.Sathis Kumar K.paramasivam Department of Computer Science and Engineering Bannari Amman Institute of TechnologySathyamangalam638401TamilnaduIndia Department of Electrical and Electronics Engineering Kumaraguru College of TechnologyCoimbatore641049TamilnaduIndia

The performance of central processing units(CPUs)can be enhanced by integrating multiple cores into a single *** performance can be improved by allocating the tasks using intelligent *** Small tasks wait for long time or executes for long time,then CPU consumes more ***,the amount of power consumed by CPUs can be reduced without increasing the *** are used to connect cores,which are organized together to form a network called network on chips(NOCs).NOCs are mainly used in the design of ***,its performance can still be enhanced by reducing power *** main problem lies with task scheduling,which fully utilizes the ***,we propose a novel randomﬁt algorithm for NOCs based on power-aware *** this algorithm,tasks that are under the same application are mapped to the neighborhoods of the same application,whereas tasks belonging to different applications are mapped to the processor cores on the basis of a series of *** scheduling process is performed during the run *** results show that the proposed randomﬁt algorithm reduces the amount of power consumed and increases system performance based on effective scheduling.

关键词： Randomﬁt algorithm network on chips processor cores power-aware optimization

Thymoquinone inhibits the migration of mouse neuroblastoma(Neuro-2a) cells by down-regulating MMP-2 and MMP-9

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Chinese Journal of Natural Medicines 2016年第12期14卷 904-912页

作者： Arumugam paramasivam Subramanian Raghunandhakumar Jayaseelan Vijayashree Priyadharsini Gopalswamy Jayaraman Department of Genetics Dr. ALM Post Graduate Institute of Basic Medical Sciences University of Madras Sekkizhar campusTaramani Chennai-600113 India Department of Biochemistry University of Madras Guindy Campus Chennai-600025 India

Thymoquinone(TQ), an active component derived from the medial plant Nigella sativa, has been used for medical purposes for more than 2 000 years. Recent studies have reported that TQ blocked angiogenesis in animal model and reduced migration, adhesion, and invasion of glioblastoma cells. We have recently shown that TQ could exhibit a potent cytotoxic effect and induce apoptosis in mouse neuroblastoma(Neuro-2a) cells. In the present study, TQ treatment markedly decreased the adhesion and migration of Neuro-2a cells. TQ down-regulated MMP-2 and MMP-9 protein expression and m RNA levels and their activities. Furthermore, TQ significantly down-regulated the protein expression of transcription factor NF-κB(p65) but not significantly altered the expression of N-Myc. Taken together, our data indicated that TQ's inhibitory effect on the migration of Neuro-2a cells was mediated through the suppression of MMP-2 and MMP-9 expression, suggesting that TQ treatment can be a promising therapeutic strategy for human malignant neuroblastoma.

关键词： Thymoquinone Neuroblastoma Migration NF-κB MMP-2

Biogenic amines in fresh fish and fishery products and emerging control

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Aquaculture and Fisheries 2023年第4期8卷 431-450页

作者： Abimannan Arulkumar Spiros Paramithiotis Sadayan paramasivam Department of Oceanography and Coastal Area Studies School of Marine SciencesAlagappa UniversityScience CampusKaraikudi630003Tamil NaduIndia Department of Biotechnology Achariya Arts and Science CollegeAffiliated to Pondicherry UniversityVillianurPuducherry605110India Department of Food Science and Human Nutrition Agricultural University of AthensIera Odos 75GR-11855AthensGreece

Occurrence of biogenic amines in fresh fish and fishery products constitute a significant safety *** of histamine is identified as the causative agent of several food poisoning incidences on an annual *** addition,cadaverine,putrescine and tyramine have been recognized as potentiators of histamine *** of biogenic amines in fresh fish and fishery products has been mainly attributed to growth of bacteria possessing amino acid decarboxylase activity,which is facilitated by lack of hygienic conditions and strict temperature control during their *** this end,the effectiveness of traditional and modern approaches to control biogenic amine accumulation has been in the epicenter of intensive *** aim of the present review article is to update and integrate current knowledge regarding the biogenic amine content of fresh fish and fishery products as well as the capacity of traditional and emerging control strategies.

关键词： Fresh fish Cephalopods Crustaceans Shellfish Histamine

Implications of m6A modification in autoimmune disorders

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Cellular & Molecular Immunology 2020年第5期17卷 550-551页

作者： Arumugam paramasivam Jayaseelan Vijayashree Priyadharsini Subramanian Raghunandhakumar Saveetha UniversityChennaiIndia Centre for Biotechnology Anna UniversityChennaiIndia

N6-Methyladenosine(m6A)is the most common and abundant modification of RNA molecules,including mRNAs,microRNAs(miRNAs),and long noncoding RNAs(lncRNAs).1 The m6A modification is catalyzed and dynamically regulated by recently discovered enzymes termed“writers”(methyltransferases including METTL3,METTL14,and WTAP),“erasers”(demethylases including FTO and ALKBH5)and“readers”(m6A-binding proteins including YTHDC1,YTHDC2,YTHDF1,YTHDF2,and YTHDF3).These modifications were recently shown to be involved in the regulation of different biological processes.

关键词： autoimmune m6A modification